Journal of Rehabilitation Medicine最新文献

{"title":"A reliable and valid assessment of upper limb movement quality after stroke: the observational Drinking Task Assessment.","authors":"Minnu Jose, Maria Munoz-Novoa, Margit Alt Murphy","doi":"10.2340/jrm.v56.40362","DOIUrl":"10.2340/jrm.v56.40362","url":null,"abstract":"<p><strong>Objective: </strong>To develop and evaluate the reliability and validity of a new observational Drinking Task Assessment (DTA) designed to assess quality of movement in task performance after stroke.</p><p><strong>Design: </strong>Reliability and validity.</p><p><strong>Methods: </strong>The DTA measures movement time and movement quality (smoothness, trunk, shoulder, elbow, and grasp movements) on a 4-level ordinal scale. Thirty participants with chronic stroke were assessed independently by 2 therapists. Intra-class correlation (ICC), standard error of measurement (SEM) and minimal real difference (MRD), weighted kappa, percentage of agreement, and Svensson method were used for reliability assessment. Motion capture-based kinematics and established clinical scales were used to evaluate validity.</p><p><strong>Results: </strong>The absolute SEM and MRD for movement time were 0.4 and 1 s (11%), respectively. The ICC (≥ 0.93) and weighted kappa (0.71-1.0) showed good to excellent agreement for intra- and inter-rater reliability. DTA showed strong correlations with Fugl-Meyer Assessment (0.74), Action Research Arm Test (0.93), and kinematic measures of smoothness (0.93), trunk displacement (0.91), elbow extension (0.73), and shoulder movements (0.56), indicating good construct validity.</p><p><strong>Conclusions: </strong>The new DTA proved to be a reliable and valid tool for assessment of movement quality during task performance after stroke.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11481465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-course for acquiring transfer independence in patients with subacute stroke: a prospective cohort study.","authors":"Shin Kitamura, Yohei Otaka, Shintaro Uehara, Yudai Murayama, Kazuki Ushizawa, Yuya Narita, Naho Nakatsukasa, Daisuke Matsuura, Rieko Osu, Kunitsugu Kondo, Sachiko Sakata","doi":"10.2340/jrm.v56.40055","DOIUrl":"10.2340/jrm.v56.40055","url":null,"abstract":"<p><strong>Objective: </strong>To clarify the time-course of longitudinal changes in the independence level of subtasks composing bed-wheelchair transfer among patients with stroke.</p><p><strong>Design: </strong>Single-institution prospective cohort study.</p><p><strong>Patients: </strong>A total of 137 consecutive post-stroke patients using wheelchair on admission to the subacute rehabilitation wards.</p><p><strong>Methods: </strong>The independence degree in each of the 25 transfer-related subtasks was assessed using the Bed-Wheelchair Transfer Tasks Assessment Form on a three-level scale every two weeks, from admission to the endpoint (either discharge or when achieving independent transfer). Patients were classified based on admission and endpoint assessment form scores using two-step cluster analysis.</p><p><strong>Results: </strong>Patients were classified into three clusters. The first cluster included 50 patients who exhibited a greater independence level in all subtasks on admission (52.0-100% of patients performed each subtask independently) and at the endpoint (64.0-100%). The second included 30 patients who showed less independence on admission (0-27.8%) but achieved greater independence levels at the endpoint (44.4-97.2%). The third included 51 patients whose independence level remained low in many subtasks from admission (0-5.8%) until the endpoint (0-29.4%).</p><p><strong>Conclusion: </strong>The independence level and its changing process during transfer were categorized into three time-courses, each requiring different intervention strategies.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11481307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Positive effects of lower extremity constraint-induced movement therapy on balance, leg strength and dual-task ability in stroke patients: a longitudinal cohort study.","authors":"Annika Sefastsson, Ingela Marklund, Håkan Littbrand, Per Wester, Britt-Marie Stålnacke, Ann Sörlin, Birgitta Langhammer, Per Liv, Xiaolei Hu","doi":"10.2340/jrm.v56.24168","DOIUrl":"10.2340/jrm.v56.24168","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether high-intensity lower extremity constraint-induced movement therapy can improve balance, leg strength, and dual-task ability.</p><p><strong>Design: </strong>A longitudinal cohort study in a real-world outpatient clinic.</p><p><strong>Patients: </strong>147 community-dwelling participants in the subacute and chronic poststroke phases.</p><p><strong>Methods: </strong>Participants received lower extremity constraint-induced movement therapy for 6 hours/day during 2 consecutive weeks, including balance, strength, and functional training. The Berg Balance Scale (BBS), Single-Leg-Stance (SLS) bilaterally, one Repetition Maximum (1RM) in a leg press, symmetry of leg strength (Diff-1RM), Timed Up and Go (TUG), and the TUG Manual test were assessed before, after, and 3 months after lower extremity constraint-induced movement therapy.</p><p><strong>Results: </strong>Compared with preintervention data, statistically significant improvements after lower extremity constraint-induced movement therapy (p < 0.001) were demonstrated for balance with an absolute value in BBS at 1.9 points (effect size 0.38) and SLS at 2.4 s (effect size 0.24), and for leg strength at 10.2 kg (effect size 0.54) for the affected leg. Diff 1RM decreased significantly at 5.8 kg (effect size 0.39) and improvements on dual-task ability at 2.7 s were significant (effect size 0.14). The effects persisted at the 3-month follow-up.</p><p><strong>Conclusions: </strong>High-intensity lower extremity constraint-induced movement therapy may be a feasible treatment option for middle-aged stroke patients to affect balance, leg strength, and dual-task ability positively in an out-patient clinical setting.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immersive visualization of movement in patients with hemophilic ankle arthropathy. Multicenter, single-blind, randomized clinical trial.","authors":"Roberto Ucero-Lozano, Raúl Pérez-Llanes, Rubén Cuesta-Barriuso, Elena Donoso-Úbeda","doi":"10.2340/jrm.v56.40775","DOIUrl":"10.2340/jrm.v56.40775","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of immersive movement observation in adult patients with haemophilic ankle arthropathy.</p><p><strong>Design: </strong>Multicentre, single-blind, randomized clinical trial.</p><p><strong>Subjects: </strong>48 patients with haemophilia.</p><p><strong>Methods: </strong>Patients were randomly allocated to 2 groups (180º immersive video-based visualization of movement and a control group with no intervention). Twenty-eight consecutive 15-min home sessions, 1 per day, of immersive visualization of ankle flexion-extension movement were carried out. Three evaluations were performed: pretreatment (T0), post-intervention (T1), and at 16 weeks' follow-up (T2). The primary variable was joint-pain intensity (visual analogue scale). The secondary variables were conditioned pain modulation (Conditioned Pain Modulation Index), pressure pain threshold (pressure algometer), range of motion (goniometry) and kinesiophobia (Tampa Scale of Kinesiophophia).</p><p><strong>Results: </strong>There were intergroup differences in pain intensity (F = 37.14; p < 0.001), conditioned pain modulation (F = 5.40; p = 0.006), and dorsal (F = 19.17; p < 0.001) and plantar (F = 9.27; p<0.001) ankle flexion. More than 50% of experimental group patients exhibited changes exceeding the minimum detectable change in pain intensity (MDC = 0.43), and the pressure pain threshold in the extensor carpi radialis longus muscle (MDC = 1.34) and malleolus (MDC = 4.93).</p><p><strong>Conclusions: </strong>180º immersive video-based visualization of movement can improve the intensity of pain, conditioned pain modulation, and ankle range of motion in patients with haemophilic ankle arthropathy.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The veracity function: integrity, and comprehensiveness of evidence.","authors":"Antti Malmivaara","doi":"10.2340/jrm.v56.40350","DOIUrl":"10.2340/jrm.v56.40350","url":null,"abstract":"","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of a new video observational training method (intensive visual simulation) for motor recovery in the upper limb in subacute stroke: a feasibility and proof-of-concept study.","authors":"Etienne Ojardias, Ahmed Adham, Hugo Bessaguet, Virginie Phaner, Diana Rimaud, Pascal Giraux","doi":"10.2340/jrm.v56.36119","DOIUrl":"10.2340/jrm.v56.36119","url":null,"abstract":"<p><strong>Objective: </strong>To demonstrate the feasibility and efficacy  of a new video-observation training method (intensive visual simulation) to improve upper limb function.</p><p><strong>Design: </strong>Small sample, randomized, evaluator-blind, monocentric study.</p><p><strong>Patients: </strong>Seventeen early subacute ischaemic stroke patients with complete hemiplegia were  randomly assigned to the therapeutic group (n = 8) or control group (CG, n = 9).</p><p><strong>Methods: </strong>Thirty sessions of intensive visual simulation combined with corrected visual feedback (therapeutic group) or uncorrected visual feedback (control group) were performed over 6 weeks on top of a standard rehabilitation programme.</p><p><strong>Main outcome measure: </strong>400-point hand assessment test (400p-HA).</p><p><strong>Secondary outcome measures: </strong>Box and Blocks (B&B), Purdue Pegboard test, Minnesota.</p><p><strong>Results: </strong>The 400p-HA test improved significantly from T0 to 6 months for both groups, with a significant difference between groups at 3 months (MW-UT p = 0.046) and 4 months (MW-UT p = 0.046) in favour of the therapeutic group. One-phase exponential modelling of 400p-HA showed a greater plateau for the therapeutic group (F test p = 0.0021). There was also faster recovery of the ability to perform the B&B tests for the therapeutic group (log-rank test p = 0.03).</p><p><strong>Conclusion: </strong>This study demonstrated the feasibility and potential efficacy of an intensive visual simulation training programme to improve upper limb  function in subacute stroke patients. A larger study is needed to confirm these results.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11445588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of mirror therapy in post-traumatic complex regional pain syndrome type-1: a randomized controlled study.","authors":"Elif Can Özdemir, Atilla H Elhan, Ayşe A Küçükdeveci","doi":"10.2340/jrm.v56.40417","DOIUrl":"10.2340/jrm.v56.40417","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effects of mirror therapy applied in addition to routine rehabilitation on clinical outcomes in post-traumatic complex regional pain syndrome type 1.</p><p><strong>Design: </strong>Single-blind randomized controlled trial.</p><p><strong>Subjects: </strong>Patients with trauma-induced complex regional pain syndrome type 1 of the hand receiving outpatient rehabilitation.</p><p><strong>Methods: </strong>Patients were randomized into mirror therapy and control groups. All patients received routine physical therapy and rehabilitation for 20 sessions (5 sessions/week, for 4 weeks). The mirror group received additional mirror therapy at each session. The primary outcome was pain intensity by numeric rating scale. Secondary outcomes were grip/pinch strength, hand/wrist circumference, dexterity, hand activities, and health-related quality of life. All assessments were performed before and immediately after the treatment, and 4 weeks later at follow-up.</p><p><strong>Results: </strong>Forty patients were enrolled, 20 in each group. Both groups revealed statistically significant improvements from therapy regarding pain, grip/pinch strength, wrist circumference, dexterity, and hand activities (p <  0.05). When groups were compared regarding the improvements in assessment parameters, no statistically significant difference was found between the 2 groups in any of the outcomes (p > 0.05).</p><p><strong>Conclusion: </strong>Mirror therapy applied in addition to routine therapy in post-traumatic complex regional pain syndrome type 1 did not provide extra benefit to the improvement of pain, function, and other clinical outcomes.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing upper extremity muscle strength in individuals with spinal cord injury using low-intensity blood flow restriction exercise.","authors":"Babak Shadgan, Mehdi Nourizadeh, Yekta Saremi, Leila Baktash, Stefan Lazarevic","doi":"10.2340/jrm.v56.40608","DOIUrl":"10.2340/jrm.v56.40608","url":null,"abstract":"<p><strong>Objectives: </strong>This study explores the feasibility and effects of low-intensity blood flow restriction exercise on forearm muscle strength and function in individuals with spinal cord injury.</p><p><strong>Study design: </strong>Pilot randomized clinical trial.</p><p><strong>Patients and methods: </strong>Ten male and female adult participants with chronic cervical and thoracic spinal cord injury underwent an 8-week low-intensity blood flow restriction exercise programme that targeted forearm muscles. Each participant's contralateral forearm served as the control. Grip strength was the primary outcome measure, and participants also provided qualitative feedback on their experiences.</p><p><strong>Results: </strong>The study revealed a significant increase in participants' forearm muscle strength on the experimental side engaged in low-intensity blood flow restriction training, with an average strength gain of 7.5 ± 0.36 kg after 16 exercise sessions (Cohen's d = -6.32, 95% CI -8.34, -6.68). In comparison, the control side, following a conventional high- intensity exercise regimen without BFR, showed a more modest strength increase of 4.4 ± 0.67 kg. A mean Patient's Global Impression of Change score of 2.2 reflected overall improvements in participants' daily activities and health status.</p><p><strong>Conclusion: </strong>This study highlights the feasibility and effectiveness of low-intensity blood flow restriction exercise as a safe and promising approach to enhancing forearm muscle strength in individuals with spinal cord injury. The observed positive outcomes, coupled with a high level of participant satisfaction, underscore the potential of this innovative method to significantly improve limb muscle strength, thereby contributing to greater functional independence in this population.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease and obstructive sleep apnea; a randomized controlled trial.","authors":"Honghua Shen, Yiming Xu, Yin Zhang, Lei Ren, Rui Chen","doi":"10.2340/jrm.v56.23757","DOIUrl":"10.2340/jrm.v56.23757","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of pulmonary rehabilitation in the outcomes of patients with chronic obstructive pulmonary disease-obstructive sleep apnoea overlap syndrome patients who used positive airway pressure.</p><p><strong>Design: </strong>Prospective randomized controlled single- blind trial.</p><p><strong>Patients: </strong>A total of 79 patients with chronic obstructive pulmonary disease-obstructive sleep apnoea overlap syndrome were randomly assigned to either the intervention group (n = 40) or control group (n = 39).</p><p><strong>Methods: </strong>All patients consistently adhered to positive airway pressure therapy every night from enrolment in the study, while intervention group patients received additional moderate-intensity aerobic exercise for 20 weeks. Pre- and post-intervention measurements included the 6-Minute Walk Test, Barthel Index, body mass index, fat mass, free fat mass, forced expiratory volume in 1 s (FEV1), FEV1%predicted, modified Medical Research Council, and polysomnography parameters.</p><p><strong>Results: </strong>After 20 weeks, the intervention group exhibited statistically significant improvements in 6MWD, Barthel Index, body mass index, fat mass, and modified Medical Research Council compared with control group (all p < 0.01). In addition, the intervention group showed a significantly lower percentage of total sleep time with oxygen saturation < 90% (p = 0.013) and higher lowest nocturnal oxygen saturation (p = 0.008) than the control group. However, there was no significant difference in FEV1 %predicted between the 2 groups.</p><p><strong>Conclusion: </strong>Pulmonary rehabilitation incorporating moderate-intensity aerobic exercise could improve physical endurance and motor abilities in individuals with chronic obstructive pulmonary disease-obstructive sleep apnoea overlap syndrome, while also improving anamnestic dyspnoea, body composition, and sleep-disordered breathing.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported mental health in hospitalized patients with COVID-19: A 1-year follow-up.","authors":"Linda Ashman Kröönström, David Krabbe, Alexandra Larsson, Lena Rafsten, Annie Palstam, Katharina S Sunnerhagen, Hanna C Persson","doi":"10.2340/jrm.v56.40654","DOIUrl":"10.2340/jrm.v56.40654","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to longitudinally follow self-reported symptoms of depression, anxiety, post-traumatic stress disorder, and fatigue during the first year after hospitalization because of COVID-19.</p><p><strong>Design: </strong>The study was an observational longitudinal study.</p><p><strong>Methods and participants: </strong>Between July 2020, and February 2021, 211 patients aged ≥ 18 years, hospitalized ≥ 5 days at 5 hospitals in Region Västra Götaland, who had COVID-19, and were non-contagious (at study enrolment) were included in the baseline assessment. Of these, 168 (79.6%) patients completed mental health questionnaires at a 3-month follow-up, and 172 (83.1%) at a 12-month follow-up. A total of 120 (56.9%) participants who completed at least 1 questionnaire at both the 3- and 12-month follow-ups were analysed; the majority were male (n = 78, 65.0%).</p><p><strong>Results: </strong>There was an improvement in all patients from 3 to 12 months on the fatigue subscales \"reduced activity\" (p = 0.02) and \"physical fatigue\" (p = 0.04). No other significant mental health improvements were found. At 12 months, 34 (28.4%) were classified as having anxiety symptoms, 29 (24.1%) as having depression symptoms, and 40 (33.3%) had symptoms of probable post-traumatic stress disorder.</p><p><strong>Conclusions: </strong>Participants in the present study did not report full mental health recovery 1 year after hospitalization for COVID-19.</p>","PeriodicalId":54768,"journal":{"name":"Journal of Rehabilitation Medicine","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}