Practica Medicala最新文献_第6页

The influence of lymphocyte to monocyte ratio on the postoperative outcome of patients diagnosed with advanced stage ovarian cancer 淋巴细胞/单核细胞比值对晚期卵巢癌患者术后预后的影响

Practica Medicala Pub Date : 2022-08-15 DOI: 10.37897/rjmp.2022.s3.5

S. Petrea, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, Tarig Massawi, Alexandru Ristea

{"title":"The influence of lymphocyte to monocyte ratio on the postoperative outcome of patients diagnosed with advanced stage ovarian cancer","authors":"S. Petrea, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, Tarig Massawi, Alexandru Ristea","doi":"10.37897/rjmp.2022.s3.5","DOIUrl":"https://doi.org/10.37897/rjmp.2022.s3.5","url":null,"abstract":"Introduction: the lymphocyte to monocyte ratio has been widely investigated in patients with different malignancies and proved to have prognostic value for both early and long-term evolution. Aim: Current paper investigates the influence of this parameter on the perioperative course of patients submitted to surgery for advanced stage ovarian cancer. Material and methods: between 2016-2018 there were 34 patients diagnosed with advanced stage ovarian cancer who were submitted to surgery with curative intent and in whom this parameter was evaluated. Results: a low rate of this parameter seemed to be significantly associated with a more advanced stage at diagnostic (p=0,002), with higher risk of the presence of lymph node metastases (p=0,003), with larger residual tumor (p=0,002). Meanwhile, patients with a lower lymphocyte to monocyte ratio usually had a higher level of CA 125, but this fact did not have statistical significance (p=0,87). Conclusions: patients with a lower lymphocyte to monocyte rate are expected to present more aggressive ovarian tumors and therefore a personalized therapeutic strategy might be needed.","PeriodicalId":55841,"journal":{"name":"Practica Medicala","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41893092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does the preoperative thrombocytosis influence the postoperative outcomes in cervical cancer? 术前血小板增多对宫颈癌术后预后有影响吗?

Practica Medicala Pub Date : 2022-08-15 DOI: 10.37897/rjmp.2022.s3.10

A. Ciulcu, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, B. Gașpar

引用次数: 0

The influence of platelet counts on the postoperative outcome of patients with advanced stage ovarian cancer 血小板计数对晚期卵巢癌患者术后预后的影响

Practica Medicala Pub Date : 2022-08-15 DOI: 10.37897/rjmp.2022.s3.1

A. Ciulcu, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, Tarig Massawi

{"title":"The influence of platelet counts on the postoperative outcome of patients with advanced stage ovarian cancer","authors":"A. Ciulcu, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, Tarig Massawi","doi":"10.37897/rjmp.2022.s3.1","DOIUrl":"https://doi.org/10.37897/rjmp.2022.s3.1","url":null,"abstract":"Introduction: Ovarian cancer represents one of the most aggressive gynecological malignancies which is associated with poor rates of survival especially if surgery with curative intent is not feasible. Aim: The current paper analyzes the correlation ship between the preoperative number of platelets and the perioperative outcomes of patients submitted to primary cytoreduction for ovarian cancer. Material and methods: between 2016-2018, 34 patients with advanced stage ovarian cancer were submitted to surgery; among these patients there were 21 cases with a preoperative platelet number lower than 450.000/microliter and 13 cases with higher than 450.000/microliter values. Results: higher serum levels of platelets were significantly associated with more advanced stages at the time of the diagnostic, higher tumoral burden (defined as a peritoneal cancer index higher than 20) and lower rates of complete debulking surgery. Meanwhile, these patients reported a significantly higher rate of postoperative complications. Conclusions: patients presenting a platelet number higher than 450.000/microliter are associated with worse perioperative outcomes after debulking surgery for advanced stage ovarian cancer.","PeriodicalId":55841,"journal":{"name":"Practica Medicala","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44181336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular reconstructions using synthetic prostheses after extended pancreatic resections for locally advanced pancreatic cancer 局部晚期胰腺癌扩大胰腺切除术后人工血管重建的研究

Practica Medicala Pub Date : 2022-08-15 DOI: 10.37897/rjmp.2022.s3.11

N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, Tarig Massawi, B. Gaspar

引用次数: 0

Is intraperitoneal chemotherapy beneficial in pancreatic cancer? 腹腔化疗对胰腺癌有益吗?

Practica Medicala Pub Date : 2022-06-30 DOI: 10.37897/rjmp.2022.2.9

I. Bălescu, N. Bacalbaşa, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu, Tarig Massawi

引用次数: 0

The correlation between the number of platelets and endometrial pathology 血小板数量与子宫内膜病理的关系

Practica Medicala Pub Date : 2022-06-30 DOI: 10.37897/rjmp.2022.2.8

A. Ciulcu, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu

{"title":"The correlation between the number of platelets and endometrial pathology","authors":"A. Ciulcu, N. Bacalbaşa, I. Bălescu, C. Stoica, L. Pop, V. Varlas, Cristina Martac, Andrei Voichitoiu","doi":"10.37897/rjmp.2022.2.8","DOIUrl":"https://doi.org/10.37897/rjmp.2022.2.8","url":null,"abstract":"Introduction. Circulating platelets play an essential role in the immune system and furthermore in tumor development and proliferation. Therefore, the correlation between different neoplasia and the number of platelets has been widely studied. The aim of the current paper is to investigate the correlation ship between platelet number and tumoral endometrial transformation. Material and methods. Between January 2022 and June 2022 22 patients with endometrial hyperplasia or endometrial cancer were submitted to surgery. The serum levels of platelets were determined and compared to those reported in a similar group of patients in whom the endometrial lining was normal. Results. Patients diagnosed with endometrial cancer presented a significantly higher number of platelets as well as a significantly higher platelet volume when compared to patients diagnosed with endometrial hyperplasia and respectively to those in whom a normal endometrial lining was found. Conclusions. The serum number of platelets and their volume seem to be positively correlated with the aggressivity of the tumoral transformation of the endometrial lining and should be therefore considered as part of the elements which should be analyzed when discussing the best therapeutic option in such patients.","PeriodicalId":55841,"journal":{"name":"Practica Medicala","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44497106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlates of Fear of Cancer Progression during COVID-19 in Romania 罗马尼亚新冠肺炎期间对癌症进展的恐惧相关性

Practica Medicala Pub Date : 2022-06-30 DOI: 10.37897/rjmp.2022.2.4

F. Medrea, Kállay Éva, Degi L. Csaba

{"title":"Correlates of Fear of Cancer Progression during COVID-19 in Romania","authors":"F. Medrea, Kállay Éva, Degi L. Csaba","doi":"10.37897/rjmp.2022.2.4","DOIUrl":"https://doi.org/10.37897/rjmp.2022.2.4","url":null,"abstract":"Objectives. Fear of cancer progression (FoP) is one of patients’ greatest concerns and one of the most reported unmet needs. Higher levels of FoP can negatively impact a patient’s quality of life, impairing physical, emotional, social and functional well-being. The Romanian health-care system has difficulties in offering qualitative psychosocial assistance for cancer outpatients. Due to their specific implications, the COVID-19 pandemic restrictions might further affect FoP, therefore our objective was to investigate correlates of FoP in cancer outpatients during the COVID-19 pandemic in Romania. Material and methods. The study investigated correlates of FoP in 330 Romanian cancer outpatients assessed during 2021. T-tests, Multivariate General Linear Models and Hierarchical Regression Models were conducted in order to assess the relationship between variables. Outcomes. Results showed differences in the assessed variables depending on gender (women had scores significantly higher than men regarding FoP and illness intrusiveness) and marital status. Moreover, using a hierarchical regression model, we identified three statistically significant predictors of FoP: gender, illness intrusiveness regarding relationships and anxiety, together explaining 38.2% of the variance in global FoP scores. Anxiety was the most important predictor of FoP, explaining 21.3% of the variance in the FoP scores, 5 times more than gender and almost 2 times more than illness intrusiveness in interpersonal relationships. Conclusions. Cancer is a complex experience, impacted by both socio-demographic variables such as gender and marital status, as well as psychological variables such as anxiety and fear of disease progression. Individualized psychosocial-care should be recognized as essential, and personalized interventions should be integrated into the patient's treatment plan.","PeriodicalId":55841,"journal":{"name":"Practica Medicala","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46687755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal and fetal alloimmune thrombocytopenia 新生儿和胎儿同种免疫性血小板减少症

Practica Medicala Pub Date : 2022-06-30 DOI: 10.37897/rjmp.2022.2.1

Ioana Emanuela Atanasescu, N. Gică, R. Botezatu, G. Peltecu, A. Panaitescu

{"title":"Neonatal and fetal alloimmune thrombocytopenia","authors":"Ioana Emanuela Atanasescu, N. Gică, R. Botezatu, G. Peltecu, A. Panaitescu","doi":"10.37897/rjmp.2022.2.1","DOIUrl":"https://doi.org/10.37897/rjmp.2022.2.1","url":null,"abstract":"Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the result of maternal alloantibodies interaction with human platelets antigen. Maternal alloantibodies are generated following the contact of maternal immune system with paternally acquired antigens on the fetal human platelets (PLTs). HPA-1a alloantibodies are responsible for more than 80% of cases of FNAIT. Low prevalence of FNAIT that occurs in less than 1 case out of 1000 births, and even a lower risk for intracranial hemorrhage makes a controversial discussion whether a screening in pregnant patients would bring benefits. Concerning pathogenesis of FNAIT, it has been shown that fetal platelets caring HPA-1a antigen enters maternal circulation and produce an immune response, that leads to production of HPA-1a maternal antibodies that afterwards can pass the placenta causing fetal thrombocytopenia. The majority of mothers who gave birth to a newborn with FNAIT usually are asymptomatic, although they might have a previous affected pregnancy. Although management of pregnancies complicated by FNAIT is still in discuss and controversial, a systemic review studies in 2017 showed that best guidance and delivery for pregnancies that are at risk for FNAIT is a weekly maternal administration of intravenous immunoglobulin, adding glucocorticoids depending on severity of FNAIT.","PeriodicalId":55841,"journal":{"name":"Practica Medicala","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48869939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic Wax-Up - an extremely important method of communication between the dental office and the dental laboratory 诊断蜡-牙科办公室和牙科实验室之间极其重要的沟通方法

Practica Medicala Pub Date : 2022-06-30 DOI: 10.37897/rjmp.2022.2.2

S. Drafta, V. Perieanu, R. Costea, O. Eftene, M. Burlibașa, Raluca Maria Manea, Florentina Caministeanu, Mircea Carabela, ioana-Cristina neagoe, Raluca Costea, I. Beuran, N. Măru

引用次数: 0

Depression and anxiety at the global conceptual level in primary care 初级保健中抑郁和焦虑的全球概念水平

Practica Medicala Pub Date : 2022-06-30 DOI: 10.37897/rjmp.2022.2.5

Andreea-Laura Ionescu, I. Grăjdeanu, A. Stănescu

引用次数: 0