发布求助
文献互助 智能选刊 最新文献

Endocrinologia Y Nutricion最新文献

筛选
英文 中文
Study of the pathogenesis and treatment of diabetes mellitus through animal models 通过动物模型研究糖尿病的发病机制及治疗方法
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-05-28 DOI: 10.1016/j.endonu.2016.03.011
Yeray Brito-Casillas , Carlos Melián , Ana María Wägner
{"title":"Study of the pathogenesis and treatment of diabetes mellitus through animal models","authors":"Yeray Brito-Casillas ,&nbsp;Carlos Melián ,&nbsp;Ana María Wägner","doi":"10.1016/j.endonu.2016.03.011","DOIUrl":"10.1016/j.endonu.2016.03.011","url":null,"abstract":"<div><p>Most research in diabetes mellitus (DM) has been conducted in animals, and their replacement is currently a chimera. As compared to when they started to be used by modern science in the 17th century, a very high number of animal models of diabetes is now available, and they provide new insights into almost every aspect of diabetes. Approaches combining human, in vitro, and animal studies are probably the best strategy to improve our understanding of the underlying mechanisms of diabetes, and the choice of the best model to achieve such objective is crucial. Traditionally classified based on pathogenesis as spontaneous or induced models, each has its own advantages and disadvantages. The most common animal models of diabetes are described, and in addition to non-obese diabetic mice, biobreeding diabetes-prone (BB-DP) rats, streptozotocin-induced models, or high-fat diet-induced diabetic C57Bl/6J mice, new valuable models, such as dogs and cats with spontaneous diabetes, are described.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 345-353"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34430852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Ensayos clínicos de resultados de enfermedad cardiovascular en diabetes 糖尿病心血管疾病临床试验结果
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-06-17 DOI: 10.1016/j.endonu.2016.04.001
Manuel Muñoz Torres , Araceli Muñoz Garach
{"title":"Ensayos clínicos de resultados de enfermedad cardiovascular en diabetes","authors":"Manuel Muñoz Torres ,&nbsp;Araceli Muñoz Garach","doi":"10.1016/j.endonu.2016.04.001","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.04.001","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 317-319"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72062109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Medullary thyroid carcinoma as manifestation of the loss of heterozygosity in a patient with MEN1 甲状腺髓样癌是MEN1患者杂合性缺失的表现
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-05-27 DOI: 10.1016/j.endonu.2016.03.005
Gloria Beatriz Aranda Velazquez , Mireia Mora Porta , Daniel Martínez , Josep Oriola , Irene Halperin Rabinovich
{"title":"Medullary thyroid carcinoma as manifestation of the loss of heterozygosity in a patient with MEN1","authors":"Gloria Beatriz Aranda Velazquez ,&nbsp;Mireia Mora Porta ,&nbsp;Daniel Martínez ,&nbsp;Josep Oriola ,&nbsp;Irene Halperin Rabinovich","doi":"10.1016/j.endonu.2016.03.005","DOIUrl":"10.1016/j.endonu.2016.03.005","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 371-373"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34439615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Thyroid dysfunction in the era of precision medicine 精准医疗时代的甲状腺功能障碍
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-06-03 DOI: 10.1016/j.endonu.2016.04.009
Juan C. Galofré , Juan J. Díez , David S. Cooper
{"title":"Thyroid dysfunction in the era of precision medicine","authors":"Juan C. Galofré ,&nbsp;Juan J. Díez ,&nbsp;David S. Cooper","doi":"10.1016/j.endonu.2016.04.009","DOIUrl":"10.1016/j.endonu.2016.04.009","url":null,"abstract":"<div><p>The launching of the <em>Precision Medicine Initiative</em> by the President of the United States in January 2015 was an invitation for all healthcare professionals to review their practice. This call should stimulate thyroidologists working in different areas (from basic research or epidemiology to the frontline of the clinical arena or to those designing public health programs) to be aware of this new outlook. The aim of the initiative is to eradicate imprecision in estimating the probability of a correct diagnosis, to be as sure as possible of the most effective treatment, and to maximize the chances of a successful outcome. This paper summarizes some of the current challenges faced by endocrinologists in the field of thyroid dysfunction, and illustrates how precision medicine may improve diagnosis and therapy in the future.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 354-363"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.04.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34551701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Comentarios sobre «Hipercarotinemia tras cirugía bariátrica» 关于“减肥手术后高颈动脉粥样硬化”的评论
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-06-23 DOI: 10.1016/j.endonu.2016.05.007
Patricia Soblechero Martin, Fernando Granado Lorencio, Encarnación Donoso Navarro, M. Ramona de los Ángeles Silvestre Mardomingo
{"title":"Comentarios sobre «Hipercarotinemia tras cirugía bariátrica»","authors":"Patricia Soblechero Martin,&nbsp;Fernando Granado Lorencio,&nbsp;Encarnación Donoso Navarro,&nbsp;M. Ramona de los Ángeles Silvestre Mardomingo","doi":"10.1016/j.endonu.2016.05.007","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.05.007","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 374-375"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.05.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72062114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucocorticoid resistance syndrome caused by two novel mutations in the NR3C1 gene 由NR3C1基因的两个新突变引起的糖皮质激素抵抗综合征
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-05-17 DOI: 10.1016/j.endonu.2016.03.010
Teresa Velayos , Gema Grau , Itxaso Rica, Gustavo Pérez-Nanclares, Sonia Gaztambide
{"title":"Glucocorticoid resistance syndrome caused by two novel mutations in the NR3C1 gene","authors":"Teresa Velayos ,&nbsp;Gema Grau ,&nbsp;Itxaso Rica,&nbsp;Gustavo Pérez-Nanclares,&nbsp;Sonia Gaztambide","doi":"10.1016/j.endonu.2016.03.010","DOIUrl":"10.1016/j.endonu.2016.03.010","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 369-371"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34508974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Opciones reproductivas en pacientes con osteogénesis imperfecta. A propósito de 2 casos de la misma familia con una nueva mutación en COL1A1 成骨不全患者的生殖选择。针对同一家族中COL1A1新突变的2例
Endocrinologia Y Nutricion Pub Date : 2016-08-01 Epub Date: 2016-05-10 DOI: 10.1016/j.endonu.2016.04.002
Isabel Pavón de Paz , Belén Gil Fournier , Cristina Navea Aguilera , Sara Gómez Rodríguez , María Soraya Ramiro León
{"title":"Opciones reproductivas en pacientes con osteogénesis imperfecta. A propósito de 2 casos de la misma familia con una nueva mutación en COL1A1","authors":"Isabel Pavón de Paz ,&nbsp;Belén Gil Fournier ,&nbsp;Cristina Navea Aguilera ,&nbsp;Sara Gómez Rodríguez ,&nbsp;María Soraya Ramiro León","doi":"10.1016/j.endonu.2016.04.002","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.04.002","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 7","pages":"Pages 367-369"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72062112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cribado de la enfermedad tiroidea en el embarazo 妊娠期甲状腺疾病的筛查
Endocrinologia Y Nutricion Pub Date : 2016-06-01 Epub Date: 2016-01-18 DOI: 10.1016/j.endonu.2015.12.002
Luis Valdivielso Cañas
{"title":"Cribado de la enfermedad tiroidea en el embarazo","authors":"Luis Valdivielso Cañas","doi":"10.1016/j.endonu.2015.12.002","DOIUrl":"https://doi.org/10.1016/j.endonu.2015.12.002","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 311-312"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2015.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72056413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Percentiles de circunferencia de cintura en escolares de Bogotá (Colombia): Estudio FUPRECOL 哥伦比亚波哥大学童腰围百分比：Fuprecol研究
Endocrinologia Y Nutricion Pub Date : 2016-06-01 Epub Date: 2016-04-03 DOI: 10.1016/j.endonu.2016.01.008
Juan Carlos Caicedo-Álvarez , Jorge Enrique Correa-Bautista , Emilio González-Jiménez , Jacqueline Schmidt-RioValle , Robinson Ramírez-Vélez
{"title":"Percentiles de circunferencia de cintura en escolares de Bogotá (Colombia): Estudio FUPRECOL","authors":"Juan Carlos Caicedo-Álvarez ,&nbsp;Jorge Enrique Correa-Bautista ,&nbsp;Emilio González-Jiménez ,&nbsp;Jacqueline Schmidt-RioValle ,&nbsp;Robinson Ramírez-Vélez","doi":"10.1016/j.endonu.2016.01.008","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.01.008","url":null,"abstract":"<div><h3>Objective</h3><p>This study was intended to establish the percentile distribution of waist circumference in schoolchildren from Bogota, Colombia, participating in the FUPRECOL Study.</p></div><div><h3>Methods</h3><p>A cross-sectional study conducted in 3,005 children and 2,916 adolescents aged 9 to 17.9 years. Height, weight, waist circumference, hip circumference, and self-assessed sexual maturity status were recorded. Percentiles (3<sup>rd</sup>, 10<sup>th</sup>, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, 90<sup>th</sup>, and 97<sup>th</sup>) and smoothed sex- and age-specific curves were calculated, and the waist circumference values found were compared to international references from other ethnic populations.</p></div><div><h3>Results</h3><p>Fifty-seven percent of the overall population (n<!--> <!-->=<!--> <!-->5,921) were females (mean age, 12.7<!--> <!-->±<!--> <!-->2.3 years). In most age groups, waist circumference was greater in boys as compared to girls. The increase between the 50<sup>th</sup> and 97<sup>th</sup> percentiles by age was 15.7<!--> <!-->cm in boys aged 9 to 9.9 years and 16.0<!--> <!-->cm in girls aged 11-11.9 years. Comparison of our study results, by age group and sex, to international references showed that our 50<sup>th</sup> percentile was lower than reported in Peru and the UK except for studies in India, Venezuela (Merida), US, and Spain was higher.</p></div><div><h3>Conclusions</h3><p>Age- and sex-specific percentiles of waist circumference obtained from children and adolescents from Bogota, Colombia, are reported. They may be used as a reference both for nutritional assessment and for predicting cardiovascular risks at early ages.</p></div>","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 265-273"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.01.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72069510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Carta respuesta: cribado de la enfermedad tiroidea en el embarazo 信件答复：妊娠甲状腺疾病筛查
Endocrinologia Y Nutricion Pub Date : 2016-06-01 Epub Date: 2016-04-15 DOI: 10.1016/j.endonu.2016.03.003
Sergio Donnay Candil
{"title":"Carta respuesta: cribado de la enfermedad tiroidea en el embarazo","authors":"Sergio Donnay Candil","doi":"10.1016/j.endonu.2016.03.003","DOIUrl":"https://doi.org/10.1016/j.endonu.2016.03.003","url":null,"abstract":"","PeriodicalId":54323,"journal":{"name":"Endocrinologia Y Nutricion","volume":"63 6","pages":"Pages 312-313"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.endonu.2016.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72056414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书