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Structure, function, and mechanism of the TNFAIP8 (TIPE) family of proteins in cancer and inflammation TNFAIP8 (TIPE)蛋白家族在癌症和炎症中的结构、功能和机制
4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.030233
ZIPENG LIN, CHUXI TANG, LE KANG, GUANXI LAI, SHIWEN LIU, YIXIANG WU, HUIQUN TIAN, SONG LIU
{"title":"Structure, function, and mechanism of the TNFAIP8 (TIPE) family of proteins in cancer and inflammation","authors":"ZIPENG LIN, CHUXI TANG, LE KANG, GUANXI LAI, SHIWEN LIU, YIXIANG WU, HUIQUN TIAN, SONG LIU","doi":"10.32604/biocell.2023.030233","DOIUrl":"https://doi.org/10.32604/biocell.2023.030233","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135557423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent progress in microbial cell surface display systems and their application on biosensors 微生物细胞表面显示系统及其在生物传感器上的应用研究进展
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.028035
Haiying Chen, Yuqing Wu, Baojian Huang, Lei Han
{"title":"Recent progress in microbial cell surface display systems and their application on biosensors","authors":"Haiying Chen, Yuqing Wu, Baojian Huang, Lei Han","doi":"10.32604/biocell.2023.028035","DOIUrl":"https://doi.org/10.32604/biocell.2023.028035","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"74 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74566854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting the “undruggable” cancer driver genes: Ras, myc, and tp53 靶向“无法治疗”的癌症驱动基因:Ras, myc和tp53
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.028790
Xingbo Wu, Dan Pan, Shouyi Tang, Yingqiang Shen
{"title":"Targeting the “undruggable” cancer driver genes: Ras, myc, and tp53","authors":"Xingbo Wu, Dan Pan, Shouyi Tang, Yingqiang Shen","doi":"10.32604/biocell.2023.028790","DOIUrl":"https://doi.org/10.32604/biocell.2023.028790","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"32 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74991655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DNA polymerase θ (POLQ): A druggable DNA polymerase for homologous recombination-deficient cancer cells DNA聚合酶θ (POLQ):一种可用于同源重组缺陷癌细胞的药物性DNA聚合酶
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.025747
Meran Keshawa Ediriweera
{"title":"DNA polymerase θ (POLQ): A druggable DNA polymerase for homologous recombination-deficient cancer cells","authors":"Meran Keshawa Ediriweera","doi":"10.32604/biocell.2023.025747","DOIUrl":"https://doi.org/10.32604/biocell.2023.025747","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"73 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86401019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of natural products combination on MCF-7 cells exceeds tamoxifen therapeutic dose effects in vitro 在体外实验中，天然产物联合使用对MCF-7细胞的影响超过了他莫昔芬的治疗剂量效应
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.026556
Zeinab M. Klaab, Aziza M Hassan, Jawaher J Albaqami, Faizah A. ALMALKI
{"title":"The effect of natural products combination on MCF-7 cells exceeds tamoxifen therapeutic dose effects in vitro","authors":"Zeinab M. Klaab, Aziza M Hassan, Jawaher J Albaqami, Faizah A. ALMALKI","doi":"10.32604/biocell.2023.026556","DOIUrl":"https://doi.org/10.32604/biocell.2023.026556","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"18 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85345776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Network biology: A promising approach for drug target identification against neurodevelopmental disorders 网络生物学:神经发育障碍药物靶点鉴定的一种有前途的方法
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.029624
Wayez Naqvi, Ananya Singh, Prekshi Garg, P. Srivastava
{"title":"Network biology: A promising approach for drug target identification against neurodevelopmental disorders","authors":"Wayez Naqvi, Ananya Singh, Prekshi Garg, P. Srivastava","doi":"10.32604/biocell.2023.029624","DOIUrl":"https://doi.org/10.32604/biocell.2023.029624","url":null,"abstract":"Biological entities are involved in complicated and complex connections; hence, discovering biological information using network biology ideas is critical. In the past few years, network biology has emerged as an integrative and systems-level approach for understanding and interpreting these complex interactions. Biological network analysis is one method for reducing enormous data sets to clinically useful knowledge for disease diagnosis, prognosis, and treatment. The network of biological entities can help us predict drug targets for several diseases. The drug targets identified through the systems biology approach help in targeting the essential biological pathways that contribute to the progression and development of the disease. The novel strategical approach of system biologyassisted pharmacology coupled with computer-aided drug discovery (CADD) can help drugs fight multifactorial diseases efficiently. In the present review, we have summarized the role and application of network biology for not only unfolding the mechanism of complex neurodevelopmental disorders but also identifying important drug targets for diseases like ADHD, Autism, Epilepsy, and Intellectual Disability. Systems biology has emerged as a promising approach to identifying drug targets and aiming for targeted drug discovery for the precise treatment of neurodevelopmental disorders.","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"5 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75555611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AKT regulates IL-1β-induced proliferation and activation of hepatic stellate cells AKT调节il -1β诱导的肝星状细胞的增殖和活化
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.025365
Yongdae Yoon, Soonjae Hwang, Fatema Tuj Saima, Moon YOUNG KIM, Soon KOO BAIK, Young WOO EOM
{"title":"AKT regulates IL-1β-induced proliferation and activation of hepatic stellate cells","authors":"Yongdae Yoon, Soonjae Hwang, Fatema Tuj Saima, Moon YOUNG KIM, Soon KOO BAIK, Young WOO EOM","doi":"10.32604/biocell.2023.025365","DOIUrl":"https://doi.org/10.32604/biocell.2023.025365","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"62 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86735970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic application of mesenchymal stem cells-derived extracellular vesicles in colorectal cancer 间充质干细胞来源的细胞外囊泡在结直肠癌治疗中的应用
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.025603
M. Nemati, Yousef Rasmi, J. Rezaie
{"title":"Therapeutic application of mesenchymal stem cells-derived extracellular vesicles in colorectal cancer","authors":"M. Nemati, Yousef Rasmi, J. Rezaie","doi":"10.32604/biocell.2023.025603","DOIUrl":"https://doi.org/10.32604/biocell.2023.025603","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"29 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78580120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatitis B virus X protein-mediated upregulation of miR-221 activates the CXCL12-CXCR4 axis to promote NKT cells in HBV-related hepatocellular carcinoma 乙型肝炎病毒X蛋白介导的miR-221上调激活CXCL12-CXCR4轴，促进hbv相关肝细胞癌中的NKT细胞
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.027205
Yue Cao, Lin Hu, Yishu Tang
{"title":"Hepatitis B virus X protein-mediated upregulation of miR-221 activates the CXCL12-CXCR4 axis to promote NKT cells in HBV-related hepatocellular carcinoma","authors":"Yue Cao, Lin Hu, Yishu Tang","doi":"10.32604/biocell.2023.027205","DOIUrl":"https://doi.org/10.32604/biocell.2023.027205","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"6 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90899701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-fibrotic and anti-inflammatory effect of mesenchymal stromal cell-derived extracellular vesicles in chronic kidney disease 间充质间质细胞来源的细胞外囊泡在慢性肾病中的抗纤维化和抗炎作用
IF 1.2 4区 生物学
Biocell Pub Date : 2023-01-01 DOI: 10.32604/biocell.2023.028121
Giulia Chiabotto, S. Bruno
{"title":"Anti-fibrotic and anti-inflammatory effect of mesenchymal stromal cell-derived extracellular vesicles in chronic kidney disease","authors":"Giulia Chiabotto, S. Bruno","doi":"10.32604/biocell.2023.028121","DOIUrl":"https://doi.org/10.32604/biocell.2023.028121","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"2 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90270092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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