Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology最新文献

Commentary on toxicological and pro-arrhythmic risks of high-caffeine beverages. 评论高咖啡因饮料的毒理学和诱发心律失常的风险。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3936

Anna Vittoria Mattioli

引用次数: 0

From wetlands to landfills: white stork (Ciconia ciconia L., 1758) as a reliable bioindicator of ecosystem health. 从湿地到垃圾填埋场：白鹳（Ciconia Ciconia L., 1758）作为生态系统健康的可靠生物指标。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3958

Dora Bjedov, Alma Mikuška, Mirna Velki

{"title":"From wetlands to landfills: white stork (Ciconia ciconia L., 1758) as a reliable bioindicator of ecosystem health.","authors":"Dora Bjedov, Alma Mikuška, Mirna Velki","doi":"10.2478/aiht-2025-76-3958","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3958","url":null,"abstract":"White storks (Ciconia ciconia L., 1758) and their nestlings have emerged as valuable bioindicators of environmental pollution, particularly in ecosystems affected by human activities. This review explores the role of white storks in biomonitoring, focusing on the use of biomarkers and pollutant analysis to understand the physiological consequences of environmental stressors. Key biomarkers, such as oxidative stress markers, immune responses, and hormonal alterations provide insight into the effects of pollutants like heavy metals, pesticides, and other toxic compounds. The biomarkers are typically measured in matrices such as blood, feathers, eggs, and tissues, each offering unique advantages in assessing pollutant exposure. However, ethical concerns regarding wildlife monitoring and the potential harm caused by invasive sampling techniques call for non-invasive methods. Future research should explore novel non-invasive techniques and employ long-term monitoring programmes to understand the cumulative effects of pollution. Despite challenges such as biological variability and environmental factors, white storks remain reliable indicators of ecological change and pollutant burden, providing critical data that can guide pollution management policies, inform conservation strategies, and protect both wildlife and human health from current environmental threats.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"1-15"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occupational injuries and associated factors among cement factory workers in the city of Chlef, Algeria. 阿尔及利亚克利夫市水泥厂工人的职业伤害及相关因素。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3929

Said Djaballah, Fatima Merouchi, Nahla Mosetfai, Abdelhak Belahcene, Abdelmoumene Hechifa

{"title":"Occupational injuries and associated factors among cement factory workers in the city of Chlef, Algeria.","authors":"Said Djaballah, Fatima Merouchi, Nahla Mosetfai, Abdelhak Belahcene, Abdelmoumene Hechifa","doi":"10.2478/aiht-2025-76-3929","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3929","url":null,"abstract":"Even though accident rates in cement industry tend to be higher than in other manufacturing sectors and significantly contribute to overall worker disabilities and illnesses, they are reported poorly. The aim of our cross-sectional study was to assess occupational injuries and associated factors among cement factory workers in the city of Chlef, Algeria using a questionnaire distributed to 200 workers who agreed to participate in the study. We found that 53 participants working in a cement mill (26.5 %) reported having 64 occupational injuries, which mostly affected their hands (44 %) and feet (38 %). Machinery accounted for 39 % of all injuries, while falls accounted for 27 %. Multivariate analysis revealed that work in a quarry, lower education, and longer working years were significantly associated with higher injury rates. Long-term exposure to risks, rather than just inexperience, highlights the need for a reassessment of ongoing safety training and monitoring for experienced workers. Future research should also explore how organisational factors such as workload, work hours, job stress, and the state of machinery contribute to the risk of occupational injuries. An approach combining quantitative and qualitative data from workers and management across cement plants in Algeria and the region could provide an even more comprehensive view of occupational risks and safety practices and help contextualise these findings for policy improvements.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"31-36"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge and perceptions of ionising radiation among Croatian general practitioners: is there cause for concern? 克罗地亚全科医生对电离辐射的认识和认知：是否有值得关注的理由？

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3916

Andro Matković, Thomas Ferenc, Lucija Dimjašević, Martin Drinković, Marko Marelić, Branka R Matković, Vinko Vidjak, Jelena Popić

{"title":"Knowledge and perceptions of ionising radiation among Croatian general practitioners: is there cause for concern?","authors":"Andro Matković, Thomas Ferenc, Lucija Dimjašević, Martin Drinković, Marko Marelić, Branka R Matković, Vinko Vidjak, Jelena Popić","doi":"10.2478/aiht-2025-76-3916","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3916","url":null,"abstract":"Recent data suggest that general practitioners (GPs) are insufficiently familiar with health risks associated with ionising radiation and radiation doses. The aim of our cross-sectional study was therefore to see if this holds true for Croatian GPs. To do that, we distributed a questionnaire about ionising radiation and doses used in various radiological procedures by email or by handing it out to participants at a national GP conference. We received responses from 120 participating GPs. Most were women (83.1 %), and the mean participant age was 44.2 years (range 26-65) with mean practice of 17.1 years (range 1-40). Most participants (97 %) believed patients should be informed about the procedures they were referred to. All respondents knew that radiological procedures irradiate the patient's body, but not everyone agreed that they could be harmful. Less than half (47 %) thought that exposure to a single irradiation dose was enough to increase cancer risk. Most participants (89.2 %) identified X-ray scans as the largest irradiation source, whereas three GPs replied that computed tomography (CT) and conventional X-ray procedures did not involve radiation. Some respondents did not know if ultrasound involved ionising radiation. Although most GPs were women, only 21.7 % correctly identified the radiation dose in mammography. Our findings confirm inadequate GPs' knowledge of radiation exposures and call for better training programmes as part of continuing professional development.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"24-30"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demographic and clinical profile of young adult emergency ward patients in Serbia who attempted suicide by poisoning during the COVID-19 pandemic: a retrospective cohort study. 2019冠状病毒病大流行期间塞尔维亚急诊病房年轻成人投毒自杀的人口学和临床特征：一项回顾性队列研究

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3933

Maja Petrović, Ana Simić, Katarina Simić, Gordana Vuković Ercegović, Nataša Perković Vukčević, Slavica Vučinić, Zvezdana Stojanović

{"title":"Demographic and clinical profile of young adult emergency ward patients in Serbia who attempted suicide by poisoning during the COVID-19 pandemic: a retrospective cohort study.","authors":"Maja Petrović, Ana Simić, Katarina Simić, Gordana Vuković Ercegović, Nataša Perković Vukčević, Slavica Vučinić, Zvezdana Stojanović","doi":"10.2478/aiht-2025-76-3933","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3933","url":null,"abstract":"Suicide is the fourth leading cause of death in young adults worldwide. Given the vulnerability of this population, the aim of our retrospective cohort study was to examine the demographic and clinical profile of 193 young adult emergency ward patients at the Clinic for Emergency and Clinical Toxicology of the National Poison Control Centre (NPCC), Military Medical Academy (MMA) in Belgrade, Serbia who attempted suicide by poisoning in 2020-2023. More than half suffered from a mental disorder, and poisoning mainly involved marketed prescription drugs (most often benzodiazepines). Women attempted suicide by poisoning more often and had a history of previous attempts, while men had more ensuing complications and were older. Current mental disorders and current psychopharmacotherapy positively correlated with the number of suicide attempts by poisoning and with the history of previous poisoning with prescription drugs. The number of suicide attempts by poisoning also correlated positively with self-harm. Our results suggest that the experience of the pandemic has highlighted the need to strengthen mental healthcare. Developing the resilience of young people, establishing help centres, and improving public awareness of this important issue could help reduce the incidence of suicide attempts in young adult population.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"37-43"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effects of chlorogenic acid against glyphosate-induced organ and blood toxicity in Wistar rats. 绿原酸对草甘膦致Wistar大鼠器官和血液毒性的保护作用。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3955

Ruhi Türkmen, Yavuz Osman Birdane, Orkun Atik, Hasan Huseyin Demirel, Durmus Fatih Baser

{"title":"Protective effects of chlorogenic acid against glyphosate-induced organ and blood toxicity in Wistar rats.","authors":"Ruhi Türkmen, Yavuz Osman Birdane, Orkun Atik, Hasan Huseyin Demirel, Durmus Fatih Baser","doi":"10.2478/aiht-2025-76-3955","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3955","url":null,"abstract":"Glyphosate, a widely used herbicide against broadleaf weeds and grasses, has been associated with various harmful effects. Our study examines the efficacy of chlorogenic acid (CGA) in alleviating the toxicity of a glyphosate-based herbicide (GBH) in 42 Wistar rats across six groups of seven animals receiving either no treatment (control), CGA alone (50 mg/kg), GBH alone (800 mg/kg), or their combinations varying three CGA doses (12.5, 25, or 50 mg/kg) (CGA12.5+GBH, CGA25+GBH, and CGA50+GBH, respectively) by oral gavage over 49 days in a row. At the end of the experiment, samples of blood, brain, heart, liver, and kidney tissues were collected and analysed for oxidative stress indicators (MDA, GSH, SOD, CAT), oxidative DNA damage (8-OHdG), liver and kidney function markers (AST, ALT, ALP, urea, and creatinine) as well as for histopathological changes. As expected, GBH increased AST ALT, ALP, urea, creatinine, 8-OHdG, and MDA levels, and lowered GSH levels and SOD and CAT activities, leaving histopathological changes in the brain, heart, liver, and kidney tissues. CGA dose-dependently improved biochemical and oxidative stress parameters and reversed histopathological changes in GBH-treated albino rats. Our findings consistently confirm the potential of CGA as a promising natural agent against the adverse health effects associated with exposure to glyphosate. Future research should focus on long-term glyphosate exposure and CGA treatment using molecular methods and on the signalling pathways associated with oxidative stress.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"44-52"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiation processing for public health: Croatia's contribution to food safety and sterilisation practices. 辐射加工促进公共卫生：克罗地亚对食品安全和消毒做法的贡献。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3960

Ivana Tartaro Bujak, Željka Knežević, Marija Majer

引用次数: 0

Morphine and codeine in racing horse feed: is there reason for concern? 赛马饲料中的吗啡和可待因：有理由担心吗？

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3888

Irena Brčić Karačonji, Tea Jelača, Andreja Jurič, Ana Lucić Vrdoljak

{"title":"Morphine and codeine in racing horse feed: is there reason for concern?","authors":"Irena Brčić Karačonji, Tea Jelača, Andreja Jurič, Ana Lucić Vrdoljak","doi":"10.2478/aiht-2025-76-3888","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3888","url":null,"abstract":"Opiates such as morphine and codeine are substances often misused to improve the performance of racing horses during competitions and are therefore on the International Federation for Equestrian Sports' list of prohibited substances. However, a positive antidoping test may be due to the consumption of feed (mainly lucerne or oats) contaminated by opium poppy containing the alkaloids morphine and codeine. In order to determine whether a positive antidoping test is the result of an intentional abuse of opiates or consumption of feed contaminated by poppies, we optimised conditions for the extraction of morphine and codeine from dehydrated lucerne and developed and validated a gas chromatography-mass spectrometry (GC-MS) method for the simultaneous determination of both analytes. The most efficient extraction of morphine and codeine from dehydrated lucerne was achieved using a citrate buffer pH4 followed by solid phase extraction. The method showed satisfactory linearity (R2>0.9980) in the tested concentration range (85-1600 ng/g), as well as good precision (RSD<4 %), accuracy (>95 %), and sensitivity (limit of detection 22 and 25 ng/g for morphine and codeine, respectively). The proposed method was used for analysing a sample of dehydrated lucerne having measurable content of morphine (1510 ng/g) and codeine (327 ng/g) that can cause positive results of opiate blood or urine testing up to 4 hours after feeding the horse with less than 500 g of dehydrated lucerne. The use of this analytical method should enable the exclusion of horse feed as the cause of positive antidoping tests.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"60-66"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oestrogenic and androgenic activity of oxybenzone and methylparaben in vitro. 氧苯酮和对羟基苯甲酸甲酯体外雌激素和雄激素活性的研究。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3964

Nikolina Peranić, Lucija Božičević, Ivana Vinković Vrček

引用次数: 0

Multiple cystic echinococcosis: the importance of preventive examination and collaborative treatment. 多发性囊性包虫病：预防检查与协同治疗的重要性。

IF 1.7 4区医学

Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology Pub Date : 2025-03-31 eCollection Date: 2025-03-01 DOI: 10.2478/aiht-2025-76-3972

Diana Bućan, Marko Neveščanin, Ivan Bućan

{"title":"Multiple cystic echinococcosis: the importance of preventive examination and collaborative treatment.","authors":"Diana Bućan, Marko Neveščanin, Ivan Bućan","doi":"10.2478/aiht-2025-76-3972","DOIUrl":"https://doi.org/10.2478/aiht-2025-76-3972","url":null,"abstract":"This case report presents a 43-year-old worker (welder in the locksmith trade) from Bosnia and Herzegovina who was diagnosed with advanced hydatidosis during a preventive medical examination. The patient had a history of frequent close contact with dogs at home and at work and reported a long-standing sensation of heaviness in the left side of his abdomen. As part of his routine occupational health examination, he had a complete laboratory testing, abdominal ultrasound, multislice computed tomography (MSCT), and a consultation with an infectious disease specialist and abdominal surgeon. Imaging revealed multiple cystic formations in the left hemiabdomen and a cyst in segment VIII of the liver, confirming the diagnosis of multivisceral echinococcosis. The patient was promptly treated with preoperative (and postoperative) albendazole to reduce the cyst size and prevent complications. This case highlights the critical role of ultrasound in the diagnosis of hydatidosis, especially in an occupational medicine context. As part of preventive screening, ultrasound is a valuable tool for the early detection of echinococcosis in workers in high-risk environments. Early diagnosis allows for timely intervention, reducing the risk of disease progression to an advanced stage. This case underscores the importance of implementing effective epidemiological strategies, including regular screenings and awareness campaigns, in order to control the spread of echinococcosis in endemic regions.","PeriodicalId":55462,"journal":{"name":"Arhiv Za Higijenu Rada I Toksikologiju-Archives of Industrial Hygiene and Toxicology","volume":"76 1","pages":"67-70"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0