Concepts in Magnetic Resonance Part A最新文献

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Diffusion measurements using the second echo 利用二次回波进行扩散测量
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-04-26 DOI: 10.1002/cmr.a.21462
Hilary T. Fabich, Partha Nandi, Hans Thomann, Mark S. Conradi
{"title":"Diffusion measurements using the second echo","authors":"Hilary T. Fabich,&nbsp;Partha Nandi,&nbsp;Hans Thomann,&nbsp;Mark S. Conradi","doi":"10.1002/cmr.a.21462","DOIUrl":"10.1002/cmr.a.21462","url":null,"abstract":"<p>We present a tutorial discussion of diffusion measurements by NMR, aimed around a specific problem. To measure diffusion in the presence of convective flow, one may use the second echo using the well-known cancellation of phase effects from flow for the second echo. In testing this with a simple organic liquid and a static (dc) gradient at room temperature, where no convection can occur, we noticed the data from the second echo implied a substantially <i>larger</i> rate of diffusion than for the first echo. The error is due to the second echo being a superposition of a spin (Hahn) echo (an echo of the first echo) and a stimulated echo. We show that the stimulated echo is more attenuated by diffusion (it has a larger <i>b</i> value), explaining our result. A simple phase cycle is presented that suppresses the stimulated echo and leads to the correct diffusion value from the second echo. That is, the diffusion values taken from the first and second echoes are now identical.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21462","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83652726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Sensitivity estimation in circular and square loops 圆形和方形回路的灵敏度估计
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-04-26 DOI: 10.1002/cmr.a.21461
Giulio Giovannetti
{"title":"Sensitivity estimation in circular and square loops","authors":"Giulio Giovannetti","doi":"10.1002/cmr.a.21461","DOIUrl":"10.1002/cmr.a.21461","url":null,"abstract":"<p>Circular and square loops are the simplest design employed as radiofrequency coils for magnetic resonance applications. Being usually much smaller than the volume coils, these loop coils have higher signal-to-noise ratio (SNR) because they receive noises only from nearby regions. However, they have a relatively poor field homogeneity and, thus, are mainly used as receive coils. In this work, author describes a coil sensitivity estimation method based on a simulator which permits the characterization of loop coils performance, in terms of magnetic field patterns and coil losses, where this last term including conductor, sample, capacitor, radiative and soldering losses. The evaluation of coil sensitivity for circular and square loops was performed at different tuning frequencies usually used in clinical scanner (21, 64, and 128 MHz) and at different distances respect to the coil plane. Simulation data were acquired for circular loop radius between 0.5 and 4 cm and for square loop side sizes between 1 and 8 cm, with the scope of evaluating the loop sizes which maximize the sensitivity in dependence of the penetration depth in the sample region and therefore to design optimized coils for maximizing SNR in MR applications.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21461","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79573666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Aspects of NMR reciprocity and applications in highly conductive media 核磁共振互易性及其在高导电介质中的应用
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-04-26 DOI: 10.1002/cmr.a.21466
Andrew J. Ilott, Alexej Jerschow
{"title":"Aspects of NMR reciprocity and applications in highly conductive media","authors":"Andrew J. Ilott,&nbsp;Alexej Jerschow","doi":"10.1002/cmr.a.21466","DOIUrl":"10.1002/cmr.a.21466","url":null,"abstract":"<p>In the context of NMR spectroscopy and MRI, the principle of reciprocity provides a convenient method for determining the reception sensitivity from the transmitted rf field pattern. The reciprocity principle for NMR was originally described by Hoult et al (<i>J Magn Reson</i>. 1976;<b>24</b>:71) and is related to the broader Lorentz reciprocity principle and similar theorems from antenna theory. One frequent application of the reciprocity principle is that for a single coil used for both transmission and detection, the transmit and receive fields can be assumed to be equal. This aspect is also where some of the conceptual difficulty of applying the theorem may be encountered. For example, the questions of whether one should use the complex conjugate field for detection or whether one should apply the theorem in the rotating frame or in the laboratory frame may give rise to considerable confusion. We attempt here to provide a helpful discussion of the application of the reciprocity principle in such a way as to clarify some of the confounding questions. In particular, we avoid the use of the “negatively rotating frame,” which is frequently mentioned in this context, since we consider it to unnecessarily complicate the matter. In addition, we also discuss the implications of the theorem for magnetic resonance experiments on conducting samples, and metals, in particular.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73503767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Magnetic resonance data modeling: The Bayesian analysis toolbox 磁共振数据建模:贝叶斯分析工具箱
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-04-26 DOI: 10.1002/cmr.a.21467
James D. Quirk, G. Larry Bretthorst, Joel R. Garbow, Joseph J. H. Ackerman
{"title":"Magnetic resonance data modeling: The Bayesian analysis toolbox","authors":"James D. Quirk,&nbsp;G. Larry Bretthorst,&nbsp;Joel R. Garbow,&nbsp;Joseph J. H. Ackerman","doi":"10.1002/cmr.a.21467","DOIUrl":"10.1002/cmr.a.21467","url":null,"abstract":"<p>Bayesian probability theory provides optimal parameter estimates and robust model selection from a family of competing data models. However, widespread adoption of the Bayesian approach to the analysis of magnetic resonance and other data types has been hindered by its perceived complexity and heavy computational burden. This manuscript describes the Bayesian Analysis Toolbox, a computationally efficient, robust, and highly optimized suite of data modeling software packages based upon the precepts of Bayesian probability theory. The Toolbox is downloadable at no cost for noncommercial applications from http://bayesiananalysis.wustl.edu. The Toolbox extends Bayesian-based data analysis to a variety of real-world data analysis problems commonly encountered in spectroscopy and imaging, with a focus on magnetic resonance-derived data, making the power of this approach available to the non-expert user.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21467","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74276379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
The past, present, and future of 1.26T2 1.26T2的过去、现在和未来
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-04-26 DOI: 10.1002/cmr.a.21473
David Rovnyak
{"title":"The past, present, and future of 1.26T2","authors":"David Rovnyak","doi":"10.1002/cmr.a.21473","DOIUrl":"10.1002/cmr.a.21473","url":null,"abstract":"<p>This mini-review considers the scientific and historical development of the constant 1.26<i>T</i><sub>2</sub>, which represents the acquisition time for which the signal-to-noise ratio of a decaying exponential (with time constant <i>T</i><sub>2</sub>) is a maximum in the presence of thermal noise. While first reported in 1977, interest in this result greatly increased after about the year 2000, when it began to influence thinking in nonuniform sampling, sensitivity, and pulse sequence design. Overall, 1.26<i>T</i><sub>2</sub> has become a lens through which to view the evolution of NMR data acquisition and processing. An enduring lesson of the 1.26<i>T</i><sub>2</sub> story is the value of describing and analyzing the properties of magnetic resonance signals in the time domain prior to any further spectral analysis and processing, a concept which is at the core of many modern analytic techniques.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21473","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77947622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Foodomics and storage monitoring of three meat cuts by 1H NMR 三种肉块的食物组学及1H NMR储存监测
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-04-26 DOI: 10.1002/cmr.a.21474
José Eraldo do Nascimento Fontes, Magdevis Yanet Rodriguez-Caturla, Anderson S. Sant'Ana, Thiago Inácio Barros Lopes, Anita Jocelyne Marsaioli
{"title":"Foodomics and storage monitoring of three meat cuts by 1H NMR","authors":"José Eraldo do Nascimento Fontes,&nbsp;Magdevis Yanet Rodriguez-Caturla,&nbsp;Anderson S. Sant'Ana,&nbsp;Thiago Inácio Barros Lopes,&nbsp;Anita Jocelyne Marsaioli","doi":"10.1002/cmr.a.21474","DOIUrl":"10.1002/cmr.a.21474","url":null,"abstract":"<p>The growth of NMR foodomics is described in the context of a study of beef storage. Thirty samples of three meat cuts (chuck, sirloin, and tenderloin) were analyzed using <sup>1</sup>H NMR spectroscopy to determine the influence of storage period and temperature. <sup>1</sup>H showed signals belonging to metabolites namely: acetate, adenosine, adenine, ADP, alanine, betaine, creatine, creatinine, carnosine, fumarate, glycerol, glycine, glutamine, isoleucine, lactate, leucine, methionine, and valine. The score plots (PCA) separated the samples of different storage time, reflecting possible meat degradation. Samples of no storage time (time zero) were grouped in the PC1 and PC2 negatives axis. The score plots suggest that the temperature has a huge influence on the degradation extent and possible influences the growth of the microbial populations.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21474","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73639387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Guide to simulating complex NMR probe circuits 指南模拟复杂的核磁共振探针电路
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2019-03-29 DOI: 10.1002/cmr.a.21463
Francis David Doty
{"title":"Guide to simulating complex NMR probe circuits","authors":"Francis David Doty","doi":"10.1002/cmr.a.21463","DOIUrl":"10.1002/cmr.a.21463","url":null,"abstract":"<p>S-parameter-based circuit simulators are well suited to obtaining accurate solutions of even the most complex rf probe circuits. The basic theory necessary for determining the relative <i>S/N</i> of the probe circuit, based on <i>B</i><sub>1</sub>/<i>P</i><sup>0.5</sup>, from the voltage, current, impedance, and S-parameter data that come from circuit simulators, is presented. Examples of simulator applications to circuits of increasing complexity are presented. A key requirement for effective utilization of circuit simulators in probe circuit optimizations is constructing an approximate analytical solution of the circuit, or an inverse simulation program, to accompany the direct circuit simulation, that calculates all the needed circuit component values based on minimal input data, such as <i>B</i><sub>0</sub>, desired nuclides, sample coil description, and hardware options and details such as characteristics of various leads. A method of developing the needed inverse simulation program is presented for a simplified single-coil HXY probe circuit. The inverse program is validated by the direct simulation itself. The methods are then applied to a detailed circuit that includes all significant leads, stray capacitances, couplings, and losses for a NB 28.2-T 1-mm HXYZ MAS probe. Similar HXY circuit models were validated by NMR experiments with rotor sizes from 0.75 mm to 3.2 mm at fields from 11.7 T to 21 T. Detailed HXYZ circuit model results at 11.7 T, including pulse widths, component values, voltages, and port isolations, agreed with experimental results within a few per cent. The 1200-MHz HXYZ simulation predicted a <sup>1</sup>H <i>π</i>/2 pulse of 1.3 μs at 25 W.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"47A 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21463","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37317155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
NMR Concepts 核磁共振的概念
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2018-10-07 DOI: 10.1002/cmr.a.21372
{"title":"NMR Concepts","authors":"","doi":"10.1002/cmr.a.21372","DOIUrl":"https://doi.org/10.1002/cmr.a.21372","url":null,"abstract":"","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"46A 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2018-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21372","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91812847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DVD Review DVD的评论
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2018-10-07 DOI: 10.1002/cmr.a.21374
{"title":"DVD Review","authors":"","doi":"10.1002/cmr.a.21374","DOIUrl":"https://doi.org/10.1002/cmr.a.21374","url":null,"abstract":"","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"46A 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2018-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21374","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91812846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Illustration of inversion-recovery and Carr-Purcell-Meiboom-Gill sequences by the determination of ethanol content in alcoholic beverages 倒置-恢复和Carr-Purcell-Meiboom-Gill序列测定酒精饮料中乙醇含量的说明
IF 0.6 4区 化学
Concepts in Magnetic Resonance Part A Pub Date : 2018-09-30 DOI: 10.1002/cmr.a.21460
Yves Gossuin, Quoc L. Vuong, Leonid Grunin, Laurence Van Nedervelde, Anne Pietercelie
{"title":"Illustration of inversion-recovery and Carr-Purcell-Meiboom-Gill sequences by the determination of ethanol content in alcoholic beverages","authors":"Yves Gossuin,&nbsp;Quoc L. Vuong,&nbsp;Leonid Grunin,&nbsp;Laurence Van Nedervelde,&nbsp;Anne Pietercelie","doi":"10.1002/cmr.a.21460","DOIUrl":"https://doi.org/10.1002/cmr.a.21460","url":null,"abstract":"<p>In Nuclear Magnetic Resonance (NMR) education, the introduction of the relaxation phenomenon and the relaxation times (<i>T</i><sub>1</sub> and <i>T</i><sub>2</sub>) is an important and compulsory step, as is the description of the Carr-Purcell-Meiboom-Gill (CPMG) and inversion-recovery (IR) measurement sequences. Indeed those sequences are still used nowadays for, respectively, the measurement of <i>T</i><sub>2</sub> and <i>T</i><sub>1</sub> but also in Magnetic Resonance Imaging (MRI) and NMR spectroscopy. Practical works with the students, performed for example with water, allow to illustrate this part of the teaching. In this work we propose an alternative and funny way to introduce these important topics. With a few microliters of a concentrated Gd<sup>3+</sup> solution, a few milliliters of an alcoholic beverage and a low resolution and low field NMR device, it is possible, thanks to the relaxation phenomenon and using CPMG and IR sequences, to measure the alcohol content of the beverage provided that the alcohol proton exchange with water protons is taken into account. First the method is validated with synthetic water-ethanol mixtures, then it is used to study nine different alcoholic beverages. The correlation of the ethanol volume fractions determined by NMR with the actual ethanol content of the beverages is rather good, especially for the method based on <i>T</i><sub>2</sub> relaxation, with a correlation coefficient <i>r</i><sup>2</sup> = 0.994. However, it seems that the method developed in this work always underestimates the ethanol volume fraction at high ethanol content for a reason which remains to be found.</p>","PeriodicalId":55216,"journal":{"name":"Concepts in Magnetic Resonance Part A","volume":"46A 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cmr.a.21460","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91571105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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