IMC Journal of Medical Science最新文献

{"title":"Seroprevalence of SARS-CoV-2 IgG antibodies among rural children aged 6-14 years in a selected block of West Bengal, India","authors":"Vineeta Shukla, Vivek Shukla, Mausumi Basu, Aparajita Mondal, Mamunur Rashid, Ripan Saha","doi":"10.55010/imcjms.18.022","DOIUrl":"https://doi.org/10.55010/imcjms.18.022","url":null,"abstract":"Background and objectives: Children comprised a significant part of the population during the second and third waves of the COVID-19 pandemic. The objectives of this study were to estimate the seroprevalence of COVID-19 IgG antibody among the children aged 6 to 14 years and to determine, if any, the factors associated with seropositivity.\u0000\u0000Methods: This cross-sectional study was conducted in a selected block of West Bengal, India over a period of 1 year (April 2022-March 2023) among children. Thirty villages in the block were selected by cluster sampling technique. COVID-19 IgM/IgG Rapid Antibody Test Kit (ICMR approved) was used for the detection of SARS-CoV-2 IgG antibodies. Data were analyzed by appropriate statistical tests.\u0000\u0000Results: Total 600 children were enrolled in the study.SARS-CoV-2 IgG antibody was positive in 57.2% children. The seropositivity rate (91.8%) was significantly (p<0.001) high among children of age group 12 to 14 years. Seropositivity rate was not significantly different between male and female children (46.4% vs. 53.6%; p>0.05).\u0000\u0000Conclusion: SARS-COV-2 IgG antibody was positive in a high proportion of children residing in rural areas indicating asymptomatic coronavirus infections among rural population. Socio-demographic factors such as higher age group and father’s education were significantly associated with seropositivity.\u0000\u0000July 2024; Vol. 18(2):010. DOI:https://doi.org/10.55010/imcjms.18.022\u0000\u0000*Correspondence: Vineeta Shukla, Department of Community Medicine, Infectious Diseases and Beliaghata General Hospital, Kolkata, India. Email: vineeta1992@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141655405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mustard oil consumption and Harris platelet syndrome: unveiling a dietary link to thrombocytopenia in the Indian subcontinent","authors":"Wasim Ul Haque","doi":"10.55010/imcjms.18.021","DOIUrl":"https://doi.org/10.55010/imcjms.18.021","url":null,"abstract":"Background and objectives: Asymptomatic thrombocytopenia, characterized by a reduced platelet count without bleeding symptoms, is notably prevalent in certain regions of India and Bangladesh, presenting a diagnostic challenge. A significant portion of healthy blood donors from Bangladesh and various parts of India, particularly West Bengal, exhibit this condition, termed Harris platelet syndrome (HPS). This review explores the potential correlation between mustard oil consumption, a common dietary staple in these regions, and the incidence of HPS.\u0000\u0000Methods: A comprehensive narrative review was conducted using systematic search strategies across databases such as Google Scholar, MEDLINE, PubMed, and Scopus. Keywords included \"Harris platelet syndrome,\" \"mustard oil consumption,\" \"thrombocytopenia,\" and \"erucic acid.\" Studies were selected based on relevance and quality, focusing on the epidemiology of HPS, dietary habits, and the thrombocytopenic effects of erucic acid.\u0000\u0000Results: HPS shows a significant geographical prevalence in the Indian subcontinent, notably in regions like West Bengal, Kashmir, and Assam. The review identifies a higher prevalence of thrombocytopenia in areas with predominant mustard oil usage. Studies highlight the association between dietary erucic acid from mustard oil and thrombocytopenia, with notable effects observed in patients treated with Lorenzo’s Oil, which contains erucic acid.\u0000\u0000Conclusions: The review highlights a significant association between mustard oil consumption and asymptomatic thrombocytopenia in the Indian subcontinent. The similarity in hematological profiles between HPS and erucic acid-induced thrombocytopenia underscores the need for further research. This includes measuring erucic acid levels in patients, conducting controlled dietary interventions, and genetic analyses to differentiate between genetic and environmental factors.\u0000\u0000July 2024; Vol. 18(2):009. DOI:https://doi.org/10.55010/imcjms.18.021\u0000\u0000*Correspondence: Wasim Md MohosinUl Haque, Department of Nephrology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), 122 Kazi Nazrul Islam Avenue, Dhaka-1000, Bangladesh. Email: wmmhaque@live.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety levels and influencing factors among the relatives of patients presenting to the emergency department","authors":"S. Sezgin, Hakan Topaçoğlu, Özlem Dikme, Özgür Dikme, Şennaz Şahin, Sıla Şadıllıoğlu","doi":"10.55010/imcjms.18.020","DOIUrl":"https://doi.org/10.55010/imcjms.18.020","url":null,"abstract":"Background and objective: In recent years, the majority of incidents of increasing violence against healthcare workers, especially emergency department (ED) staff, have been perpetrated by family members of patients. Anxiety is one of the predictors of this violence in ED. The aims of this study were to measure anxiety levels among the relatives of ED patients at the time of presentation and to identify the factors that affect them.\u0000\u0000Materials and methods: In this prospective, cross-sectional study, 687 relatives of patients were included. The State-Trait Anxiety Inventory- State (STAI-S) and State-Trait Anxiety Inventory- Trait (STAI-T) scales were administered to assess state and trait anxiety levels. The data for the study were recorded using the SPSS 16.0 statistics program.\u0000\u0000Results: STAI-S averages were found to be statistically significantly higher than their STAI-T averages in parents (p = 0.036). A statistically significant difference was found between the state and trait anxieties of the group whose patients had a history of previous hospitalization (p = 0.013), previous surgeries (p = 0.009), presented with trauma (p=0.007), and received intervention in ED (p = 0.003). The state anxiety of the patient relatives who brought their patients to the ED by their own means was found to be statistically significantly higher than the trait anxiety (p=0.028).\u0000\u0000Conclusion: Our study showed that patient relatives whose patients presented to the ED due to trauma or had a history of surgery/hospitalization, or arrived at the hospital under their own means, experienced elevated anxiety levels. More multi-center studies are needed.\u0000\u0000July 2024; Vol. 18(2):008. DOI: https://doi.org/10.55010/imcjms.18.020\u0000\u0000*Correspondence: Seçkin Bahar Sezgin, Emergency Department,Gaziantep City Hospital, Gaziantep, Turkey. Email: seckinbahar34@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"14 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between mustard oil consumption and thrombocytopenia: a case-control study in Bangladesh","authors":"Wasim Ul Haque, Mashud Alam, Akm Shaheen Ahmed, Arif Mahmud","doi":"10.55010/imcjms.18.017","DOIUrl":"https://doi.org/10.55010/imcjms.18.017","url":null,"abstract":"Background and objectives: Mustard oil, a common ingredient in South Asian cuisine, has been associated with both culinary appeal and potential health benefits. While studies suggest its role in reducing the risk of ischemic heart disease, concerns arise due to the presence of erucic acid, which has been linked to adverse cardiovascular effects and thrombocytopenia. This case-control study aimed to investigate the association between mustard oil consumption and thrombocytopenia in the Bangladeshi population.\u0000\u0000Materials and methods: Consecutive patients diagnosed with thrombocytopenia (platelet count < 150000/µL) were enrolled as cases, while controls were selected as the next consecutive patients with normal platelet counts, regardless of demographic characteristics or disease status. Data on demography, clinical variables and mustard oil consumption were collected from medical records and face-to-face interviews.\u0000\u0000Results: Seventy-six participants were included in the study of which 38 belonged to case and 38 to control groups. The mean age of the individuals in control and case groups was 57.5 and 58.2 years respectively (p = 0.808). Notably, 83.3% of cases reported using mustard oil compared to 28.3% of controls (p<0.001). Cases exhibited significantly (p < 0.001) lower platelet counts (114,789 ± 24,453 /µL) compared to controls (278,211 ± 84,595 /µL). Male gender and the use of mustard oil in cooking were identified as predictors of thrombocytopenia. No bleeding symptoms were observed, raising questions about the clinical significance of mustard oil-associated thrombocytopenia.\u0000\u0000Conclusion: The study underscores the need for further research to elucidate the complex relationship between mustard oil consumption, erucic acid, and thrombocytopenia, emphasizing the importance of dietary habits in health outcomes.\u0000\u0000July 2024; Vol. 18(2):005 DOI: https://doi.org/10.55010/imcjms.18.017\u0000\u0000*Correspondence: Wasim Md Mohosin Ul Haque, Department of Nephrology, BIRDEM General Hospital, 122 Kazi Nazrul Islam Avenue, Dhaka 1000, Bangladesh. Email: wmmhaque@live.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"57 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141123425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pleomorphic adenoma of the submandibular gland: a case report","authors":"Vijay Kumar, Tanweerul Huda, Zeeshan Ahmad, Rohit Kumar, Mohd. Yasir Zubair","doi":"10.55010/imcjms.18.016","DOIUrl":"https://doi.org/10.55010/imcjms.18.016","url":null,"abstract":"Salivary gland tumors are relatively rare and constitute only about 1-4 % of head and neck tumors. Pleomorphic adenoma (PA) is the most common benign tumor of salivary glands. Approximately 80% of pleomorphic adenomas occur in the parotid gland, rest 10-20% in submandibular and minor salivary glands. Here, we present a confirmed case of pleomorphic adenoma of the submandibular gland.\u0000\u0000July 2024; Vol. 18(2):004. DOI: https://doi.org/10.55010/imcjms.18.016\u0000\u0000*Correspondence: Zeeshan Ahmad, Department of Otorhinolaryngology, ESIC Medical College Hospital, Bihta , Patna - 801103, Bihar, India. Email: ahmad66zeeshan@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extended spectrum beta-lactamase production and blaCTX-M gene in Escherichia coli and Klebsiella pneumoniae causing urinary tract infection at a tertiary care hospital in Nepal","authors":"Gaurab Pandey, Anmol Karki, Prashant Karki, Chattra Thapa","doi":"10.55010/imcjms.18.014","DOIUrl":"https://doi.org/10.55010/imcjms.18.014","url":null,"abstract":"Background and objective: Urinary tract infections (UTIs) are the most common bacterial infections where Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) are the predominating pathogens. These pathogens have a high rate of antibiotic resistance and exhibit the production of extended-spectrum beta-lactamase (ESBL). This study investigated the antibiotic resistance pattern and ESBL production of E. coli and K. pneumoniae isolated from patients with UTIs attending a tertiary care hospital in Nepal by both phenotypic and genotypic techniques.\u0000\u0000Materials and methods: A cross-sectional study was performed where 4664 mid-stream urine specimens from suspected UTI cases were cultured. Isolated E. coli and K. pneumoniae were subjected to antibiotic susceptibility testing by Kirby Bauer disc diffusion method. Genotypic detection of blaCTX-M gene was performed using polymerase chain reaction (PCR).\u0000\u0000Results: Out of 4664 urine samples processed, 564 (12.1%) were positive for E. coli (475, 10.2%) and K. pneumonia (89, 1.9%). Out of the total 564 studied samples, 267 (47.3%) were MDR isolates (E. coli: 222, 46.7%; K. pneumoniae: 45, 50.6%) and 96 (17%) were positive for ESBL by double disc confirmatory test. Out of 24 ESBL positive E. coli and 6 K. pneumoniae, 19 (79.2%) and 3 (50%) respectively were positive for blaCTX-M gene.\u0000\u0000Conclusion: This study indicates high prevalence of MDR and ESBL producing E. coli and K. pneumoniae causing UTIs at an urban hospital setting in Nepal.\u0000\u0000July 2024; Vol. 18(2):002. DOI: https://doi.org/10.55010/imcjms.18.014\u0000\u0000*Correspondence: Gaurab Pandey, Department of Medical Laboratory Science, Nobel College Affiliated to Pokhara University, Kathmandu, Nepal. Email: pandeygaurab67@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"48 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140721608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends of COVID-19 mortality and hospitalization rates in southern states of the United States, 2020-2023","authors":"Bever-Leigh Holden, Precious Patrick Edet, Elizabeth A.K. Jones, Amal K. Mitra","doi":"10.55010/imcjms.18.013","DOIUrl":"https://doi.org/10.55010/imcjms.18.013","url":null,"abstract":"ackground and Objectives: The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has emerged as one of the most profound global health crises of the 21st century. In the United States, the impact of COVID-19 has been severe, with notable disparities observed in the Southern region. This study aims to evaluate trends in COVID-19 mortality and hospitalization rates in southern states over the course of 2020 to 2023 by presenting a comprehensive analysis of trends in COVID-19 outcomes within Southern states.\u0000\u0000Methods: Data for the study was collected from the COVID-19 Data Tracker, a resource provided by the Centers for Disease Control and Prevention (CDC). Stratification techniques were employed to categorize the sample into subgroups of Southern states (Arkansas, Alabama, Florida, Georgia, Kentucky, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee, Texas, and Virginia). Joinpoint regression models were used to calculate Annual Percentage Change (APC) and Average Annual Percentage Change (AAPC).\u0000\u0000Results: Results showed a downward trend in both age adjusted APC and AAPC COVID-19 hospitalization rates and an upward trend in mortality rates for all southern states between 2020 to 2023. Only 3 out of the 12 states have age adjusted mortality rates that are lower than the national age adjusted mortality rate for COVID-19 (286.4 deaths per 100,000). COVID-19 vaccine coverage in 12 southern states is 61.8% - 91.3%.\u0000\u0000Conclusion:The study contributes to a deeper understanding of the evolving dynamics of COVID-19 pandemic within the southern U.S. states. The information would be a valuable guidance for public health strategies, resource allocation, and policymaking aimed at addressing this ongoing crisis.\u0000\u0000July 2024; Vol. 18(2):001. DOI: https://doi.org/10.55010/imcjms.18.013\u0000\u0000*Correspondence: Bever-Leigh Holden, Jackson State University, Department of Epidemiology and Biostatistics, Jackson, Mississippi, USA, Email:bever-leigh.i.holden@students.jsums.edu; beverleighholden@yahoo.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140723735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue in Bangladesh and neighboring countries: an overview of epidemiology, transmission, control, and prevention","authors":"M. S. Zaman, Amal K. Mitra","doi":"10.55010/imcjms.18.012","DOIUrl":"https://doi.org/10.55010/imcjms.18.012","url":null,"abstract":"Background and Objectives: Dengue fever, caused by four serotypes of the dengue virus (DENV), is a global health threat, affecting millions of people annually, with a significant burden in Asian countries. Bangladesh, where dengue was first documented in the 1960s, has witnessed an escalation of cases in recent years. The aim of this review is to provide an overview on dengue covering dengue epidemiology in Bangladesh and neighboring countries, efficacy of available vaccines, diagnostic tests and preventive measures.\u0000\u0000Materials and Methods: A narrative review was conducted using the keywords such as dengue in Bangladesh, dengue in South and Southeast Asia, epidemiology, genomic structure, transmission, diagnosis, vaccines and prevention. The information and data of this article were drawn from extensively reviewed scientific journals and pertinent authoritative sources. The data search was limited from year 2000 to 2023.\u0000\u0000Results: Magnitude of dengue infection in Bangladesh and neighboring countries was assessed. The usefulness of diagnostic tests as well as the prospect of available vaccines was reviewed. Control and preventive measures to mitigate spread and transmission of the disease were also discussed.\u0000\u0000Conclusion: Effective prevention and control of dengue needs coordinated efforts in surveillance, research, control and preventive measures. This holistic approach is necessary to mitigate detrimental consequences of dengue on public health and economies worldwide.\u0000\u0000IMC J Med Sci. 2024; 18(1):012. DOI: https://doi.org/10.55010/imcjms.18.012\u0000\u0000*Correspondence: M. S. Zaman, Department of Biological Sciences, Alcorn State University, Lorman, Mississippi, USA. Email: zaman@alcorn.edu; mzaman@southtexascollege.edu","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"5 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139592810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified MacConkey agar: a simple selective medium for isolation of Burkholderia pseudomallei from soil","authors":"Salvinaz Islam Moutusy, S. Farook, Sraboni Mazumder, L. Barai, K.M. Shahidul Islam, Md Shariful Alam Jilani","doi":"10.55010/imcjms.18.011","DOIUrl":"https://doi.org/10.55010/imcjms.18.011","url":null,"abstract":"Background and objectives:A selective medium is required for isolation of Burkholderia pseudomallei from soil. The present study aimed to develop an easy to prepare selective media by modifying MacConkey agar medium for improved isolation of B. pseudomallei from soil.\u0000\u0000Materials and methods: The media was prepared by using commercially available MacConkey agar as the basal medium and incorporating it with 4% glycerol and four antimicrobials namely vancomycin, amphotericin B, gentamicin and colistin at a concentration of 2.5 mg/L, 1 mg/L, 5 mg/L and 10 mg/L respectively. The media was initially optimized for growth of B. pseudomallei by addition of 100 organisms/plate of B. pseudomallei and ATCC strains of Gram negative and Gram positive bacteria. Sterile and unsterile soils were spiked with graded concentration (1x106 to 1x101 CFU/gm of soil) of B. pseudomallei and other clinical and saprophytic Gram negative organisms and cultured on MacConkey, Ashdown and modified MacConkey media after enrichment in Ashdown broth. Growth of B. pseudomallei in the three media was compared. The newly devised media was termed as - Modified MacConkey agar for Burkholderia (MMB media).\u0000\u0000Results: Culture of supernatant from spiked sterile soil after enrichment showed equivalent isolation of B. pseudomallei on MMB and Ashdown’s media and there was 100% inhibition of Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa on MMB medium. Almost similar inhibition of Comamonas testosteroni, Aeromonas salmonicida and Burkholderia cepacia was observed on both MMB and Ashdown’s media. Culture of sterile soil seeded with different concentrations of P. aeruginosa showed no growth in MMB media. But there was growth of P. aeruginosa when sterile soil samples spiked with 1x106 to 1x103 CFU of P. aeruginosa were cultured in Ashdown media. When unsterile soil was seeded with graded concentration of B. pseudomallei, the colony count of this bacterium gradually declined in all three medium with decreased spiking concentrations. Growth of other soil organisms was less in MMB media compared to other two media.\u0000\u0000Conclusion: The newly devised MMB media is selective and easy to prepare for the detection of B. pseudomallei from soil.\u0000\u0000IMC J Med Sci. 2024; 18(1):011. DOI: https://doi.org/10.55010/imcjms.18.011\u0000\u0000*Correspondence:Md. Shariful Alam Jilani, Department of Microbiology, Ibrahim Medical College, 1/A Ibrahim Sarani, Segun Bagicha, Dhaka-1000, Bangladesh. Email: jilanimsa@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139620845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Species distribution and antimicrobial susceptibility pattern of coagulase-negative staphylococci isolated from clinical specimens at a tertiary care hospital","authors":"S. Tamboli, S. Tamboli","doi":"10.55010/imcjms.18.010","DOIUrl":"https://doi.org/10.55010/imcjms.18.010","url":null,"abstract":"Background and objectives: Coagulase-negative staphylococci (CoNS) are considered important causative agents of hospital acquired infection. These organisms are found in various clinical specimens from hospitalized patients. Present study was carried out to determine the species distribution and antimicrobial susceptibility pattern of CoNS isolated from clinical specimens at a tertiary care hospital. Materials and methods: CoNS isolated from various clinical samples were included in this study. The isolates were identified by colony morphology, Gram’s staining, catalase and coagulase tests. Further differentiation of species was performed by susceptibility to novobiocin, urease activity and ornithine decarboxylase test. Antibiotic susceptibility testing was performed according to the Clinical and Laboratory Standard Institute (CLSI) guidelines. Results: Total 108 isolates of CoNS were included and analysed. Out of 108 CoNS, S. epidermidis was the most common species (36.1%) followed by S. saprophyticus (23.1%), S. hemolyticus (17.6%), S. hominis (13%) and S. lugdunensis (10.2%). Most of the isolates showed resistance to penicillin, oxacillin, amoxycillin, erythromycin, ciprofloxacin and ofloxacin. All the isolates were sensitive to vancomycin. Conclusions: CoNS emerged as an important nosocomial pathogen and should not be neglected as contaminant. High rate of antimicrobial resistance warrants susceptibility testing prior to the treatment of CoNS. IMC J Med Sci. 2024; 18(1):010. DOI: https://doi.org/10.55010/imcjms.18.010 *Correspondence: Sabiha S Tamboli, Department of Microbiology, Parbhani Medical College and RP Hospital Research Institute, Pathri Road, Parbhani, Maharashtra, India. Email: sabihatamboli77@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"107 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139133557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}