Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie最新文献

{"title":"What Sustains the Journal: Editorial Reflections on Peer Review and Progress of the <i>Canadian Journal of Psychiatry</i>.","authors":"Lakshmi N Yatham, Ayal Schaffer","doi":"10.1177/07067437261423045","DOIUrl":"10.1177/07067437261423045","url":null,"abstract":"","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"343-345"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12971511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Cross-Sectional Associations Between Cannabis Use and Anxiety, Depression, and Suicidality in a Nationally Representative Sample of Canadians From 2012 to 2022: Évolution des relations transversales entre la consommation de cannabis et la dépression, l'anxiété et les idées suicidaires au sein d'un échantillon représentatif de Canadiens à l'échelle nationale, de 2012 à 2022.","authors":"Jillian Halladay, Chris Ji, Katholiki Georgiades, André McDonald, Matthew Sunderland, Tim Slade, Cath Chapman, James MacKillop","doi":"10.1177/07067437261420701","DOIUrl":"10.1177/07067437261420701","url":null,"abstract":"<p><p>ObjectiveAs epidemiological patterns of cannabis use and internalizing problems evolve globally, it is critical to reassess their associations-particularly in the post-legalization and post-pandemic context<b>.</b>MethodsParticipants were assessed in the 2012 Canadian Community Health Survey's Mental Health Component (CCHS-MH; <i>n</i> = 25,113) and 2022 Mental Health and Access to Care Survey (MHACS; <i>n</i> = 9,861), two nationally representative cross-sectional epidemiologic surveys of Canadians aged 15+. Robust Poisson Regression analyses examined associations between frequency of cannabis use and past 12-month generalized anxiety disorder (GAD), major depressive episode (MDE), and suicidality assessed using the World Health Organization Composite International Diagnostic Interview.ResultsBetween 2012 and 2022, the prevalence of GAD, MDE, and cannabis use (any and 2+/week) approximately doubled, while suicidality remained unchanged in the full sample but increased by 44% among youth. Across all models, cannabis frequency was consistently associated with a higher prevalence of GAD, MDE, and suicidality in a frequency-dependent fashion. Additive interactions between year and cannabis on each of the outcomes demonstrated stronger associations in 2022 versus 2012. For example, from 2012 to 2022, those using cannabis 2+/week (relative to no use) had a: (1) prevalence ratio (PR) for GAD of 2.3 (95% CI, 1.6-3.4) increase to 4.5 (3.8-5.2); (2) PR for MDE of 3.0 (2.3-3.9) increase to 5.2 (4.6-5.7); and (3) PR for suicidality of 3.0 (2.1-4.0) increase to 5.4 (4.7-6.1). Select moderation effects indicated associations between cannabis and MDE or suicidality strengthened more among youth (15-24 vs. 25+), and associations with GAD strengthened more among females.ConclusionsCannabis use was consistently related to a higher prevalence of internalizing problems, and these associations strengthened between 2012 and 2022. Given continued escalations in co-occurring cannabis use and internalizing problems, greater investment in early identification, intervention, and access to integrated substance use and mental health treatment is needed.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"383-395"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12945739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147291909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pragmatic Evaluation of an Urban-Based Emergency Telepsychiatry Program in Winnipeg, Canada: Évaluation pragmatique d'un programme urbain de télépsychiatrie d'urgence à Winnipeg, au Canada.","authors":"Jennifer M Hensel, Kevin J Friesen, Eefa Khan, Jitender Sareen, James M Bolton","doi":"10.1177/07067437261428835","DOIUrl":"10.1177/07067437261428835","url":null,"abstract":"<p><p>ObjectiveEmergency telepsychiatry programs have demonstrated value in urban settings but remain under-studied in terms of their impact on access and flow. This pragmatic study assessed patients seen by a novel emergency telepsychiatry service over 4 years in Winnipeg, Canada, during a time of rapid system change. Outcomes were compared to a cohort of hospitalized individuals who received an in-person emergency psychiatric assessment during the same time period.MethodTelepsychiatry assessments between January 1, 2018 and December 31, 2021 were logged and linked with administrative data to examine variables pre-consult, during the episode of care, and post-consult. For individuals admitted to hospital following the telepsychiatry assessment, we generated a comparison group of individuals admitted following in-person consult at the eligible sites. Emergency Department length of stay (ED LOS), hospital admission diagnosis and days in hospital were compared between groups.ResultsA total of 558 telepsychiatry consults were logged during the study period of which 520 (93.1%) were successfully linked to administrative data. The volume of telepsychiatry consults decreased over time in parallel with changes to in-person staffing and referring facility designation. Rate of admission following the telepsychiatry assessment was 50% or lower across all years. For comparison, 222 telepsychiatry and 756 in-person visits resulting in psychiatric hospital admission were identified. Telepsychiatry-triggered hospitalizations were more likely to be for individuals presenting during daytime (0801-1700 h) and with mood/suicidal chief complaints at triage (<i>P</i> < 0.001). No differences in overall ED LOS, admission diagnosis, or days in hospital were observed.ConclusionTelepsychiatry services in urban ED settings have the potential to offer access to timely consults in the absence of in-person care. This model can optimize resources and offer flexibility in the face of rapidly evolving and unanticipated health system changes.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"396-405"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12982145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Dynamic Postural Control in Remitted Bipolar I Disorder: A Computerized Dynamic Posturography Study: Contrôle postural dynamique chez les personnes atteintes d'un trouble bipolaire de type I en rémission : Étude de posturographie dynamique informatisée\".","authors":"","doi":"10.1177/07067437261446372","DOIUrl":"10.1177/07067437261446372","url":null,"abstract":"","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261446372"},"PeriodicalIF":3.8,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Abstract Screening Algorithm Using Delphi-Inspired Large Language Model Consensus for Systematic Reviews in Psychiatry: Nouvel algorithme de sélection des résumés utilisant un consensus issu d'un grand modèle de langage inspiré de la méthode Delphi pour les revues systématiques en psychiatrie.","authors":"Mirkamal Tolend, Ramzi Halabi, Kousai Ghaouari, Yvonne C Y Lau, Martin Alda, Arend Hintze, Benoit H Mulsant, Abigail Ortiz","doi":"10.1177/07067437261445767","DOIUrl":"10.1177/07067437261445767","url":null,"abstract":"<p><p>BackgroundLarge language models (LLMs) may reduce the burden associated with performing systematic reviews by prescreening abstracts from a literature search for eligibility for inclusion in full-text review.MethodsWe developed an iterative, LLM-based workflow for screening abstracts: after manual specification of eligibility criteria and seed examples, an ensemble of five LLMs deliberates through a Delphi process to classify a batch of abstracts; these labels are used to train a logistic regression model that ranks the remaining abstracts and identifies a new batch of abstracts for LLM escalation until all abstracts are labelled by the LLM or probability thresholds. We tested our workflow on abstracts screened in three published systematic reviews in psychiatry. Our primary endpoint was the recall metric, and secondary endpoint was the work saved over sampling at 95% recall metric (WSS@95%).ResultsIn a dataset on autism biomarkers, 1,655 (35%) of 4,745 retrieved abstracts were judged to be relevant by the original authors. The Delphi-LLM workflow correctly identified 1,605 (97.0%) of these 1,655 abstracts (precision = 54.2%, WSS@95% = 38.1%). The performance metrics were better than non-LLM approaches (recall ≤ 91%, WSS@95 ≤ 26%), and, overall, balanced these metrics optimally compared to single-LLM agents (recall = 84.9-99.9%, WSS@95% = 16.7-39.8%). The recall and work saved metrics were similarly reliable and among the top in two low-prevalence datasets on an attention-deficit hyperactivity disorder treatment review (10% of 2,891 relevant) and a posttraumatic stress disorder trajectory review (7% of 4,453 relevant). For these two datasets, recall was 100.0% and 96.4%, and the WSS@95% was 17.3% and 18.5%, respectively.ConclusionsWe presented the design and validation of a novel abstract screening workflow that centres around a Delphi-style aggregation process to harness the strengths of five open-source LLMs that can be run on consumer-level workstations. This multi-LLM workflow showed acceptable and reliable performance for use as an automated prescreening method to facilitate systematic reviews.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261445767"},"PeriodicalIF":3.8,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13133002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Faecal Transplantation for Bipolar Disorder.","authors":"Gordon Parker","doi":"10.1177/07067437261445768","DOIUrl":"10.1177/07067437261445768","url":null,"abstract":"","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261445768"},"PeriodicalIF":3.8,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Risk Human-AI Engagement: Clinical Assessment and Management Considerations.","authors":"Lena Palaniyappan, Vincent Paquin, Etienne Barou-Laforie","doi":"10.1177/07067437261445770","DOIUrl":"https://doi.org/10.1177/07067437261445770","url":null,"abstract":"","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261445770"},"PeriodicalIF":3.8,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Depression and Quality of Life in Children and Adolescents: A Systematic Review: Lien entre dépression et qualité de vie chez les enfants et les adolescents : Une revue systématique.","authors":"Parker L Grant, Jordan F Drotsky, Abby L Goldstein, Tony P George","doi":"10.1177/07067437261442375","DOIUrl":"https://doi.org/10.1177/07067437261442375","url":null,"abstract":"<p><p>ObjectiveMajor depressive disorder is a debilitating mental health issue that frequently emerges during childhood or adolescence. Although prior research has established the burden of depressive symptoms in young people, less is known about how depression affects quality of life (QoL), a multidimensional construct encompassing emotional, physical and social functioning. This systematic review aimed to systematically evaluate the association between depression and QoL in children and adolescents, with particular attention to domain-specific and informant effects.MethodFollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, MEDLINE, Embase and PsycINFO were searched from inception to July 31, 2025, and reference lists of included studies were searched. Eligible studies included English-language, peer-reviewed, observational studies assessing depression and QoL using validated measures in children and adolescents (defined as samples with all participants <18 years or with a mean age <18). Studies focused on general well-being and samples with comorbidities were excluded. Risk of bias was assessed using the appropriate Joanna Briggs Institute Critical Appraisal Checklists. A structured narrative synthesis was conducted, grouping studies by comparison type (e.g., depressed vs. nondepressed groups, severity-QoL associations, domain-specific outcomes and informant differences).ResultsTwenty-seven studies (<i>N</i> = 28,738) met inclusion criteria. Across clinical and community samples, depression was consistently associated with lower QoL, particularly within emotional domains. Several studies also highlighted discrepancies between child and parent QoL assessments.ConclusionsEvidence was limited by heterogeneity in measurement tools, inconsistent adjustment for confounders, item overlap between constructs and a scarcity of longitudinal designs. Nonetheless, findings underscore the significant impact of depression on children's and adolescents' lives beyond symptom severity alone. This systematic review highlights the importance of assessing QoL alongside depression symptoms to inform comprehensive, person-centred approaches to child and adolescent mental health care. Future research should prioritize longitudinal designs and the examination of mediators and moderators that shape the depression-QoL relationship.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261442375"},"PeriodicalIF":3.8,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Intersection of Autism and Gender Diversity in the Canadian Clinical Context: Characterizing a Sample of Adults Referred to Canada's Largest Publicly Funded Adult Gender-Care Service: Intersection de l'autisme et de la diversité des identités de genre dans le contexte clinique canadien : Caractérisation d'un échantillon d'adultes orientés vers le plus grand service de soins en matière d'identité de genre destinés aux adultes financé par le secteur public au Canada.","authors":"Molly Isabel Pascoe, Jacqueline Vincent, Meng-Chuan Lai, Pushpal Desarkar, Nina Vitopoulos, Yona Lunsky, Kinnon Ross MacKinnon, June Sing Hong Lam","doi":"10.1177/07067437261442432","DOIUrl":"https://doi.org/10.1177/07067437261442432","url":null,"abstract":"<p><p>BackgroundResearch indicates a significant overlap between transgender and gender-diverse (TGD) and autistic identities. This intersectional population has higher risks of mental health challenges and worse mental health outcomes than individuals with just one of the two identities. Limited research focuses on adults at this intersection and their care access needs. To better characterize this population in the Canadian context, this study examines the population referred to Canada's largest publicly funded adult gender-related care clinic and compares demographic and diagnostic characteristics between those with and without a pre-existing autism diagnosis.MethodsThe data come from the medical records of 1,843 adults referred to the Gender Identity Clinic (GIC) at the Centre for Addiction and Mental Health in Toronto, Canada, between January 2020 and March 2025. The prevalence of autism diagnosis prior to entering the clinic was calculated. Average age, sex-assigned-at-birth composition, prevalence of gender dysphoria diagnoses and of additional mental health and neurodevelopmental diagnoses were compared between autistic and non-autistic groups. Changes across time in the number of autistic individuals referred to the GIC were analyzed.ResultsApproximately 6.3% of adults referred to GIC had a diagnosis of autism. The autistic and non-autistic groups had no difference in average age. The groups had no differences in sex-assigned-at-birth distribution. Autistic adults had greater rates of gender dysphoria. Autistic adults had higher rates of each category of mental health and neurodevelopmental diagnoses examined.ConclusionsThis study is a first step in developing a holistic understanding of the experiences of autistic TGD adults seeking clinical gender-related care in the Canadian context, providing a starting point to addressing needs and barriers to care for this population, as well as insight into the substantial mental health challenges experienced by this population.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261442432"},"PeriodicalIF":3.8,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functionality in Clinically Recovered Subjects with Obsessive-Compulsive Disorder: A Case-Control Study: Capacité fonctionnelle des sujets atteints d'un trouble obsessionnel-compulsif qui obtiennent un rétablissement clinique - Étude cas-témoins.","authors":"T S Jaisoorya, Paulomi M Sudhir, Thennarassu Kandavel, Y C Janardhan Reddy","doi":"10.1177/07067437261442377","DOIUrl":"10.1177/07067437261442377","url":null,"abstract":"<p><p>ObjectiveA proportion of patients suffering from obsessive-compulsive disorder (OCD) achieves clinical recovery. However, research is sparse on the functional recovery of clinically recovered subjects with OCD. This study examines functionality in clinically recovered OCD subjects compared to healthy controls (HCs).MethodPatients who had clinically recovered from OCD (<i>n</i> = 102) were compared to HCs (<i>n</i> = 52) with respect to global functioning, well-being, disability, and quality of life (QOL) using the Global Assessment of Functioning (GAF) Scale, the WHO-5 Well-Being Scale, the WHO-Disability Assessment Schedule, and the WHO-Quality of Life-Brief Version respectively. They also underwent a comprehensive neuropsychological assessment.ResultsClinically recovered OCD patients had lower global functioning, higher disability scores, impaired environment QOL, and poorer neuropsychological performance in the domains of working memory and response inhibition compared to HCs. In the Spearman's correlation analysis, better global functioning in clinically recovered OCD patients correlated with a longer period of clinical recovery, receiving pharmacological augmentation, not receiving cognitive behavioural therapy, lower disability scores, a higher well-being score, and a higher total QOL score. Neuropsychological correlates of better functioning included faster processing speed and greater accuracy in working memory tasks. In a stepwise quantile (median) regression analysis, improved functioning was associated with an older age of onset, longer duration of remission, faster processing speed, better working memory, lower total disability scores, and higher total QOL scores.ConclusionsClinically recovered OCD patients have a lower functionality. Functional recovery may be defined as clinical recovery and a GAF score of >70 (no more than slight impairment in functioning and minimal symptoms, if any). It is important to identify those who have not achieved functional recovery and offer interventions, including cognitive remediation to improve functional outcomes.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261442377"},"PeriodicalIF":3.8,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13099742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}