{"title":"Commentary on: \"effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial\".","authors":"Anjali Raghuwanshi, Saliha Rafat, Adarsh Kumar Srivastav","doi":"10.2340/jrm.v56.41133","DOIUrl":"10.2340/jrm.v56.41133","url":null,"abstract":"","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm41133"},"PeriodicalIF":2.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inge E Eriks-Hoogland, Lorena Müller, Benjamin D N Hirsch, Lea Studer, Armin Gemperli, Collene E Anderson
{"title":"Non-adherence to follow-up care in persons with spinal cord injury within 10 years after initial rehabilitation.","authors":"Inge E Eriks-Hoogland, Lorena Müller, Benjamin D N Hirsch, Lea Studer, Armin Gemperli, Collene E Anderson","doi":"10.2340/jrm.v56.41083","DOIUrl":"10.2340/jrm.v56.41083","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to describe the temporal dynamics of and risk factors for non-adherence to outpatient follow-up care in the first 10 years after spinal cord injury.</p><p><strong>Design: </strong>Retrospective single-centre cohort study using data from medical records and municipal resident registers.</p><p><strong>Subjects/patients: </strong>Patients admitted to a specialized spinal cord injury centre in Switzerland discharged between 1 January 2010 and 31 December 2012 (n = 225). Time-to-event analysis was used to investigate the timing of the first non-adherence event, its association with spinal cord injury, and sociodemographic characteristics.</p><p><strong>Results: </strong>36% of patients were adherent to annual follow-up appointments; 2% formally transferred to another SCI centre; 44% were non-adherent for general reasons (patient's will to discontinue care [12%] or unknown reasons [32%]); and 18% were non-adherent due to death. Risk factors for non-adherence included older age, lack of long-term partner, and more than 2 h of travel time to the clinic. In the youngest age group (18-30 years), 55% were non-adherent after 10 years.</p><p><strong>Conclusion: </strong>A relevant proportion of individuals with spinal cord injury were lost to annual follow-up care. A holistic approach to patient engagement integrating solutions such as telemedicine and involvement of support networks could reduce the risk of non-adherence.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm41083"},"PeriodicalIF":2.5,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of ultrasound- vs. landmark-guided injections for musculoskeletal pain: an umbrella review.","authors":"Peng-Chieh Shen, Ting-Yu Lin, Wei-Ting Wu, Levent Özçakar, Ke-Vin Chang","doi":"10.2340/jrm.v56.40769","DOIUrl":"10.2340/jrm.v56.40769","url":null,"abstract":"<p><strong>Objective: </strong>This umbrella review synthesizes systematic reviews and meta-analyses to reach a conclusion concerning the overall effectiveness of ultrasound-guided vs landmark-guided injections for treating musculoskeletal pain.</p><p><strong>Design: </strong>Umbrella review.</p><p><strong>Methods: </strong>PubMed, EMBASE, MEDLINE, and Web of Science were searched for relevant systematic reviews and meta-analyses from inception to March 2024. Critical appraisal, data extraction, and synthesis were performed in accordance with the criteria for conducting an umbrella review.</p><p><strong>Results: </strong>Seventeen articles, comprising 4 systematic reviews and 13 meta-analyses, were included. Using the AMSTAR2 instrument for quality assessment, 3 articles were rated as high quality, 1 as moderate, 7 as low, and 6 as critically low. Generally, ultrasound-guided injections were found to be more accurate than landmark-guided injections, particularly in the shoulder joint, though the results for pain relief and functional outcomes varied. Ultrasound guidance was notably effective for injections into the bicipital groove, wrist, hip, and knee - yielding greater accuracy and improved pain management. Both ultrasound-guided and landmark-guided techniques showed low incidence of adverse effects.</p><p><strong>Conclusion: </strong>This umbrella review offers an in-depth analysis of the comparative effectiveness of ultrasound-guided and landmark-guided injections across a range of musculoskeletal sites/conditions. The findings suggest that ultrasound-guided is a reliable method.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm40679"},"PeriodicalIF":2.5,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mirko Filippetti, Linde Lugoboni, Rita Di Censo, Luca Degli Esposti, Salvatore Facciorusso, Valentina Varalta, Andrea Santamato, Massimiliano Calabrese, Nicola Smania, Alessandro Picelli
{"title":"Classification of upper limb spasticity patterns in patients with multiple sclerosis: a pilot observational study.","authors":"Mirko Filippetti, Linde Lugoboni, Rita Di Censo, Luca Degli Esposti, Salvatore Facciorusso, Valentina Varalta, Andrea Santamato, Massimiliano Calabrese, Nicola Smania, Alessandro Picelli","doi":"10.2340/jrm.v56.40548","DOIUrl":"10.2340/jrm.v56.40548","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to provide a classification of the upper limb patterns in patients with upper limb spasticity due to multiple sclerosis.</p><p><strong>Design: </strong>Pilot observational study.</p><p><strong>Patients: </strong>Twenty-five adult patients with multiple sclerosis suffering from upper limb spasticity who underwent one segmental (i.e., proximal and distal upper limb) botulinum toxin treatment cycle were recruited.</p><p><strong>Methods: </strong>Patients remained in a sitting position during the evaluation. Upper limb spasticity postures (i.e., postural attitude of a single joint/anatomical region) were evaluated and recorded for the shoulder (adducted/internally rotated), elbow (flexed/extended), forearm (pronated/supinated/neutral), wrist (flexed/extended/neutral) and hand (fingers flexed/thumb in palm).</p><p><strong>Results: </strong>On the basis of the clinical observations, 6 patterns (i.e., sets of limb postures) of upper limb spasticity have been described according to the postures of the shoulder, elbow, forearm, and wrist.</p><p><strong>Conclusion: </strong>The patterns of upper limb spasticity in patients with multiple sclerosis described by this pilot study do not completely overlap with those observed in patients with post-stroke spasticity. This further supports the need to consider the features of spasticity related to its aetiology in order to manage patients appropriately.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm40548"},"PeriodicalIF":2.5,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Rimaud, Rodolphe Testa, Guillaume Y Millet, Paul Calmels
{"title":"Effects of carbon versus plastic ankle foot orthoses on gait outcomes and energy cost in patients with chronic stroke.","authors":"Diana Rimaud, Rodolphe Testa, Guillaume Y Millet, Paul Calmels","doi":"10.2340/jrm.v56.35213","DOIUrl":"10.2340/jrm.v56.35213","url":null,"abstract":"<p><strong>Objective: </strong>To compare the walking performances of hemiplegic subjects with chronic stroke under 3 conditions: with a new standard carbon fibre ankle foot orthosis (C-AFO), with a personal custom-made plastic AFO (P-AFO), and without any orthosis (No-AFO).</p><p><strong>Design: </strong>Randomized, controlled crossover design.</p><p><strong>Patients: </strong>Fifteen chronic patients with stroke (3 women and 12 men, 59 [10] years, 13 [15] years since injury).</p><p><strong>Methods: </strong>Patients performed 3 randomized sessions (with C-AFO, P-AFO, no-AFO), consisting of a 6-min walk test (6MWT) with VO2 measurement and a clinical gait analysis. Energy cost (Cw), walking speed, spatio-temporal, kinetic, and kinematic variables were measured.</p><p><strong>Results: </strong>No significant differences were found between the C-AFO and P-AFO conditions. Distance and walking speed in the 6MWT increased by 12% and 10% (p < 0.001) and stride width decreased by -8.7% and -13% (p < 0.0001) with P-AFO and C-AFO compared with the No-AFO condition. Cw decreased by 15% (p < 0.002), stride length increased by 10% (p < 0.01), step length on affected leg increased by 8% (p < 0.01), step length on contralateral leg by 13% (p < 0.01), and swing time on the contralateral leg increased by 6% (p < 0.01) with both AFO compared with the No-AFO condition.</p><p><strong>Conclusion: </strong>The use of an off-the-shelf composite AFO (after a short habituation period) in patients with chronic stroke immediately improved energy cost and gait outcomes to the same extent as their usual custom-made AFO.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm35213"},"PeriodicalIF":2.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognitive load in individuals with a transfemoral amputation during single- and dual-task walking: a pilot study of brain activity in people using a socket prosthesis or a bone-anchored prosthesis.","authors":"Saffran Möller, Kerstin Hagberg, Nerrolyn Ramstrand","doi":"10.2340/jrm.v56.40111","DOIUrl":"10.2340/jrm.v56.40111","url":null,"abstract":"<p><strong>Objective: </strong>To explore cognitive load in people with transfemoral amputations fitted with socket or bone-anchored prostheses by describing activity in the left and right dorsolateral prefrontal cortices during single- and dual-task walking.</p><p><strong>Design: </strong>Cross-sectional pilot study.</p><p><strong>Patients: </strong>8 socket prosthesis users and 8 bone-anchored prosthesis users. All were fitted with microprocessor-controlled prosthetic knees.</p><p><strong>Methods: </strong>Participants answered self-report questionnaires and performed gait tests during 1 single-task walking condition and 2 dual-task walking conditions. While walking, activity in the dorsolateral prefrontal cortex was measured using functional near-infrared spectroscopy. Cognitive load was investigated for each participant by exploring the relative concentration of oxygenated haemoglobin in the left and right dorsolateral prefrontal cortex. Symmetry of brain activity was investigated by calculating a laterality index.</p><p><strong>Results: </strong>Self-report measures and basic gait variables did not show differences between the groups. No obvious between-group differences were observed in the relative concentration of oxygenated haemoglobin for any walking condition. There was a tendency towards more right-side brain activity for participants using a socket prosthesis during dual-task conditions.</p><p><strong>Conclusions: </strong>This pilot study did not identify substantial differences in cognitive load or lateralization between socket prosthesis users and bone-anchored prosthesis users.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm40111"},"PeriodicalIF":2.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early comprehensive pulmonary rehabilitation for hospitalized patients with acute ex-acerbation of chronic obstructive pulmonary disease: a randomized controlled trial.","authors":"Yuqin Zeng, Qian Wu, Yan Chen, Shan Cai","doi":"10.2340/jrm.v56.39953","DOIUrl":"10.2340/jrm.v56.39953","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether an early comprehensive pulmonary rehabilitation intervention initiated during hospital admission is safe and effective for patients with acute exacerbation of chronic obstructive pulmonary disease.</p><p><strong>Design: </strong>Prospective randomized controlled study.</p><p><strong>Subjects/patients: </strong>Patients with acute exacerbation of chronic obstructive pulmonary disease.</p><p><strong>Methods: </strong>In total, 108 patients were randomized to the early comprehensive pulmonary rehabilitation and usual care groups within 48 hours. The 6-min walking distance, quality of life, breathlessness, and inspiratory muscle strength were measured on admission and discharge. Any adverse events of pulmonary rehabilitation were recorded.</p><p><strong>Results: </strong>On discharge, the patients in the early comprehensive pulmonary rehabilitation group had a more significant improvement in the 6-min walking distance (47.5 vs 23.0, p = 0.04). There was no significant difference in quality of life and breathlessness between the 2 groups. In the early comprehensive pulmonary rehabilitation group, inspiratory muscle strength and peak inspiratory flow were significantly improved, and the changes were much more pronounced than in the usual care group. There were no adverse events.</p><p><strong>Conclusion: </strong>Early comprehensive pulmonary rehabilitation is safe and effective for hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease, and should be performed during the early stage of hospitalization.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm39953"},"PeriodicalIF":2.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne Mette Berget, Vegard Pihl Moen, Merethe Hustoft, Jörg Assmus, Liv Inger Strand, Jan Sture Skouen, Øystein Hetlevik
{"title":"Use of primary healthcare services before and after specialized rehabilitation and its relation to changes in health and functioning: a longitudinal cohort study.","authors":"Anne Mette Berget, Vegard Pihl Moen, Merethe Hustoft, Jörg Assmus, Liv Inger Strand, Jan Sture Skouen, Øystein Hetlevik","doi":"10.2340/jrm.v56.39912","DOIUrl":"10.2340/jrm.v56.39912","url":null,"abstract":"<p><strong>Objective: </strong>To examine patients' use of primary healthcare (PHC) before and after specialized rehabilitation and its relation with self-reported health and functioning.</p><p><strong>Design: </strong>Longitudinal cohort study.</p><p><strong>Participants: </strong>451 rehabilitation patients.</p><p><strong>Methods: </strong>Register data were used to measure the frequency of visits to the general practitioner (GP) and physiotherapist (PT) in PHC 3 years before and after rehabilitation. Patients reported health (EQ-VAS) and functioning (SF-36) before rehabilitation and at 1 and 3 years after. Data are described for the total study cohort and subgroups with musculoskeletal disease (MSD) and cardiovascular disease (CVD).</p><p><strong>Results: </strong>There was an increase in GP and PT visits preceding rehabilitation and a gradual decrease thereafter. An exception was GP visits among patients with CVD, with few diagnosis-specific visits before but an increase after. Lower levels of health and functioning tended to be related to more frequent GP and PT visits. An indication of clinically important improvement was found among those with frequent GP visits in the MSD subgroup, and among those with 1-2 GP visits in the CVD subgroup.</p><p><strong>Conclusions: </strong>The diverse relationship between health and functioning, and the use of PHC services at follow-up, may imply that additional factors besides healthcare use explain long-term improvement following rehabilitation.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm39912"},"PeriodicalIF":2.5,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do proprioceptive training strategies with dual-task exercises positively influence gait parameters in chronic stroke? A systematic review.","authors":"Michele Vecchio, Rita Chiaramonte, Alessandro De Sire, Enrico Buccheri, Patrizia Finocchiaro, Dalila Scaturro, Giulia Letizia Mauro, Matteo Cioni","doi":"10.2340/jrm.v56.18396","DOIUrl":"10.2340/jrm.v56.18396","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to assess the impact of proprioceptive training strategies with dual-task exercises on gait in people with chronic stroke.</p><p><strong>Study design: </strong>Systematic review.</p><p><strong>Patients: </strong>Chronic stroke.</p><p><strong>Methods: </strong>Searches were conducted in accordance with PRISMA guidelines and PICOS criteria. PubMed, Web of Science, and Scopus databases were systematically searched from November 2020 to February 2022, for eligible clinical trials. Two independent reviewers thoroughly screened potential articles for relevance and assessed the methodology quality. In accordance with the GRADE, PICOS criteria, and Cochrane risk of bias tools, the authors included articles concerning the effectiveness of dual-task in proprioceptive training on gait parameters in people with chronic stroke.</p><p><strong>Results: </strong>Of 3075 identified studies, 11 articles met the inclusion criteria: 7 were randomized clinical trials, 1 was not randomized, and 3 were observational studies. The overall quality of evidence, assessed using the GRADE framework, was high, indicating a high level of confidence in the systematic review's findings. The papers involved 393 stroke patients; 241 underwent dual-task in proprioceptive training, with 152 participants in other stroke rehabilitation; within the dual-task group, 71 engaged in cognitive tasks, and 170 participated in motor tasks. dual-task in proprioceptive training improved gait speed, cadence, stride time, stride length, and step length. The best effects were observed with training 3 times a week for 4 weeks, with each session lasting 30 minutes, on speed, cadence, stride length, and step length.</p><p><strong>Conclusion: </strong>Current evidence suggests that proprioceptive training strategies with dual-task exercises improved walking abilities in people with chronic stroke. Specifically, it enhanced gait speed, a key indicator of clinical severity.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm18396"},"PeriodicalIF":2.5,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11337222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magnus Fransplass Storli, Marius Steiro Fimland, Harald Kåre Engan, Jon Arne Sandmæl
{"title":"Validity of the Ekblom-Bak Cycle Ergometer Test in Patients with Cardiovascular Disease.","authors":"Magnus Fransplass Storli, Marius Steiro Fimland, Harald Kåre Engan, Jon Arne Sandmæl","doi":"10.2340/jrm.v56.39901","DOIUrl":"10.2340/jrm.v56.39901","url":null,"abstract":"<p><strong>Objective: </strong>To assess the validity of the Ekblom-Bak cycle ergometer test in patients with cardiovascular disease admitted to cardiac rehabilitation.</p><p><strong>Methods: </strong>Estimated peak oxygen consumption from the Ekblom-Bak test was compared with directly measured peak oxygen consumption from a treadmill cardiopulmonary exercise test. Patients completed the cardiopulmonary exercise test first, followed by the Ekblom-Bak test after 24 h rest. Pearson's correlation coefficient (r) was used to establish the correlation between estimated and measured peak oxygen consumption, and Bland-Altman plots with limits of agreement were used to determine the bias between the 2 tests.</p><p><strong>Results: </strong>Twenty-six patients were included in the final analysis. The Ekblom-Bak test significantly overestimated peak oxygen consumption. Agreement between estimated and measured peak oxygen consumption was: bias = 4.3 mL/kg/min (limits of agreement: -4.0-12.6 mL/kg/min).</p><p><strong>Conclusion: </strong>The Ekblom-Bak test overestimated peak oxygen consumption to such an extent that it cannot accurately assess cardiorespiratory fitness in patients with cardiovascular disease. Thus, the cardiopulmonary exercise test remains the test of choice.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":"56 ","pages":"jrm39901"},"PeriodicalIF":2.5,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11334349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}