Cell Communication and Adhesion最新文献_第7页

The connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane. connexin43相互作用蛋白CIP85介导connexin43从质膜内化。

Cell Communication and Adhesion Pub Date : 2013-08-01 Epub Date: 2013-04-16 DOI: 10.3109/15419061.2013.784745

Kimberly Cochrane, Vivian Su, Alan F Lau

引用次数: 15

A nanofibrous PHBV tube with Schwann cell as artificial nerve graft contributing to rat sciatic nerve regeneration across a 30-mm defect bridge. 纳米纤维PHBV管与雪旺细胞作为人工神经移植物在大鼠坐骨神经缺损桥上的修复作用。

Cell Communication and Adhesion Pub Date : 2013-02-01 Epub Date: 2013-03-05 DOI: 10.3109/15419061.2013.774378

Esmaeil Biazar, Saeed Heidari Keshel

引用次数: 58

Desmosomal adhesion and pemphigus vulgaris: the first half of the story. 桥粒粘连和寻常型天疱疮:故事的前半部分。

Cell Communication and Adhesion Pub Date : 2013-02-01 DOI: 10.3109/15419061.2013.763799

Nicola Cirillo, Badr A Al-Jandan

{"title":"Desmosomal adhesion and pemphigus vulgaris: the first half of the story.","authors":"Nicola Cirillo, Badr A Al-Jandan","doi":"10.3109/15419061.2013.763799","DOIUrl":"https://doi.org/10.3109/15419061.2013.763799","url":null,"abstract":"Pemphigus vulgaris (PV) is a paradigm of autoimmune disease affecting intercellular adhesion. The mechanisms that lead to cell-cell detachment (acantholysis) have crucial therapeutic implications and are currently undergoing major scrutiny. The first part of this review focuses on the classical view of the pathogenesis of PV, which is dominated by the cell adhesion molecules of the desmosome, namely desmogleins (Dsgs). Cloning of the DSG3 gene, generation DSG3 knock-out mice and isolation of monoclonal anti-Dsg3 IgG have aided to clarify the pathogenic mechanisms of PV, which are in part dependent on the fate of desmosomal molecules. These include perturbation of the desmosomal network at the transcriptional, translational, and interaction level, kinase activation, proteinase-mediated degradation, and hyper-adhesion. By the use of PV models, translational research has in turn helped shed light into the basic structure, function, and dynamics of assembly of desmosomal cadherins. The combined efforts of basic and applied research has resulted in tremendous advance into the understanding of epidermal adhesion and helped debunk old myths on the supposedly unique role of desmogleins in the mechanisms of cell-cell detachment in PV.","PeriodicalId":55269,"journal":{"name":"Cell Communication and Adhesion","volume":"20 1-2","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2013-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/15419061.2013.763799","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31204388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

A history of gap junction structure: hexagonal arrays to atomic resolution. 间隙结结构的历史:六角形阵列到原子分辨率。

Cell Communication and Adhesion Pub Date : 2013-02-01 Epub Date: 2013-03-08 DOI: 10.3109/15419061.2013.775256

Rosslyn Grosely, Paul L Sorgen

引用次数: 12

Role of transcription factors in the pathogenesis of asthma and COPD. 转录因子在哮喘和COPD发病机制中的作用。

Cell Communication and Adhesion Pub Date : 2013-02-01 Epub Date: 2013-03-11 DOI: 10.3109/15419061.2013.775257

Gaetano Caramori, Paolo Casolari, Ian Adcock

引用次数: 45

Isolation and biological characteristics of beijing Fatty chicken skeletal muscle satellite cells. 北京肥鸡骨骼肌卫星细胞的分离及生物学特性研究。

Cell Communication and Adhesion Pub Date : 2012-10-01 Epub Date: 2012-11-23 DOI: 10.3109/15419061.2012.743998

Chunyu Bai, Lingling Hou, Fanghua Li, Xiaohong He, Minghai Zhang, Weijun Guan

引用次数: 12

Effects of exogenous ganglioside GM1 on different stages of cell spreading studied by directly quantifying spreading rate. 通过直接定量研究外源神经节苷脂GM1对细胞扩散不同阶段的影响。

Cell Communication and Adhesion Pub Date : 2012-10-01 Epub Date: 2012-11-26 DOI: 10.3109/15419061.2012.749245

Jie Huang, Wenxiang Shao, Li Wu, Wen Yang, Yong Chen

{"title":"Effects of exogenous ganglioside GM1 on different stages of cell spreading studied by directly quantifying spreading rate.","authors":"Jie Huang, Wenxiang Shao, Li Wu, Wen Yang, Yong Chen","doi":"10.3109/15419061.2012.749245","DOIUrl":"https://doi.org/10.3109/15419061.2012.749245","url":null,"abstract":"We developed novel methods to directly quantify cell spreading rate. By comparing our methods with traditional methods, we found that the enhancement effects of fetal calf serum (FCS) or the inhibitory effects of exogenous ganglioside GM1 occurred at different stages of cell spreading. GM1 mainly influenced the early and late stages of cell spreading of HUVECs. In the presence of 0.5% FCS, GM1 significantly impaired the area-based spreading rates (127.4 ± 35.7 μm(2)/h and 22.2 ± 3.8 μm(2)/h, respectively) on the early (0-0.5 h) and late (12-24 h) stages of cell spreading compared with the controls (238.1 ± 11.7 μm(2)/h and 35.4 ± 19.5 μm(2)/h, respectively), which was confirmed by the data on the GM1-induced changes in average length of actin filaments during cell spreading. The real-time observation and quantification of cold-induced de-spreading of GM1-free or GM1-treated HUVECs further confirmed that GM1 can influence cell de-spreading process having inhibitory (0-10 min) or enhancement (10-20 min or 40-50 min) effects on different stages. The methods can be recruited for investigating effects of other reagents on different stages of cell spreading.","PeriodicalId":55269,"journal":{"name":"Cell Communication and Adhesion","volume":"19 5-6","pages":"85-95"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/15419061.2012.749245","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31075222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The cytological observation of immune adherence of porcine erythrocyte. 猪红细胞免疫粘附的细胞学观察。

Cell Communication and Adhesion Pub Date : 2012-10-01 Epub Date: 2012-11-14 DOI: 10.3109/15419061.2012.743999

Yao-Gui Sun, Wei Yin, Xin-Feng Fan, Kuo-Hai Fan, Jun-Bing Jiang, Hong-Quan Li

{"title":"The cytological observation of immune adherence of porcine erythrocyte.","authors":"Yao-Gui Sun, Wei Yin, Xin-Feng Fan, Kuo-Hai Fan, Jun-Bing Jiang, Hong-Quan Li","doi":"10.3109/15419061.2012.743999","DOIUrl":"https://doi.org/10.3109/15419061.2012.743999","url":null,"abstract":"The immune adherence (IA) between the porcine erythrocytes and the opsonized Escherichia coli carried green fluorescent protein gene (GFP-E.coli) were detected by the fluorescence microscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) with an attempt to verify the existence of IA between the porcine erythrocytes and complemented-opsonized microbes. Under fluorescence microscopy, GFP-E.coli opsonized by fresh rabbit serum complement adhered to the erythrocytes and could not be detached by PBS washing, and no IA was observed between the erythrocytes and nonopsonized GFP-E.coli after co-incubation. SEM and TEM also revealed the existence of IA between the serum complement-opsonized GFP-E.coli membrane and the erythrocyte membrane. The partial complement receptor type 1 (CR1)-like gene from porcine was generated by RT-PCR and rapid amplification of cDNA 3' end (3' RACE) (157bp and 578bp), both of which have high similarity with published mammal's CR1 gene. The sequences were spliced based on homology comparison and submitted to GenBank (GenBank Accession No. JX033989). These results indicated that the porcine erythrocytes were able to bind to the opsonized microorganisms. Furthermore, the sequencing results confirmed that the CR1-like gene exists in porcine.","PeriodicalId":55269,"journal":{"name":"Cell Communication and Adhesion","volume":"19 5-6","pages":"79-84"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/15419061.2012.743999","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31049102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Regulatory function of trefoil peptides (TFF) on intestinal cell junctional complexes. 三叶肽(TFF)对肠细胞连接复合物的调控作用。

Cell Communication and Adhesion Pub Date : 2012-10-01 Epub Date: 2012-11-26 DOI: 10.3109/15419061.2012.748326

Andrea Buda, Mark A Jepson, Massimo Pignatelli

{"title":"Regulatory function of trefoil peptides (TFF) on intestinal cell junctional complexes.","authors":"Andrea Buda, Mark A Jepson, Massimo Pignatelli","doi":"10.3109/15419061.2012.748326","DOIUrl":"https://doi.org/10.3109/15419061.2012.748326","url":null,"abstract":"Abstract Trefoil peptides (TFF) are constitutively expressed in the gastrointestinal tract and are involved in gastrointestinal defence and repair by promoting epithelial restitution. Although there is a general consensus regarding the pro-motogenic activity of trefoil peptides, the cellular mechanisms through which they mediate these processes are not completely understood. Pertubation of the E-cadherin/catenin complex at intercellular junctions appears to be a functional pathway through which TFF2 and TFF3 promote cell migration. Tight junction complexes seal the paracellular spaces between cells and contribute to epithelial barrier function. TFF3 peptide stimulation stabilises these junctions through upregulation of the tightening protein claudin-1 and redistribution of ZO-1 from the cytoplasm to the intercellular membrane with an increase in binding to occludin. Modulation of the functional activity and subcellular localisation of epithelial junctional adhesion molecules represent important mechanisms by which trefoil peptides may promote migration of intestinal epithelial cells in vitro and healing of mucosal damage in vivo.","PeriodicalId":55269,"journal":{"name":"Cell Communication and Adhesion","volume":"19 5-6","pages":"63-8"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/15419061.2012.748326","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31074780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 38

Modifications in connexin expression in liver development and cancer. 连接蛋白在肝脏发育和癌症中的表达改变。

Cell Communication and Adhesion Pub Date : 2012-08-01 Epub Date: 2012-09-05 DOI: 10.3109/15419061.2012.712576

Mathieu Vinken, Joery De Kock, André G Oliveira, Gustavo B Menezes, Bruno Cogliati, Maria Lúcia Zaidan Dagli, Tamara Vanhaecke, Vera Rogiers

引用次数: 23