Current Allergy and Asthma Reports最新文献_第10页

Computer-Assisted Clinical Diagnosis and Treatment. 计算机辅助临床诊断与治疗。

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-09-01 DOI: 10.1007/s11882-023-01097-8

Nadia Hamid, Jay M Portnoy, Aarti Pandya

{"title":"Computer-Assisted Clinical Diagnosis and Treatment.","authors":"Nadia Hamid, Jay M Portnoy, Aarti Pandya","doi":"10.1007/s11882-023-01097-8","DOIUrl":"https://doi.org/10.1007/s11882-023-01097-8","url":null,"abstract":"Purpose of review: Computer-assisted diagnosis and treatment (CAD/CAT) is a rapidly growing field of medicine that uses computer technology and telehealth to aid in the diagnosis and treatment of various diseases. The purpose of this paper is to provide a review on computer-assisted diagnosis and treatment. This technology gives providers access to diagnostic tools and treatment options so that they can make more informed decisions leading to improved patient outcomes.Recent findings: CAD/CAT has expanded in allergy and immunology in the form of digital tools that enable remote patient monitoring such as digital inhalers, pulmonary function tests, and E-diaries. By incorporating this information into electronic medical records (EMRs), providers can use this information to make the best, evidence-based diagnosis and to recommend treatment that is likely to be most effective. A major benefit of CAD/CAT is that by analyzing large amounts of data, tailored recommendations can be made to improve patient outcomes and reduce the risk of adverse events. Machine learning can assist with medical data acquisition, feature extraction, interpretation, and decision support. It is important to note that this technology is not meant to replace human professionals. Instead, it is designed to assist healthcare professionals to better diagnose and treat patients.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 9","pages":"509-517"},"PeriodicalIF":5.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10393425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Air Pollution and Diet: Potential Interacting Exposures in Asthma. 空气污染和饮食:哮喘的潜在相互作用暴露。

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-09-01 DOI: 10.1007/s11882-023-01101-1

Emily Brigham, Alisa Hashimoto, Neil E Alexis

{"title":"Air Pollution and Diet: Potential Interacting Exposures in Asthma.","authors":"Emily Brigham, Alisa Hashimoto, Neil E Alexis","doi":"10.1007/s11882-023-01101-1","DOIUrl":"https://doi.org/10.1007/s11882-023-01101-1","url":null,"abstract":"Purpose of review: To provide a review of emerging literature describing the impact of diet on the respiratory response to air pollution in asthma.Recent findings: Asthma phenotyping (observable characteristics) and endotyping (mechanistic pathways) have increased the specificity of diagnostic and treatment pathways and opened the doors to the identification of subphenotypes with enhanced susceptibility to exposures and interventions. Mechanisms underlying the airway immune response to air pollution are still being defined but include oxidative stress, inflammation, and activation of adaptive and innate immune responses, with genetic susceptibility highlighted. Of these, neutrophil recruitment and activation appear prominent; however, understanding neutrophil function in response to pollutant exposures is a research gap. Diet may play a role in asthma pathogenesis and morbidity; therefore, diet modification is a potential target opportunity to protect against pollutant-induced lung injury. In particular, in vivo and in vitro data suggest the potential for diet to modify the inflammatory response in the airways, including impacts on neutrophil recruitment and function. Murine models provide compelling results in regard to the potential for dietary components (including fiber, antioxidants, and omega-3 fatty acids) to buffer against the inflammatory response to air pollution in the lung. Precision lifestyle approaches to asthma management and respiratory protection in the context of air pollution exposures may evolve to include diet, pending the results of further epidemiologic and causal investigation and with neutrophil recruitment and activation as a candidate mechanism.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 9","pages":"541-553"},"PeriodicalIF":5.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10094839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Role of Small Molecule Ligands in IgE-Mediated Allergy. 小分子配体在 IgE 媒介过敏中的作用

IF 5.4 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-09-01 Epub Date: 2023-06-23 DOI: 10.1007/s11882-023-01100-2

Kriti Khatri, Andrea O'Malley, Christina Linn, Krzysztof Kowal, Maksymilian Chruszcz

引用次数: 0

Establishing a Virtual Home Assessment Program: from Concept to Implementation as a Result of the COVID-19 Pandemic. 建立虚拟家庭评估计划:基于COVID-19大流行的从概念到实施

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-09-01 DOI: 10.1007/s11882-023-01099-6

Ryan Allenbrand, Anita DiDonna, Jenny Marshall, Kevin Kennedy

{"title":"Establishing a Virtual Home Assessment Program: from Concept to Implementation as a Result of the COVID-19 Pandemic.","authors":"Ryan Allenbrand, Anita DiDonna, Jenny Marshall, Kevin Kennedy","doi":"10.1007/s11882-023-01099-6","DOIUrl":"https://doi.org/10.1007/s11882-023-01099-6","url":null,"abstract":"Purpose of review: Environmental home assessments have traditionally been performed in-person at the homes of Children's Mercy Kansas City patients. The COVID-19 pandemic brought many challenges to the way patients interact with their healthcare providers, including home visiting programs. Reaching out to patients with high-risk asthma and immunocompromised health was still needed, despite the pandemic. This project's purpose was to develop a virtual (telemedicine) healthy home assessment protocol that would continue to meet patients' needs during the isolation resulting from the pandemic.Recent findings: This is a newly developing approach to performing home environmental assessments with limited published research. Research on the effective use of telemedicine as an alternative to in-person clinic visits has shown that for some health conditions telemedicine represents a useful technique to engage with patients and caregivers. For some conditions, like pediatric asthma, it provides a similar level of efficacy in disease management while providing a more efficient form of interaction. This article describes the development and delivery process, timelines of caregiver interaction, and guidelines for performing virtual home assessments. It summarizes the challenges and benefits of using a virtual process for delivering home assessment services for asthma and allergy patients. Overall, caregivers indicated they found the use of virtual technology had significant benefits for them including their personal comfort and the time efficiency gained by using virtual visits to interact with Healthy Homes Program staff.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 9","pages":"531-540"},"PeriodicalIF":5.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10034542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental Exposure to Foods as a Risk Factor for Food Allergy. 食物环境暴露是食物过敏的危险因素。

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-08-01 DOI: 10.1007/s11882-023-01091-0

Andrew V Turner, Johanna M Smeekens

引用次数: 0

Allergies Come Clean: The Role of Detergents in Epithelial Barrier Dysfunction. 变态反应一清二楚：洗涤剂在上皮屏障功能障碍中的作用。

IF 5.4 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-08-01 Epub Date: 2023-05-26 DOI: 10.1007/s11882-023-01094-x

Benjamin L Wright, Mia Y Masuda, Danna R Ortiz, Adelyn Dao, Blake Civello, Grace C Pyon, Aliviya R Schulze, James A Yiannas, Matthew A Rank, Hirohito Kita, Alfred D Doyle

{"title":"Allergies Come Clean: The Role of Detergents in Epithelial Barrier Dysfunction.","authors":"Benjamin L Wright, Mia Y Masuda, Danna R Ortiz, Adelyn Dao, Blake Civello, Grace C Pyon, Aliviya R Schulze, James A Yiannas, Matthew A Rank, Hirohito Kita, Alfred D Doyle","doi":"10.1007/s11882-023-01094-x","DOIUrl":"10.1007/s11882-023-01094-x","url":null,"abstract":"Purpose of review: The prevalence and incidence of allergic disease have been rising in Westernized countries since the twentieth century. Increasingly, evidence suggests that damage to the epithelium initiates and shapes innate and adaptive immune responses to external antigens. The objective of this review is to examine the role of detergents as a potential risk factor for developing allergic disease.Recent findings: Herein, we identify key sources of human detergent exposure. We summarize the evidence suggesting a possible role for detergents and related chemicals in initiating epithelial barrier dysfunction and allergic inflammation. We primarily focus on experimental models of atopic dermatitis, asthma, and eosinophilic esophagitis, which show compelling associations between allergic disease and detergent exposure. Mechanistic studies suggest that detergents disrupt epithelial barrier integrity through their effects on tight junction or adhesion molecules and promote inflammation through epithelial alarmin release. Environmental exposures that disrupt or damage the epithelium may account for the increasing rates of allergic disease in genetically susceptible individuals. Detergents and related chemical compounds represent possible modifiable risk factors for the development or exacerbation of atopy.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 8","pages":"443-451"},"PeriodicalIF":5.4,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10065170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist. 自身免疫性炎症性眼病:内科医生的临床表现。

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-08-01 DOI: 10.1007/s11882-023-01088-9

Richmond Woodward, Sri Meghana Konda, Dilraj S Grewal

{"title":"Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist.","authors":"Richmond Woodward, Sri Meghana Konda, Dilraj S Grewal","doi":"10.1007/s11882-023-01088-9","DOIUrl":"https://doi.org/10.1007/s11882-023-01088-9","url":null,"abstract":"Purpose of review: Provide a framework for recognizing key symptoms and clinical findings in patients with autoimmune inflammatory eye disease.Recent findings: The most common manifestations of autoimmune inflammatory eye disease are episcleritis, scleritis, uveitis (anterior, intermediate, posterior, and panuveitis), and keratoconjunctivitis sicca. Etiologies can be idiopathic or in association with a systemic autoimmune condition. Referral of patients who may have scleritis is critical for patients presenting with red eyes. Referral of patients who may have uveitis is critical for patients presenting often with floaters and vision complaints. Attention should also be directed to aspects of the history that might suggest a diagnosis of a systemic autoimmune condition, immunosuppression, drug-induced uveitis, or the possibility of a masquerade condition. Infectious etiologies should be ruled out in all cases. Patients with autoimmune inflammatory eye disease may present with ocular or systemic symptoms alone, or in combination. Collaboration with ophthalmologists and other relevant specialists is vital to optimal long-term medical care.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 8","pages":"471-479"},"PeriodicalIF":5.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10010602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Climate Change on Asthma and Allergic-Immunologic Disease. 气候变化对哮喘和过敏性免疫疾病的影响。

IF 5.4 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-08-01 Epub Date: 2023-06-07 DOI: 10.1007/s11882-023-01093-y

Grace Kelly, Osatohamwen I Idubor, Sophie Binney, Paul J Schramm, Maria C Mirabelli, Joy Hsu

{"title":"The Impact of Climate Change on Asthma and Allergic-Immunologic Disease.","authors":"Grace Kelly, Osatohamwen I Idubor, Sophie Binney, Paul J Schramm, Maria C Mirabelli, Joy Hsu","doi":"10.1007/s11882-023-01093-y","DOIUrl":"10.1007/s11882-023-01093-y","url":null,"abstract":"Purpose of review: This review discusses climate change-related impacts on asthma and allergic-immunologic disease, relevant US public health efforts, and healthcare professional resources.Recent findings: Climate change can impact people with asthma and allergic-immunologic disease through various pathways, including increased exposure to asthma triggers (e.g., aeroallergens, ground-level ozone). Climate change-related disasters (e.g., wildfires, floods) disrupting healthcare access can complicate management of any allergic-immunologic disease. Climate change disproportionately affects some communities, which can exacerbate disparities in climate-sensitive diseases like asthma. Public health efforts include implementing a national strategic framework to help communities track, prevent, and respond to climate change-related health threats. Healthcare professionals can use resources or tools to help patients with asthma and allergic-immunologic disease prevent climate change-related health impacts. Climate change can affect people with asthma and allergic-immunologic disease and exacerbate health disparities. Resources and tools are available to help prevent climate change-related health impacts at the community and individual level.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 8","pages":"453-461"},"PeriodicalIF":5.4,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10007651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Use and Teaching of Telemedicine in Allergy/Immunology Training Programs. 远程医疗在过敏/免疫学培训项目中的应用与教学。

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-08-01 DOI: 10.1007/s11882-023-01096-9

Emily Robbins, Kirti Johal, Anjeni Keswani

{"title":"The Use and Teaching of Telemedicine in Allergy/Immunology Training Programs.","authors":"Emily Robbins, Kirti Johal, Anjeni Keswani","doi":"10.1007/s11882-023-01096-9","DOIUrl":"https://doi.org/10.1007/s11882-023-01096-9","url":null,"abstract":"Purpose of review: The use of telemedicine has greatly increased since the onset of the coronavirus disease 2019 (COVID-19) pandemic. This review discusses the types of telemedicine, current telehealth curricula in medical education, and benefits and disadvantages of incorporation of telemedicine into Allergy/Immunology training programs.Recent findings: The majority of Allergists/Immunologists use telemedicine in their clinical practice with leaders in graduate medical education recommending inclusion of telemedicine in training. Fellows-in-training reported that use of telemedicine in Allergy/Immunology training during the pandemic mitigated some concerns for lack of adequate clinical experience. Still, no standardized curriculum for telemedicine training in Allergy/Immunology exists, although curricula from internal medicine and primary care residencies can provide a framework for incorporation of telemedicine training into fellowship. Benefits of telemedicine in Allergy/Immunology training include enhanced immunology training, home environment monitoring, and flexibility to reduce physician burnout while disadvantages include limited physical examination skill building and lack of a standardized curriculum. As telemedicine has been widely accepted in medicine with high patient satisfaction, it is necessary to incorporate a standardized telehealth curriculum in Allergy/Immunology fellowship training, both as a tool for patient care as well as trainee education.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 8","pages":"463-470"},"PeriodicalIF":5.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10066180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Impact of Air Pollution on Atopic Dermatitis. 空气污染对特应性皮炎的影响。

IF 5.5 2区医学

Current Allergy and Asthma Reports Pub Date : 2023-08-01 DOI: 10.1007/s11882-023-01095-w

Austin Lai, Kelly Owens, Surya Patel, Matilda Nicholas

{"title":"The Impact of Air Pollution on Atopic Dermatitis.","authors":"Austin Lai, Kelly Owens, Surya Patel, Matilda Nicholas","doi":"10.1007/s11882-023-01095-w","DOIUrl":"https://doi.org/10.1007/s11882-023-01095-w","url":null,"abstract":"Purpose of review: Atopic dermatitis (AD) remains a dermatological disease that imposes a significant burden on society. Air pollution has previously been linked to both the onset and severity of atopic dermatitis. As air pollution remains a critical environmental factor impacting human health, this review seeks to provide an overview of the relationship between different air pollutants and AD.Recent findings: AD can develop from multiple causes that can be broadly grouped into epidermal barrier dysfunction and immune dysregulation. Air pollution imposes significant health risks and includes a wide variety of pollutant types. AD has been linked to outdoor air pollutants such as particulate matter (PM), volatile organic compounds (VOC), gaseous compounds, and heavy metals. Exposure to indoor pollutants such as tobacco smoke and fungal molds has also been associated with an increased incidence of AD. While different pollutants impact distinct molecular pathways in the cell, they mostly converge on ROS product, DNA damage, and dysregulated T-cell activity and cytokine production. The presented review suggests a strengthening tie between air pollution and AD. It points to opportunities for further studies to clarify, as well as potential therapeutic opportunities that leverage the mechanistic relationships between air pollution and AD.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"23 8","pages":"435-442"},"PeriodicalIF":5.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10065171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0