Michael Gold, Ungku Mohd Shahrin Mohd Zaman, Vinay Chouksey, Mahesh Gosavi
{"title":"评估一种仿生肽溶液对供体头皮再生的效果,并在FUE头发移植过程中作为毛囊移植物的储存介质。","authors":"Michael Gold, Ungku Mohd Shahrin Mohd Zaman, Vinay Chouksey, Mahesh Gosavi","doi":"10.1080/14764172.2025.2468499","DOIUrl":null,"url":null,"abstract":"<p><p>Androgenetic alopecia significantly affects individuals' quality of life, creating a need for better therapeutic strategies. Hair transplant surgery plays a key role in treating hair loss, with adjuncts like PRP and meso-cocktails explored to enhance results and procedure longevity. A prospective, single-blind study involved 112 males aged 25-50 years with Norwood-Hamilton grade IV-VI alopecia. Patients were randomly divided into two groups receiving different transplant methods. In Stage I, hair condition was evaluated, and QR678 Neo® was administered intradermally in Group A. Stage II involved hair transplantation surgery with diluted QR678 Neo® for graft preservation. Post-transplantation (Stage III) included additional QR678 Neo® administration in Group A. Evaluation methods consisted of global photographic assessment and videomicroscopy to measure hair growth and density. Group A (QR678 Neo®) demonstrated significant improvements in regrowth, density, and shaft diameter compared to Group B (conventional transplant). By Stage III, Group A had higher Global Photographic Assessment scores (8.87) and terminal hair count (181.02), with statistically significant differences (<i>p</i> < .001). The study suggests that QR678 Neo® improves outcomes and offers a promising treatment option for androgenetic alopecia.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"27 3","pages":"64-70"},"PeriodicalIF":1.2000,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of the efficacy of a biomimetic peptide solution for rejuvenation of donor scalp and as storage media for hair follicle grafts during FUE hair transplantation.\",\"authors\":\"Michael Gold, Ungku Mohd Shahrin Mohd Zaman, Vinay Chouksey, Mahesh Gosavi\",\"doi\":\"10.1080/14764172.2025.2468499\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Androgenetic alopecia significantly affects individuals' quality of life, creating a need for better therapeutic strategies. Hair transplant surgery plays a key role in treating hair loss, with adjuncts like PRP and meso-cocktails explored to enhance results and procedure longevity. A prospective, single-blind study involved 112 males aged 25-50 years with Norwood-Hamilton grade IV-VI alopecia. Patients were randomly divided into two groups receiving different transplant methods. In Stage I, hair condition was evaluated, and QR678 Neo® was administered intradermally in Group A. Stage II involved hair transplantation surgery with diluted QR678 Neo® for graft preservation. Post-transplantation (Stage III) included additional QR678 Neo® administration in Group A. Evaluation methods consisted of global photographic assessment and videomicroscopy to measure hair growth and density. Group A (QR678 Neo®) demonstrated significant improvements in regrowth, density, and shaft diameter compared to Group B (conventional transplant). By Stage III, Group A had higher Global Photographic Assessment scores (8.87) and terminal hair count (181.02), with statistically significant differences (<i>p</i> < .001). The study suggests that QR678 Neo® improves outcomes and offers a promising treatment option for androgenetic alopecia.</p>\",\"PeriodicalId\":54852,\"journal\":{\"name\":\"Journal of Cosmetic and Laser Therapy\",\"volume\":\"27 3\",\"pages\":\"64-70\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-04-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cosmetic and Laser Therapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/14764172.2025.2468499\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cosmetic and Laser Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/14764172.2025.2468499","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Evaluation of the efficacy of a biomimetic peptide solution for rejuvenation of donor scalp and as storage media for hair follicle grafts during FUE hair transplantation.
Androgenetic alopecia significantly affects individuals' quality of life, creating a need for better therapeutic strategies. Hair transplant surgery plays a key role in treating hair loss, with adjuncts like PRP and meso-cocktails explored to enhance results and procedure longevity. A prospective, single-blind study involved 112 males aged 25-50 years with Norwood-Hamilton grade IV-VI alopecia. Patients were randomly divided into two groups receiving different transplant methods. In Stage I, hair condition was evaluated, and QR678 Neo® was administered intradermally in Group A. Stage II involved hair transplantation surgery with diluted QR678 Neo® for graft preservation. Post-transplantation (Stage III) included additional QR678 Neo® administration in Group A. Evaluation methods consisted of global photographic assessment and videomicroscopy to measure hair growth and density. Group A (QR678 Neo®) demonstrated significant improvements in regrowth, density, and shaft diameter compared to Group B (conventional transplant). By Stage III, Group A had higher Global Photographic Assessment scores (8.87) and terminal hair count (181.02), with statistically significant differences (p < .001). The study suggests that QR678 Neo® improves outcomes and offers a promising treatment option for androgenetic alopecia.
期刊介绍:
A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment.
The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy.
Features include:
-Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing
-Use of lasers and other light sources for cosmetic and dermatological treatment
-Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities
-Topical treatments
-Practical tips and safety issues