Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie最新文献

{"title":"Corrigendum to \"Dynamic Postural Control in Remitted Bipolar I Disorder: A Computerized Dynamic Posturography Study: Contrôle postural dynamique chez les personnes atteintes d'un trouble bipolaire de type I en rémission : Étude de posturographie dynamique informatisée\".","authors":"","doi":"10.1177/07067437261446372","DOIUrl":"10.1177/07067437261446372","url":null,"abstract":"","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"886-887"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Postural Control in Remitted Bipolar I Disorder: A Computerized Dynamic Posturography Study: Contrôle postural dynamique chez les personnes atteintes d'un trouble bipolaire de type I en rémission : Étude de posturographie dynamique informatisée.","authors":"Rahina Abubacker, Pradeep Yuvaraj, Aravind Kumar Rajasekaran, Aravinda Hanumanthapura Ramalingaiah, Binukumar Bhaskarpillai, Michael Berk, Lakshmi N Yatham, Muralidharan Kesavan","doi":"10.1177/07067437261426621","DOIUrl":"10.1177/07067437261426621","url":null,"abstract":"<p><p>BackgroundEmerging evidence suggests overlap in brain areas implicated in the pathophysiology of bipolar I disorder (BD-I) and vestibular activity in the brainstem, potentially underlying the postural instability observed in BD-I. Computerized Dynamic Posturography (CDP), a validated tool that quantifies the functional contributions of somatosensory, visual, and vestibular inputs, as well as the central mechanisms responsible for integrating these inputs, was employed to examine the sensory processing and postural control in BD-I.Aims and ObjectivesTo investigate the integrity of dynamic postural control and the contributions of somatosensory, visual, and vestibular sensory systems to postural stability in individuals with BD-I in remissionMethodThirty participants aged 18-50 years with BD-I in remission (ICD-11; female = 12), not on known vestibular suppressants, and 30 matched controls (female = 13) underwent CDP, which included the Sensory Organization Test (SOT), adaptation test, Motor Control Test (MCT), fall risk test, and Optokinetic test (OKN). The differences between the groups were assessed using an independent samples <i>t</i>-test.ResultsBD-I participants showed significantly poorer scores on SOT, fall risk test, and OKN test (all <i>p</i> < 0.005). We did not find significant differences in the adaptation test and MCT.Discussion and ConclusionsBD-I subjects exhibited greater postural alterations compared to healthy controls, indicating impaired sensory integration, especially when visual input was altered. Fall risk and OKN tests suggest central deficits in processing vestibular and proprioceptive input. These findings support postural control assessment as a potential biomarker for BD-I, though medication effects remain an important consideration.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"871-881"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12956612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147345624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on ADHD genetics: A practitioner's perspective: Mise à jour sur la génétique du TDAH : le point de vue d'un praticien.","authors":"Russell Schachar, Jennifer Crosbie, Paul D Arnold, Christie L Burton","doi":"10.1177/07067437261457230","DOIUrl":"10.1177/07067437261457230","url":null,"abstract":"<p><p>BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition characterized by early-onset inattention, hyperactivity, and impulsiveness. Affecting 5% to 10% of youth and persisting into adulthood in ∼6%, ADHD is frequently discussed in genetic terms by patients and their families, making it essential for clinicians to understand current genetic evidence.ObjectiveTo summarize contemporary genetic findings relevant to ADHD across the lifespan and provide practical guidance for clinicians on assessment, treatment, and psychoeducation.Scope and methodsThis focused narrative review integrates evidence from family and twin studies, genome-wide association studies (GWAS), copy number variants (CNVs), polygenic risk scores (PRS), and Mendelian randomization (MR), as well as pharmacogenetics and studies of gene-environment interplay.FindingsADHD is highly heritable (∼70%), comparable to other major neuropsychiatric conditions. GWAS reveals that thousands of common variants collectively contribute to risk (i.e., polygenic), though each has a small effect. Rare CNVs are more frequent in ADHD than controls and overlap with CNVs in autism. Genetic findings implicate neurodevelopmental pathways expressed in early brain and frontal cortical circuits. ADHD genetic risk correlates with cognitive traits, risk-taking behaviours, and multiple psychiatric and physical health outcomes. Gene-environment correlations and interactions influence risk and course. Pharmacogenetic evidence supports <i>CYP2D6</i> genotyping for atomoxetine dosing; routine genetic testing for stimulant selection is not justified.Clinical implicationsThere are no diagnostic genetic tests for ADHD. Assessment should prioritize functional impairment, developmental and family history, and comorbidity. Psychoeducation should emphasize modifiable risks and the interplay of genes and the environment. While genetic insights may eventually refine diagnosis and personalized care, current best practice relies on comprehensive clinical evaluation and multimodal management.ConclusionGenetic research confirms ADHD's neurodevelopmental basis, continuity across the lifespan, and overlap with other neurodevelopmental conditions of childhood. Clinicians can use these insights for counselling and risk monitoring while avoiding over-reliance on genetic testing outside targeted pharmacogenetic use.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"830-839"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13272195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Homelessness and Mental Healthcare Utilization Among People With Addictions and Mental Health Problems: A Population-Based Study From Alberta Canada.","authors":"Rebecca Barry, Geoffrey Messier, Anees Bahji, Mohammad Ziaul Islam Chowdhury, Gina Dimitropoulos, Sumantra Monty Ghosh, Julia Kirkham, Scott B Patten, Katherine Rittenbach, Faezehsadat Shahidi, David Tano, Valerie H Taylor, Dallas P Seitz","doi":"10.1177/07067437261462692","DOIUrl":"10.1177/07067437261462692","url":null,"abstract":"<p><p>ObjectiveAddiction and mental health (AMH) disorders present significant psychosocial challenges among affected individuals. Previous research indicates a higher prevalence of AMH conditions among people experiencing homelessness (PEH). This study aims to determine the risk of mortality, suicide attempts, emergency department (ED) visits and hospitalizations among PEH with AMH conditions compared to individuals with AMH conditions who had not experienced homelessness in Alberta.MethodsThis retrospective cohort study used linked administrative data from Alberta Health Services from April 1, 2013 to March 31, 2023. We included adults residing in Alberta and diagnosed with any AMH condition within 5 years before the index date of April 1, 2018. Homelessness in the year prior to the index date was identified using relevant codes in records representing hospitalizations and ED visits. We used Cox Proportional Hazards models to evaluate the risk of ED visits, hospitalizations, suicide attempts, and all-cause mortality for up to 5 years, adjusted for age and sex. We also conducted matched propensity score analyses.ResultsAmong the 622,614 individuals with AMH conditions, 3,390 (0.54%) had an indicator of homelessness. In age and sex-adjusted analyses, PEH were at greater risk for ED visits for both AMH (HR = 8·75, 95% CI [8.37-9.16]) and non-AMH (HR = 2.56, HR = 2.47-2.63) reasons, and at greater risk of hospitalizations for AMH (HR = 8.34, 95% CI [7.73-9.00]) and non-AMH (HR = 6.03, 95% CI [5.73-6.35]) reasons. PEH were at greater risk of suicide attempts (HR = 9.18, 95% CI [8.43-10.01]) and all-cause mortality (HR = 8.15, 95% CI [7.56-8.79]). Findings were attenuated but still significant in the propensity-matched analyses.ConclusionsPEH are at much greater risk of ED visits, hospitalizations, suicide attempts and all-cause mortality. Given this population's high risk of adverse outcomes, PEH will likely need more intensive mental and physical healthcare, coordinated with housing and social support services. Further research is needed on the implementation of interventions tailored to the needs of PEH.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"850-858"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Intersection of Autism and Gender Diversity in the Canadian Clinical Context: Characterizing a Sample of Adults Referred to Canada's Largest Publicly Funded Adult Gender-Care Service: Intersection de l'autisme et de la diversité des identités de genre dans le contexte clinique canadien : Caractérisation d'un échantillon d'adultes orientés vers le plus grand service de soins en matière d'identité de genre destinés aux adultes financé par le secteur public au Canada.","authors":"Molly Isabel Pascoe, Jacqueline Vincent, Meng-Chuan Lai, Pushpal Desarkar, Nina Vitopoulos, Yona Lunsky, Kinnon Ross MacKinnon, June Sing Hong Lam","doi":"10.1177/07067437261442432","DOIUrl":"10.1177/07067437261442432","url":null,"abstract":"<p><p>BackgroundResearch indicates a significant overlap between transgender and gender-diverse (TGD) and autistic identities. This intersectional population has higher risks of mental health challenges and worse mental health outcomes than individuals with just one of the two identities. Limited research focuses on adults at this intersection and their care access needs. To better characterize this population in the Canadian context, this study examines the population referred to Canada's largest publicly funded adult gender-related care clinic and compares demographic and diagnostic characteristics between those with and without a pre-existing autism diagnosis.MethodsThe data come from the medical records of 1,843 adults referred to the Gender Identity Clinic (GIC) at the Centre for Addiction and Mental Health in Toronto, Canada, between January 2020 and March 2025. The prevalence of autism diagnosis prior to entering the clinic was calculated. Average age, sex-assigned-at-birth composition, prevalence of gender dysphoria diagnoses and of additional mental health and neurodevelopmental diagnoses were compared between autistic and non-autistic groups. Changes across time in the number of autistic individuals referred to the GIC were analyzed.ResultsApproximately 6.3% of adults referred to GIC had a diagnosis of autism. The autistic and non-autistic groups had no difference in average age. The groups had no differences in sex-assigned-at-birth distribution. Autistic adults had greater rates of gender dysphoria. Autistic adults had higher rates of each category of mental health and neurodevelopmental diagnoses examined.ConclusionsThis study is a first step in developing a holistic understanding of the experiences of autistic TGD adults seeking clinical gender-related care in the Canadian context, providing a starting point to addressing needs and barriers to care for this population, as well as insight into the substantial mental health challenges experienced by this population.Plain Language Summary TitleCharacterizing the population of autistic adults visiting a large gender-care service in Canada.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"840-849"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Correlates of Post-Traumatic Stress Disorder Symptoms During the COVID-19 Pandemic in Canada: A Systematic Review and Meta-analysis: Prévalence et corrélats des symptômes du trouble de stress post-traumatique pendant la pandémie de COVID-19 au Canada : Revue systématique et méta-analyse.","authors":"Jude Mary Cénat, Wina Paul Darius, Seyed Mohammad Mahdi Moshirian Farahi, Taddele Cherinet Kibret, Eden Samson, Runzhi Chen, Seung Won Kuk, Khanyisa Ogbuaku Jnr, Evelyn Steacy, Patrick R Labelle, Sheri Madigan, Rose Darly Dalexis","doi":"10.1177/07067437251408179","DOIUrl":"10.1177/07067437251408179","url":null,"abstract":"<p><p>BackgroundInfectious disease outbreaks have been associated with significant psychological distress and trauma. In Canada, the COVID-19 pandemic's social disruptions have heightened mental health risks. While global studies report elevated posttraumatic stress disorder (PTSD) symptoms, Canadian findings remain limited and inconsistent. This meta-analysis estimated pooled prevalence of PTSD symptoms in Canada during the COVID-19 pandemic and examined potential moderators.MethodsA comprehensive search strategy was executed by research librarians across five databases (APA PsycInfo, CINAHL, Embase, MEDLINE and Web of Science) and on LitCovid. The PRISMA guidelines were used for data extraction and reporting. Random-effects meta-analyses were conducted to estimate pooled PTSD symptoms prevalence and explore potential moderators using the metaprop command in STATA/SE 19.5.ResultsThirty studies conducted between 2020 and 2022, with 52,565 participants aged 18 and older were included (65% weighted women). The pooled prevalence of PTSD symptoms was 22.2% (95% CI, 15.7% to 29.4%; I²=99.69). Prevalence was 32.1% in women, 26.1% in men (<i>p</i> = 0.399) and ranged from 16.1% in Quebec to 29.7% in Ontario (<i>p</i> = 0.091). Meta-regressions showed lower PTSD symptoms prevalence in Quebec (B=-0.16, <i>p</i> = 0.029). No significant differences in PTSD symptoms were found according to sex, healthcare worker status, assessment tool used, or data collection year.ConclusionsThis meta-analysis reveals a concerning prevalence of PTSD symptoms in the Canadian population during the COVID-19 pandemic. Contrary to expectations, no significant differences were found by sex or healthcare worker status, suggesting widespread psychological distress across the population. However, the substantial heterogeneity across studies limits the interpretation of these findings in the context of the COVID-19 pandemic. The results emphasize the need for inclusive and accessible mental health responses and further research on post-pandemic Canadians' mental health. Future studies should better disaggregate data by sex, age and race to address disparities and inform targeted public health policies and interventions.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"815-829"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12851921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological Cautions in Interpreting Autism and Gender Dysphoria in a Referred Clinical Sample.","authors":"Irina Dinu, Chan Kulatunga-Moruzi, Ari R Joffe","doi":"10.1177/07067437261471757","DOIUrl":"10.1177/07067437261471757","url":null,"abstract":"<p><p></p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"882-883"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13486382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Trends and Patterns of ADHD Medication Use Among Children, Adolescents and Young Adults in Quebec, Canada: A Repeated Cross-Sectional Population-Based Study From 2000 to 2022: Prévalence, tendances et profils d'utilisation des médicaments pour le TDAH chez les enfants, les adolescents et les jeunes adultes au Québec (Canada) : étude populationnelle transversale répétée, 2000-2022.","authors":"Martin Gignac, Alvine A K Fansi, Carlotta Lunghi, Fatoumata Binta Diallo, Louis Rochette, Victoria Massamba, Helen-Maria Vasiliadis, Elham Rahme, Samuele Cortese, Alain Lesage","doi":"10.1177/07067437261471748","DOIUrl":"10.1177/07067437261471748","url":null,"abstract":"<p><p>ObjectiveThe prevalence of attention-deficit/hyperactivity disorder (ADHD) has risen in recent decades. The objective of this study was to identify trends in prevalence rates of ADHD medication use as well as any patterns of ADHD medication use among individuals aged up to 24 years in Quebec, Canada.MethodWe conducted a repeated cross-sectional study using medico-administrative data between the fiscal years 2000 to 2001 and 2022 to 2023. We estimated crude and age-adjusted prevalence rates along with their 99% confidence intervals according to sex, age (only for crude estimates), material and social deprivation, and ADHD medication type, namely stimulants (amphetamine-based and methylphenidate-based medications) and non stimulants (atomoxetine and guanfacine). We also analyzed prescribing by prescriber type.ResultsAmong the 4,771,183 individuals aged ≤24 years, 7.7% claimed ADHD medications. Age-adjusted prevalence of ADHD medication use increased from 2000 to 2001 (1.9%) until 2017 to 2018 (7.9%) and plateaued afterwards. The analysis highlighted not only variations in medication use over time but also by sex, with males more likely to be prescribed these medications than females. Family physicians have become the primary prescribers, overtaking pediatricians in recent years. Stimulant medications were the most common treatment throughout the study period, though we observed diversification in prescribed ADHD medication types across age groups.ConclusionsThis study emphasizes a significant increase in ADHD medication use from 2000 to 2018 and a stabilization in use afterwards. The expansion of diagnostic criteria in 2013 and heightened awareness may have narrowed the disparity between the condition's prevalence and its management and may explain the increase in use observed in earlier years and the stabilization observed over the more recent years. The disparities between males and females, as well as between age groups, highlight the need for continuous monitoring of prescribing trends and support targeted equity evaluations to inform service planning and improve access where needed.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"859-870"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148834991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and Workload Measurement in Defining Child-Focused Psychiatrists in Ontario.","authors":"Noor Un Nisa, Syeda Ukasha Mati","doi":"10.1177/07067437261467111","DOIUrl":"10.1177/07067437261467111","url":null,"abstract":"","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"884-885"},"PeriodicalIF":4.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13354592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Irritability in Adult Depression and Anxiety: A Clinically Useful Signal Amid an Imprecise Construct.","authors":"Michael Uebel","doi":"10.1177/07067437261490170","DOIUrl":"10.1177/07067437261490170","url":null,"abstract":"<p><p>A brief consideration of the conceptual and diagnostic tidiness of irritability associated with depression and anxiety in adults. Despite evidence for its conceptual untidiness, there are practical issues that the clinician may consider when diagnosing and treating depression or anxiety.</p>","PeriodicalId":55283,"journal":{"name":"Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie","volume":" ","pages":"7067437261490170"},"PeriodicalIF":4.4,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}