Environmental Science and Pollution Research最新文献

{"title":"Assessing the efficacy of electrocoagulation process for polypropylene microplastics removal from wastewater: Optimization through TOPSIS approach","authors":"Pranat Jain,&nbsp;Kunwar D. Yadav,&nbsp;Bharat Z. Dholakiya","doi":"10.1007/s11356-025-36410-7","DOIUrl":"10.1007/s11356-025-36410-7","url":null,"abstract":"<div><p>Emerging contaminants, microplastics in particular, pose a substantial risk to human health and the environment. Conventional treatments fail to incorporate focused approaches to eliminate them. This research comprehensively evaluated the effectiveness of electrocoagulation as a techno-economic method for removal of microplastics from water. The research meticulously investigated the effects of various electrode combinations composed of SS (stainless steel) and Al (aluminium) with possible combination as Al-Al, Al-SS, SS-Al and SS. Out of the various combinations considered, it was discovered that the Al–Al coupling demonstrated exceptional efficacy of 95.54% in the elimination of microplastics, with a concurrent reduction in energy consumption. The initial pH value was found to be a crucial parameter, as evidenced by the highest removal efficacy of 92.80% observed at a near neutral alkaline pH of 8. However, in order to determine economic efficacy, it is necessary to consider additional variables including energy consumption, electrode utilisation, and post-treatment conductivity. In order to address the intricacy presented by a multitude of parameters and criteria, it is critical to employ multi-criteria decision-making tools such as Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS), which has demonstrated efficacy in real-world scenarios. The optimal electrolyte concentration, as determined by TOPSIS analysis, is 0.5 g/L. Furthermore, the TOPSIS analysis underscored the superior performance of punched hollow cylindrical electrode. The investigation conducted a thorough assessment of the impact of time period and concluded that a 100-min interval offers the highest efficacy in removing microplastics. At an input concentration of 2 g/L, this enhanced optimized system demonstrated outstanding competence in removing microplastics of three different sizes 45–90 μm, 90–180 μm, and 180–355 μm, with the removal efficiencies of 89.80%, 93.12%, and 94.08%, respectively. The current study introduces a pragmatic and exceptionally efficient approach to tackle the urgent problem of microplastic pollution in aquatic ecosystems.</p></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"12066 - 12085"},"PeriodicalIF":5.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron oxide-MXene-based composite for the removal of copper ions from wastewater","authors":"Riddhi Patel,&nbsp;Monika Patel,&nbsp;Ranjit D. Mohili,&nbsp;Kajal Mahabari,&nbsp;Arvind H. Jadhav,&nbsp;Swapnil Dharaskar,&nbsp;M. A. Shabiimam,&nbsp;Nitin Chaudhari","doi":"10.1007/s11356-025-36413-4","DOIUrl":"10.1007/s11356-025-36413-4","url":null,"abstract":"<div><p>The present work primarily aims to evaluate the adsorption properties of MXene and its nanocomposite, Fe₃O₄@MXene, for removing heavy metal ions from industrial wastewater. Two-dimensional (2D) MXene nanosheets were combined with Fe₃O₄ nanoparticles through a hydrothermal synthesis process to create the Fe₃O₄@MXene nanocomposite. Characterization revealed that Fe₃O₄ nanoparticles self-assembled onto MXene sheets, forming a structure that enhanced the 2D structure of MXene, with nanoparticles uniformly distributed throughout the nanosheet network. Performance experiments demonstrated that Fe₃O₄@MXene nanocomposite significantly outperformed pristine MXene in adsorbing heavy metal ions from wastewater. Notably, Fe₃O₄@MXene nanocomposite achieved an 83% removal efficiency for Cu ions, highlighting its potential as a highly efficient adsorbent in industrial wastewater treatment. This work underscores the viability of Fe₃O₄@MXene for heavy metal remediation, marking an important step toward practical environmental applications of MXene-based materials.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"12108 - 12120"},"PeriodicalIF":5.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of an integrated system composed of native soil amended with ZVI/FeS nanoparticles-based technosols and a bioreactor for the treatment of acid rock drainage","authors":"Aracely Zambrano-Romero,&nbsp;Erika Llumiquinga,&nbsp;Natalia Carpintero-Salvador,&nbsp;Gabriel Trueba,&nbsp;Dario Xavier Ramirez-Villacis,&nbsp;Antonio Leon-Reyes,&nbsp;Darío Bolaños,&nbsp;Margarita Mayacela,&nbsp;Rodny Peñafiel,&nbsp;Luis Cumbal,&nbsp;Valeria Ochoa-Herrera","doi":"10.1007/s11356-025-36424-1","DOIUrl":"10.1007/s11356-025-36424-1","url":null,"abstract":"<div><p>We assessed combined, low-cost physical–chemical and biological treatment system for the remediation of acid rock drainage (ARD). Two columns composed of native soil amended with zero valent iron and iron sulfide (ZVI/FeS) nanoparticles-based Technosols were connected to a sulfate-reducing (SR) bioreactor; this integrated treatment system was fed with ARD obtained from mines in El Oro, Ecuador. A control sulfate-reducing bioreactor fed directly with ARD was run in parallel. The bioreactors were operated dynamically for four periods, and every 21 days, the fraction of ARD in the influent was increased stepwise from 25 to 100%. The integrated treatment system demonstrated superior removal efficiencies for Fe (99%), As (99.9%), Cd (99%), Cu (98%), Mn (91%), and Zn (99.9%), while both bioreactors achieved similar sulfate reduction (50–52%) and raised ARD pH from 2.75 to ~ 8. However, the ZVI/FeS nanoparticles-based Technosols significantly improved the removal of As (99.9% vs. 68%) and Mn (91% vs. 71%), compared to the control bioreactor. Molecular ecology analysis of the biomass in the bioreactors using 16S rRNA sequencing revealed that higher ARD concentrations enhanced sulfidogenesis, promoting beneficial interactions within communities in the sulfate-reducing niche. This study highlights the value of the ZVI/FeS nanoparticles-based Technosols in optimizing ARD bioremediation, offering a promising solution for mining effluent management in low-middle-income countries (LMIC). </p><h3>Graphical Abstract</h3><p>Performance of an integrated system composed of native soil amended with ZVI/FeS nanoparticles-based Technosols and a bioreactor for the treatment of acid rock drainage. Created in BioRender.com 02/10/2024</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"12049 - 12065"},"PeriodicalIF":5.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variability of the optical signatures of dissolved organic matter in soils of different mangrove stands (Ouvéa, New Caledonia)","authors":"Naïna Mouras,&nbsp;Hugues Lemonnier,&nbsp;Thomas Crossay,&nbsp;Kapeliele Gututauava,&nbsp;Maximilien Mathian,&nbsp;Sarah Louise Robin,&nbsp;Océane Tardivel,&nbsp;Cyril Marchand","doi":"10.1007/s11356-025-36373-9","DOIUrl":"10.1007/s11356-025-36373-9","url":null,"abstract":"<div><p>Mangrove ecosystems are known to play a key role in the global carbon cycle, due to their productivity and their ability for carbon sequestration both in the biomass and in the soil. In the latter, various geochemical processes lead to the production of dissolved organic matter (DOM) that can be exported through tidal pumping and then constitute an important source of organic carbon for adjacent ecosystems. DOM characteristics, and their variabilities, within mangrove soils depend on several factors, including the mangrove species, yet these variations and their origin still need to be precisely constrained. This study examined DOM sources in soils of a carbonate atoll mangrove (Ouvéa, New Caledonia), focusing on two tree species, <i>Rhizophora apiculata</i> and <i>Bruguiera gymnorhiza</i>, at different growth stages. We analysed porewater properties and DOM optical characteristics through spectroscopic and EEM-PARAFAC methods. Our results indicate distinct TOC and DOC concentrations across species, with mature <i>B. gymnorhiza</i> soils showing the highest TOC content (~ 30%) but the lowest DOC content (32 mg L⁻¹). These differences seem not to be directly related to site physicochemical conditions (redox, pH, salinity) but may rather reflect differences in DOM sources and production, notably due to different symbiotic relationships with mycorrhizal fungi, which influence microbial activity and organic matter diagenesis. DOM absorbance patterns also varied significantly between species: Beneath <i>R. apiculata</i>, DOM had higher protein-like and fulvic-like fluorescence, indicating fresher organic matter, while beneath <i>B. gymnorhiza</i>, especially in mature stands, DOM was more humified, suggesting older OM because of a possible long-term accumulation due to the basin-like morphology of this site.</p></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"12086 - 12107"},"PeriodicalIF":5.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11356-025-36373-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of calcium acetate in promoting Vibrio campbellii bioluminescence and alleviating salinity stress in Episcia cupreata","authors":"Nattida Chonjoho,&nbsp;Paitip Thiravetyan,&nbsp;Nimaradee Boonapatcharoen,&nbsp;Rujira Dolphen","doi":"10.1007/s11356-025-36419-y","DOIUrl":"10.1007/s11356-025-36419-y","url":null,"abstract":"<div><p>This study examines the role of calcium in regulating the bioluminescence of <i>Vibrio campbellii</i> PSU5986 and its potential to alleviate salt stress in plants, which has implications for developing light-emitting plants (LEPs). The effects of organic calcium acetate (C₄H₆CaO₄) were compared to inorganic calcium chloride (CaCl₂) and skim milk regarding their impact on bacterial bioluminescence and plant physiology. While skim milk induced the highest initial luminescence, both C₄H₆CaO₄ and CaCl₂ prolonged light emission for over 16 h. Notably, C₄H₆CaO₄ prevented leaf shrinkage, a condition observed with inorganic salts after 24 h. Periodic supplementation of C₄H₆CaO₄ (every 6 h) improved bacterial immobilization and colonization, extending luminescence over 4 cycles (24 h). Bacterial enumeration revealed colonization densities of approximately 6.82 × 10⁶ CFU cm⁻² within leaf tissues and 5.22 × 10¹¹ CFU cm⁻² on the leaf surface. Quantitative PCR analysis indicated that <i>luxG</i> exhibited significantly higher copy numbers than <i>luxA</i> and <i>luxC</i>, highlighting its critical role in bioluminescence through flavin reductase activity. Additionally, C₄H₆CaO₄ reduced salt-induced oxidative stress by increasing chlorophyll levels while decreasing carotenoid (40.00%), anthocyanin (36.94%), proline (14.13%), and malondialdehyde (21.84%) accumulation compared to NaCl-treated plants. These findings emphasize the potential of C₄H₆CaO₄ to sustain bacterial luminescence and enhance plant resilience, contributing to the advancement of LEP technology as a sustainable bioenergy alternative.</p></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"12013 - 12026"},"PeriodicalIF":5.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive method to detect nitazene analogues and xylazine in wastewater.","authors":"Emma L Keller, Brock Peake, Bradley S Simpson, Jason M White, Cobus Gerber","doi":"10.1007/s11356-025-36425-0","DOIUrl":"https://doi.org/10.1007/s11356-025-36425-0","url":null,"abstract":"<p><p>A class of novel synthetic opioids, nitazenes, have infiltrated the illicit drug market worldwide. Their high potency leading to overdose and fatality is a public health concern. Xylazine is a non-opiate sedative typically used for veterinary applications. The drug has recently appeared as an adulterant in the informal drug market, particularly within opioid drugs such as fentanyl and heroin. Determining the extent of use of these drugs is challenging due to low levels consumed. Wastewater analysis has been applied to monitor novel psychoactive substance use at a population level. This study presents the validation of a sensitive analytical method for the detection and quantification of trace levels of nitazenes and xylazine in wastewater. A solid phase extraction method was employed, yielding a concentration factor of 1000-fold. The method was applied to wastewater samples collected in Australia. Five different nitazenes were found near the limit of detection and quantitation levels, with detection frequencies ranging from 3 to 6% of all samples analysed. Xylazine was detected at a higher detection frequency (26% of all samples analysed). The method presented in this study could be used as an early warning system to track the use of xylazine and nitazenes internationally.</p>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative laccase-based hollow packed-bed reactor for continuous treatment of hospital wastewater","authors":"Komla Alokpa,&nbsp;Linson Lonappan,&nbsp;Hubert Cabana","doi":"10.1007/s11356-025-36395-3","DOIUrl":"10.1007/s11356-025-36395-3","url":null,"abstract":"<div><p>This study reports on laccase-mediated removal of trace organic compounds (TrOCs) from real hospital wastewater (HWW) in a packed-bed reactor (PBR). The reactor column consisted of a catalytic bed of amino-functionalized mesoporous silica microspheres attached to a hollow polyethylene packing on which a <i>Trametes hirsuta</i> laccase was immobilized. This bed material had the advantage of significantly limiting pressure drop, which is one of the major drawbacks of PBRs operating in continuous mode. The PBR was fed with HWW, previously filtered through a 0.45-µm PTFE filter. The HWW was used either unspiked or spiked at 1 µg L⁻¹ with acetaminophen, ibuprofen, naproxen, ketoprofen, mefenamic acid, indomethacin, and carbamazepine. A kinetic model combining the substrate conversion (1st-order kinetic) and the biocatalyst inactivation (1st-order kinetic) was developed and implemented, using acetaminophen as a model phenolic compound. After validation, the model showed good fit with experimental data and robustness regarding extended time operation with real HWW under uncontrolled conditions (pH, unbuffered media, ambient temperature). After 6 h of contact time, more than 95% of acetaminophen and mefenamic acid were removed in the PBR. In addition, toxicity tests showed that the laccase-based treatment resulted in a reduction in toxicity to <i>Daphnia magna</i>. The treated HWW did not significantly affect the mobility of <i>Daphnia magna</i>, unlike untreated HWW.</p></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"12027 - 12048"},"PeriodicalIF":5.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns and implications of plastic accumulation in mangrove ecosystems and sandy beaches in Western and Central regions of Ghana, West Africa","authors":"Geslaine Rafaela Lemos Gonçalves,&nbsp;Curtis Grey,&nbsp;Albert Koomson,&nbsp;Joseph Aggrey-Fynn,&nbsp;Benjamin Kofi Nyarko,&nbsp;Bhavani Emma Narayanaswamy","doi":"10.1007/s11356-025-36359-7","DOIUrl":"10.1007/s11356-025-36359-7","url":null,"abstract":"<div><p>Plastic pollution has become increasingly apparent in sandy beach zones and aquatic environments, creating more than just visual pollution. Impacts are observed in many environmental and social levels, including the fishing communities that depend on the coastal environment for their livelihoods. Plastic pollution was assessed on the sandy beaches and mangroves of Ghana’s Western and Central regions. The study’s objective was to determine the composition, abundance and sources of plastic litter at four different sites during the wet and dry seasons. Samples were collected from within 50 cm² quadrats placed randomly along four transects at each site. Plastic litter was classified according to the OSPAR guide. A total of 1895 plastic litter items with a combined weight of ~ 3000 g, representing 30 plastic categories, were collected. The average number and weight of plastic litter items were 19.73 ± 31.37 number of plastics per 50 cm² and 32.59 ± 45.47 g per 50 cm². The minimum and maximum plastic litter items were 0 to 159/50 cm². The highest amount of plastic litter was found in Ghana’s Central region. The total plastic litter weight is the variable that present statistical difference between the wet and dry season period. Bags, bottles, and fragments were the most common plastic items found, with 70% of the plastic litter being land-based, with the most frequent polymer types found in this study being polyethylene (~ 54%) and polypropylene (~ 20%). Mangrove regions act as sinks, specifically trapping plastic bags, contrary to the sandy beach areas, which mainly comprise plastic bottles that accumulate in these regions. Regions that have numerous communities, or are urbanised centres, tend to have higher levels or plastic litter. West Africa generally has poor waste management, absence of safe drinking water, and high levels of single-use plastics which are some of the main reasons for increased levels of plastic litter specifically in Ghana. Urgent actions are needed to prevent, mitigate and control plastic pollution in Ghana and the wider region.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"11996 - 12012"},"PeriodicalIF":5.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11356-025-36359-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fine extraction of multi-crop planting area based on deep learning with Sentinel- 2 time-series data","authors":"Jingmin Jiang,&nbsp;Jiahua Zhang,&nbsp;Xue Wang,&nbsp;Shichao Zhang,&nbsp;Delong Kong,&nbsp;Xiaopeng Wang,&nbsp;Shawkat Ali,&nbsp;Hidayat Ullah","doi":"10.1007/s11356-025-36405-4","DOIUrl":"10.1007/s11356-025-36405-4","url":null,"abstract":"<div><p>Accurate and timely access to the spatial distribution of crops is crucial for sustainable agricultural development and food security. However, extracting multi-crop areas based on high-resolution time-series data and deep learning still faces challenges. Therefore, this study aims to provide an effective model for multi-crop classification using high-resolution remote sensing time-series data. We designed two deep learning models based on convolutional neural network-long short-term memory (CNN-LSTM) and bidirectional long short-term memory (Bi-LSTM). The monthly synthetic time series of the normalized difference vegetation index (NDVI) from Sentinel-2 data will be used as input features to extract the multi-crop planting area in Shandong province’s northwestern, southwestern, and eastern regions. The results showed that deep learning models achieved higher accuracy compared to the random forest (RF) and extreme gradient boosting (XGBoost) models, with CNN-LSTM achieving the highest overall accuracy of 96.48%. At the county level, the coefficients of determination (<i>R</i>²) for the CNN-LSTM model were 0.91 for wheat, 0.88 for maize, and 0.73 for spring cotton. This study demonstrates that the CNN-LSTM model combined with monthly synthetic time-series NDVI provides a feasible approach for accurately mapping high-resolution multi-crop planting areas and also contributes significantly to decision support and resource management in agricultural production. </p></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"11931 - 11949"},"PeriodicalIF":5.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transformation of the drug ibuprofen by Priestia megaterium: reversible glycosylation and generation of hydroxylated metabolites","authors":"Tjorven Hinzke,&nbsp;Rabea Schlüter,&nbsp;Annett Mikolasch,&nbsp;Daniela Zühlke,&nbsp;Patrick Müller,&nbsp;Robert Kleditz,&nbsp;Katharina Riedel,&nbsp;Michael Lalk,&nbsp;Dörte Becher,&nbsp;Halah Sheikhany,&nbsp;Frieder Schauer","doi":"10.1007/s11356-025-36393-5","DOIUrl":"10.1007/s11356-025-36393-5","url":null,"abstract":"<div><p>As one of the most-consumed drugs worldwide, ibuprofen (IBU) reaches the environment in considerable amounts as environmental pollutant, necessitating studies of its biotransformation as potential removal mechanism. Here, we screened bacteria with known capabilities to degrade aromatic environmental pollutants, belonging to the genera <i>Bacillus</i>, <i>Priestia</i> (formerly also <i>Bacillus</i>), <i>Paenibacillus</i>, <i>Mycobacterium</i>, and <i>Cupriavidus</i>, for their ability to transform ibuprofen. We identified seven transformation products, namely 2-hydroxyibuprofen, carboxyibuprofen, ibuprofen pyranoside, 2-hydroxyibuprofen pyranoside, 4-carboxy-α-methylbenzene-acetic acid, 1-[4-(2-hydroxy-2-methylpropyl)phenyl]ethanone, and 2-hydroxyibuprofenmethyl ester. Based on our screening results, we focused on ibuprofen biotransformation by <i>Priestia megaterium</i> SBUG 518, to identify structures of transformation products, and to shed light on the drug’s impact on bacterial physiology. Biotransformation reactions by <i>P. megaterium</i> SBUG 518 involved (A) the hydroxylation of the isobutyl side chain at two positions, and (B) conjugate formation via esterification with a sugar molecule of the carboxylic group of ibuprofen and an ibuprofen hydroxylation product. Glycosylation seems to be a detoxification process, since the ibuprofen conjugate (ibuprofen pyranoside) was considerably less toxic than the parent compound to <i>P. megaterium</i> SBUG 518. Based on proteome profile changes and inhibition assays, cytochrome P450 systems appear to be central for ibuprofen transformation in <i>P. megaterium</i> SBUG 518. The toxic effect of ibuprofen appears to be caused by interference of the drug with different physiological pathways, especially sporulation.</p></div>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":"32 19","pages":"11981 - 11995"},"PeriodicalIF":5.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11356-025-36393-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}