{"title":"Advanced trauma life support 2025: A brief review of updates","authors":"Akilesh Ramasamy","doi":"10.1016/j.injury.2026.113079","DOIUrl":"10.1016/j.injury.2026.113079","url":null,"abstract":"<div><div>Guidelines and practices in trauma care constantly evolve based on evidence available, and every healthcare provider who treats trauma should be up-to-date in trauma-care concepts. The Eleventh Edition of Advanced Trauma Life Support, released in 2025, contains a complete revamp of the foundational principles of acute trauma care, content design, delivery, and training, based on medical and educational evidence. In this edition, a significant update is the emphasis on control of exsanguinating/major haemorrhage (ABCDE to x-ABCDE where x stands for control of exsanguinating haemorrhage in trauma resuscitation. In addition to damage control resuscitation, some of the significant changes include recommendations for permissive hypotension, limiting crystalloids, early transfusion, neuroprotective focus, and modifications in operational principles in spine motion restriction. Some of these conceptual changes with their rationale are briefly described in this review as an update for any healthcare provider involved in trauma resuscitation.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 113079"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146147345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yin Yang , Yongqing Xu , Jian Shi , Wei Yu , Xiaoqing He , Qixiong Guo , Xinyu Fan
{"title":"Matched comparative study of 3D printed microporous tantalum prosthesis versus autologous bone graft in the final stage of Masquelet induced membrane surgery","authors":"Yin Yang , Yongqing Xu , Jian Shi , Wei Yu , Xiaoqing He , Qixiong Guo , Xinyu Fan","doi":"10.1016/j.injury.2026.113087","DOIUrl":"10.1016/j.injury.2026.113087","url":null,"abstract":"<div><h3>Background</h3><div>Masquelet induced membrane surgery is a viable option for the reconstruction of extensive bone defects. This study aimed to comprehensively compare the clinical efficacy of 3D printed microporous tantalum prosthesis and autologous bone graft in the final stage of Masquelet induced membrane surgery during the treatment of lower extremity fracture-related infections(FRI) with large segmental bone defect.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed the clinical data of 43 patients with large segmental bone defect caused by lower extremity FRI treated with Masquelet induced membrane surgery. Among these, 21 patients were implanted 3D printed microporous tantalum prosthesis (Prosthesis group), while 22 patients were implanted autologous bone graft (Autologous bone group) in the final-stage surgery. Follow-up was conducted for 12 months postoperatively. Clinical efficacy was evaluated using the Paley grade for bone defect healing, Visual analog scale (VAS), Lower extremity functional scale (LEFS), Fernandez-Esteve eschar score, and time to full weight-bearing. The clinical outcomes between the two treatment groups were compared.</div></div><div><h3>Results</h3><div>Postoperatively, the scores of VAS and LEFS significantly improved compared to preoperative values in both groups (all <em>P</em> < 0.001). Compared to the Autologous bone group, the Prosthesis group demonstrated significantly higher LEFS scores and Fernandez-Esteve eschar scores, along with a significantly shorter time to full weight-bearing (all <em>P</em> < 0.05). The complication rate was 19.0% (4/21) in the Prosthesis group and 9.1% (2/22) in the Autologous bone group; there was no statistically significant difference between the two groups (<em>P</em> > 0.05). Patients experiencing complications received effective and targeted interventions.</div></div><div><h3>Conclusion</h3><div>Both implants show remarkable efficacy in the reconstruction of large segmental bone defect caused by lower limb FRI. However, 3D printed microporous tantalum prosthesis exhibits certain advantages over the autologous bone graft in terms of limb function recovery, bone callus growth, and early weight-bearing. However, when using this technique, one should be vigilant about the risk of complications.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 113087"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146147346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: “Clinical and radiological outcome of extended lateral approach via epicondyle osteotomy in complex lateral tibia plateau fractures involving the central and postero-lateral segments”","authors":"Udit Kumar Jayant , Devendra Kumar Chouhan , Ravikiran Vanapalli , Mandeep Singh Dhillon","doi":"10.1016/j.injury.2025.112877","DOIUrl":"10.1016/j.injury.2025.112877","url":null,"abstract":"","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 112877"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145508683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The geometric mismatch: Are we over-stiffening osteoporotic fixation by ignoring plate thickness?","authors":"Shabir A Dhar","doi":"10.1016/j.injury.2025.112975","DOIUrl":"10.1016/j.injury.2025.112975","url":null,"abstract":"","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 112975"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “Incidence of venous thromboembolism following Achilles tendon rupture: Data from the UK-FATE audit”","authors":"Muhammad Awwab","doi":"10.1016/j.injury.2025.112879","DOIUrl":"10.1016/j.injury.2025.112879","url":null,"abstract":"","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 112879"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor: A comparative finite element study of novel design hook plates for fixation of patella fracture","authors":"Leela Kumaran , Sheifali Gupta","doi":"10.1016/j.injury.2025.112873","DOIUrl":"10.1016/j.injury.2025.112873","url":null,"abstract":"","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 112873"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychiatric prognostic models after TBI: What we predict and who we miss","authors":"Hequn Li , Xiaoning Huo","doi":"10.1016/j.injury.2026.113057","DOIUrl":"10.1016/j.injury.2026.113057","url":null,"abstract":"","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 113057"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146047594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanical and clinical performance of acellular allogeneic dermis combined with autologous split-thickness skin grafts for ankle soft tissue defect repair","authors":"Yixin Zhu , Qinghua Lai , Zhiyi Wei , Juntao Cheng","doi":"10.1016/j.injury.2026.113088","DOIUrl":"10.1016/j.injury.2026.113088","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the clinical efficacy, wound healing quality, and functional recovery of a composite grafting technique using acellular dermal matrix (ADM) and autologous split-thickness skin graft (ASTSG) for reconstructing complex ankle soft tissue defects.</div></div><div><h3>Methods</h3><div>A retrospective cohort study included 108 patients with ankle soft tissue defects (≥3 cm²). Patients were divided into an observation group (<em>n</em> = 55, ADM+ASTSG) and a control group (<em>n</em> = 53, pedicled skin flap). Primary outcomes were graft survival, wound healing time, and scar quality (Vancouver Scar Scale). Secondary outcomes included ankle function (range of motion, gait analysis), operative parameters, cost, and histological assessment of neotissue.</div></div><div><h3>Results</h3><div>The ADM+ASTSG group demonstrated a significantly higher graft survival rate (96.80 % vs. 78.22 %, <em>P</em> < 0.05) and superior scar quality at 6 months (VSS total score: 2.3 ± 0.8 vs. 4.7 ± 1.1, <em>P</em> < 0.05). Functional recovery was better, evidenced by greater ankle range of motion and gait symmetry (68.3 ± 5.2 % vs. 59.6 ± 4.8 %, <em>P</em> < 0.05). The technique also resulted in shorter operative time (36.6 ± 6.3 vs. 118.6 ± 11.4 min, <em>P</em> < 0.05) and lower hospitalization costs. Histologically, the ADM group showed more organized collagen fibers and a higher collagen I/III ratio, indicating more mature tissue regeneration.</div></div><div><h3>Conclusion</h3><div>The ADM+ASTSG composite grafting technique promotes high-quality wound healing and functional recovery in ankle soft tissue defects, offering a clinically effective and cost-efficient alternative to traditional flaps. Its ability to support structured tissue regeneration translates into superior scar quality and mechanical adaptability for the dynamic ankle joint.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 113088"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146147696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siffat Ullah , Abdullah Muhammad Abu Bakar , Hussain Ramzan
{"title":"Critical considerations in shock index application for normotensive trauma patients: Limitations and future directions","authors":"Siffat Ullah , Abdullah Muhammad Abu Bakar , Hussain Ramzan","doi":"10.1016/j.injury.2025.112874","DOIUrl":"10.1016/j.injury.2025.112874","url":null,"abstract":"<div><div>This letter addresses the research conducted by Lin et al. regarding the shock index (SI) as an indicator of compensated shock in normotensive trauma cases. We acknowledge the authors' efforts while highlighting significant limitations: overlooked confounding due to cardioactive drugs, survival bias from omitting early fatalities, influences of prehospital fluid resuscitation, and insufficient age-specific SI thresholds. We additionally challenge transfusion as a surrogate for shock and emphasize the variation in injury mechanisms. Suggestions consist of modifications in pharmacovigilance, incorporation of early mortality statistics, and multi-center confirmations with microcirculatory outcomes.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 4","pages":"Article 112874"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Social deprivation results in longer perioperative admission and decreased rates of home discharge after distal femur fracture","authors":"Xiaojing Bai, Menghui Gao","doi":"10.1016/j.injury.2025.112863","DOIUrl":"10.1016/j.injury.2025.112863","url":null,"abstract":"","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"57 3","pages":"Article 112863"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145477294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}