Journal of Dermatology最新文献

{"title":"A case of lupus erythematosus-like eruption under pembrolizumab administration","authors":"Yurie Matsuura, Kento Mizutani, Ayaka Ichikawa, Yasutaka Tono, Hiroki Oka, Makoto Kondo, Koji Habe, Toshiro Mizuno, Ayako Nakajima, Keiichi Yamanaka","doi":"10.1111/1346-8138.17559","DOIUrl":"10.1111/1346-8138.17559","url":null,"abstract":"","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 4","pages":"e288-e289"},"PeriodicalIF":2.9,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous zosteriform endometrial cancer metastasis","authors":"Wangxiang Luo,&nbsp;Xianhong Yang,&nbsp;Yunlin Ren,&nbsp;Xiaohua Tao,&nbsp;Wei Lu","doi":"10.1111/1346-8138.17536","DOIUrl":"10.1111/1346-8138.17536","url":null,"abstract":"<p>A 58-year-old woman sought care for painful skin papules and blisters on her right lower extremity, ongoing for a month. Initially diagnosed with herpes zoster, she received no relief from famciclovir or acyclovir treatments. The lesions spread to her thighs, manifesting as itchy, tingling spots. With a history of poorly differentiated endometrial cancer for 11 years, she had undergone radical surgery and multiple chemotherapy regimens. Systemic examination revealed left cervical lymph node enlargement. Skin inspection showed swelling and redness with bumps on her right lower leg and left thigh base (referenced in Figure 1a,b). A thigh biopsy showed tumor cells arrayed among dermal collagen in various sizes with intense chromatin and clear nuclear division (referenced in Figure 1c,d). The dermal collagen was markedly sclerotic with few inflammatory cells. Immunohistochemistry was positive for P53, EMA, and PAX8, and D2-40 staining indicated lymphatic infiltration by tumor cells. She was diagnosed with cutaneous metastasis from poorly differentiated endometrial adenocarcinoma.</p><p>Cutaneous metastasis from carcinoma is a rare event in the spread of cancer, seen in 0.7%–9% of metastatic cases. It is even rarer in endometrial cancer, with an incidence of less than 0.8%.<span>¹</span> Zosteriform metastasis in skin cancer is a rare phenomenon linked to malignancies such as lung, breast, and gastric cancers, and melanoma. It typically manifests in a band-like pattern, often associated with pain, indicating disease progression and correlating with the primary tumor's location.<span>²</span></p><p>In this case, the patient was diagnosed with endometrial cancer. When skin metastasis was subsequently discovered, the patient had already entered the late stage of malignant tumor treatment, with a poor prognosis. Therefore, when patients with pre-existing endometrial cancer suddenly present with new skin lesions, such as shingles, they need to be alert to the possibility of skin metastasis.</p><p>None declared.</p>","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 1","pages":"e1-e2"},"PeriodicalIF":2.9,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1346-8138.17536","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Automatic evaluation of nail psoriasis severity index using deep learning algorithm”","authors":"","doi":"10.1111/1346-8138.17556","DOIUrl":"10.1111/1346-8138.17556","url":null,"abstract":"<p>Paik K, Kim BR, Youn SW. Automatic evaluation of nail psoriasis severity index using deep learning algorithm. <i>J Dermatol</i> 2024 Oct;51:1310–1317.</p><p>We apologize for this error.</p>","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 1","pages":"187"},"PeriodicalIF":2.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1346-8138.17556","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educational video assistance in shared decision-making for psoriasis: Effectiveness and outcomes","authors":"Sheng-Wen Liu,&nbsp;Shou En Wu,&nbsp;Yi-Hsien Chen,&nbsp;Chen-Yeu Soong,&nbsp;Chien-Ping Chiang,&nbsp;Wei-Ming Wang,&nbsp;Chih-Tsung Hung","doi":"10.1111/1346-8138.17550","DOIUrl":"10.1111/1346-8138.17550","url":null,"abstract":"<p>Psoriasis is a chronic inflammatory skin condition associated with significant comorbidities that impact quality of life. Effective patient engagement through shared decision-making (SDM) is crucial for optimal management. This study aimed to evaluate the effectiveness of adding clinician-created educational videos in enhancing patient knowledge and engagement during SDM for psoriasis treatment. Forty-eight patients with moderate to severe psoriasis participated in this single-center study. After reading an educational pamphlet, patients took a knowledge assessment test. Subsequently, they watched an educational video and completed a second test using the same questions. Feedback questionnaires on the video and the SDM process were also administered. Paired <i>t</i> tests revealed that postpamphlet plus video test scores (mean ± SD: 86.25 ± 17.58) were significantly higher than postpamphlet scores (72.08 ± 26.33, <i>p</i> &lt; 0.0001). Older patients, in particular, showed greater improvement in comprehension after watching the video. Descriptive analysis of the feedback questionnaire on the video indicated strong agreement (average score: 4.240 ± 0.816 on a five-point Likert scale) regarding its greater effectiveness compared with the pamphlet in aiding SDM. Patients also rated the video-assisted SDM process positively (average score: 4.521 ± 0.5443 on a five-point Likert scale), highlighting increased trust and improved communication with healthcare providers. These findings underscore the value of video-assisted SDM in patient education and decision-making processes, potentially improving treatment outcomes and patient satisfaction in dermatologic care.</p>","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 2","pages":"337-343"},"PeriodicalIF":2.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142718017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cheilitis granulomatosa successfully treated by ustekinumab","authors":"Masaru Honma,&nbsp;Hiroyoshi Nozaki","doi":"10.1111/1346-8138.17555","DOIUrl":"10.1111/1346-8138.17555","url":null,"abstract":"","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 4","pages":"e284-e285"},"PeriodicalIF":2.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous lupus erythematosus following immunoglobulin therapy in dermatomyositis","authors":"Eaman Alhassan,&nbsp;Stratos Christianakis,&nbsp;Brittney DeClerck,&nbsp;Ashley B. Crew","doi":"10.1111/1346-8138.17553","DOIUrl":"10.1111/1346-8138.17553","url":null,"abstract":"<p>A 57-year-old woman with a remote history of follicular lymphoma in remission, treated with rituximab with subsequent diagnosis of hypogammaglobulinemia, presented to the Rheumatology-Dermatology clinic for evaluation of an autoimmune disease. The patient reported experiencing rash, myalgias, and proximal muscle weakness for 3 months. Physical examination was remarkable for poikiloderma over the neck and chest (V-sign), upper back (shawl sign), upper arms (sleeve sign), and lateral thighs (Holster sign). She had normal muscle strength. Laboratory work-up demonstrated normal complete blood count, comprehensive metabolic panel, creatine kinase, and aldolase levels. A myositis-specific antibody panel and antinuclear antibody tests were negative. The patient was diagnosed with amyopathic dermatomyositis. Because of her lymphoma history and skin-predominant presentation, intravenous immunoglobulin (Ig) therapy was administered. Three days after receiving the Ig therapy, the patient developed distinct, well-defined, violaceous, juicy appearing plaques on her face, chest, abdomen (Figure 1a), back (Figure 1b), and arms. Ig therapy was held. Skin biopsy of the new lesions showed interface dermatitis (Figure 1c) with increased dermal mucin and karyorrhectic debris consistent with discoid lupus erythematosus. Oral and topical corticosteroids were added with improvement in her skin lesions (Figure 1d).</p><p>A causative link between Ig G treatment and cutaneous lupus erythematosus has been reported in patients receiving Ig treatment for chronic inflammatory demyelinating polyneuropathy.<span>^{1, 2}</span> The rash has been reported to improve after discontinuing Ig treatment or switching to another Ig brand. Van der Molen et al. reported the possible presence of Sjögren's-syndrome-related antigen (SSA) antibodies in Ig preparations.<span>³</span> While the mechanism of induction of cutaneous lupus erythematosus in patients being treated with Ig therapy is not well understood, one hypothesis is that the presence of SSA antibodies in Ig therapy may induce cutaneous lupus in a manner similar to cutaneous changes in neonatal lupus.</p><p>The authors declare no conflict of interest related to this work.</p>","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 2","pages":"e143-e144"},"PeriodicalIF":2.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1346-8138.17553","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in RASA1 and EPHB4 in Chinese patients with capillary malformation-arteriovenous malformation","authors":"Qin Zeng,&nbsp;Wenmin Lu,&nbsp;Ying Ye,&nbsp;Ming Li,&nbsp;Hongsong Ge,&nbsp;Qiaoyu Cao,&nbsp;Wei He,&nbsp;Cheng Zhang,&nbsp;Wei Song","doi":"10.1111/1346-8138.17549","DOIUrl":"10.1111/1346-8138.17549","url":null,"abstract":"<p>Capillary malformation-arteriovenous malformation (CM-AVM) is a genetic condition predominantly attributed to variations in the <i>RASA1</i> or <i>EPHB4</i> genes. We identified three genetic variations: a variation in the RASA1 (c.2603+1G&gt;A) and two novel variations in the EPHB4 (c.53-2A&gt;G and c.2222T&gt;C), expanding the spectrum of variants associated with CM-AVM. Additionally, we found that the presence of EPHB4 variations in these two families, alongside a documented history of Bier spots, highlights the impact of genetic factors on disease phenotype. We also conducted 595 nm pulsed dye laser therapy on the proband 2, and observed that facial telangiectasia was significantly reduced after the laser treatment. We aim to enhance the understanding of the disease through case studies of three families.</p>","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 2","pages":"377-382"},"PeriodicalIF":2.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142694081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital papillary adenocarcinoma detected human papillomavirus type 42 genome: A case report","authors":"Mizuki Hatakeyama,&nbsp;Sayuri Sato,&nbsp;Kohei Horimoto,&nbsp;Junji Kato,&nbsp;Takafumi Kamiya,&nbsp;Hisashi Uhara","doi":"10.1111/1346-8138.17548","DOIUrl":"10.1111/1346-8138.17548","url":null,"abstract":"","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 4","pages":"e282-e283"},"PeriodicalIF":2.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142694079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of notalgia paresthetica presenting as an ulcer successfully treated with gabapentin","authors":"Cheney Jianlin Wong,&nbsp;Harumi Ochi,&nbsp;Wei Liang Koh","doi":"10.1111/1346-8138.17558","DOIUrl":"10.1111/1346-8138.17558","url":null,"abstract":"","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 1","pages":"e3-e4"},"PeriodicalIF":2.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142694077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of non-IgA vasculitis: Demographic, clinical, and treatment-related features in a retrospective analysis of 28 biopsy-confirmed cases from a German university hospital","authors":"Inga Hansen-Abeck,&nbsp;Alessandra Rünger,&nbsp;Lisa Piepke,&nbsp;Julian Kött,&nbsp;Anna Giordano-Rosenbaum,&nbsp;Anne Menz,&nbsp;Finn Abeck,&nbsp;Stefan W. Schneider","doi":"10.1111/1346-8138.17545","DOIUrl":"10.1111/1346-8138.17545","url":null,"abstract":"<p>Non-IgA vasculitis is a rare disease that belongs to the group of small-vessel vasculitides. Due to nomenclature and classification changes introduced in 2018, there are few published data under this name. The aim of this study is to characterize non-IgA vasculitis as an independent vasculitis entity in terms of demographic, clinical, and treatment-related features. A retrospective data analysis of patients with biopsy-confirmed non-IgA vasculitis treated at the Department of Dermatology at the University Medical Center Hamburg-Eppendorf between January 1, 2018, and December 31, 2022, was performed. A total of 28 patients with non-IgA vasculitis were included; 53.6% (15/28) were women and 42.9% (12/28) were older than 71 years. Previous infection as a possible triggering factor was found in 42.6% (12/28) of the cases. Palpable purpura was the most common skin finding (78.6%, 22/28) and 28.6% patients (8/28) had skin lesions above the waist. On direct immunofluorescence, C3 (89.3%, 25/28) was the most frequent deposition, followed by fibrinogen (71.4%, 20/28) and IgM (53.6%, 15/28). Hospitalization was required in 85.7% (24/28), with a mean hospital stay of 9.4 ± 4.1 days. No fatal courses were reported. This study is the first characterization of non-IgA vasculitis based on patient cases from Germany and contributes to a better understanding of non-IgA vasculitis as an independent entity. Non-IgA vasculitis primarily affects older patients of both sexes, with most cases having an identifiable trigger. Our results indicate that cutaneous manifestations often extend beyond the lower legs. Treatment is usually required in the inpatient setting and requires a longer stay than other dermatological conditions. With proper treatment, the disease is not expected to be fatal.</p>","PeriodicalId":54848,"journal":{"name":"Journal of Dermatology","volume":"52 1","pages":"43-49"},"PeriodicalIF":2.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1346-8138.17545","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}