Ophthalmic Surgery Lasers & Imaging最新文献_第2页

Long-term monitoring of age-related macular degeneration with preferential hyperacuity perimetry. 使用优先的高敏度验光法长期监测老年性黄斑变性。

Ophthalmic Surgery Lasers & Imaging Pub Date : 2010-11-01 Epub Date: 2010-08-30 DOI: 10.3928/15428877-20100830-05

Michael Stur, Yair Manor

{"title":"Long-term monitoring of age-related macular degeneration with preferential hyperacuity perimetry.","authors":"Michael Stur, Yair Manor","doi":"10.3928/15428877-20100830-05","DOIUrl":"https://doi.org/10.3928/15428877-20100830-05","url":null,"abstract":"Background and objective: To estimate the efficacy and usability of preferential hyper-acuity perimetry (PHP) for monitoring patients with high-risk intermediate age-related macular degeneration (AMD).Patients and methods: A long-term, observational, prospective case series of patients with intermediate AMD who underwent fluorescein angiography at recruitment. Eyes were examined every 3 months with PHP, visual acuity, and biomicroscopy. Optical coherence tomography (OCT) imaging was performed when PHP was outside normal limits. In case of suspected findings in OCT, fluorescein angiography was also performed. Patients diagnosed as having choroidal neovascularization (CNV) were offered anti-vascular endothelial growth factor therapy.Results: Twenty-six eyes (25 patients) were monitored for a mean follow-up period of 600 days. Of the 172 PHP tests done by these 26 eyes with intermediate AMD, 158 were within normal limits yielding a false-positive rate of 8.1%. Three of 4 eyes that converted to CNV had PHP test results outside normal limits before or on the day of diagnosis.Conclusion: PHP is useful for detecting CNV in regularly monitored eyes with intermediate AMD while maintaining a low false-positive rate.","PeriodicalId":54675,"journal":{"name":"Ophthalmic Surgery Lasers & Imaging","volume":" ","pages":"598-606"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40066511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Bevacizumab for the treatment of pediatric retinal and choroidal diseases. 贝伐单抗用于治疗儿童视网膜和脉络膜疾病。

Ophthalmic Surgery Lasers & Imaging Pub Date : 2010-11-01 Epub Date: 2010-08-30 DOI: 10.3928/15428877-20100830-03

Robert A Sisk, Audina M Berrocal, Thomas A Albini, Timothy G Murray

{"title":"Bevacizumab for the treatment of pediatric retinal and choroidal diseases.","authors":"Robert A Sisk, Audina M Berrocal, Thomas A Albini, Timothy G Murray","doi":"10.3928/15428877-20100830-03","DOIUrl":"https://doi.org/10.3928/15428877-20100830-03","url":null,"abstract":"Background and objective: To determine the efficacy of off-label intravitreal bevacizumab (IVB) for the treatment of pediatric retinal and choroidal vascular diseases.Patients and methods: Retrospective, non-comparative, open-label, interventional, consecutive case series of all patients younger than 18 years treated with off-label IVB at a single center from January 1, 2005, to January 1, 2008. Primary outcome measures with best-corrected visual acuity by age-appropriate testing and central macular thickness by time-domain optical coherence tomography.Results: Thirty-five eyes of 33 patients were treated with IVB alone or in combination with other treatments for choroidal neovascularization, Coats' disease, familial exudative vitreoretinopathy, and various other indications. IVB was used in 24 eyes to reduce excess retinal fluid and exudation. Mean Snellen visual acuity improved from 20/170 at baseline to 20/100 at 1 month (P = .006), 20/80 at 3 months (P = .006), and 20/50 at 6 months (P = .023). Central macular thickness improved from 356 μm at baseline to 287 μm at 6 months (P = .028). IVB was used in 11 eyes to control peripheral retinal neovascularization and iris rubeosis. Although IVB reduced vascular engorgement, it did not prevent the progression of preretinal tractional forces. Mean visual acuity was maintained at each time point. No systemic or ocular adverse events were directly attributable to IVB in any patient.Conclusion: IVB reduced vascular leakage and temporarily regressed pathologic neovascularization of the choroid, retina, and iris in this series of pediatric patients. Further prospective studies are warranted.","PeriodicalId":54675,"journal":{"name":"Ophthalmic Surgery Lasers & Imaging","volume":" ","pages":"582-92"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40066512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Efficacy of different excimer laser techniques in the management of recurrent corneal erosions. 不同准分子激光治疗复发性角膜糜烂的疗效。

Ophthalmic Surgery Lasers & Imaging Pub Date : 2010-11-01 Epub Date: 2010-08-30 DOI: 10.3928/15428877-20100830-01

Werner W Hütz, Oliver Stachs, Fritz Hengerer, Berthold Eckhardt

{"title":"Efficacy of different excimer laser techniques in the management of recurrent corneal erosions.","authors":"Werner W Hütz, Oliver Stachs, Fritz Hengerer, Berthold Eckhardt","doi":"10.3928/15428877-20100830-01","DOIUrl":"https://doi.org/10.3928/15428877-20100830-01","url":null,"abstract":"Background and objective: To investigate the efficacy of two excimer laser techniques for recurrent corneal erosions (RCEs).Patients and methods: Of 100 patients with RCEs not responding to common treatments, 50 received transepithelial (group 1) and 50 received subepithelial (group 2) treatment of 20 pulses of a 193-nm excimer laser (170 J/cm(2)). Postoperative follow-up occurred at 4 and 52 weeks. Outcome measures were frequency of RCEs, haze formation, and refractive changes.Results: At first follow-up, 7 patients (14%) in each group displayed recurrence. At second follow-up, 12 patients in group 1 (24%) and 10 patients in group 2 (20%) had RCE. Follow-up recurrence risk was 6% to 27% in both groups at 4 weeks and 13% to 38% in group 1 and 10% to 34% in group 2 at 52 weeks. The spherical equivalent remained unaffected in group 1, but a statistically significant change was observed in group 2.Conclusion: Excimer laser treatment (transepithelial and subepithelial) of RCEs can be performed successfully on the intact epithelium without adjunct therapy or pain. The transepithelial technique is a simple and relatively painless way to reduce the rate of RCE and is equivalent to the well-established subepithelial treatment.","PeriodicalId":54675,"journal":{"name":"Ophthalmic Surgery Lasers & Imaging","volume":" ","pages":"635-41"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40066422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Comparison of stereo disc photographs and alternation flicker using a novel matching technology for detecting glaucoma progression. 用一种新的匹配技术检测青光眼的进展，比较立体光盘照片和交替闪烁。

Ophthalmic Surgery Lasers & Imaging Pub Date : 2010-11-01 Epub Date: 2010-08-30 DOI: 10.3928/15428877-20100830-02

Nathan M Radcliffe, Mitra Sehi, Ira B Wallace, David S Greenfield, Theodore Krupin, Robert Ritch

{"title":"Comparison of stereo disc photographs and alternation flicker using a novel matching technology for detecting glaucoma progression.","authors":"Nathan M Radcliffe, Mitra Sehi, Ira B Wallace, David S Greenfield, Theodore Krupin, Robert Ritch","doi":"10.3928/15428877-20100830-02","DOIUrl":"https://doi.org/10.3928/15428877-20100830-02","url":null,"abstract":"Background and objective: To compare agreement of automated alternation flicker and serial stereophotograph inspection for detection of progressive glaucoma.Patients and methods: Serial photographs of patients with glaucoma with at least 36 months of follow-up and perimetry every 4 months were assessed by four graders using predefined criteria with both flicker and stereophotography. The main outcome measure was progressive neuroretinal rim deterioration as identified by each technique.Results: Forty eyes (20 patients) were included and 12 eyes progressed with perimetry. Using stereophotography, the overall agreement (kappa ± standard error) was 0.19 ± 0.06 for rim change, 0.78 ± 0.06 for disc hemorrhage, and -0.04 ± 0.06 for vessel movement. Using flicker, the overall agreement was similar for rim change (0.28 ± 0.06; P = .29), worse for disc hemorrhage (0.43 ± 0.06; P < .001), and better for vessel movement (0.22 ± 0.06; P = .002). The agreement between perimetric and disc progression was similar using stereophotography (0.10 ± 0.05) and flicker (0.19 ± 0.05; P = .20).Conclusion: Agreement between flicker and stereophotography was similar.","PeriodicalId":54675,"journal":{"name":"Ophthalmic Surgery Lasers & Imaging","volume":" ","pages":"629-34"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40066419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Retinal layer thickness changes in eyes with preserved visual acuity and diffuse diabetic macular edema on optical coherence tomography. 光学相干断层扫描显示保留视力和弥漫性糖尿病黄斑水肿患者视网膜层厚度的变化。

Ophthalmic Surgery Lasers & Imaging Pub Date : 2010-11-01 Epub Date: 2010-08-30 DOI: 10.3928/15428877-20100830-04

Gábor Márk Somfai, Erika Tátrai, Mária Ferencz, Carmen A Puliafito, Delia Cabrera Debuc

{"title":"Retinal layer thickness changes in eyes with preserved visual acuity and diffuse diabetic macular edema on optical coherence tomography.","authors":"Gábor Márk Somfai, Erika Tátrai, Mária Ferencz, Carmen A Puliafito, Delia Cabrera Debuc","doi":"10.3928/15428877-20100830-04","DOIUrl":"https://doi.org/10.3928/15428877-20100830-04","url":null,"abstract":"Background and objective: Diabetic macular edema has several patterns on optical coherence tomography. This retrospective study aimed to assess which retinal layers show thickness changes in type 1 diffuse diabetic macular edema with preserved vision.Patients and methods: Eleven eyes with diffuse diabetic macular edema on optical coherence tomography and eight control eyes with 20/20 best-corrected visual acuity were enrolled. Optical coherence tomography images were segmented using an algorithm of the authors' design (OCTRIMA): regional thickness data in the central area, pericentral rings, and peripheral rings were obtained for the retinal cellular layers.Results: The retinal nerve fiber layer showed no changes, the ganglion cell and inner plexiform composite layer and the ganglion cell complex were thicker only in the pericentral regions, and all other layers were thicker in all regions in diffuse diabetic macular edema. Macular thickness was normal in the peripheral region.Conclusion: The results show that the outer retina in the foveal area is the most affected in diffuse diabetic macular edema.","PeriodicalId":54675,"journal":{"name":"Ophthalmic Surgery Lasers & Imaging","volume":" ","pages":"593-7"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40066514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

A Newborn With Lipemia Retinalis 新生儿视网膜脂血症1例

Ophthalmic Surgery Lasers & Imaging Pub Date : 2003-05-01 DOI: 10.3928/1542-8877-20030501-13

M. Ozdemir, A. Bay, T. Yaşar, A. Çınal

引用次数: 2