Efficacy of different excimer laser techniques in the management of recurrent corneal erosions.

Ophthalmic Surgery Lasers & Imaging Pub Date : 2010-11-01 Epub Date: 2010-08-30 DOI:10.3928/15428877-20100830-01

Werner W Hütz, Oliver Stachs, Fritz Hengerer, Berthold Eckhardt

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引用次数: 5

Abstract

Background and objective: To investigate the efficacy of two excimer laser techniques for recurrent corneal erosions (RCEs).

Patients and methods: Of 100 patients with RCEs not responding to common treatments, 50 received transepithelial (group 1) and 50 received subepithelial (group 2) treatment of 20 pulses of a 193-nm excimer laser (170 J/cm(2)). Postoperative follow-up occurred at 4 and 52 weeks. Outcome measures were frequency of RCEs, haze formation, and refractive changes.

Results: At first follow-up, 7 patients (14%) in each group displayed recurrence. At second follow-up, 12 patients in group 1 (24%) and 10 patients in group 2 (20%) had RCE. Follow-up recurrence risk was 6% to 27% in both groups at 4 weeks and 13% to 38% in group 1 and 10% to 34% in group 2 at 52 weeks. The spherical equivalent remained unaffected in group 1, but a statistically significant change was observed in group 2.

Conclusion: Excimer laser treatment (transepithelial and subepithelial) of RCEs can be performed successfully on the intact epithelium without adjunct therapy or pain. The transepithelial technique is a simple and relatively painless way to reduce the rate of RCE and is equivalent to the well-established subepithelial treatment.

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不同准分子激光治疗复发性角膜糜烂的疗效。

背景与目的:探讨两种准分子激光治疗复发性角膜糜烂(RCEs)的疗效。患者和方法:在100例常规治疗无效的rce患者中，50例接受经上皮治疗(1组)，50例接受上皮下治疗(2组)，20次脉冲193 nm准分子激光(170 J/cm(2))。术后随访时间分别为4周和52周。结果测量为rce频率、雾霾形成和屈光变化。结果:首次随访时，两组均有7例(14%)出现复发。第二次随访时，1组12例(24%)和2组10例(20%)患者出现RCE。4周时两组随访复发风险为6% - 27%，52周时1组为13% - 38%，2组为10% - 34%。在第1组中，球形当量未受影响，但在第2组中观察到统计学上显著的变化。结论:准分子激光治疗rce(经上皮和上皮下)可以在完整的上皮上成功进行，无需辅助治疗或疼痛。经上皮技术是一种简单且相对无痛的降低RCE发生率的方法，相当于公认的上皮下治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmic Surgery Lasers & Imaging 医学-外科

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Ophthalmic Surgery, Lasers and Imaging, an official publication of ARVO/ISIE, provides clinically valuable, practical articles in the field of ophthalmology on a bimonthly basis. The Journal publishes original, peer-reviewed articles that delve into the entire spectrum of ophthalmic surgery and treatment, including experimental science, surgical techniques, and video surgical clips. Subscribers can also benefit from our featured On Line Advanced Release—read articles before they appear in the print issue!