{"title":"Epidemiological trends in stage IV colorectal cancer","authors":"Jeffrey Roberson MD, Lillias Maguire MD","doi":"10.1016/j.scrs.2023.100967","DOIUrl":"10.1016/j.scrs.2023.100967","url":null,"abstract":"<div><p><span><span><span><span>Epidemiological trends in stage IV colorectal cancer are concerning. As older adults in highly developed countries enjoy decreasing colorectal cancer incidence and mortality, younger patients are developing metastatic disease with increasing frequency, and profound systemic </span>disparities<span><span> persist in screening, treatment, and survival. Globally, the young populations of low- and middle-income countries are exposed to ever higher levels of colorectal </span>cancer risk factors without </span></span>colorectal cancer screening systems in place or ability to provide care, leading to an impending crisis. Scientific discoveries reveal the complex interplay between inherent, tumor-specific, and environmental risks, but the most profound factor underlying the </span>epidemiology of </span>metastatic colorectal cancer is inequality, globally and within the United States.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100967"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46257243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resecting the asymptomatic colon cancer primary in stage IV disease with unresectable metastases","authors":"Kristen A. Ban MD, MS","doi":"10.1016/j.scrs.2023.100971","DOIUrl":"10.1016/j.scrs.2023.100971","url":null,"abstract":"<div><p>Many patients with synchronous metastatic colorectal cancer<span> (CRC) are asymptomatic from the primary tumor. While primary tumor resection is indicated for symptoms including bleeding, obstruction, and perforation, the role for asymptomatic primary tumor resection has been debated. Studies in favor of and against primary tumor resection are reviewed. Unlike previously published non-randomized studies, whose results may have been strongly influenced by selection bias, recently published randomized controlled trials<span> suggest that primary tumor resection in Stage IV CRC with an asymptomatic primary and unresectable metastatic disease does not provide a survival benefit to the patient.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100971"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41344677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Colorectal liver metastases: Resect, ablate, or embolize","authors":"Natasha Leigh MD, Dominic E. Sanford MD","doi":"10.1016/j.scrs.2023.100968","DOIUrl":"10.1016/j.scrs.2023.100968","url":null,"abstract":"<div><p>The management of colorectal liver metastases<span> (CRLM) is complex and should be individualized to each patient. Resectable CRLM benefit from surgical resection, preferably minimally invasive and parenchymal sparing, when feasible. Ablation is a viable alternative. Chemotherapy in this setting is potentially indicated in select patients, however, it has a clear role in unresectable CRLM. Newer locoregional therapies<span> may benefit some unresectable CRLM with resistance to chemotherapy. Liver transplantation, a new therapy on the horizon for unresectable disease, has encouraging preliminary long-term survival outcomes for carefully selected patients.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100968"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46040066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Loftus MD , Richard Hoehn MD , Timothy Nywening MD, MS, MPHS
{"title":"Evolving role of cytoreduction and HIPEC for colorectal cancer","authors":"Alexander Loftus MD , Richard Hoehn MD , Timothy Nywening MD, MS, MPHS","doi":"10.1016/j.scrs.2023.100970","DOIUrl":"10.1016/j.scrs.2023.100970","url":null,"abstract":"<div><p><span>Peritoneal metastases<span> from colorectal cancer have a dismal natural history and poor response to systemic chemotherapy. Cytoreductive surgery<span>, the mainstay of locoregional control of peritoneal carcinomatosis<span>, with hyperthermic intraperitoneal chemotherapy (HIPEC) has shown survival benefit in selected patients. While recent studies such as the PRODIGE 7 trial have not demonstrated added benefit of HIPEC, these trials have limitations (i.e. choice of HIPEC agent, patient population), and more studies are needed. The efficacy of prophylactic HIPEC </span></span></span></span>in patients at high risk for peritoneal recurrence remains controversial. Ongoing trials, including intraperitoneal delivery of novel anti-cancer agents, may yield significant new therapeutic options.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 3","pages":"Article 100970"},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45898038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stoma prolapse","authors":"Saher-Zahra Khan MD, Emily Steinhagen MD","doi":"10.1016/j.scrs.2023.100958","DOIUrl":"https://doi.org/10.1016/j.scrs.2023.100958","url":null,"abstract":"<div><p>Stoma prolapse is a common late complication that approximately 30% of ostomates experience. Interventions vary from simple local revisions to trans-abdominal approaches for resection and re-siting of the prolapsed stoma. Definitively addressing stoma prolapse frequently requires surgical treatment of an associated parastomal hernia. Stoma prolapse infrequently leads to incarceration or strangulation requiring emergent surgical intervention. The decisions regarding intervention depend on acuity of patient presentation, the severity of the prolapse, and patient fitness for operative intervention.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 2","pages":"Article 100958"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49724501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High ileostomy output: A practical review of pathophysiology, causes, and management✰","authors":"Harold J. Boutté Jr. MD , Vitaliy Poylin MD, MBA","doi":"10.1016/j.scrs.2023.100955","DOIUrl":"10.1016/j.scrs.2023.100955","url":null,"abstract":"<div><p><span>Ileostomies are commonly created for a variety of </span>gastrointestinal disease<span><span>; however, anatomic and physiologic alterations often render ileostomy patients vulnerable to high outputs, dehydration, and electrolyte derangements. Proactive dietary, medical, and behavioral strategies can decrease ileostomy outputs and minimize complications related to high outputs. This article discusses physiology and pathophysiology relating to ileostomies and high-output ileostomies. Diagnostic assessments, work-up, and </span>treatment options for patients with high output ileostomies are thoroughly reviewed through the lens of a healthcare provider.</span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 2","pages":"Article 100955"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42729060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Practical tips and tricks for stoma creation under difficult situations","authors":"Joy Chen MD, Mukta Krane MD","doi":"10.1016/j.scrs.2023.100953","DOIUrl":"10.1016/j.scrs.2023.100953","url":null,"abstract":"<div><p>Patients undergoing colorectal surgery may need a stoma for a variety of clinical or disease related factors. Stoma creation can result in short- and long-term complications particularly when performed in demanding situations. In addition, a problematic stoma may have longstanding implications for overall functional outcomes and patient satisfaction. This manuscript seeks to identify high risk patient populations for challenging stoma creation and pragmatic techniques to mitigate complications.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 2","pages":"Article 100953"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46894069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Devin Boehm BS, Jonathan Rosenfeld BS, Emily Ji MD, Ziho Lee MD
{"title":"A review of bowel-based urinary diversions for the colorectal surgeon","authors":"Devin Boehm BS, Jonathan Rosenfeld BS, Emily Ji MD, Ziho Lee MD","doi":"10.1016/j.scrs.2023.100960","DOIUrl":"10.1016/j.scrs.2023.100960","url":null,"abstract":"<div><p>After bladder removal, bowel is commonly utilized in the construction of a urinary diversion. There are two types of urinary diversions: incontinent diversions, in which urine continuously drains from a stoma; and continent diversions, in which urine does not freely drain from a stoma. Continent diversions may further be subcategorized as orthotopic, in which voiding occurs via the native urethra; and continent cutaneous, in which voiding occurs via clean intermittent catheterization. Herein, we review the most common types of urinary diversions and their relevant complications.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 2","pages":"Article 100960"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41506786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth A. Rauh BSN, RN , Janice C. Colwell APRN
{"title":"A stoma nurse's wishlist to surgeons: Tips for before, during, and after stoma creation","authors":"Elizabeth A. Rauh BSN, RN , Janice C. Colwell APRN","doi":"10.1016/j.scrs.2023.100951","DOIUrl":"10.1016/j.scrs.2023.100951","url":null,"abstract":"<div><p>Ongoing partnership between the surgeon, ostomy nurse, and patient beginning before surgery and continuing past surgery increases the likelihood of the patient's independence and confidence in ostomy care and decreases complications. This article provides tips and wish lists created by ostomy nurses to address the importance of preoperative patient education and stoma site marking, ideal stoma characteristics, basic ostomy care, the role of the ostomy nurse in follow-up care, and common ostomy complications.</p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 2","pages":"Article 100951"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41335647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient education for stoma patients","authors":"Adrian Rosenberg BA , Michael McGee MD","doi":"10.1016/j.scrs.2023.100952","DOIUrl":"10.1016/j.scrs.2023.100952","url":null,"abstract":"<div><p>The distress of stoma creation coupled with the ubiquity of stomas renders stoma-related care and education an underserved orphan interest. Fortuitously, multiple educational resources exist to help empower patients to adapt to life with an ostomy<span>, improve their quality of life<span>, and reduce complications and readmissions. Patients and their home caregivers should be educated pre- and post-operatively to understand their stoma to improve their quality of life, decrease preventable complications, and decrease health system resource utilization. A variety of outpatient stoma support groups and internet resources provide a venue for ongoing educational support for the ostomate.</span></span></p></div>","PeriodicalId":55956,"journal":{"name":"Seminars in Colon and Rectal Surgery","volume":"34 2","pages":"Article 100952"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44319520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}