Endocrinologia Y Nutricion最新文献

{"title":"Adenocarcinoma de tipo glándula salivar y adenoma paratiroideo intratiroideos en paciente con bocio multinodular","authors":"Sara Gómez Rodríguez , Guadalupe Guijarro de Armas , Naiara Modroño Móstoles , Carmen Pérez Blanco , Ana María Martín Hita","doi":"10.1016/j.endonu.2016.02.003","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.02.003","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 304-306"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.02.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Síndrome metabólico y enfermedad arterial periférica: 2 enfermedades relacionadas","authors":"Pilar Ángeles Oriol Torón ,&nbsp;Teresa Badía Farré ,&nbsp;Amparo Romaguera Lliso ,&nbsp;Jovita Roda Diestro","doi":"10.1016/j.endonu.2016.03.007","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.03.007","url":null,"abstract":"<div><h3>Aims</h3><p>To ascertain the prevalence of metabolic syndrome (MS) in patients with peripheral artery disease (PAD) at the Martorell primary care (PC) center. To analyze the differences in comorbidities and cardiovascular risk factors between patients with PAD with and without MS.</p></div><div><h3>Methods</h3><p>A cross-sectional, descriptive study on patients diagnosed with PAD according to computerized clinical records of the Martorell PC center. Variables collected included age, sex, high blood pressure (HBP), dyslipidemia (DLP), diabetes (DM), smoking, obesity, cardiovascular disease (CVD), erectile dysfunction (ED), renal failure (RF), and oligoalbuminuria. An analysis comparing patients with and without MS was performed.</p></div><div><h3>Results</h3><p>There were 131 patients diagnosed with PAD, 104 (79%) of whom were male. Sixty-three (48.1%) also had MS. Patients with both PAD and MS had, as compared to those with PAD only, a higher prevalence of HBP (87.3 vs. 60.3%, <em>P</em>: 0.001), DLP (77.8 vs. 60.3%, <em>P</em>: 0.03), DM (69.8 vs. 30.9%, <em>P</em>&lt;.001), obesity (25.4 vs. 10.3%, <em>P</em>: 0.03), CVD (42.9 vs. 19.1%); <em>P</em>: 0.004), ED (81.3 vs. 54.3%, <em>P</em>: 0.02), and RF (40.3 vs. 17.9%, <em>P</em>: 0.006).</p></div><div><h3>Conclusion</h3><p>Patients with both PAD and MS had a higher prevalence of HBP, DLP, DM, and obesity. They also had more cardiovascular events and were significantly associated with pathological conditions highly relevant for cardiovascular prognosis such as erectile dysfunction and chronic kidney disease.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 258-264"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacto y características diferenciales de la población de origen no caucásico en los ingresos por inicio de diabetes durante el periodo 2003-2010","authors":"Patricia San José,&nbsp;Mireia Guerrero,&nbsp;Isabel García-Martín,&nbsp;Jordi Caballero,&nbsp;Manuel Pérez-Maraver.","doi":"10.1016/j.endonu.2016.01.007","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.01.007","url":null,"abstract":"<div><h3>Aims</h3><p>To assess the prevalence of non-Caucasian patients in hospital admissions for onset of symptomatic diabetes mellitus during the 2003-2010 period, and to analyze the characteristics differentiating them from the Caucasian population at diagnosis and 2 years later.</p></div><div><h3>Material and methods</h3><p>A retrospective, observational study. Inclusion criteria: Patients aged 18-40 years admitted for de novo symptomatic diabetes from January 2003 to October 2010. Prevalence of patients of non-Caucasian origin was analyzed, and clinical, biochemical, immunological, and beta-cell function of both populations were compared at diagnosis and 2 years later.</p></div><div><h3>Results</h3><p>Nineteen percent of patients admitted to hospital for de novo symptomatic diabetes were non-Caucasian, with a progressive increase in recent years. Non-Caucasian patients had milder decompensation (3.0% had ketoacidosis, as compared to 15.2% in the Caucasian group, <em>P</em>&lt;.05), lower presence of autoimmunity (27.2 vs. 73.1%, <em>P</em>&lt;.01) and higher stimulated C-peptide levels (0.70<!--> <!-->±<!--> <!-->0.56 vs. 0.42<!--> <!-->±<!--> <!-->0.39 nmol/l, <em>P</em>&lt;.05), mainly because of the subgroup with negative autoimmunity (0.82 vs. 0.25). Two years after diagnosis, less non-Caucasian patients were on intensified treatment (39.1 vs. 93.8%).</p></div><div><h3>Conclusions</h3><p>Non-Caucasian patients had a lower prevalence of autoimmunity, better beta-cell function at diagnosis, particularly due to the subgroup with negative autoimmunity, and less need for intensive treatment 2 years after diagnosis, features which are more characteristic of type 2 diabetes mellitus.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 285-290"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.01.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encefalopatía hiperamoniémica tras cistectomía radical y derivación urinaria. Tratamiento nutricional","authors":"Miriam Moriana ,&nbsp;Juncal Martinez-Ibañez ,&nbsp;Miguel Civera ,&nbsp;José Francisco Martínez-Valls ,&nbsp;Juan Francisco Ascaso","doi":"10.1016/j.endonu.2016.03.006","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.03.006","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 306-308"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72056411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encefalitis límbica autoinmune en una niña con diabetes tipo 1. Hallazgos clínicos y evolución","authors":"M.ª Carmen Temboury Molina ,&nbsp;M.ª Luisa Ruiz-Falco Rojas ,&nbsp;Isabel Palmi Cortés ,&nbsp;Raquel Villamor Martín","doi":"10.1016/j.endonu.2016.03.004","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.03.004","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 308-310"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72056412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of frailty in older patients with diabetes mellitus: An overview","authors":"Amelia Cobo ,&nbsp;Luis A. Vázquez ,&nbsp;Jesús Reviriego ,&nbsp;Leocadio Rodríguez-Mañas","doi":"10.1016/j.endonu.2016.01.004","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.01.004","url":null,"abstract":"<div><p>Diabetes and frailty are two conditions that frequently occur concurrently and are increasingly prevalent in the older patient. We review the concept, epidemiology and consequences of frailty, and the implications of the presence of frailty in the management of diabetes. Frailty is associated with decreased quality of life, a risk of falls, new or increased disability, hospitalization, and increased mortality. All of these factors affect the management of diabetes in older patients. It is important to rule out frailty in all diabetic patients aged &gt;70 years; if frailty is suspected, a comprehensive and multidisciplinary medical and functional assessment of the patient should be conducted to develop an individualized treatment plan. This plan should include nutritional measures, physical activity, and education on self-care and diabetes; drugs should not be used without a clear indication. Antihyperglycemic drugs that may cause excessive weight loss and/or are associated with a high risk of hypoglycemia should be avoided.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 291-303"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibición de la proproteína convertasa subtilisina/kexina tipo 9 en el tratamiento de la hipercolesterolemia","authors":"Juan F. Ascaso","doi":"10.1016/j.endonu.2016.02.002","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.02.002","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 255-257"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"El Registro Molecular de Adenomas Hipofisarios (REMAH): una apuesta de futuro de la Endocrinología española por la medicina individualizada y la investigación traslacional","authors":"Raúl M. Luque ,&nbsp;Alejandro Ibáñez-Costa ,&nbsp;Laura Sánchez-Tejada ,&nbsp;Esther Rivero-Cortés ,&nbsp;Mercedes Robledo ,&nbsp;Ainara Madrazo-Atutxa ,&nbsp;Mireia Mora ,&nbsp;Clara V. Álvarez ,&nbsp;Tomás Lucas-Morante ,&nbsp;Cristina Álvarez-Escolá ,&nbsp;Carmen Fajardo ,&nbsp;Luis Castaño ,&nbsp;Sonia Gaztambide ,&nbsp;Eva Venegas-Moreno ,&nbsp;Alfonso Soto-Moreno ,&nbsp;María Ángeles Gálvez ,&nbsp;Javier Salvador ,&nbsp;Elena Valassi ,&nbsp;Susan M. Webb ,&nbsp;Antonio Picó ,&nbsp;Justo P. Castaño","doi":"10.1016/j.endonu.2016.03.001","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.03.001","url":null,"abstract":"<div><p>Pituitary adenomas are uncommon, difficult to diagnose tumors whose heterogeneity and low incidence complicate large-scale studies. The Molecular Registry of Pituitary Adenomas (REMAH) was promoted by the Andalusian Society of Endocrinology and Nutrition (SAEN) in 2008 as a cooperative clinical-basic multicenter strategy aimed at improving diagnosis and treatment of pituitary adenomas by combining clinical, pathological, and molecular information. In 2010, the Spanish Society of Endocrinology and Nutrition (SEEN) extended this project to national level and established 6 nodes with common protocols and methods for sample and clinical data collection, molecular analysis, and data recording in a common registry (<span>www.remahnacional.com</span><svg><path></path></svg>). The registry combines clinical data with molecular phenotyping of the resected pituitary adenoma using quantitative real-time PCR of expression of 26 genes: Pituitary hormones (GH-PRL-LH-FSH-PRL-ACTH-CGA), receptors (somatostatin, dopamine, GHRH, GnRH, CRH, arginine-vasopressin, ghrelin), other markers (Ki67, PTTG1), and control genes. Until 2015, molecular information has been collected from 704 adenomas, out of 1179 patients registered. This strategy allows for comparative and relational analysis between the molecular profile of the different types of adenoma and the clinical phenotype of patients, which may provide a better understanding of the condition and potentially help in treatment selection. The REMAH is therefore a unique multicenter, interdisciplinary network founded on a shared database that provides a far-reaching translational approach for management of pituitary adenomas, and paves the way for the conduct of combined clinical-basic innovative studies on large patient samples.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 274-284"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fe de errores de «Recomendaciones clínicas para la práctica del deporte en pacientes con diabetes mellitus (Guía RECORD). Grupo de Trabajo de Diabetes Mellitus de la Sociedad Española de Endocrinología y Nutrición (SEEN)»","authors":"Manuel Gargallo-Fernández ,&nbsp;Javier Escalada San Martín ,&nbsp;Fernando Gómez-Peralta ,&nbsp;Pedro Rozas Moreno ,&nbsp;Amparo Marco Martínez ,&nbsp;Marta Botella-Serrano ,&nbsp;Cristina Tejera Pérez ,&nbsp;Judith López Fernández ,&nbsp;en representación del Grupo de Trabajo de Diabetes Mellitus de la Sociedad Española de Endocrinología y Nutrición (SEEN)","doi":"10.1016/j.endonu.2016.03.002","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.03.002","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 314-315"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efecto de las terapias incretínicas comparadas con pioglitazona y gliclazida en la esteatosis hepática no alcohólica de los pacientes diabéticos no controlados solo con metformina: estudio observacional piloto","authors":"Eduardo García Díaz ,&nbsp;Danila Guagnozzi ,&nbsp;Verónica Gutiérrez ,&nbsp;Carmen Mendoza ,&nbsp;Cristina Maza ,&nbsp;Yulene Larrañaga ,&nbsp;Dolores Perdomo ,&nbsp;Teresa Godoy ,&nbsp;Ghalli Taleb","doi":"10.1016/j.endonu.2016.01.006","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.01.006","url":null,"abstract":"<div><h3>Aim</h3><p>To compare the effect of different hypoglycemic drugs on laboratory and ultrasonographic markers of non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes not controlled on metformin alone.</p></div><div><h3>Methods</h3><p>Prospective study of diabetic patients treated with metformin in combination with gliclazide, pioglitazone, sitagliptin, exenatide, or liraglutide. NAFLD was assessed by abdominal ultrasound and NAFLD fibrosis score was calculated at baseline and 6 months.</p></div><div><h3>Results</h3><p>Fifty-eight patients completed 6 months of follow-up: 15 received gliclazide, 13 pioglitazone, 15 sitagliptin, 7 exenatide, and 8 liraglutide. NAFLD affected 57.8% of patients at baseline, and its ultrasonographic course varied depending on changes in weight (<em>P</em> <!-->=<!--> <!-->.009) and waist circumference (<em>P</em> <!-->=<!--> <!-->.012). The proportions of patients who experienced ultrasonographic improvement in the different treatment groups were: 33.3% with gliclazide, 37.5% with pioglitazone, 45.5% with sitagliptin, 80% with exenatide, and 33% with liraglutide (<em>P</em> <!-->=<!--> <!-->.28).</p></div><div><h3>Conclusions</h3><p>Qualitative ultrasonographic NAFLD improvement in diabetic patients treated with metformin in combination with other hypoglycemic drugs is associated to change over time in weight and waist circumference. Long-term clinical trials are needed to assess whether incretin therapies result in better liver outcomes than other hypoglycemic therapies.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 5","pages":"Pages 194-201"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.01.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72066174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}