Daniel Coelho de Carvalho, Vandilson Rodrigues, Fernanda Belo da Fonseca Josino, Rafael Soares Diniz, Letícia Machado Gonçalves
{"title":"Comparing patient satisfaction and pain control between vibration and topical anesthesia during botulinum toxin A injections: a randomized, double-blind, split-face clinical trial.","authors":"Daniel Coelho de Carvalho, Vandilson Rodrigues, Fernanda Belo da Fonseca Josino, Rafael Soares Diniz, Letícia Machado Gonçalves","doi":"10.1080/14764172.2026.2652488","DOIUrl":"https://doi.org/10.1080/14764172.2026.2652488","url":null,"abstract":"<p><p>This study aimed to evaluate pain levels, patient satisfaction, and preferences for different anesthetic techniques during the cosmetic application of botulinum toxin A in the upper third of the face. A randomized, double-blind, split-face clinical trial was conducted with 100 women undergoing esthetic procedures for facial wrinkle reduction. Patients were assigned to three groups: vibratory anesthesia versus placebo (Group I), topical anesthesia versus placebo (Group II), and vibratory anesthesia versus topical anesthesia (Group III). Pain levels were assessed using the visual analog scale (VAS). Patients identified the side with better pain control, expressed satisfaction, and provided recommendations for each technique. Group I (vibration 5.02 ± 2.56 vs. placebo 6.00 ± 2.75, <i>p</i> = .034), Group II (topical anesthetic 4.69 ± 2.45 vs. placebo 5.50 ± 2.38, <i>p</i> = .039), and Group III (topical anesthetic 4.89 ± 2.29 vs. vibration 6.06 ± 2.22, <i>p</i> = .048). While satisfaction levels showed no statistically significant differences between techniques, topical anesthesia in Group III received the highest recommendations (<i>p</i> = .010). This study suggests that topical anesthesia and vibratory stimulation both offer small-to-medium analgesic benefits over placebo during BoNT-A injections. Despite comparable satisfaction scores, patients preferred topical anesthesia for future use.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-8"},"PeriodicalIF":1.3,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative efficacy of 1064 nm Q-Switched Nd:YAG laser and microneedling in treating atrophic acne scars: a retrospective study.","authors":"Ayris Ozturk, Ayda Acar, İlgen Ertam Sagduyu","doi":"10.1080/14764172.2026.2651542","DOIUrl":"https://doi.org/10.1080/14764172.2026.2651542","url":null,"abstract":"<p><strong>Introduction: </strong>Acne scars, stemming from collagen irregularities in acne vulgaris, pose psychosocial challenges. This study evaluates the efficacy and safety of 1064 nm Q-switched Nd:YAG laser (QSNL) and microneedling for atrophic acne scars.</p><p><strong>Methods: </strong>A retrospective study at Ege University included 30 patients with moderate-to-severe atrophic facial acne scars. Patients received three monthly sessions of either QSNL or microneedling from September 2020 to April 2022. Outcome measures included scar size reduction, Goodman and Baron scales (GBQN), Patient Healing Assessments (PHA), Investigator's Global Assessments (IGA), Dermatology Life Quality Index (DLQI), and side effects, evaluated at baseline, 1 month, and 4 months.</p><p><strong>Results: </strong>Scar sizes decreased by 52.63% and 57.14% post-laser, and 62.99% and 69.23% post-microneedling at 1 and 4 months. GBQN scores declined by 28.46% and 38.05% for laser, and 27.18% and 34.38% for microneedling. IGA and PHA improvements were significant, with DLQI scores decreased by 58.28% and 50% for laser and microneedling, respectively. Both treatments proved effective with minimal side effects, with microneedling causing mild erythema and no persistent dyspigmentation or infection.</p><p><strong>Conclusion: </strong>QSNL and microneedling effectively and safely treat atrophic acne scars, improving scar dimensions, quality of life, and satisfaction. Long-term collagen remodeling highlights the importance of follow-up.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-15"},"PeriodicalIF":1.3,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrograde approach to mid-face thread lift with reverse temporal vectors: an innovative insight into the conventional approach.","authors":"Indu Ballani, Aanchal Bansal","doi":"10.1080/14764172.2026.2651544","DOIUrl":"https://doi.org/10.1080/14764172.2026.2651544","url":null,"abstract":"<p><p>The retrograde approach to mid-face thread lift, utilizing reverse temporal vectors, offers an innovative advancement in minimally invasive facial rejuvenation. This study evaluates its efficacy and safety in 20 female patients aged 30-60 years presenting with moderate midface ptosis but minimal jowling and neck laxity. The technique involves inserting poly L-lactide-co-ε-caprolactone bi-directional threads into anchor points near the zygomatic body, leveraging the structural support of ligaments and minimizing neurovascular risks. Immediate post-procedure results revealed significant improvements, with lateral mouth angles elevated by 0.3-0.5 cm and medial cheek points by 0.2-0.3 cm. Patient satisfaction scores (PSS) were consistently high (2-3). During the one-month follow-up, additional gains of 0.1-0.2 cm were noted at the same points, alongside enhanced skin quality and firmness. At six months, outcomes remained stable for patients without adjunctive procedures, maintaining high PSS scores (2-3). The study reinforces the retrograde reverse-vector method as a safe, effective option for midface rejuvenation. Future research should explore its long-term benefits, optimization for varying patient profiles, and integration with other aesthetic modalities for enhanced results. This innovation exemplifies progress in minimally invasive solutions for age-related facial concerns.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-6"},"PeriodicalIF":1.3,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoli Zhang, Hedan Yang, Yiping Ge, Yin Yang, Tong Lin
{"title":"Comparison of efficacy and safety of fractional 1064 nm picosecond laser and low-fluence Q-switched Nd:YAG laser in the treatment of melasma.","authors":"Xiaoli Zhang, Hedan Yang, Yiping Ge, Yin Yang, Tong Lin","doi":"10.1080/14764172.2026.2644196","DOIUrl":"https://doi.org/10.1080/14764172.2026.2644196","url":null,"abstract":"<p><p>Melasma is a persistent and recurrent condition that remains difficult to manage effectively. Both fractional 1064 nm picosecond Nd:YAG (PSNY) and low-fluence Q-switched Nd:YAG (QSNY) lasers have been applied in treatment, yet there is currently insufficient data to compare their efficacy and safety. This retrospective study evaluated 99 female patients with melasma, including 54 treated with PSNY laser and 45 with QSNY laser. Each patient received two to five laser sessions at 2-4-week intervals. Clinical efficacy was evaluated by the modified Melasma Area and Severity Index (mMASI) at baseline, as well as four weeks following the second and fifth treatment sessions, with adverse events carefully documented. The PSNY laser produced a mean mMASI reduction of 23.7% and 40.7% after two and five sessions, respectively, while QSNY treatment achieved reductions of 9.8% and 29.5%. Although both modalities were safe and effective, PSNY laser demonstrated faster clinical improvement and required lower energy fluence. Post-inflammatory hyperpigmentation occurred in 7.4% of PSNY-treated patients and 13.3% of QSNY-treated patients, with no significant difference between groups. In conclusion, fractional PSNY laser therapy provides a rapid, safe, and effective alternative to QSNY laser for managing melasma.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-6"},"PeriodicalIF":1.3,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcele Frederico Arouca, Maristela Maia Lobo, Patrícia Moreira de Freitas, Luiz Felipe Palma, Luana de Campos
{"title":"Varicella-zoster virus expression following fractional Thulium laser treatment for skin rejuvenation: the first case report.","authors":"Marcele Frederico Arouca, Maristela Maia Lobo, Patrícia Moreira de Freitas, Luiz Felipe Palma, Luana de Campos","doi":"10.1080/14764172.2026.2644194","DOIUrl":"https://doi.org/10.1080/14764172.2026.2644194","url":null,"abstract":"<p><p>The use of high-power lasers for facial rejuvenation has been growing every year. In particular, the Thulium laser in non-ablative mode has gained prominence due to its safety, postoperative comfort, and wide clinical indication. This report details the first documented case of a varicella-zoster virus expression following the use of a non-ablative fractional 1927 nm Thulium laser for facial skin aging and pigmentated lesions. The treatment proposed involved a combination of phototherapies as an adjunctive local strategy, alongside systemic acyclovir therapy. In nine days, herpetic lesions and skin areas with altered sensory function were no longer present. Varicella-zoster virus expression should be considered following aesthetic skin treatments with fractional Thulium laser, and the need for prophylaxis with antiviral agents may be appropriate for certain cases. Moreover, the combination of phototherapies proposed herein seemed to be beneficial for accelerating the resolution of such a condition.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-4"},"PeriodicalIF":1.3,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lluís Corbella-Bagot, Agustí Toll-Abelló, Paula Aguilera-Peiró, Alejandra Sandoval-Clavijo
{"title":"The role of fractional CO<sub>2</sub> laser therapy in post-surgical skin cancer scarring.","authors":"Lluís Corbella-Bagot, Agustí Toll-Abelló, Paula Aguilera-Peiró, Alejandra Sandoval-Clavijo","doi":"10.1080/14764172.2026.2633119","DOIUrl":"https://doi.org/10.1080/14764172.2026.2633119","url":null,"abstract":"<p><p>Scars from skin cancer surgery impact patients' quality of life. In recent years, fractional CO<sub>2</sub> (fCO<sub>2</sub>) laser has been used for scar improvement. A single-center retrospective study (<i>n</i> = 22) was conducted to evaluate the safety and efficacy of the fCO<sub>2</sub> laser in improving the aesthetic outcome of post-surgical skin cancer scars, using the validated Vancouver Scar Scale (VSS). We obtained a mean VSS reduction of 44.5% and an absolute decrease of 2.77 points (<i>p</i> < .001). Statistically significant improvements were observed in all VSS parameters except for pigmentation. No significant correlation was found between time since surgery and reduction in VSS. Fractional CO<sub>2</sub> laser is a safe and effective approach for improving surgical scars following skin cancer treatment. Its efficacy is not limited to early scars.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-5"},"PeriodicalIF":1.3,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lê Thị Thu Hải, Bàn Nguyễn Thị Hằng, L Ali, F Al-Niaimi
{"title":"Bilateral nevus of Ota series treated with picosecond laser.","authors":"Lê Thị Thu Hải, Bàn Nguyễn Thị Hằng, L Ali, F Al-Niaimi","doi":"10.1080/14764172.2026.2624409","DOIUrl":"https://doi.org/10.1080/14764172.2026.2624409","url":null,"abstract":"<p><strong>Background: </strong>Nevus of Ota (NO) \"oculodermal melanocytosis\" is prevalent in Asians. Bilateral nevus of Ota (BNO) is a rare condition and comprises 5% of the cases seen. Picosecond laser (PS) is useful in treating various cutaneous benign pigmentary disorders including NO. We analyzed the clinical data on BNO in Vietnamese patients and evaluated the efficacy of treatment of the 1064 nm Nd:YAG picosecond laser (PSNY).</p><p><strong>Subjects and methods: </strong>Twenty-nine Vietnamese patients (ages 2-67 years, mean 23.36 ± 17.5) with BNO received at least 3 treatment sessions with 1064-nm PSNY (4-5 mm spot size; 1.5-2.4J/cm<sup>2</sup>, 4-week intervals). Improvement was documented through serial photographs that were taken at baseline (T0), after 4 weeks of the 3<sup>rd</sup> session (T1), 6<sup>th</sup> session (T2), 9<sup>th</sup> session (T3), and more than 10 sessions (T4). Response to the treatment was graded based on a 5-point grading scale.</p><p><strong>Results: </strong>The participants were predominantly female (23 females, 6 males). Sclera, nasal mucosa, and pharyngeal NO lesions were observed in 24 patients (51.7%, 69%, and 6.9%, respectively). Two cases (6.89%) had lesions combined with Port-Wine-Stains. In the majority of cases, more than two branches of the trigeminal nerve were involved (89.66%). Onset of the lesions at <10 years old was 69% and involvement of more than two branches of the trigeminal nerve in these patients was 89.66%. Overall, 100% of patients demonstrated an improvement of the BNO lesions following treatment. A total of 88.9% of patients demonstrated a score compatible with good improvement to complete clearance after 9 treatment sessions on the treatment scoring scale. No severe adverse events or complications were observed. The 1064-nm PSNY laser has the potential to achieve faster clearance for treating dermal pigmentary disorders in Asians. To our knowledge, this is the largest reported series of BNO treated with a laser.</p><p><strong>Conclusion: </strong>Our results suggest that 1064-nm PSNY laser treatment is efficacious and an appropriate therapeutic modality for the treatment of BNO with minimal downtime and minimal adverse side effects.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-11"},"PeriodicalIF":1.3,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azin Tahvildari, Maryam Daneshpazhooh, Ifa Etesami, Pedram Noormohamdpour, Hamidreza Mahmoudi
{"title":"Long-pulsed Erbium: YAG laser for the treatment of an adult colloid milium: a case report and review of the literature.","authors":"Azin Tahvildari, Maryam Daneshpazhooh, Ifa Etesami, Pedram Noormohamdpour, Hamidreza Mahmoudi","doi":"10.1080/14764172.2026.2620153","DOIUrl":"https://doi.org/10.1080/14764172.2026.2620153","url":null,"abstract":"<p><p>Colloid milium (CM) is a rare degenerative deposition skin disorder known by multiple small, domed, flesh-colored papules that may coalesce into large plaques or highly disfiguring nodules. CM frequently involves sun-exposed body areas, such as the face and dorsal hands. Currently, there is no single effective treatment for CM. Herein, we present a case of adult colloid milium (ACM) with lesions around his nasolabial fold and perioral region who was successfully treated with long-pulsed Erbium: YAG laser with no scarring, textural changes, pigment alterations, or evidence of clinical recurrence at the 3 years follow-up. A systematic search was conducted in PubMed and Scopus until 25 Jan 2025, evaluating all studies with treatment procedure comprehension for ACM. CO2 laser effectively ablated the lesions, while increasing the risk of thermal damage and scarring. Dermabrasion showed favorable efficacy; however, the authors did not specify whether textural changes or pigmentation disorders occurred. Non-Ablative fractional laser has minimal side effects, while multiple sessions are required for satisfactory results. The long-pulsed Er: YAG laser offers high precision and minimal invasiveness, however, its shallow penetration may require multiple sessions for deeper lesions. Long-pulsed Er: YAG laser should be considered an effective treatment for facial CM lesions. Future studies should compare laser types, optimize parameters, and explore adjunct therapies to improve outcomes.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-4"},"PeriodicalIF":1.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146101143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding delayed-onset inflammatory responses (DIRs) to hyaluronic acid fillers: a comprehensive literature review and retrospective cohort study.","authors":"M Emin Akyol, Thomas Rustemeyer, Tom Decates","doi":"10.1080/14764172.2026.2617549","DOIUrl":"https://doi.org/10.1080/14764172.2026.2617549","url":null,"abstract":"<p><p>This study aims to investigate the underlying mechanisms and triggers of delayed-onset inflammatory responses DIRs after hyaluronic acid (HA) fillers injections. The literature review included articles on DIRs following HA filler treatments and identified immunological triggers, bacterial contamination, and filler degradation as key factors contributing to DIRs. Additionally, patient data were analyzed from patients treated for DIRs and showed possible immune activation events prior to DIRs included flu-like symptoms. This study underscores the complexity of DIRs following HA filler treatments and the need for transparency from manufacturers. Comprehensive ingredient data are crucial to better understand DIRs and ensure patient safety.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-13"},"PeriodicalIF":1.3,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lasers and ultrasound in Aesthetic medicine: a hybrid review of efficacy, safety, and future directions.","authors":"Alexandre Rebelo-Marques","doi":"10.1080/14764172.2026.2617546","DOIUrl":"https://doi.org/10.1080/14764172.2026.2617546","url":null,"abstract":"<p><p>Energy-based devices, especially lasers and ultrasound (HIFU/MFU-V), have transformed esthetic medicine, yet evidence remains scattered. This hybrid review couples systematic retrieval of quantitative studies with expert synthesis to define areas of strength and caution. Searches of MEDLINE, Embase, Scopus, and Cochrane captured RCTs, observational series, and meta-analyses on laser- and ultrasound-guided interventions. Efficacy, downtime, satisfaction, and complications were extracted and tabulated, focusing on Fitzpatrick IV-VI skin, BMI sub-groups, and emerging AI-guided planning.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"1-14"},"PeriodicalIF":1.3,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146069076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}