Journal of Hospital Infection最新文献

{"title":"Infection prevention and control in burns services: guidance from the Healthcare Infection Society.","authors":"P A Jumaa, L Teare, P N Hoffman, A E Young, S Smailes, V Edwards-Jones, C Thomas, L S P Moore, S Booth, M A Mugglestone, N S Moiemen","doi":"10.1016/j.jhin.2025.06.008","DOIUrl":"https://doi.org/10.1016/j.jhin.2025.06.008","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative serum amyloid A as a primary marker in a predictive model for ventilator-associated pneumonia in elderly patients with acute ischaemic stroke undergoing endovascular therapy with general anaesthesia.","authors":"Xuerong Zhang, Xueying Yang, Qiong Zhao","doi":"10.1016/j.jhin.2025.06.015","DOIUrl":"https://doi.org/10.1016/j.jhin.2025.06.015","url":null,"abstract":"<p><strong>Background: </strong>The risk factors associated with ventilator-associated pneumonia (VAP) in acute ischaemic stroke (AIS) patients who have undergone endovascular therapy have been primarily reported as clinical-related parameters.</p><p><strong>Aim: </strong>This study aims to combine clinical parameters with inflammatory biomarkers to identify VAP-related risk factors and develop a predictive model.</p><p><strong>Methods: </strong>A total of 564 AIS patients were recruited and divided into the training set (n = 395) and the validation set (n = 169). The least absolute shrinkage and selection operator (LASSO), univariate and multivariate logistic regression analyses were utilized to examine the independent risk factors or biomarkers associated with VAP.</p><p><strong>Findings: </strong>We identified four VAP-associated risk factors or biomarker in AIS patients, consisting of thrombolysis in cerebral infarction (TICI) score (0-IIa) (OR = 4.528; 95% CI: 2.249-9.119; P < 0.001), admission national Institute of Health stroke scale (NIHSS) (OR=1.330; 95% CI: 1.217-1.453; P<0.001), neutrophil lymphocyte ratio (NLR) (OR=2.179; 95% CI: 1.312-3.618; P=0.003), and postoperative serum amyloid A (SAA) (OR=1.194; 95% CI: 1.146-1.244; P<0.001). This predictive model demonstrated robust performance and stability, with an AUC of 0.926 (95% CI: 0.899-0.953) in the training set and 0.937 (95% CI: 0.897-0.977) in the validation set. Notably, using the machine learning algorithm Random Forest for feature importance ranking, postoperative SAA emerged as the most critical predictor of VAP.</p><p><strong>Conclusion: </strong>The predictive model has good predictive value for VAP. Postoperative SAA may serve as a rapid diagnostic biomarker for predicting VAP.</p>","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing infection prevention and control guidelines for healthcare professionals in the Netherlands: an evaluation of the process.","authors":"Annelotte Sussenbach, Haitske Graveland, Andreas Voss, Bart Versteeg","doi":"10.1016/j.jhin.2025.06.012","DOIUrl":"https://doi.org/10.1016/j.jhin.2025.06.012","url":null,"abstract":"<p><strong>Background: </strong>Nosocomial infections in healthcare pose potentially life-threatening risks to patients and can drive up healthcare costs. To address this, the Dutch Collaborative Partnership for Infection Prevention Guidelines (SRI) creates evidence-based guidelines to reduce infections in hospitals, long-term care facilities, and public health settings (1). We evaluated professionals' experiences with the evidence-based guideline development process to gain insights into the feasibility of the current process.</p><p><strong>Methods: </strong>Guideline development group (GDG) members from 2021-2022 were surveyed. Data on expectations prior to participation; experienced workload; satisfaction with the composition of the GDG, the guideline development process, and generic or domain-specific guidelines; and implementation factors, were collected and analyzed.</p><p><strong>Results: </strong>Eighty of 168 (48%) members of 17 GDGs responded. Expectations were clear to 46 (57%) respondents prior to participating. Twenty-seven (34%) respondents found time investment higher than expected, especially literature screening. Seventy (88%) respondents agreed their association was represented sufficiently, and 69 (86%) reported there was sufficient knowledge on infection prevention. However, 25 (31%) respondents expressed that Grading of Recommendations Assessment, Development and Evaluation (GRADE) is unsuitable to assess available evidence, although not offering alternatives. Thirty-two (40%) respondents wish for the adaptation of generic guidelines into domain-specific guidelines.</p><p><strong>Conclusions: </strong>Respondents emphasized the need for adaptation of generic guidelines into domain-specific guidelines, implying the necessity to develop guidelines that closely align with the needs of the field. Addressing areas for improvement, such as workload management, methodological concerns, and implementation strategies, are crucial to optimize the development process and ensure the guidelines' impact on infection prevention.</p>","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumatic tube transport system carriers made from urethane contaminated with environmental pathogens","authors":"O. Imataki ,&nbsp;R. Masumoto ,&nbsp;M. Hamano ,&nbsp;M. Ishimatsu ,&nbsp;M. Tamura ,&nbsp;A. Kitanaka","doi":"10.1016/j.jhin.2025.03.006","DOIUrl":"10.1016/j.jhin.2025.03.006","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"161 ","pages":"Pages 161-163"},"PeriodicalIF":3.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why is the pathogen positivity rate so high even after chlorhexidine–alcohol disinfection?","authors":"Y. Xiao ,&nbsp;C. Tan ,&nbsp;J. Zou ,&nbsp;S. Chen ,&nbsp;B. Tian ,&nbsp;A. Wu ,&nbsp;C. Li","doi":"10.1016/j.jhin.2025.01.018","DOIUrl":"10.1016/j.jhin.2025.01.018","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"161 ","pages":"Pages 166-167"},"PeriodicalIF":3.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Bacterial reservoir in deeper skin is a potential source for surgical site and biomaterial-associated infections’; reply to Xiao et al.","authors":"C. Guarch-Pérez ,&nbsp;M. Riool ,&nbsp;L. de Boer ,&nbsp;P. Kloen ,&nbsp;S.A.J. Zaat","doi":"10.1016/j.jhin.2025.03.013","DOIUrl":"10.1016/j.jhin.2025.03.013","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"161 ","pages":"Pages 168-169"},"PeriodicalIF":3.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Borderline oxacillin-resistant Staphylococcus aureus: an emerging threat in the hospital environment","authors":"G. Hughes ,&nbsp;S. Wilkinson ,&nbsp;J. Harker ,&nbsp;I. Gupta ,&nbsp;E. Holden ,&nbsp;M. Garvey","doi":"10.1016/j.jhin.2024.09.029","DOIUrl":"10.1016/j.jhin.2024.09.029","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"161 ","pages":"Pages 159-160"},"PeriodicalIF":3.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing healthcare workforce management: the economic impact of in-house molecular testing during the COVID-19 pandemic","authors":"P.T. Coutinho ,&nbsp;É.J. Manchesski ,&nbsp;P.D. Batista ,&nbsp;V.U. Palma ,&nbsp;J.P.F. Fortti ,&nbsp;G.M. Faleiro ,&nbsp;L. da S. Almeida ,&nbsp;M. Reche ,&nbsp;A.C. Pasqualotto","doi":"10.1016/j.jhin.2025.04.001","DOIUrl":"10.1016/j.jhin.2025.04.001","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"161 ","pages":"Pages 164-165"},"PeriodicalIF":3.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The hidden burden of VRE screening tests in patients colonized with VRE in an acute setting: a retrospective analysis","authors":"S.P. Mathew ,&nbsp;L. Reynolds ,&nbsp;S. Nally ,&nbsp;S. Frost ,&nbsp;V. Boland","doi":"10.1016/j.jhin.2025.04.002","DOIUrl":"10.1016/j.jhin.2025.04.002","url":null,"abstract":"","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"161 ","pages":"Pages 170-171"},"PeriodicalIF":3.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of cleaning effects of vacuum-assisted boiling washer-disinfectors on rigid endoscopic instruments: impact of cleaning cycle parameters.","authors":"Huan-Huan Tong, Rui Zhu, Jing-Jing Ding, Ying-Yu Hu, Dan-Qiao Yin, Yu Zhang, Shao-Hua Hu","doi":"10.1016/j.jhin.2025.06.013","DOIUrl":"https://doi.org/10.1016/j.jhin.2025.06.013","url":null,"abstract":"<p><strong>Background: </strong>Vacuum-assisted boiling washer-disinfectors are widely favoured for cleaning rigid endoscopic instruments, but the standard cleaning cycle is time-consuming, which affects the turnover of instruments.</p><p><strong>Aim: </strong>To compare the cleaning effects of different cleaning cycle parameters on rigid endoscopic instruments and determine parameter settings that balanced effectiveness and efficiency.</p><p><strong>Methods: </strong>600 rigid endoscopic instruments that had been used in laparoscopic cholecystectomies were randomly divided into four groups, including one control group (standard parameters) and three experimental groups which differed in enzymatic washing time, temperature, or detergent concentration. The cleaning quality was assessed via visual inspection with a 5x magnifier and borescope, adenosine triphosphate (ATP) bioluminescence assay, and residual protein detection.</p><p><strong>Findings: </strong>No significant difference was found in the cleaning qualification rate among the four groups using a visual inspection with either the 5x magnifier or the borescope (all P > 0.05). However, significant differences were observed in the ATP bioluminescence assay and residual protein detection (all P < 0.05). Pairwise comparisons revealed group A had higher qualification rates than groups C or D (P < 0.0167). Significant differences in relative light unit (RLU) values were observed between groups in the ATP bioluminescence assay (P < 0.05): group A showed lower RLU values than groups B and C, and group D showed lower RLU values than group C (all P < 0.001).</p><p><strong>Conclusion: </strong>Increasing the enzymatic washing temperature of the vacuum-assisted boiling washer-disinfector to compensate for the flushing and rinsing steps shortened the cleaning time and improved the reprocessing efficiency of rigid endoscopic instruments while maintaining high cleaning quality.</p>","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}