Auris Nasus Larynx最新文献

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List of Reviewers (2025) 评审人员名单(2025年)
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-06-01 Epub Date: 2026-05-27 DOI: 10.1016/S0385-8146(26)00079-9
{"title":"List of Reviewers (2025)","authors":"","doi":"10.1016/S0385-8146(26)00079-9","DOIUrl":"10.1016/S0385-8146(26)00079-9","url":null,"abstract":"","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 3","pages":"Pages iii-v"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovations in paediatric cholesteatoma surgery 儿科胆脂瘤手术的创新
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-23 DOI: 10.1016/j.anl.2026.01.004
Adrian L James
{"title":"Innovations in paediatric cholesteatoma surgery","authors":"Adrian L James","doi":"10.1016/j.anl.2026.01.004","DOIUrl":"10.1016/j.anl.2026.01.004","url":null,"abstract":"<div><div>The management of children with cholesteatoma has advanced over the course of this century thanks to innovations in surgical instrumentation and other aspects of care. A narrative review giving a perspective on the contributions of advances such as dedicated equipment for endoscopic ear surgery including powered instrumentation and KTP laser, and other areas including CT and MRI imaging, is provided. These have helped raise the standard of care from achieving a “safe dry ear” potentially with a mastoid cavity, to less invasive approaches that can deliver a functionally and cosmetically normal ear in many cases. Areas in need of further innovative approaches persist in the control of residual and recurrent cholesteatoma and hearing loss. Surgeons are advised to be wary of over-reliance on the use of untested hypothetical mechanisms when considering the adoption of new technologies, such as Eustachian tube balloon dilatation. Improved standards for data collection, analysis and reporting will help ensure that efficacious and cost-effective innovations are adopted in future to further improve outcomes from the care of paediatric cholesteatoma.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 207-216"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current status of powered intracapsular tonsillectomy and adenoidectomy: A minimally invasive paradigm for pediatric obstructive sleep apnea surgery 动力囊内扁桃体切除术和腺样体切除术的现状:儿童阻塞性睡眠呼吸暂停手术的微创模式
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-29 DOI: 10.1016/j.anl.2026.01.007
Masamitsu Kono , Masao Noda , Manabu Komori , Nayu Yokoyama , Masakazu Hamamoto , Mari Shimada , Hirotaka Hara , Makoto Ito
{"title":"Current status of powered intracapsular tonsillectomy and adenoidectomy: A minimally invasive paradigm for pediatric obstructive sleep apnea surgery","authors":"Masamitsu Kono ,&nbsp;Masao Noda ,&nbsp;Manabu Komori ,&nbsp;Nayu Yokoyama ,&nbsp;Masakazu Hamamoto ,&nbsp;Mari Shimada ,&nbsp;Hirotaka Hara ,&nbsp;Makoto Ito","doi":"10.1016/j.anl.2026.01.007","DOIUrl":"10.1016/j.anl.2026.01.007","url":null,"abstract":"<div><h3>Objective</h3><div>To provide a practical, evidence-informed guide for clinicians on powered intracapsular tonsillectomy and adenoidectomy (PITA) in pediatric patients.</div></div><div><h3>Methods</h3><div>A narrative synthesis of contemporary studies, metaanalyses, and guideline statements on indications, techniques, devices, outcomes, complications, and implementation considerations for PITA was conducted. Device parameters and workflow tips are provided for practical reference.</div></div><div><h3>Results</h3><div>PITA consistently reduces secondary hemorrhage and pain, shortens the time to resumption of normal diet and activity and lowers the risk of readmission for dehydration relative to conventional extracapsular tonsillectomy. It also results in comparable resolution of obstructive symptoms in appropriately selected children. Endoscopic powered adenoidectomy enables complete, targeted resection under direct vision, protects the Eustachian tube and soft palate, and reduces revision rates relative to blind curettage. The trade-offs include a small but real risk of tonsillar regrowth (⁓2–6%) and a learning curve for powered/endoscopic techniques. The practical device settings (coblation ablation, 7–9; microdebrider, 600–800 rpm), endoscopic routes (transoral, 70°; transnasal, 0°), and safety pearls are provided.</div></div><div><h3>Conclusions</h3><div>PITA is a safe, efficient, and patient-centered treatment option for pediatric adenotonsillar disease, especially obstructive sleep apnea, when performed with endoscopic visualization and capsule preservation. Standardization of training, perioperative management including postoperative pain control and recovery course, and long-term outcome tracking will further promote its adoption in guidelines.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 217-229"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival analysis of initially inserted Kobayashi plugs in patulous Eustachian tube: A retrospective study of 297 ears 初步置入Kobayashi耳塞于扩张性耳咽管的生存分析:回顾性研究297耳
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-31 DOI: 10.1016/j.anl.2026.01.005
Takeshi Oshima , Marin Yoshida , Hidetoshi Oshima , Hideshi Shindo , Ryoji Hirai
{"title":"Survival analysis of initially inserted Kobayashi plugs in patulous Eustachian tube: A retrospective study of 297 ears","authors":"Takeshi Oshima ,&nbsp;Marin Yoshida ,&nbsp;Hidetoshi Oshima ,&nbsp;Hideshi Shindo ,&nbsp;Ryoji Hirai","doi":"10.1016/j.anl.2026.01.005","DOIUrl":"10.1016/j.anl.2026.01.005","url":null,"abstract":"<div><h3>Objectives</h3><div>Kobayashi Plug Surgery (KPS) is widely performed in Japan for refractory patulous Eustachian tube (PET). However, the duration of retention and long-term stability of the initially inserted plug have not been fully evaluated. Therefore, this study aimed to analyze plug retention (plug survival) and assess the validity of preoperative sonotubometry (ST) probe tone levels as an indicator for plug size selection.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted of 237 patients (297 ears) who underwent initial KPS between January 2020 and August 2025. Ears were categorized by initial plug size: group A (size 3), group B (size 4), and group C (size ≥5). Plug removal or replacement (upsizing or downsizing) was defined as an event, and survival was analyzed using the Kaplan–Meier method. Multivariate Cox regression and Weibull parametric models were applied to identify predictors of plug survival. Preoperative ST values were compared among groups and correlated with postoperative outcomes.</div></div><div><h3>Results</h3><div>At initial surgery, size 4 plugs were most frequently used (61%). During follow-up, 42 events occurred (14.1%). Kaplan–Meier analysis showed a mean survival time of 900.6 days and a 75% survival time of 1076 days, with no significant differences among groups (log-rank test, <em>p</em> = 0.61). Weibull analysis revealed a shape parameter (β) &lt;1, indicating high early postoperative risk followed by long-term stability. Cox regression showed no significant effects of plug size, age, or ST values on survival. Among the 181 ears treated with a size 4 plug, 96 were followed for more than one year without events, and 92 of these were classified as long-term favorable cases. Preoperative ST values differed among size groups but did not predict postoperative course, particularly in size 4 cases.</div></div><div><h3>Conclusion</h3><div>KPS demonstrated durable long-term effectiveness, with most plugs remaining stable beyond the early postoperative period. While ST levels guide initial size selection, long-term outcomes appear influenced by additional anatomical and clinical factors, underscoring the need for complementary diagnostics and individualized follow-up.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 234-238"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transoral surgery for hypopharyngeal and laryngeal cancers in Japan: Current status from a nationwide multicenter retrospective study 日本经口手术治疗下咽癌和喉癌:一项全国性多中心回顾性研究的现状
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-20 DOI: 10.1016/j.anl.2025.12.015
Koji Araki , Seiichi Yoshimoto , Takashi Fujii , Hiroki Mitani , Takashi Mukaigawa , Takahiro Asakage , Akihito Watanabe , Koichi Kano , Kenji Okami , Shigemichi Iwae , Takahiro Tsujikawa , Daisuke Sano , Masami Osaki , Naoki Nishio , Nobuhiro Hanai , Tomoyuki Arai , Mitsuhiko Nakahira , Yuki Saito , Kenzo Ohara , Takayuki Imai , Ken-ichi Nibu
{"title":"Transoral surgery for hypopharyngeal and laryngeal cancers in Japan: Current status from a nationwide multicenter retrospective study","authors":"Koji Araki ,&nbsp;Seiichi Yoshimoto ,&nbsp;Takashi Fujii ,&nbsp;Hiroki Mitani ,&nbsp;Takashi Mukaigawa ,&nbsp;Takahiro Asakage ,&nbsp;Akihito Watanabe ,&nbsp;Koichi Kano ,&nbsp;Kenji Okami ,&nbsp;Shigemichi Iwae ,&nbsp;Takahiro Tsujikawa ,&nbsp;Daisuke Sano ,&nbsp;Masami Osaki ,&nbsp;Naoki Nishio ,&nbsp;Nobuhiro Hanai ,&nbsp;Tomoyuki Arai ,&nbsp;Mitsuhiko Nakahira ,&nbsp;Yuki Saito ,&nbsp;Kenzo Ohara ,&nbsp;Takayuki Imai ,&nbsp;Ken-ichi Nibu","doi":"10.1016/j.anl.2025.12.015","DOIUrl":"10.1016/j.anl.2025.12.015","url":null,"abstract":"<div><h3>Objective</h3><div>In this nationwide retrospective study, we sought to evaluate the oncologic and functional outcomes and safety of transoral surgery (TOS) for hypopharyngeal and laryngeal squamous cell carcinomas in Japan and to clarify the appropriate indications for various TOS modalities.</div></div><div><h3>Methods</h3><div>Data were obtained from the Head and Neck Cancer Registry of Japan. Patients who underwent transoral or endoscopic resection between 2011 and 2016 were selected. Detailed clinical information was collected from 55 institutions using web-based case report forms. Surgical modalities analyzed included endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), endoscopic laryngopharyngeal surgery (ELPS), transoral laser microsurgery (TLM), and transoral videolaryngoscopic surgery (TOVS).</div></div><div><h3>Results</h3><div>In total, 1825 patients were included (hypopharyngeal cancer, 62.5 %; laryngeal cancer, 37.5 %). Most cases (77.5 %) were T1 or lower, and 90.8 % were Stage II or earlier. TLM is predominantly used for glottic cancers, ELPS/ESD for superficial hypopharyngeal lesions, and TOVS for more advanced tumors, reflecting distinct indications for each modality. The 5-year disease-specific survival (DSS), recurrence-free survival (RFS), and overall survival (OS) were 97.1 %, 84.3 %, and 85.4 %, respectively. The laryngeal preservation rate was 98.2 %. Tracheostomy was performed in 5.0 % of cases, mainly for airway protection; major complications, including pneumonia (2.4 %), hemorrhage (1.1 %), fistula formation (0.4 %), and vocal cord fixation (2.6 %), occurred in &lt;3 % of patients. Postoperative functional outcomes were favorable, with persistent dysphagia (Functional Outcome Swallowing Scale stage ≥ 3) in 1.6 % and tube feeding dependence in 1.8 %.</div></div><div><h3>Conclusion</h3><div>Non-robot-assisted TOS demonstrated excellent oncologic control and functional preservation of the larynx with low complication rates in early-stage hypopharyngeal and laryngeal cancers. Each surgical modality has distinct indications depending on the tumor site, depth of invasion, and institutional expertise. These findings support the use of TOS as a safe and effective treatment option for selected patients. Further procedural standardization and data accumulation are required to refine the indications and facilitate their broader adoption in clinical practice.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 188-200"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metachronous development of bilateral external auditory canal cancer 双侧外耳道癌的异时性发展
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-30 DOI: 10.1016/j.anl.2026.01.008
Hiroaki Masuda , Kazushi Fujiyama , Sanami Azuma , Toshiyuki Mukai , Anjin Mori , Sadahiro Kishishita , Sakiko Miura , Teppei Morikawa , Kazunari Nakao
{"title":"Metachronous development of bilateral external auditory canal cancer","authors":"Hiroaki Masuda ,&nbsp;Kazushi Fujiyama ,&nbsp;Sanami Azuma ,&nbsp;Toshiyuki Mukai ,&nbsp;Anjin Mori ,&nbsp;Sadahiro Kishishita ,&nbsp;Sakiko Miura ,&nbsp;Teppei Morikawa ,&nbsp;Kazunari Nakao","doi":"10.1016/j.anl.2026.01.008","DOIUrl":"10.1016/j.anl.2026.01.008","url":null,"abstract":"<div><div>Cancer originating from the external auditory canal (EAC) is rare, which precludes a clear understanding of the disease and its management approaches. We present an extremely rare case of bilateral auditory canal carcinoma that occurred heterochronously. Bilateral treatments resulted in good disease control and EAC structure preservation, which could accommodate various hearing aid options after cancer treatment. While disease control is the most crucial aspect to be considered when choosing a treatment of EAC cancer, one should also consider potential hearing ability in patients post-surgery, particularly in those with bilateral lesions, as it greatly influences the quality of life.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 230-233"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term outcomes of cochlear implants in patients over 65: Hearing thresholds remain stable, but speech perception declines with age 65岁以上患者人工耳蜗植入的长期结果:听力阈值保持稳定,但语言感知随着年龄的增长而下降。
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-19 DOI: 10.1016/j.anl.2026.01.003
Kanako Kondo , Hiroshi Yamazaki , Kayoko Mizuno , Seiko Kawae , Namie Iguchi , Naoe Mori , Yosuke Tona , Ken Kojima , Norio Yamamoto , Juichi Ito , Koichi Omori
{"title":"Long-term outcomes of cochlear implants in patients over 65: Hearing thresholds remain stable, but speech perception declines with age","authors":"Kanako Kondo ,&nbsp;Hiroshi Yamazaki ,&nbsp;Kayoko Mizuno ,&nbsp;Seiko Kawae ,&nbsp;Namie Iguchi ,&nbsp;Naoe Mori ,&nbsp;Yosuke Tona ,&nbsp;Ken Kojima ,&nbsp;Norio Yamamoto ,&nbsp;Juichi Ito ,&nbsp;Koichi Omori","doi":"10.1016/j.anl.2026.01.003","DOIUrl":"10.1016/j.anl.2026.01.003","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate long-term cochlear implant (CI) outcomes in elderly patients aged ≥65 years, with a particular focus on the impact of implantation age and chronological age at testing on auditory performance.</div></div><div><h3>Methods</h3><div>We conducted a retrospective study of 53 postlingually deafened adults aged ≥65 years at the time of outcome evaluation who underwent unilateral CI at our institute between 1987 and 2019. Patients were divided into two groups according to age at implantation: the Younger-elderly group (&lt;75 years; <em>n</em> = 36) and the Older-elderly group (≥75 years; <em>n</em> = 17). Postoperative aided thresholds and monosyllabic speech discrimination scores in quiet were collected annually up to 10 years postoperatively.</div></div><div><h3>Results</h3><div>CI-aided thresholds remained stable over 10 years after implantation and did not differ between groups (<em>p</em> = 0.40). In contrast, speech discrimination scores were significantly poorer in the Older-elderly group compared with the Younger-elderly group (<em>p</em> = 0.020). Regression analyses confirmed that chronological age at testing, but not age at implantation, was a significant predictor of speech outcomes (<em>p</em> &lt; 0.0001). Notably, patients aged ≥80 years exhibited mean CI-aided speech discrimination below 50 %.</div></div><div><h3>Conclusions</h3><div>CI effectively restored hearing thresholds in elderly patients, independent of implantation age. However, speech perception declined progressively with advancing test age, particularly in those ≥80 years, suggesting that central auditory and cognitive aging are the primary constraints on long-term outcomes. Candidacy criteria should therefore be applied cautiously in this age group, with thorough preoperative counseling to establish realistic expectations.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 174-179"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical factors for successful outcomes of endoscopic dacryocystrhinostomy 内镜下泪囊鼻腔造口术成功的关键因素
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-23 DOI: 10.1016/j.anl.2026.01.002
Hiroaki Masuda , Yasushi Ota , Atsushi Kuramochi , Ryosuke Yoshino , Hitomi Ikeda , Kotaro Ochi , Seikei Kan , Motoyoshi Kurosaki , Taro Takanami , Toshitake Tanaka , Munetaka Ushio
{"title":"Critical factors for successful outcomes of endoscopic dacryocystrhinostomy","authors":"Hiroaki Masuda ,&nbsp;Yasushi Ota ,&nbsp;Atsushi Kuramochi ,&nbsp;Ryosuke Yoshino ,&nbsp;Hitomi Ikeda ,&nbsp;Kotaro Ochi ,&nbsp;Seikei Kan ,&nbsp;Motoyoshi Kurosaki ,&nbsp;Taro Takanami ,&nbsp;Toshitake Tanaka ,&nbsp;Munetaka Ushio","doi":"10.1016/j.anl.2026.01.002","DOIUrl":"10.1016/j.anl.2026.01.002","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the factors that influence successful outcomes of endoscopic dacryocystorhinostomy (En-DCR), such as patency of the newly created ostium and lacrimal symptom improvement.</div></div><div><h3>Methods</h3><div>This retrospective, single-center study evaluated the medical records of individuals who underwent En-DCR at our institution between 2012 and 2023. A successful outcome was defined as both symptomatic improvement and patency of the newly created ostium at the last visit. The clinical factors influencing the outcome were analyzed using univariate and multivariate Cox proportional hazards regression analyses.</div></div><div><h3>Results</h3><div>This study evaluated 155 patients (age [mean ± SD] 69.2 ± 14.1 years; 113 women, 42 men, and 239 sides). Symptomatic improvement and a newly created ostium were observed in 181 sides (75.7 %). In multivariate analyses, the significant factors associated with successful En-DCR outcomes were placement of a silicone stent (hazard ratio [HR], 1.67; <em>p</em> = 0.0017), identification of a lacrimal puncta on the lateral wall of the lacrimal sac with an endoscope (HR, 1.96; <em>p</em> &lt; 0.001), and perioperative use of a lacrimal duct endoscope (HR, 2.03; <em>p</em> = 0.0011).</div></div><div><h3>Conclusions</h3><div>The critical factors influencing successful outcomes of En-DCR were the placement of a silicone stent, identification of the lacrimal puncta on the lateral wall of the lacrimal sac, and active use of a lacrimal duct endoscope. These findings may contribute to improving the success rate of En-DCR.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 201-206"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective descriptive study of unilateral subjective paroxysmal tinnitus: Clinical characteristics and exploratory findings on carbamazepine 单侧主观阵发性耳鸣的回顾性描述性研究:卡马西平的临床特点和探索性发现
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-17 DOI: 10.1016/j.anl.2026.01.001
Shuki Nishio , Kayoko Kabaya , Mariko Takahashi , Ayano Kojima , Ayano Imafuji , Takahisa Aoyama , Toshiya Minakata , Shinichi Esaki , Shinichi Iwasaki
{"title":"A retrospective descriptive study of unilateral subjective paroxysmal tinnitus: Clinical characteristics and exploratory findings on carbamazepine","authors":"Shuki Nishio ,&nbsp;Kayoko Kabaya ,&nbsp;Mariko Takahashi ,&nbsp;Ayano Kojima ,&nbsp;Ayano Imafuji ,&nbsp;Takahisa Aoyama ,&nbsp;Toshiya Minakata ,&nbsp;Shinichi Esaki ,&nbsp;Shinichi Iwasaki","doi":"10.1016/j.anl.2026.01.001","DOIUrl":"10.1016/j.anl.2026.01.001","url":null,"abstract":"<div><h3>Objective</h3><div>To descriptively characterize a retrospective case series of patients with unilateral subjective paroxysmal tinnitus, and to explore the potential therapeutic effects of carbamazepine as hypothesis-generating observations.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted of 829 patients who presented with tinnitus as their primary complaint. Patients diagnosed with unilateral subjective paroxysmal tinnitus were included, and those who received treatment with carbamazepine were analyzed in detail. Data regarding patient demographics, tinnitus characteristics, accompanying symptoms, magnetic resonance imaging (MRI) findings, and treatment responses to carbamazepine were analyzed.</div></div><div><h3>Results</h3><div>Forty-eight patients (5.8%) were identified as having paroxysmal tinnitus. Eight of these patients had causes unrelated to neurovascular compression. The remaining 40 patients (4.8%; 20 males, 20 females; mean age 63.5 years) presented with unilateral subjective tinnitus. Among them, 18 (2.2%) underwent treatment with carbamazepine. Among the carbamazepine-treated patients, vestibular symptoms were the most frequently reported accompanying symptom, noted in 14 patients (77.8%). MRI revealed arterial compression of the eighth cranial nerve in 2 patients (11.1%) and vascular-nerve contact in 10 patients (55.6%). Treatment with carbamazepine resulted in complete symptom resolution in 6 patients, partial improvement in 10, and no confirmed effect in 2, yielding an overall improvement rate of 88.9%.</div></div><div><h3>Conclusion</h3><div>In this retrospective case series, we described the heterogeneous clinical features of unilateral subjective paroxysmal tinnitus. While symptom improvement was observed among carbamazepine-treated cases regardless of MRI findings, the presence of an untreated subgroup, lack of a control group, and limitations of outcome measures warrant caution against causal claims of efficacy. Future studies with prospective comparative designs and validated quality-of-life endpoints are needed.</div></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"53 2","pages":"Pages 165-173"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of structured patient-to-patient communication on fear of cancer recurrence in total laryngectomy patients: A randomized controlled trial 结构化的患者间沟通对全喉切除术患者癌症复发恐惧的影响:一项随机对照试验。
IF 1.5 4区 医学
Auris Nasus Larynx Pub Date : 2026-04-01 Epub Date: 2026-01-20 DOI: 10.1016/j.anl.2026.01.006
Yiyao Liu , Wenjing Li , Chen He , Licheng Xu , Yujian Teng , Lei Zhang , Ying Zhao , Jiarui Zhang , Linli Tian , Mei Yin
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