{"title":"Gaps and solutions for large scale production of cultured meat: a review on last findings","authors":"Da Young Lee, Sun Jin Hur","doi":"10.1016/j.cofs.2024.101243","DOIUrl":"10.1016/j.cofs.2024.101243","url":null,"abstract":"<div><div>Despite initial expectations, the full-scale industrialization of cultured meat has not yet been realized owing to technical difficulties yet to be resolved. Therefore, this review discusses the delayed industrialization of cultured meat and strategies to overcome this delay. The identified challenges include a low cell growth rate, consistency, muscle satellite cell differentiation, completely defined medium components and their roles in myogenesis, effective fetal bovine serum replacement, and the inconsistencies of muscle formation <em>in vitro</em>. Another reason for the delay is the inherent dependence on animal-sourced cell culture products, which raise ethical concerns and are not considered safe for consumption. Technologies related to efficient cultured meat production remain imperative. This study also emphasizes the importance of using cell lines or immortalized cells and efficient culturing strategies to achieve the full industrialization of cultured meat.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101243"},"PeriodicalIF":8.9,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142744989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myrsini N Kakagianni , Enda Cummins , Vasilis P Valdramidis
{"title":"Quantitative tools in food safety and risk assessment to address technological innovations and climate change","authors":"Myrsini N Kakagianni , Enda Cummins , Vasilis P Valdramidis","doi":"10.1016/j.cofs.2024.101237","DOIUrl":"10.1016/j.cofs.2024.101237","url":null,"abstract":"<div><div>In a globalized food market with an extensive agro-industrial sector, establishing and maintaining food safety is a significant challenge. Despite extensive research and advanced technological tools for monitoring and controlling food pathogens and toxins, outbreaks and toxification incidents persist. The complexity of food production, varied raw material sources, and differing governance levels highlight the need for a comprehensive approach to food safety. Climate change exacerbates the situation, as elevated temperatures may increase the likelihood of food pathogens or toxins reaching harmful levels. Understanding the multiple factors that undermine food safety, alongside advancements in monitoring and control strategies, including molecular (e.g. next-generation sequencing) and analytical (spectroscopic or chromatographic) technologies, can help address these challenges. Implementing a uniform comprehensive food safety platform can establish effective processes for estimating and ensuring food safety, helping to keep foodborne hazards at bay.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101237"},"PeriodicalIF":8.9,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sumin Cho , Seok Yeong Jung , Hyunmin Eun , Sang Yup Lee
{"title":"Precision fermentation for producing food ingredients","authors":"Sumin Cho , Seok Yeong Jung , Hyunmin Eun , Sang Yup Lee","doi":"10.1016/j.cofs.2024.101242","DOIUrl":"10.1016/j.cofs.2024.101242","url":null,"abstract":"<div><div>Fermentation has been crucial in human history, evolving in meaning with advances in biotechnology. Advancements in synthetic biology and metabolic engineering have led to the emergence of precision fermentation, which involves using metabolically engineered microbes to produce functional ingredients from simple carbon sources under precisely controlled conditions. These technologies have the potential to develop sustainable platforms for producing food ingredients, which could help address food crisis issues. This review discusses how systems metabolic engineering can be applied to precision fermentation-based production of food ingredients in microbial hosts, with a particular focus on the production of flavoring and coloring agents. Additionally, the development of optimal downstream processing techniques for each product category is also examined.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101242"},"PeriodicalIF":8.9,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142744990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beatriz Quintanilla-Casas , Berta Torres-Cobos , Rasmus Bro , Francesc Guardiola , Stefania Vichi , Alba Tres
{"title":"The volatile metabolome — gas chromatography–mass spectrometry approaches in the context of food fraud","authors":"Beatriz Quintanilla-Casas , Berta Torres-Cobos , Rasmus Bro , Francesc Guardiola , Stefania Vichi , Alba Tres","doi":"10.1016/j.cofs.2024.101235","DOIUrl":"10.1016/j.cofs.2024.101235","url":null,"abstract":"<div><div>This work discusses food authentication tools based on the volatile metabolome assessed by gas chromatography-mass spectrometry (GC-MS). Volatile organic compounds (VOCs) serve as markers for food flavor and aroma, and in some cases, they hold potential for food authentication. On top of this, advanced data analysis approaches enhance analytical data extraction and understanding. Untargeted methods provide comprehensive authenticity insights, surpassing traditional targeted approaches, and automated processing improves robustness and reduces user dependency. Chemometric tools, particularly classification methods, are extensively used for authentication based on both GC-MS fingerprinting and untargeted profiling of VOCs. Despite challenges in transferability, untargeted methods perform well in authentication models, making them valuable for internal quality control and official control guidance for fraud detection. This work highlights the need for further research to establish untargeted authentication tools as official methods in the near future.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101235"},"PeriodicalIF":8.9,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142744991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Next-generation probiotics delivery: innovations and applications of single-cell encapsulation","authors":"Aijun Xie, Mengge Gao, Haishun Du, Xuejun Pan","doi":"10.1016/j.cofs.2024.101234","DOIUrl":"10.1016/j.cofs.2024.101234","url":null,"abstract":"<div><div>Probiotics have demonstrated significant health benefits, particularly in gastrointestinal health, but their viability is often compromised by environmental stress during production, storage, and transit through the digestive system. Traditional encapsulation techniques, such as spray drying and freeze-drying, have limitations in protecting probiotics. Recently, single-cell encapsulation has emerged as a promising strategy, providing individualized protection to each probiotic cell. This technique enhances stability, ensures targeted release in the gastrointestinal tract, and improves overall therapeutic effectiveness. This review explores the latest advancements in single-cell encapsulation, focusing on innovative wall materials, such as amino acids, Eudragit, and polyphenol complexes. Additionally, it discusses emerging applications in areas beyond gut health, including cancer therapy and bioimaging. Despite its potential, challenges remain in scaling production and ensuring efficacy in human trials. Addressing these issues could pave the way for next-generation probiotics with enhanced therapeutic capabilities.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101234"},"PeriodicalIF":8.9,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lidong Pang , Runze Li , Zhen Huang , Xinyan Yang , Yujun Jiang
{"title":"Milk protein–polyphenol–saccharide ternary complexes: Improved health and functional properties","authors":"Lidong Pang , Runze Li , Zhen Huang , Xinyan Yang , Yujun Jiang","doi":"10.1016/j.cofs.2024.101239","DOIUrl":"10.1016/j.cofs.2024.101239","url":null,"abstract":"<div><div>Milk protein–polyphenol–saccharide (MPPS) ternary complexes are receiving increasing attention for their superior health and functional properties. This paper systematically reviews recent advancements in MPPS for improving health and functional properties and discusses the remaining challenges and future trends. Research has proven that MPPS ternary complexes are a promising raw food material. However, the formation mechanism involved in MPPS and the mechanism through which the preparation conditions, the source of raw materials, and the order of preparation affect MPPS still need to be studied in-depth. Additionally, covalent preparation methods, casein-based MPPS, increased health and functional properties, and safety will require extensive in-depth research.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101239"},"PeriodicalIF":8.9,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ziyan Hua , Shu Liu , Guang Yang , Xiaoyue Hou , Yaowei Fang
{"title":"Next-generation probiotics: innovations in safety assessments","authors":"Ziyan Hua , Shu Liu , Guang Yang , Xiaoyue Hou , Yaowei Fang","doi":"10.1016/j.cofs.2024.101238","DOIUrl":"10.1016/j.cofs.2024.101238","url":null,"abstract":"<div><div>The human gut microbiota is integral to health and disease, fostering the development of next-generation probiotics (NGPs) tailored for specific health conditions. This review addresses the safety assessments and development of NGPs, highlighting recent biotechnological advances that enable the customization of NGPs for specific health conditions. It examines the methodologies for <em>in vitro</em> and <em>in vivo</em> animal model assessments focusing on potential toxicity. Additionally, we explore the integration of multi-omics, synthetic biology, and advanced computational technologies, including artificial intelligence and machine learning, to enhance the precision and safety of NGPs. Incorporating NGPs into food matrices represents an effective approach to delivering these probiotics and enhancing the health benefits of food products. This review underscores the necessity of adopting comprehensive safety assessments to navigate the complexities of NGP development effectively.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101238"},"PeriodicalIF":8.9,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in smartphone-based biosensors for food testing","authors":"Shoucheng Qin, Xueyan Sun, Xihong Zhao","doi":"10.1016/j.cofs.2024.101236","DOIUrl":"10.1016/j.cofs.2024.101236","url":null,"abstract":"<div><div>Food is an essential part of human life, and with economic growth, the focus has shifted from quantity to quality and safety. Rapid food testing, which involves identifying suspicious samples from a large number of food samples quickly, is crucial. A promising approach is to integrate current food analysis techniques with smartphone-based detection systems. This review summarizes recent developments in smartphone-based biosensors for portable food detection, presenting both single-mode and dual-mode biosensors on smartphones, as well as common materials used for optical sensing biosensors. The advancements in smartphone-based biosensors are driven by artificial intelligence technology. In this review, we discuss not only the technical principles and applications but also the challenges and future perspectives for smartphone-based biosensors.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"61 ","pages":"Article 101236"},"PeriodicalIF":8.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristina Hidalgo , Santiago Ruiz-Moyano , Manuel J Serradilla , Ana I Galván , Alicia Rodríguez
{"title":"Elicitors: impact on the fungal pathogenicity and colonization in fruits","authors":"Cristina Hidalgo , Santiago Ruiz-Moyano , Manuel J Serradilla , Ana I Galván , Alicia Rodríguez","doi":"10.1016/j.cofs.2024.101233","DOIUrl":"10.1016/j.cofs.2024.101233","url":null,"abstract":"<div><div>Fruit rotting caused by filamentous fungus is a serious global issue affecting both economics and food safety. Therefore, effective strategies to combat the occurrence of filamentous fungi in fruit are required. Elicitors, for example, have been demonstrated to improve the physicochemical, nutritional, and functional quality of fruits, making them desirable for controlling fungal colonization and mycotoxin production. In this review, we will first explore the problem of fungal colonization in fruits, as well as the primary control measures. Second, research into the effects of the most important elicitors on fruit quality has been conducted. Finally, the most current studies on elicitors’ influence on fungal growth, as well as their primary routes of action, are discussed. We can conclude that while there is evidence that elicitors can reduce fungal pathogenicity and mycotoxin formation, more <em>in vivo</em> research is needed to assess their efficacy in various fruit types and conditions.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"60 ","pages":"Article 101233"},"PeriodicalIF":8.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}