Karola de Graaf MD , Yael E.P. Kwakman BSc , Ineke de Kruijff MD, PhD , Ellen Tromp PhD , Ingrid I.E. Staal PhD , Leslie E. Katch PhD , Tiffany Burkhardt PhD , Marc A. Benninga MD, PhD , Tessa J. Roseboom PhD , Arine M. Vlieger MD, PhD
{"title":"Validation of the Dutch Infant Crying and Parent Well-Being Screening Tool in Parents of Infants Less than 12 Months of Age","authors":"Karola de Graaf MD , Yael E.P. Kwakman BSc , Ineke de Kruijff MD, PhD , Ellen Tromp PhD , Ingrid I.E. Staal PhD , Leslie E. Katch PhD , Tiffany Burkhardt PhD , Marc A. Benninga MD, PhD , Tessa J. Roseboom PhD , Arine M. Vlieger MD, PhD","doi":"10.1016/j.jpeds.2024.114326","DOIUrl":"10.1016/j.jpeds.2024.114326","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate reliability and validity of the Dutch version of the Infant Crying and Parent Well-Being (ICPW) tool in identifying parents struggling with infant crying in the first year of life.</div></div><div><h3>Study design</h3><div>The original ICPW tool was translated into Dutch following established guidelines. The internal consistency and criterion validity of the Dutch ICPW tool were evaluated using a cross-sectional design. The translated ICPW tool and validated questionnaires on parental depression, stress, anxiety, and parenting balance were presented to parents of infants under 12 months during child health care visits and online.</div></div><div><h3>Results</h3><div>The survey was completed by 488 parents, 400 mothers and 88 fathers. Of these, 172 participated after a child health care visit and 316 via online platforms. The Dutch ICPW showed satisfactory internal consistency (α = 0.69) and excellent criterion validity with parental mental health measures (r = 0.53-0.85). ICPW scores demonstrated positive correlations with parental depression, stress, and anxiety levels, and a negative correlation with parenting balance. Both mothers and fathers with a positive ICPW screen (≥3) reported significantly higher levels of parental mental health issues compared with those with a negative screen (<em>P</em> < .001). The ICPW was positive in 32% of the parents (n = 155), with consistent total scores regardless of the infant's increasing age (r = −0.024, <em>P</em> = .59). The ICPW tool exhibited a strong negative predictive value (93%) for diagnosing postpartum depression.</div></div><div><h3>Conclusions</h3><div>The Dutch ICPW tool is a reliable and valid screening instrument for identifying parents struggling with infant crying.</div></div>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"276 ","pages":"Article 114326"},"PeriodicalIF":3.9,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lindsay M. Thomson MD , Sierra Niemiec MS , Christopher A. Mancuso PhD , Ludmila Khailova MS , Eiman Ali MBBS , Aneesa Syed BS, MBA , Kelly R. Wolfe PhD , Jack Zakrzewski MD , Matthew Stone MD, PhD , Robert Hyslop RN , Benjamin S. Frank MD , Jesse A. Davidson MD, MPH, MSc
{"title":"Disruption of the Circulating Proteome in Neonates Receiving Extracorporeal Membrane Oxygenation Following Congenital Heart Disease Surgery: A Nested Case-Control Study","authors":"Lindsay M. Thomson MD , Sierra Niemiec MS , Christopher A. Mancuso PhD , Ludmila Khailova MS , Eiman Ali MBBS , Aneesa Syed BS, MBA , Kelly R. Wolfe PhD , Jack Zakrzewski MD , Matthew Stone MD, PhD , Robert Hyslop RN , Benjamin S. Frank MD , Jesse A. Davidson MD, MPH, MSc","doi":"10.1016/j.jpeds.2024.114322","DOIUrl":"10.1016/j.jpeds.2024.114322","url":null,"abstract":"<div><div>This nested case-control study identified broad dysregulation of the circulating proteome in neonates receiving postoperative extracorporeal membrane oxygenation support after congenital heart disease surgery, including differential responses in those not surviving to hospital discharge. Tissue hypoxia and mitochondrial-associated proteins may represent novel candidate biomarkers for poor extracorporeal membrane oxygenation outcomes.</div></div>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"276 ","pages":"Article 114322"},"PeriodicalIF":3.9,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leena Nahata MD , Shylaja Srinivasan MD, MAS , Charleen I. Roche BA , Karla F. Leavens MD, PhD , Mimi S. Kim MD, MSc , Amy Levenson MD , Lisa Swartz Topor MD, MMSc , Kanakadurga Singer MA, MD , Shana McCormack MD, MTR
{"title":"Measuring Up: Do Pediatric Endocrinology Fellows’ Career Expectations Align with Workforce Reality?","authors":"Leena Nahata MD , Shylaja Srinivasan MD, MAS , Charleen I. Roche BA , Karla F. Leavens MD, PhD , Mimi S. Kim MD, MSc , Amy Levenson MD , Lisa Swartz Topor MD, MMSc , Kanakadurga Singer MA, MD , Shana McCormack MD, MTR","doi":"10.1016/j.jpeds.2024.114321","DOIUrl":"10.1016/j.jpeds.2024.114321","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"275 ","pages":"Article 114321"},"PeriodicalIF":3.9,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adetokunbo Akinseye MBBS , Christy Pylypjuk MD, MSc , Diane Moddemann MD, MEd , Jehier Afifi MBBCh, MSc , Rudaina Banihani MD, MHPE , Khalid Aziz MBBS, MEd (IT) , Dianna Wang MD , Mary Seshia MBChB
{"title":"Maternal Diabetes and Neurodevelopmental Outcomes of Infants Born Before 29 Weeks’ Gestation","authors":"Adetokunbo Akinseye MBBS , Christy Pylypjuk MD, MSc , Diane Moddemann MD, MEd , Jehier Afifi MBBCh, MSc , Rudaina Banihani MD, MHPE , Khalid Aziz MBBS, MEd (IT) , Dianna Wang MD , Mary Seshia MBChB","doi":"10.1016/j.jpeds.2024.114319","DOIUrl":"10.1016/j.jpeds.2024.114319","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the neurodevelopmental outcomes of infants born at <29 weeks’ gestation and exposed to diabetes in pregnancy with those unexposed.</div></div><div><h3>Study design</h3><div>This was a retrospective cohort study using the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network databases. Infants born <29 weeks’ gestation and admitted to a level 3 neonatal intensive care unit from 2009 through 2018 who had neurodevelopmental assessments at 18-24 months corrected age were eligible. The 2 primary outcomes were as follows: (1) Neurodevelopmental impairment (NDI) (≥1 of Bayley-III scores < 85 in any domain, cerebral palsy, or vision or hearing impairment); and (2) significant NDI (sNDI) (≥1 of Bayley-III scores < 70 in any domain, cerebral palsy Gross Motor Function Classification System ≥ 3, bilateral blindness, or need for hearing aids or cochlear implants). Secondary outcomes were the individual components of NDI and sNDI. Adjusted odds ratios with 95% CIs were calculated to determine outcomes between groups.</div></div><div><h3>Results</h3><div>Of 13 988 eligible infants, 55% attended neurodevelopmental follow-up assessments. Infants exposed to diabetes had increased odds of NDI compared with those unexposed (aOR 1.09 (95% CI 1.08-1.54); there was no difference in sNDI (aOR 1.07 (95% CI 0.84-1.36). Language and motor delays were more common in those exposed to maternal diabetes.</div></div><div><h3>Conclusions</h3><div>Higher rates of NDI, language, or motor delays were present in infants born at <29 weeks' gestation exposed to diabetes in utero. Future research is needed to determine the etiology and clinical significance of these findings.</div></div>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"276 ","pages":"Article 114319"},"PeriodicalIF":3.9,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ciaran S. Phibbs PhD , Molly Passarella MS , Susan K. Schmitt RN, PhD , Ashley Martin MPH , Scott A. Lorch MD, MSCE
{"title":"The Impact of Hospital Delivery Volumes of Newborns Born Very Preterm on Mortality and Morbidity","authors":"Ciaran S. Phibbs PhD , Molly Passarella MS , Susan K. Schmitt RN, PhD , Ashley Martin MPH , Scott A. Lorch MD, MSCE","doi":"10.1016/j.jpeds.2024.114323","DOIUrl":"10.1016/j.jpeds.2024.114323","url":null,"abstract":"<div><h3>Objective</h3><div>To examine if the annual patient volume of infants born very preterm (VPT, gestational age <32 weeks) at a hospital is associated with neonatal mortality and morbidity.</div></div><div><h3>Study design</h3><div>We performed an observational, secondary data analysis using a 20-year panel of birth certificates linked to hospital discharge abstracts, including transfers in California, Michigan, Missouri, Oregon, Pennsylvania, and South Carolina from 1996 through 2015. The study included all in-hospital VPT deliveries (n = 208 261). Study outcomes were in-hospital mortality or serious morbidity (intraventricular hemorrhage, necrotizing enterocolitis, retinopathy of prematurity, or bronchopulmonary dysplasia), attributed to the hospital of birth. Poisson regression models estimated the risk-adjusted relative risk (RR) for mortality and serious morbidity across different patient volume categories within a given hospital using hospital fixed effects.</div></div><div><h3>Results</h3><div>The risk of mortality and serious morbidity for VPT infants increased as the number of infants born VPT at a hospital decreased. Compared with VPT delivery volumes >100 infants per year, the risk of mortality increased when a given hospital had VPT delivery volumes < 60 per year, ranging from a RR of 1.13 (95% C.I. 1.02-1.25) for volumes between 50 to 59 and 1.39 (1.19-1.62) for VPT volumes <10, and the risk of mortality or serious morbidity increased when a given hospital had VPT volumes <100, ranging from a RR of 1.05 (1.02-1.08) for volumes between 90 to 99 and 1.27 (1.19-1.36) for VPT volumes <10.</div></div><div><h3>Conclusions</h3><div>These results suggest that, for VPT infants, the risk of both mortality and mortality or serious morbidity is increased as the VPT volume within a given hospital declines.</div></div>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"276 ","pages":"Article 114323"},"PeriodicalIF":3.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David R. Jacobs Jr. PhD, Jessica G. Woo PhD, Stephen R. Daniels MD, PhD
{"title":"Early Screening for Obesity: An Opportunity for Pediatrics","authors":"David R. Jacobs Jr. PhD, Jessica G. Woo PhD, Stephen R. Daniels MD, PhD","doi":"10.1016/j.jpeds.2024.114320","DOIUrl":"10.1016/j.jpeds.2024.114320","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"275 ","pages":"Article 114320"},"PeriodicalIF":3.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S0022-3476(24)00364-0","DOIUrl":"10.1016/S0022-3476(24)00364-0","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"273 ","pages":"Article 114261"},"PeriodicalIF":3.9,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142240000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RSV Prevention in Infants is Feasible and Remarkably Effective","authors":"Sarah S. Long MD","doi":"10.1016/j.jpeds.2024.114281","DOIUrl":"10.1016/j.jpeds.2024.114281","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"273 ","pages":"Article 114281"},"PeriodicalIF":3.9,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142238727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editors’ Perspectives – October 2024","authors":"Stephen R. Daniels MD, PhD","doi":"10.1016/j.jpeds.2024.114282","DOIUrl":"10.1016/j.jpeds.2024.114282","url":null,"abstract":"","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"273 ","pages":"Article 114282"},"PeriodicalIF":3.9,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142238728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}