Seminars in Colon and Rectal Surgery最新文献

筛选
英文 中文
Anorectal mucosal melanoma 肛门直肠粘膜黑色素瘤
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-12-01 Epub Date: 2023-10-17 DOI: 10.1016/j.scrs.2023.100990
Janet Alvarez MD , J. Joshua Smith MD, PhD
{"title":"Anorectal mucosal melanoma","authors":"Janet Alvarez MD ,&nbsp;J. Joshua Smith MD, PhD","doi":"10.1016/j.scrs.2023.100990","DOIUrl":"10.1016/j.scrs.2023.100990","url":null,"abstract":"<div><p><span>Anorectal mucosal melanoma accounts for less than 1 % of all anorectal malignant tumors and a tendency for delayed diagnosis leads to advanced disease at presentation.</span><span><sup>1</sup></span><sup>,</sup><span><sup>2</sup></span><span><span> Due to the rarity of the disease, there are limited prospective trials exploring the optimal treatment strategies. Generally, tumors are surgically excised, with a preference for conservative management with </span>wide local excision<span><span>. In the past decade, there have been advances with immunotherapy<span> and other targeted therapies. Multiple </span></span>clinical trials continue exploring neoadjuvant/adjuvant combination treatments in the setting of advanced or unresectable disease.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 4","pages":"Article 100990"},"PeriodicalIF":0.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transitions 转换
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-12-01 Epub Date: 2023-10-21 DOI: 10.1016/j.scrs.2023.100991
Thomas E. Read MD, FACS, FASCRS
{"title":"Transitions","authors":"Thomas E. Read MD, FACS, FASCRS","doi":"10.1016/j.scrs.2023.100991","DOIUrl":"10.1016/j.scrs.2023.100991","url":null,"abstract":"","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 4","pages":"Article 100991"},"PeriodicalIF":0.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136009542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to manage a patient with chronic liver disease undergoing colorectal surgery? 如何处理接受结直肠手术的慢性肝病患者?
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-12-01 Epub Date: 2023-10-17 DOI: 10.1016/j.scrs.2023.100986
Benoît Dupont MD , Arnaud Alves MD, PhD
{"title":"How to manage a patient with chronic liver disease undergoing colorectal surgery?","authors":"Benoît Dupont MD ,&nbsp;Arnaud Alves MD, PhD","doi":"10.1016/j.scrs.2023.100986","DOIUrl":"10.1016/j.scrs.2023.100986","url":null,"abstract":"<div><p><span><span>The indications for colorectal surgery in cirrhotic patients have recently been broadened, mostly due to a better understanding and multidisciplinary management of </span>cirrhosis. However, anesthesia and colorectal surgery may both exacerbate deteriorations in liver function in a patient with </span>chronic liver disease<span><span> such that careful preoperative patient selection remains mandatory. Four scores (i.e., Child-Turcotte-Pugh, the Model for End-Stage Liver Disease, Mayo Risk Score, and (VOCAL)-Penn cirrhosis surgical risk score) are currently available to assess the severity of cirrhosis, determine the risk of decompensation, and to estimate postoperative mortality. For colorectal resection to be safely performed electively </span>in patients<span> with compensated liver disease, optimization of the patient is mandatory in the preoperative setting. Preoperative transjugular intrahepatic portosystemic shunt<span> (TIPS) is a promising strategy in patients with portal hypertension, but it requires further evaluation. Similarly, further studies are needed to validate both the feasibility and safety of the laparoscopic approach to colorectal surgery in cirrhotic patients. In summary, preoperative identification and optimization combined with meticulous postoperative care are essential for optimum outcomes in patients with chronic liver disease undergoing colorectal surgery.</span></span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 4","pages":"Article 100986"},"PeriodicalIF":0.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How can the surgeon reduce recurrence after surgery for ileocolic Crohn's disease? 外科医生如何减少回肠结肠性克罗恩病手术后的复发?
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-12-01 Epub Date: 2023-10-17 DOI: 10.1016/j.scrs.2023.100985
Steven R. Brown MD (Professor of Surgery)
{"title":"How can the surgeon reduce recurrence after surgery for ileocolic Crohn's disease?","authors":"Steven R. Brown MD (Professor of Surgery)","doi":"10.1016/j.scrs.2023.100985","DOIUrl":"10.1016/j.scrs.2023.100985","url":null,"abstract":"<div><p>Disease recurrence after surgery for ileocolic Crohn's is common, and repeat surgery is necessary for approximately one-third of patients within ten years. This recurrence rate is influenced by many factors, some of which relate to the disease phenotype. Others may be influenced by the patient (i.e., smoking) or the gastroenterologist with careful disease monitoring and the judicious use of adjuvant medication. The surgeon may also be able to reduce recurrence in the both preoperative preparation of the patient, the timing of surgery, and the intra-operative surgical technique. Evidence of how the surgeon can influence recurrence is discussed in this manuscript, considering current definitions, pathophysiology, and risk factors for recurrence.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 4","pages":"Article 100985"},"PeriodicalIF":0.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135811660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The failed colorectal anastomosis: Turnbull–Cutait as a salvage option 结直肠吻合术失败:特恩布尔切口术作为挽救选择
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-12-01 Epub Date: 2023-10-20 DOI: 10.1016/j.scrs.2023.100988
Carla F. Justiniano MD, MPH , Tracy Hull MD
{"title":"The failed colorectal anastomosis: Turnbull–Cutait as a salvage option","authors":"Carla F. Justiniano MD, MPH ,&nbsp;Tracy Hull MD","doi":"10.1016/j.scrs.2023.100988","DOIUrl":"10.1016/j.scrs.2023.100988","url":null,"abstract":"<div><p><span><span>The incidence of colorectal anastomotic leaks is approximately 5–19 % of cases, posing a threat to intestinal continuity, particularly if the leak arises after a low or ultra-low </span>colorectal anastomosis. A Turnbull–Cutait procedure can be a salvage option for such patients and they may be eligible if they are adequate redo </span>pelvic surgery<span><span> candidates, who are motivated to regain intestinal continuity, and who have good continence and anal function at baseline. The first stage of the procedure is colonic mobilization and pull-through after perineal division at the top of the anorectal complex and mucosectomy. A diverting loop </span>ileostomy<span><span> is utilized. The second stage is amputation of the excess colon and creation of a hand-sewn colo-anal anastomosis, typically performed 7 days later. Outcomes after a Turnbull–Cutait procedure are reasonable based on a series from specialized centers with 80–90 % of patients having a complete Turnbull–Cutait and reversal of the diverting ileostomy. Low anterior resection syndrome is common. In the long-term, studies show that just over half of patients will remain stoma free at 5 years; </span>fecal incontinence is the main reason for failure and return to a stoma. The prospect of a Turnbull–Cutait can be kept in mind when addressing an anastomotic leak in appropriate patients; this may allow for surgical decision-making that makes it feasible to utilize a Turnbull–Cutait in the future.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 4","pages":"Article 100988"},"PeriodicalIF":0.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135965474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local tumor complications in stage IV colorectal cancer 癌症IV期局部肿瘤并发症
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-09-01 Epub Date: 2023-06-07 DOI: 10.1016/j.scrs.2023.100973
Smadar R. Bogardus MD , Gregory K. Low MD
{"title":"Local tumor complications in stage IV colorectal cancer","authors":"Smadar R. Bogardus MD ,&nbsp;Gregory K. Low MD","doi":"10.1016/j.scrs.2023.100973","DOIUrl":"10.1016/j.scrs.2023.100973","url":null,"abstract":"<div><p>Colorectal cancer is associated with distant metastases<span> in 19–26% of patients at initial presentation. Local tumor complications such as obstruction, perforation, and hemorrhage may be identified at initial presentation or may develop during treatment<span> for those that were initially asymptomatic. Optimal management in these situations is dependent on rapid recognition and assessment of the patient's clinical condition, a thorough understanding of oncologic principles, and a multidisciplinary approach to treatment. Given the the reliance on systemic therapy for the management of metastatic disease, it is essential to minimize potential morbidity and mortality to avoid unnecessary treatment delays in this subset of patients. This review highlights the most common local tumor complications seen in the setting of stage IV colorectal cancer and approaches to each.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100973"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46820784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sequence of colorectal and liver resection in patients with surgically-treatable stage IV colorectal cancer 可手术治疗的IV期结直肠癌患者的结肠和肝脏切除顺序
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-09-01 Epub Date: 2023-06-07 DOI: 10.1016/j.scrs.2023.100969
Calista Harbaugh MD, MSc , Aneel Damle MD, MBA
{"title":"Sequence of colorectal and liver resection in patients with surgically-treatable stage IV colorectal cancer","authors":"Calista Harbaugh MD, MSc ,&nbsp;Aneel Damle MD, MBA","doi":"10.1016/j.scrs.2023.100969","DOIUrl":"10.1016/j.scrs.2023.100969","url":null,"abstract":"<div><p>Approximately 25-30% of patients with colorectal cancer develop hepatic metastases<span><span><span>. For patients diagnosed with resectable colorectal hepatic metastases, variation exists regarding the timing of resection of the colorectal primary and the hepatic metastases including three approaches: (1) the “classical” colorectal-first staged approach, (2) the “combined” or simultaneous/synchronous approach, and (3) the “reverse” or liver-first staged approach. The purpose of this chapter is to review the current literature regarding the timing of colorectal and hepatic resection </span>in patients with surgically treatable </span>colorectal adenocarcinoma<span> hepatic metastases. There are inadequate data at the current time to provide definitive recommendations as to the optimal timing and sequence of surgery. Our recommendations based on existing data favor delivery of neoadjuvant therapy<span> followed by either: (1) the combined approach for low-risk resections, (2) the liver-first staged strategy for high-risk hepatic resections or mid- to distal rectal tumors<span> that may benefit from total neoadjuvant therapy, or (3) the colorectal-first approach for symptomatic primary colon tumors.</span></span></span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100969"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41828736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in systemic chemotherapy and immunotherapy for metastatic colorectal cancer 转移性癌症的全身化疗和免疫治疗进展
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-09-01 Epub Date: 2023-06-07 DOI: 10.1016/j.scrs.2023.100972
Nikhil Grandhi MD , Bindiya Patel MD , Olivia Aranha MD, PhD
{"title":"Advances in systemic chemotherapy and immunotherapy for metastatic colorectal cancer","authors":"Nikhil Grandhi MD ,&nbsp;Bindiya Patel MD ,&nbsp;Olivia Aranha MD, PhD","doi":"10.1016/j.scrs.2023.100972","DOIUrl":"10.1016/j.scrs.2023.100972","url":null,"abstract":"<div><p><span>Colorectal cancer is the second leading cause of cancer related death in the United States. Approximately 25% of patients are diagnosed with metastatic colorectal cancer<span><span> (mCRC) and the 5-year survival rate in mCRC is low at 14%. Primary treatment for mCRC is systemic therapy, which includes chemotherapy, </span>immunotherapy, and targeted agents. With advances in genomic profiling, we can now tailor treatment to unique patient populations and improve overall survival. In this review, we discuss treatment strategies for mCRC patients based on tumor sidedness, KRAS/BRAF wild-type versus mutant tumors, and review the benefit of immunotherapy in microsatellite unstable and </span></span>mismatch repair deficient tumors.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100972"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46258258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological trends in stage IV colorectal cancer 结直肠癌IV期流行病学趋势
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-09-01 Epub Date: 2023-06-07 DOI: 10.1016/j.scrs.2023.100967
Jeffrey Roberson MD, Lillias Maguire MD
{"title":"Epidemiological trends in stage IV colorectal cancer","authors":"Jeffrey Roberson MD,&nbsp;Lillias Maguire MD","doi":"10.1016/j.scrs.2023.100967","DOIUrl":"10.1016/j.scrs.2023.100967","url":null,"abstract":"<div><p><span><span><span><span>Epidemiological trends in stage IV colorectal cancer are concerning. As older adults in highly developed countries enjoy decreasing colorectal cancer incidence and mortality, younger patients are developing metastatic disease with increasing frequency, and profound systemic </span>disparities<span><span> persist in screening, treatment, and survival. Globally, the young populations of low- and middle-income countries are exposed to ever higher levels of colorectal </span>cancer risk factors without </span></span>colorectal cancer screening systems in place or ability to provide care, leading to an impending crisis. Scientific discoveries reveal the complex interplay between inherent, tumor-specific, and environmental risks, but the most profound factor underlying the </span>epidemiology of </span>metastatic colorectal cancer is inequality, globally and within the United States.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100967"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46257243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resecting the asymptomatic colon cancer primary in stage IV disease with unresectable metastases 切除无症状结肠癌原发于IV期疾病并有不可切除的转移
IF 0.3
Seminars in Colon and Rectal Surgery Pub Date : 2023-09-01 Epub Date: 2023-06-07 DOI: 10.1016/j.scrs.2023.100971
Kristen A. Ban MD, MS
{"title":"Resecting the asymptomatic colon cancer primary in stage IV disease with unresectable metastases","authors":"Kristen A. Ban MD, MS","doi":"10.1016/j.scrs.2023.100971","DOIUrl":"10.1016/j.scrs.2023.100971","url":null,"abstract":"<div><p>Many patients with synchronous metastatic colorectal cancer<span> (CRC) are asymptomatic from the primary tumor. While primary tumor resection is indicated for symptoms including bleeding, obstruction, and perforation, the role for asymptomatic primary tumor resection has been debated. Studies in favor of and against primary tumor resection are reviewed. Unlike previously published non-randomized studies, whose results may have been strongly influenced by selection bias, recently published randomized controlled trials<span> suggest that primary tumor resection in Stage IV CRC with an asymptomatic primary and unresectable metastatic disease does not provide a survival benefit to the patient.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100971"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41344677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书