Gaozhong Yang, Zihao Qiu, Yue Zhang, Haipeng Lv, Paul A Kilmartin
{"title":"Molecular remodeling of waste-derived polyphenols: engineering tea and grape by-products into high-value functional molecules","authors":"Gaozhong Yang, Zihao Qiu, Yue Zhang, Haipeng Lv, Paul A Kilmartin","doi":"10.1016/j.cofs.2026.101438","DOIUrl":"10.1016/j.cofs.2026.101438","url":null,"abstract":"<div><div>The tea and wine industries generate millions of tonnes of polyphenol-rich residues annually, yet conventional valorization relies on solvent extraction of native molecules, inheriting instability and poor bioavailability. We argue that molecular remodeling — applying enzymatic, microbial, chemical, and supramolecular tools to redesign waste-derived polyphenols — is a more productive frame. We organize the literature through a Liberation–Remodeling–Validation framework linking three pathways: oxidative upcycling of catechins to benzotropolone dimers and anthocyanins to polymeric pigments; structural derivatization through acylation, pyranoanthocyanin formation, and depolymerization; and intermolecular assembly via copigmentation and protein–pigment complexes. Natural deep eutectic solvents emerge as green media to liberate, solubilize, and stabilize remodeled products. We contend that molecular remodeling, rather than extraction, unlocks the functional potential of tea and grape by-products, shifting priority from purified-substrate proofs-of-concept to real waste matrices. <em>In vivo</em> toxicology, dose–response validation, and regulatory frameworks for these chemically distinct entities remain largely undeveloped and must be addressed before industrial translation.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"70 ","pages":"Article 101438"},"PeriodicalIF":8.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148642402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maricel Vidal, Marcela Fresno, David Pezoa, Boris Parra, Dácil Rivera
{"title":"From fragmentation to integration: the case of multidrug-resistant Salmonella and the need for One Health-based governance in Chile","authors":"Maricel Vidal, Marcela Fresno, David Pezoa, Boris Parra, Dácil Rivera","doi":"10.1016/j.cofs.2026.101437","DOIUrl":"10.1016/j.cofs.2026.101437","url":null,"abstract":"<div><div>Foodborne pathogens such as <em>Salmonella</em> exemplify the challenges of modern food safety governance, where biological adaptability intersects with fragmented surveillance across human, animal, and environmental sectors. Owing to its ubiquity, antigenic diversity, and public health impact, <em>Salmonella</em> remains a priority target for integrated surveillance under a One Health framework. Accordingly, this review analyzes the structure, strengths, and limitations of the current surveillance landscape in Chile within a broader Latin American context, with particular emphasis on multidrug-resistant (MDR) lineages. Available evidence indicates the emergence and persistence of MDR <em>Salmonella</em>, particularly <em>S.</em> Infantis, across interconnected reservoirs, including poultry production systems, surface waters, food products, and human infections. Although advances in whole-genome sequencing (WGS) and national surveillance initiatives have improved strain characterization and reporting capacity, integration across genomic, epidemiological, and environmental datasets remains incomplete, thereby limiting interoperability and timely response. In this context, Chile represents a relevant case study, demonstrating both the feasibility and the challenges of transitioning toward integrated One Health surveillance. While coordinated regulatory frameworks and pilot initiatives have established a foundation for cross-sectoral monitoring, fragmentation in governance, data systems, and environmental coverage continues to hinder full implementation. Consequently, surveillance efforts often remain compartmentalized, reducing their capacity to support rapid risk assessment and coordinated interventions. Overall, this review highlights the need to move from parallel surveillance efforts toward interoperable, real-time surveillance systems supported by harmonized methodologies, integrated genomic analyses, and shared governance structures. Ultimately, strengthening these components will be essential to improve early detection, source attribution, and coordinated control of MDR <em>Salmonella</em> in complex food systems, while advancing One Health-based governance in Chile and comparable settings.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"70 ","pages":"Article 101437"},"PeriodicalIF":8.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148642404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are short and ultra-short chain polyfluorinated substances environmental or food contaminants? Reframing exposure pathways across the food system","authors":"Pier Paolo Becchi , Leilei Zhang , Luigi Lucini","doi":"10.1016/j.cofs.2026.101413","DOIUrl":"10.1016/j.cofs.2026.101413","url":null,"abstract":"<div><div>Food contamination by per- and polyfluoroalkyl substances (PFAS) is a growing concern because of their persistence and potential health risks. The phase-out of long-chain (LC) PFAS has accelerated the use of short-chain (SC) and ultra-short-chain (USC) alternatives, which are generally more polar and water-soluble, thus mobile, promoting dispersion through soils and waters and linking environmental reservoirs to food production and processing. Toxicological evidence indicates that SC/USC-PFAS hazards cannot be overlooked. From a food-system perspective, rather than viewing ‘environmental’ versus ‘food contamination’ as separate domains, primary agricultural production and food-contact materials (FCM) act as interconnected sources of dietary exposure, yet source attribution of SC/USC-PFAS is particularly challenging given their precursor-rich occurrence in FCM and incomplete analytical coverage. Improved analytics (hybrid extraction and high-resolution mass spectrometry) enhance the detection of SC/USC-PFAS in complex foods, but comprehensive monitoring remains challenging, underscoring the need for robust methods to support regulation.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"69 ","pages":"Article 101413"},"PeriodicalIF":9.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Staphylococcus aureus and S. argenteus in food systems: Toxigenicity, resistance, and surveillance at the animal-human-environmental interface","authors":"Alexandra Fetsch, Sophia Johler","doi":"10.1016/j.cofs.2026.101415","DOIUrl":"10.1016/j.cofs.2026.101415","url":null,"abstract":"<div><div>Staphylococci remain a challenge for food safety and public health, driven by toxin-mediated disease, antimicrobial resistance, and interconnected food systems. This review critically examined <em>Staphylococcus aureus</em> and <em>S. argenteus</em> as a foodborne hazard, integrating evidence on staphylococcal food poisoning, methicillin-resistant <em>S. aureus</em> (MRSA), and recent advances in detection and surveillance. It critically appraises trends in outbreak investigations—particularly the shift from enterotoxin detection to genomic screening—and evaluates preventive strategies. We highlight limitations of genome-based approaches in predicting toxin presence and caution against widespread nasal decolonisation of asymptomatic food handlers with mupirocin, given high recolonisation rates and resistance risks. The review further discusses livestock-associated MRSA as a One Health challenge spanning production, processing, and public health. Finally, we examine advances in predictive microbiology and AI-enabled tools that offer new opportunities for integrated surveillance, risk assessment, and targeted control of staphylococcal hazards in food systems.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"69 ","pages":"Article 101415"},"PeriodicalIF":9.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Laage Kragh, Lisbeth Truelstrup Hansen, Paw Dalgaard
{"title":"The solution to Listeria monocytogenes problems in the food industry is product stabilization in combination with cleaning and disinfection","authors":"Martin Laage Kragh, Lisbeth Truelstrup Hansen, Paw Dalgaard","doi":"10.1016/j.cofs.2026.101414","DOIUrl":"10.1016/j.cofs.2026.101414","url":null,"abstract":"<div><div>Listeriosis cases continue to rise due to <em>Listeria monocytogenes</em> contaminated ready-to-eat foods. Recent studies show that <em>L. monocytogenes</em> persistence in food processing environments is poorly explained by biocide tolerance but strongly linked to biofilm, equipment design, and repeated introduction from raw materials. Daily cleaning and sanitation practices can reset levels but cannot be relied on to eliminate the bacterium. Producers can in some cases control <em>L. monocytogenes</em> through in-package inactivation, e.g., by heat. However, for many products, efficient <em>L. monocytogenes</em> management can be achieved by adjusting preservation methods and/or shelf-life. Design of suitable approaches to stabilize products against listerial growth is now facilitated by validated predictive models and software. We suggest a voluntary label to communicate the safety of stabilized products to consumers. To decrease future outbreaks, implicated products should be characterized and evaluated using validated predictive models to adjust declared shelf-life and/or preservation to avoid unacceptable <em>L. monocytogenes</em> growth.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"69 ","pages":"Article 101414"},"PeriodicalIF":9.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wilson JF Lemos Junior , M Victoria Moreno-Arribas
{"title":"Micro- and nanoplastics, metagenomics, and food systems: toward an integrated perspective","authors":"Wilson JF Lemos Junior , M Victoria Moreno-Arribas","doi":"10.1016/j.cofs.2026.101379","DOIUrl":"10.1016/j.cofs.2026.101379","url":null,"abstract":"<div><div>Micro- and nanoplastics (MNPs) are increasingly embedded across food systems, from soils and aquaculture to food-contact materials and processed products, raising concerns about their impact on the gut microbiome. Ingestion is now a recognized exposure route, with particles found in foods and in human stools, blood, and other tissues. Their small size, heterogeneous chemistry, and capacity to carry additives and pollutants enable close interactions with gut epithelia and resident microbes. Multi-omics studies show that MNPs alter community structure, enrich stress-tolerant taxa, disrupt functional pathways, and can act as vectors for antibiotic resistance genes and mobile elements. Gut consortia also harbor enzymes capable of degrading synthetic polymers, though the physiological implications remain unclear. Food matrices, diet, and co-exposure to additives further modulate MNP fate and bioavailability. This perspective integrates metagenomic evidence and highlights how multi-omics, Artificial Intelligence (AI), and advanced models can inform One Health–aligned risk assessment and guide safer, more sustainable food systems.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"68 ","pages":"Article 101379"},"PeriodicalIF":9.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146175338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hoda Taheri Sedeh , Jens A Hammerl , Stefan Hertwig , Oliver K Schlüter
{"title":"Bacteriophage-assisted nonthermal processing of foods: challenges and innovative concepts to inactivate microbial pathogens","authors":"Hoda Taheri Sedeh , Jens A Hammerl , Stefan Hertwig , Oliver K Schlüter","doi":"10.1016/j.cofs.2026.101380","DOIUrl":"10.1016/j.cofs.2026.101380","url":null,"abstract":"<div><div>Bacteriophage-assisted nonthermal food processing (BANTFP) is a potential biocontrol strategy for reducing food-borne pathogens while preserving product quality. When used simultaneously or sequentially with novel nonthermal food processing (NTFP) technologies, phages can contribute to the reduction of the microbes (typically 1–3 Δlog, but up to 5–8 Δlog in optimized multihurdle systems). However, the current evidence is fragmented and strongly biased toward high-pressure studies, whereas data for the use of pulsed electric fields, ultrasound, and cold atmospheric plasma remain limited. Key challenges include phage stability under processing conditions, their interactions with complex food matrices, and the risk of resistance development of the target bacteria. Further research is required to identify optimal treatment sequences, quantify true synergistic effects, and evaluate performance in realistic food environments. Such efforts are essential to refine phage–NTFP combinations, ensuring their efficiency and regulatory acceptance at an industrial scale and contributing to safe, innovative, and sustainable food processing systems.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"68 ","pages":"Article 101380"},"PeriodicalIF":9.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147386578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphing foods: recent progress and future innovations","authors":"Sushil Koirala , Ruoyao Li , Sangeeta Prakash , Azharul Karim , Bhesh Bhandari","doi":"10.1016/j.cofs.2026.101388","DOIUrl":"10.1016/j.cofs.2026.101388","url":null,"abstract":"<div><div>In everyday life, foods often change shape upon heating through processes such as shrinking, swelling, or puffing, but these responses are usually naturally occurring and uncontrolled, reflecting the interplay between structure, moisture transport and thermal effects. Morphing foods apply these principles intentionally, using designed material heterogeneity and surface geometric modifications to achieve predictable and controllable shape transformations during processing. In this review, we critically examine recent progress in stamping, 4D food printing, surface cutting and bilayer lamination as fabrication strategies for controlled morphing in real food systems. This work emphasises the underlying mechanism, constraints and relative industrial readiness of different morphing approaches. Together, these perspectives position morphing foods as an emerging direction in food materials design with implications for functionality, sustainability and consumer experience.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"68 ","pages":"Article 101388"},"PeriodicalIF":9.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147386528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sensory analysis in the pharmaceutical and nutraceutical industries: its role in the development and testing of new products","authors":"Pia I Hedelund , Kevin Kantono , Bilge Balci","doi":"10.1016/j.cofs.2026.101387","DOIUrl":"10.1016/j.cofs.2026.101387","url":null,"abstract":"<div><div>Sensory analysis has been traditionally associated with the food and beverage industry and has recently become increasingly integral to developing and evaluating pharmaceutical and nutraceutical products. This paper explores the application of sensory evaluation techniques in nutra and pharma industries, highlighting their role, limitations, and challenges that it presents in product formulation and consumer palatability. Recent advancements in sensory methodologies, including instrumental techniques like electronic tongues and noses, as well as consumer-driven approaches, are discussed. Significant challenges remain, particularly the lack of international standards, regulatory alignment, and guidance tailored to the unique constraints of products containing actives, both active pharmaceutical ingredients (API), and active ingredients (AcI) used in nutraceutical products. Critical issues, such as the cognitive impact of long breaks between assessments, limitations of once-daily testing due to active ingredients and excipients, and their effect on data validity, have yet to be adequately addressed or resolved. We recommend addressing the need for internationally standardized methodologies, alignment with regulatory bodies, knowledge sharing, and advanced solutions to tackle these gaps, enabling sensory science to provide valid and robust insight to support patient-centered nutra and pharma product development fully.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"68 ","pages":"Article 101387"},"PeriodicalIF":9.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147386579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in the generation mechanism, detection methods, and reduction strategies of biogenic amines in aquatic products: a review","authors":"Lina Zhong , Mantong Zhao , Guanghua Xia , Dayong Zhou , Zhongyuan Liu","doi":"10.1016/j.cofs.2026.101378","DOIUrl":"10.1016/j.cofs.2026.101378","url":null,"abstract":"<div><div>Aquatic products are prone to spoilage, along with the generation of biogenic amines (BAs) during storage and transportation, which may affect their quality and safety. BAs are primarily generated after the decarboxylation of aquatic products’ proteins and catalyzed by endogenous enzymes derived from spoilage organisms. The different structures of BAs made their generation mechanisms extremely complex. Excessive consumption of BAs can trigger harmful physiological reactions, thereby exerting potential health risks to consumers. Therefore, the current work reviewed the generation mechanisms of BAs from aquatic products, as well as the conventional and innovative detection methods and multidimensional reduction strategies. Moreover, the advantages and limitations of these methods were also discussed, through which some valuable insights regarding the preservation of aquatic product quality and consumer acceptance could be obtained.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"67 ","pages":"Article 101378"},"PeriodicalIF":9.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}