Journal of Pediatrics最新文献

{"title":"The Multidimensional Condition of Systemic Cooling Poverty Affecting Children's Health Worldwide.","authors":"Massimo Pettoello-Mantovani, Pietro Ferrara, Maria Pastore, Donjeta Bali, Tudor Lucian Pop, Ida Giardino, Mehmet Vural","doi":"10.1016/j.jpeds.2024.114337","DOIUrl":"10.1016/j.jpeds.2024.114337","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114337"},"PeriodicalIF":3.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Infant Botulism - Correction to \"Cognitive Bias in an Infant with Constipation\".","authors":"Haydee A Dabritz, Connie H Chung, Jennifer S Read, Jessica M Khouri","doi":"10.1016/j.jpeds.2024.114332","DOIUrl":"10.1016/j.jpeds.2024.114332","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114332"},"PeriodicalIF":3.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Esophageal Atresia with Tracheoesophageal Fistula Is Associated with Consanguinity in the Bedouins of the Negev.","authors":"Joël Zlotogora","doi":"10.1016/j.jpeds.2024.114333","DOIUrl":"10.1016/j.jpeds.2024.114333","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114333"},"PeriodicalIF":3.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with Pediatric Drowning-Associated Lung Injury.","authors":"Rohit P Shenoi, James E Crowe, Scott R Dorfman, Kelly R Bergmann, Rakesh D Mistry, Selena Hariharan, Melissa M Tavarez, Shannon Wai, Jennifer L Jones, Melissa L Langhan, Caleb E Ward, Tracy E McCallin, Usha Sethuraman, Nipam Shah, Donna Mendez, Katherine H Wolpert, Claritsa Santos-Malave, Timothy Ruttan, Kimberly S Quayle, Pamela Okada, Beth Bubolz, James F Buscher, Ryan McKee, Karen Mangold, Wendi-Jo Wendt, Amy D Thompson, Jeffrey Hom, Anne F Brayer, Mercedes M Blackstone, Courtney Brennan, W Scott Russell, Maneesha Agarwal, Kajal Khanna, Jeff Louie, David Sheridan, Elizabeth A Camp","doi":"10.1016/j.jpeds.2024.114459","DOIUrl":"10.1016/j.jpeds.2024.114459","url":null,"abstract":"<p><strong>Objective: </strong>To identify risk factors for clinically-important drowning-associated lung injury (ciDALI) in children.</p><p><strong>Study design: </strong>This was a cross-sectional study of children (0 through 18 years) who presented to 32 pediatric emergency departments (EDs) from 2010 through 2017. We reviewed demographics, comorbidities, prehospital data, chest radiographs reports, and ED course from emergency medical services, medical, and fatality records. We defined ciDALI as presence of any of the following: (1) drowning deaths without cerebral/cervical spine injuries; (2) supplemental oxygen >8 hours postdrowning; (3) invasive/noninvasive ventilatory support in first 24 hours; or (4) abnormal chest radiographic findings in the first 24 hours without resolution within 8 hours postdrowning. We used mixed-methods logistic regression with site as random effect to identify risk factors and bootstrapping to reduce overfitting.</p><p><strong>Results: </strong>We enrolled 4213 patients (no ciDALI = 3045 [72%]; ciDALI = 1168 [28%]). The median age was 3 years (IQR: 1, 5). The risk factors for patients with ciDALI were age >5 years old (aOR: 2.4 [95% CI: 2.0-3.0]); submersion >5 minutes (aOR: 6.0 [95% CI: 3.5-10.2]); any scene resuscitation (aOR: 3.3 [95% CI: 2.5-4.5]) and at presentation to the ED abnormal mentation (aOR: 6.4 [95% CI: 4.1-10.0]), abnormal heart rate (aOR: 1.8 [95% CI: 1.6-2.1]), abnormal respiratory rate (aOR: 1.8 [95% CI: 1.4-2.3]), hypotension (aOR: 2.8 [95% CI: 1.0-7.4]), and abnormal lung auscultation (OR: 3.9 [95% CI: 2.9-5.4]).</p><p><strong>Conclusions: </strong>Pediatric ciDALI risk factors include older age, scene resuscitation, prolonged submersion, and abnormal pulmonary, hemodynamic, and neurological findings at ED presentation. Prospective research to stratify risks based on submersion-related lung injury is needed to help determine short-term outcome and optimize patient disposition.</p>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114459"},"PeriodicalIF":3.9,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and Patterns in United States Pediatric Care Coordination, 2016-2022.","authors":"Myriam Casseus, Nancy E Reichman","doi":"10.1016/j.jpeds.2024.114457","DOIUrl":"10.1016/j.jpeds.2024.114457","url":null,"abstract":"<p><p>Pediatric care coordination (PCC) has been shown to improve quality of care and health outcomes. This study documents trends and patterns in parent-reported receipt of PCC between 2016 and 2022 (n = 279 546). Rates of PCC declined throughout this period and were particularly low for children with special health care needs.</p>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114457"},"PeriodicalIF":3.9,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing Incidence of Serious Head and Neck Infections among Children in the United States, 2018-2023.","authors":"Serena Yun-Chen Tsai, Stephanie Hadley, Amanda S Growdon, Kevin Sheng-Kai Ma, Jonathan M Mansbach","doi":"10.1016/j.jpeds.2024.114458","DOIUrl":"10.1016/j.jpeds.2024.114458","url":null,"abstract":"<p><p>There has been a significant, postpandemic increase in the incidence of serious head and neck infections among children aged <18 years since 2021, compared with the stable incidence of nontransmissible osteomyelitis and serious head and neck infections in adults from 2018 to 2023. The etiology of this increase requires further study.</p>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114458"},"PeriodicalIF":3.9,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Patent Ductus Arteriosus Management and Outcomes in Infants Born at 26-28 Weeks' Gestation.","authors":"Dinushan C Kaluarachchi, Matthew A Rysavy, Barbara T Do, Valerie Y Chock, Matthew M Laughon, Carl H Backes, Tarah T Colaizy, Edward F Bell, Patrick J McNamara","doi":"10.1016/j.jpeds.2024.114456","DOIUrl":"10.1016/j.jpeds.2024.114456","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between the secular decrease in treatment of patent ductus arteriosus (PDA) and trends in neonatal mortality and morbidity in infants born at 26 0/7-28 6/7 weeks' gestation.</p><p><strong>Study design: </strong>A retrospective cohort study including infants born between 2012 and 2021 in continually participating hospitals in the National Institute of Child Health and Human Development Neonatal Research Network. The primary composite outcome was defined as surgical necrotizing enterocolitis, grade 2-3 bronchopulmonary dysplasia (BPD), severe intraventricular hemorrhage, or death. Relationships of temporal trends in PDA treatment with the primary composite outcome and its components were analyzed using a multilevel model accounting for patient-level factors. A separate analysis assessed these relationships stratified by hospital changes in PDA treatment.</p><p><strong>Results: </strong>The study included 7864 infants. There was a decrease in any PDA treatment from 21% to 16% (P < .01) and an increase in the primary composite outcome from 24% to 36% (P < .01). Change in the primary outcome was driven by increased grade 2-3 BPD (13%-26%, P < .01), with grade 2 BPD accounting for most of this increase (10%-22%, P < .01). Temporal decreases in PDA treatment were associated with increases in the primary outcome and grade 2-3 BPD after adjusting for patient-level factors (P < .01). However, stratified analyses showed that grade 2-3 BPD increased in all hospital groups, regardless of changes in PDA management.</p><p><strong>Conclusions: </strong>From 2012 to 2021, temporal decreases in PDA treatment for infants 26-28 weeks were associated with an increase in grade 2-3 BPD. However, caution is warranted in determining causality. Reasons for increased grade 2-3 BPD during the past decade warrant investigation.</p><p><strong>Trial registration: </strong>Generic Database: NCT00063063.</p>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114456"},"PeriodicalIF":3.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating Resistance and Adaptation in Health Care: How Pediatricians Can Balance Transformation and Children's Needs.","authors":"Massimo Pettoello-Mantovani, Donjeta Bali, Ida Giardino, Mehmet Vural, Flavia Indrio, Giuseppe Buonocore, Maria Pastore","doi":"10.1016/j.jpeds.2024.114446","DOIUrl":"10.1016/j.jpeds.2024.114446","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114446"},"PeriodicalIF":3.9,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Milking of the Cut Cord During Stabilization of Infants Born Very Premature: A Randomized Controlled Trial.","authors":"Walid El-Naggar, Souvik Mitra, Jayani Abeysekera, Tim Disher, Christy Woolcott, Tara Hatfield, Douglas McMillan, Jon Dorling","doi":"10.1016/j.jpeds.2024.114444","DOIUrl":"10.1016/j.jpeds.2024.114444","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the feasibility of cut-umbilical cord milking (C-UCM) during stabilization of preterm infants after birth.</p><p><strong>Study design: </strong>This was a pilot randomized controlled trial of initial resuscitation. Infants born to eligible, consenting women presenting in preterm labor at <32 weeks' gestation were randomized to receive either the standard practice of deferred cord clamping (DCC) for 30-60 seconds at birth or C-UCM while supporting breathing and following 30 seconds of DCC. The primary outcome was feasibility in terms of percentage recruitment, intervention compliance, safety, and study completion. Short-term clinical outcomes were collected. Analysis was by intention to treat.</p><p><strong>Results: </strong>Of the 133 pregnant women approached, 93 consented to participate (70%). Fifty infants delivered <32 weeks' gestation were randomized to either C-UCM (25) or DCC (25). Baseline characteristics of infants were similar. All participants completed the study. One infant in the C-UCM group and 5 infants in the DCC group did not receive the allocated intervention. Median (IQR) time to cord milking was 62 (54, 99) seconds and median (IQR) length of the cut-cord milked was 20 (14, 29) cm. C-UCM was not associated with increased adverse effects compared with DCC.</p><p><strong>Conclusion: </strong>Milking of the long-cut cord after 30 seconds of DCC while supporting breathing was feasible and not associated with significant adverse effects. A larger randomized controlled trial is required to assess the efficacy and safety of this approach on clinical outcomes. C-UCM may be especially useful in situations when DCC is not feasible.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov: NCT03852134.</p>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114444"},"PeriodicalIF":3.9,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual-, Hospital-, and Community-Level Factors Associated with Sudden Unexpected Infant Death Among Infants Born Preterm in 5 US States.","authors":"Sunah S Hwang, Stephanie L Bourque, Kathleen E Hannan, Molly Passarella, Joshua Radack, Brielle Formanowski, Scott A Lorch","doi":"10.1016/j.jpeds.2024.114445","DOIUrl":"10.1016/j.jpeds.2024.114445","url":null,"abstract":"<p><strong>Objective: </strong>To investigate individual-, hospital-, and community-level factors associated with sudden unexpected infant death (SUID) among infants born preterm.</p><p><strong>Study design: </strong>The following linked dataset from 5 states (California, Michigan, Oregon, Pennsylvania, and South Carolina) from 2005 through 2020 was used: (1) infant birth and death certificates; (2) maternal and infant birth hospitalization discharge records; (3) birthing hospital data from the American Hospital Association; and (4) community-level data from the Social Vulnerability Index (SVI).) Multivariable models were used to assess the independent association between these multilevel factors and SUID, adjusting for several maternal and infant characteristics.</p><p><strong>Results: </strong>Overall, we found that maternal demographic factors (race and ethnicity, education, insurance) and infant gestational age were significant predictors of SUID. There was no difference in SUID odds by state, urban influence code, and maternal complications of pregnancy. Compared with mothers who lived in areas with the lowest SVI, those who resided in the highest SVI were more likely to experience SUID. There was no difference in SUID odds between infants who did or did not experience one or more complications of prematurity. For hospital-level factors, there was no difference in SUID odds among infants cared for in teaching vs nonteaching hospitals or in low vs high volume preterm birth hospitals.</p><p><strong>Conclusion: </strong>Individual- and community-level factors were associated with SUID among infants born preterm. The neonatal intensive care unit hospitalization may provide a critical window of opportunity to engage families about SUID-risk reducing practices.</p>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":" ","pages":"114445"},"PeriodicalIF":3.9,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}