Ultrasonography最新文献

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Does transperineal ultrasound predict the risk of perineal trauma in women with term pregnancy? A prospective observational study. 经会阴超声能否预测足月妊娠妇女会阴创伤的风险?一项前瞻性观察研究。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2024-01-01 Epub Date: 2023-09-19 DOI: 10.14366/usg.23045
Serena Xodo, Giulia Trombetta, Caterina Morassutto, Giovanni Baccarini, Lisa Celante, Lorenza Driul, Ambrogio P Londero
{"title":"Does transperineal ultrasound predict the risk of perineal trauma in women with term pregnancy? A prospective observational study.","authors":"Serena Xodo, Giulia Trombetta, Caterina Morassutto, Giovanni Baccarini, Lisa Celante, Lorenza Driul, Ambrogio P Londero","doi":"10.14366/usg.23045","DOIUrl":"10.14366/usg.23045","url":null,"abstract":"<p><strong>Purpose: </strong>This study was conducted to evaluate the prevalence of perineal trauma during childbirth and to assess the correlations of the pelvic floor dimensions and fetal head station with obstetric trauma in a prospectively recruited cohort of women.</p><p><strong>Methods: </strong>The study included women with a gestational age of at least 37 weeks, who were carrying a single fetus in a cephalic presentation. Transperineal ultrasound (TPU) was performed prior to the onset of labor or labor induction. The purpose was to measure the anteroposterior diameter (APD) of the levator ani muscle (LAM) and the angle of progression, at both rest and maximum Valsalva maneuver. The head-perineum distance was assessed only at rest.</p><p><strong>Results: </strong>A total of 296 women were included. Of the 253 women who delivered vaginally, 19% (48/253) experienced no perineal trauma, 18.2% (46/253) received an episiotomy during childbirth, 34.4% (87/253) sustained a first-degree laceration, 25.3% (64/253) had a second-degree laceration, and 3.2% had a third- or fourth-degree laceration (8/253). Women with episiotomy had a significantly shorter median APD under Valsalva than women without perineal trauma. Furthermore, women with LAM coactivation (identified by a negative difference between the APD at Valsalva and the APD at rest) were approximately three times more likely to undergo an operative vaginal delivery and over five times more likely to sustain a third- or fourth-degree tear during childbirth than women who exhibited normal relaxation of the LAM during the Valsalva maneuver.</p><p><strong>Conclusion: </strong>TPU may predict the risk of perineal trauma in women with term pregnancy during childbirth.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10766888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasonography: celebrating 10 years of progress and opening a new chapter in 2024. 超声波造影术:庆祝十年进步,2024 年开启新篇章。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.14366/usg.23230
Jung-Eun Cheon
{"title":"Ultrasonography: celebrating 10 years of progress and opening a new chapter in 2024.","authors":"Jung-Eun Cheon","doi":"10.14366/usg.23230","DOIUrl":"10.14366/usg.23230","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10766886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139099230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of contrast-enhanced ultrasonography in microwave ablation treatment of symptomatic focal uterine adenomyosis. 对比增强超声造影在微波消融治疗症状性局灶性子宫腺肌症中的价值。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-11-07 DOI: 10.14366/usg.23145
Xiao-Long Li, Jia-Xin Li, Song-Yuan Yu, Pei-Li Fan, Yun-Jie Jin, Er-Jiao Xu, Sai-Nan Guan, Er-Ya Deng, Qiu-Yan Li, Zheng-Biao Ji, Jiu-Ling Qi, Hui-Xiong Xu
{"title":"Value of contrast-enhanced ultrasonography in microwave ablation treatment of symptomatic focal uterine adenomyosis.","authors":"Xiao-Long Li, Jia-Xin Li, Song-Yuan Yu, Pei-Li Fan, Yun-Jie Jin, Er-Jiao Xu, Sai-Nan Guan, Er-Ya Deng, Qiu-Yan Li, Zheng-Biao Ji, Jiu-Ling Qi, Hui-Xiong Xu","doi":"10.14366/usg.23145","DOIUrl":"https://doi.org/10.14366/usg.23145","url":null,"abstract":"This study evaluated the value of contrast-enhanced ultrasonography (CEUS) in the ultrasound-guided microwave ablation (MWA) treatment of symptomatic focal uterine adenomyosis.","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138743647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of a deep learning artificial intelligence model for the diagnosis of pediatric ileocolic intussusception with grayscale ultrasonography. 利用灰度超声波检查诊断小儿回结肠肠套叠的深度学习人工智能模型的可行性。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-10-10 DOI: 10.14366/usg.23153
Se Woo Kim, Jung-Eun Cheon, Young Hun Choi, Jae-Yeon Hwang, Su-Mi Shin, Yeon Jin Cho, Seunghyun Lee, Seul Bi Lee
{"title":"Feasibility of a deep learning artificial intelligence model for the diagnosis of pediatric ileocolic intussusception with grayscale ultrasonography.","authors":"Se Woo Kim, Jung-Eun Cheon, Young Hun Choi, Jae-Yeon Hwang, Su-Mi Shin, Yeon Jin Cho, Seunghyun Lee, Seul Bi Lee","doi":"10.14366/usg.23153","DOIUrl":"https://doi.org/10.14366/usg.23153","url":null,"abstract":"This study explored the feasibility of utilizing a deep learning artificial intelligence (AI) model to detect ileocolic intussusception on grayscale ultrasound images.","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138743771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overcoming the limitations of screening mammography in Japan and Korea: a paradigm shift to personalized breast cancer screening based on ultrasonography. 克服日本和韩国筛查乳房X光检查的局限性:基于超声的个性化乳腺癌症筛查的范式转变。
IF 2.4 3区 医学
Ultrasonography Pub Date : 2023-10-01 Epub Date: 2023-07-26 DOI: 10.14366/usg.23047
Takayoshi Uematsu, Ayumi Izumori, Woo Kyung Moon
{"title":"Overcoming the limitations of screening mammography in Japan and Korea: a paradigm shift to personalized breast cancer screening based on ultrasonography.","authors":"Takayoshi Uematsu, Ayumi Izumori, Woo Kyung Moon","doi":"10.14366/usg.23047","DOIUrl":"10.14366/usg.23047","url":null,"abstract":"<p><p>Screening mammography programs have been implemented in numerous Western countries with the aim of reducing breast cancer mortality. However, despite over 20 years of population-based screening mammography, the mortality rates in Japan and Korea continue to rise. This may be due to the fact that screening mammography is not as effective for Japanese and Korean women, who often have dense breasts. This density decreases the sensitivity of mammography due to a masking effect. Therefore, the early detection of small invasive cancers requires more than just mammography, particularly for women in their 40s. This review discusses the limitations and challenges of screening mammography, as well as the keys to successful population-based breast cancer screening in Japan and Korea. This includes a focus on breast ultrasonography techniques, which are based on histopathologic anatomical knowledge, and personalized screening strategies that are based on risk assessments measured by glandular tissue components.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/03/b9/usg-23047.PMC10555688.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10212599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sonazoid-enhanced ultrasonography for noninvasive imaging diagnosis of hepatocellular carcinoma: special emphasis on the 2022 KLCA-NCC guideline. Sonazoid增强超声对肝细胞癌的无创成像诊断:特别强调2022年KLCA-NCC指南。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-10-01 Epub Date: 2023-06-15 DOI: 10.14366/usg.23051
Hyo-Jin Kang, Jeong Min Lee, Se Woo Kim
{"title":"Sonazoid-enhanced ultrasonography for noninvasive imaging diagnosis of hepatocellular carcinoma: special emphasis on the 2022 KLCA-NCC guideline.","authors":"Hyo-Jin Kang,&nbsp;Jeong Min Lee,&nbsp;Se Woo Kim","doi":"10.14366/usg.23051","DOIUrl":"10.14366/usg.23051","url":null,"abstract":"<p><p>Contrast-enhanced ultrasonography (CEUS) is a noninvasive imaging modality used to diagnose hepatocellular carcinoma (HCC) based on specific imaging features, without the need for pathologic confirmation. Two types of ultrasound contrast agents are commercially available: pure intravascular agents (such as SonoVue) and Kupffer agents (such as Sonazoid). Major guidelines recognize CEUS as a reliable imaging method for HCC diagnosis, although they differ depending on the contrast agents used. The Korean Liver Cancer Association-National Cancer Center guideline includes CEUS with either SonoVue or Sonazoid as a second-line diagnostic technique. However, Sonazoid-enhanced ultrasound is associated with several unresolved issues. This review provides a comparative overview of these contrast agents regarding pharmacokinetic features, examination protocols, diagnostic criteria for HCC, and potential applications in the HCC diagnostic algorithm.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cd/69/usg-23051.PMC10555687.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10122294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Value of Doppler ultrasonography in predicting clinical outcomes for patients with acute cellular rejection after liver transplantation. 多普勒超声在预测肝移植术后急性细胞排斥反应患者临床转归中的价值。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-10-01 Epub Date: 2023-08-06 DOI: 10.14366/usg.23112
Ji Young Choi, Kyoung Won Kim, Jong Keon Jang, Sang Hyun Choi, Heon-Ju Kwon, Young-In Yoon, Gi-Won Song, Sung-Gyu Lee
{"title":"Value of Doppler ultrasonography in predicting clinical outcomes for patients with acute cellular rejection after liver transplantation.","authors":"Ji Young Choi,&nbsp;Kyoung Won Kim,&nbsp;Jong Keon Jang,&nbsp;Sang Hyun Choi,&nbsp;Heon-Ju Kwon,&nbsp;Young-In Yoon,&nbsp;Gi-Won Song,&nbsp;Sung-Gyu Lee","doi":"10.14366/usg.23112","DOIUrl":"10.14366/usg.23112","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the value of Doppler ultrasonography in predicting clinical outcomes after antirejection treatment for patients with acute cellular rejection (ACR) following liver transplantation (LT).</p><p><strong>Methods: </strong>This retrospective study included 84 patients who were pathologically diagnosed with ACR and received antirejection treatment within 90 days following LT. Two radiologists searched for abnormal Doppler parameters at ACR diagnosis and within 7 days after antirejection treatment initiation, including portal blood velocity (PBV) <20 cm/s, hepatic artery resistive index <0.5, and a monophasic hepatic vein flow pattern. Interval PBV changes were also evaluated. The frequencies of abnormal Doppler parameters and PBV changes were compared by treatment outcome.</p><p><strong>Results: </strong>The frequency of abnormal PBV in the early post-treatment phase (PBVearly post-treatment) was significantly higher among poor responders (50.0% [10/20]) than among good responders (7.8% [5/64]) (P<0.001). The sensitivity, specificity, and accuracy of abnormal PBVearly post-treatment as a predictor of poor response to antirejection treatment were 50.0% (10/20), 92.2% (59/64), and 82.1% (69/84), respectively. A decrease (>10%) from the PBV at event (PBVevent) to PBVearly post-treatment was significantly more common among poor responders (50.0% [10/20]) than among good responders (20.3% [13/64]) (P=0.019). The sensitivity, specificity, and accuracy of this PBV decrease in predicting poor treatment response were 50.0% (10/20), 79.7% (51/64), and 72.6% (61/84), respectively.</p><p><strong>Conclusion: </strong>Abnormal PBVearly post-treatment and a decrease between PBVevent and PBVearly post-treatment were significantly associated with poor treatment response in patients with ACR after LT. Consequently, Doppler ultrasonography may be useful for predicting clinical outcomes in these patients.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/35/67/usg-23112.PMC10555689.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10226803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of fusion imaging for the evaluation of ultrasound quality in hepatocellular carcinoma surveillance. 融合成像在肝细胞癌监测超声质量评估中的应用。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-10-01 Epub Date: 2023-08-15 DOI: 10.14366/usg.23106
Yeun-Yoon Kim, Seo-Bum Cho, Jae Seung Lee, Hye Won Lee, Jin-Young Choi, Seung Up Kim
{"title":"Utility of fusion imaging for the evaluation of ultrasound quality in hepatocellular carcinoma surveillance.","authors":"Yeun-Yoon Kim,&nbsp;Seo-Bum Cho,&nbsp;Jae Seung Lee,&nbsp;Hye Won Lee,&nbsp;Jin-Young Choi,&nbsp;Seung Up Kim","doi":"10.14366/usg.23106","DOIUrl":"10.14366/usg.23106","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the quality of surveillance ultrasound (US) for hepatocellular carcinoma (HCC) utilizing fusion imaging.</p><p><strong>Methods: </strong>This research involved a secondary analysis of a prospectively recruited cohort. Under institutional review board approval, participants referred for surveillance US who had undergone liver computed tomography (CT) or magnetic resonance imaging (MRI) within the past year were screened between August 2022 and January 2023. After patient consent was obtained, the US visualization score in the Liver Imaging Reporting and Data System was assessed with fusion imaging at the time of examination. This score was compared to that of conventional US using the extended McNemar test. Multivariable logistic regression analysis was used to identify factors independently associated with a US visualization score of B or C. Factors limiting visualization of focal lesions were recorded during fusion imaging.</p><p><strong>Results: </strong>Among the 105 participants (mean age, 59±11 years; 66 men), US visualization scores of B and C were assigned to 57 (54.3%) and 17 (16.2%) participants, respectively, by conventional US and 54 (51.4%) and 32 (30.5%) participants, respectively, by fusion imaging. The score distribution differed significantly between methods (P=0.010). Male sex was independently associated with US visualization scores of B or C (adjusted odds ratio, 3.73 [95% confidence interval, 1.30 to 10.76]; P=0.015). The most common reason (64.5%) for lesion nondetection was a limited sonic window.</p><p><strong>Conclusion: </strong>Conventional US may underestimate the limitations of the sonic window relative to real-time fusion imaging with pre-acquired CT or MRI in the surveillance of HCC.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/37/usg-23106.PMC10555691.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10362038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiparametric ultrasound for upper extremity dialysis access evaluation. 用于上肢透析通路评估的多参数超声。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-10-01 Epub Date: 2023-07-12 DOI: 10.14366/usg.23064
Vasileios Michas, Mehdi Taghipour, Angeliki Papachristodoulou, Maria Sidiropoulou, Sasan Partovi, Demosthenes Cokkinos, Vasileios Rafailidis, Sameer Gadani, Amanjit Gill, Hans Michell, Panos Prassopoulos
{"title":"Multiparametric ultrasound for upper extremity dialysis access evaluation.","authors":"Vasileios Michas,&nbsp;Mehdi Taghipour,&nbsp;Angeliki Papachristodoulou,&nbsp;Maria Sidiropoulou,&nbsp;Sasan Partovi,&nbsp;Demosthenes Cokkinos,&nbsp;Vasileios Rafailidis,&nbsp;Sameer Gadani,&nbsp;Amanjit Gill,&nbsp;Hans Michell,&nbsp;Panos Prassopoulos","doi":"10.14366/usg.23064","DOIUrl":"10.14366/usg.23064","url":null,"abstract":"<p><p>The evolution of ultrasound (US) techniques has greatly improved the evaluation of many parameters in dialysis vascular access, which is typically achieved through an arteriovenous fistula (AVF) or graft (AVG). These techniques include grayscale B-mode, color Doppler, power Doppler, spectral Doppler, non-Doppler US flow imaging techniques, contrast-enhanced US, and elastography. In conjunction with a patient's medical history and physical examination, US provides crucial information about the native vascular bed prior to the surgical creation of an arteriovenous anastomosis. It also tracks the maturation progress of the newly created AVF or AVG and aids in diagnosing potential complications of the vascular access. These complications include thrombosis, steal syndrome, aneurysms, pseudoaneurysms, hematomas, infection, ischemic neuropathy, exacerbation of preexisting congestive heart failure, and stenosis.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/05/89/usg-23064.PMC10555685.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10310831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative analysis using intraoperative contrast-enhanced ultrasound in adult-type diffuse gliomas with isocitrate dehydrogenase mutations: association between hemodynamics and molecular features. 术中超声造影定量分析伴有异柠檬酸脱氢酶突变的成人型弥漫性胶质瘤:血流动力学和分子特征之间的关系。
IF 3.1 3区 医学
Ultrasonography Pub Date : 2023-10-01 Epub Date: 2023-07-17 DOI: 10.14366/usg.23031
Xiandi Zhang, Zhifeng Shi, Yuanxin Xie, Yong Wang, Chao Shen, Zengxin Qi, Liqiong Zhang, Bojie Yang, Jinhua Yu, Hong Ding
{"title":"Quantitative analysis using intraoperative contrast-enhanced ultrasound in adult-type diffuse gliomas with isocitrate dehydrogenase mutations: association between hemodynamics and molecular features.","authors":"Xiandi Zhang,&nbsp;Zhifeng Shi,&nbsp;Yuanxin Xie,&nbsp;Yong Wang,&nbsp;Chao Shen,&nbsp;Zengxin Qi,&nbsp;Liqiong Zhang,&nbsp;Bojie Yang,&nbsp;Jinhua Yu,&nbsp;Hong Ding","doi":"10.14366/usg.23031","DOIUrl":"10.14366/usg.23031","url":null,"abstract":"<p><strong>Purpose: </strong>The relationship between contrast-enhanced ultrasound (CEUS) hemodynamics and the molecular biomarkers of adult-type diffuse gliomas, particularly isocitrate dehydrogenase (IDH), remains unclear. This study was conducted to provide a comprehensive description of the vascularization of adult-type diffuse gliomas using quantitative indicators. Additionally, it was designed to identify any variables with the potential to intraoperatively predict IDH mutation status.</p><p><strong>Methods: </strong>This prospective study enrolled patients with adult-type diffuse gliomas between November 2021 and September 2022. Intraoperative CEUS was performed, and CEUS videos were recorded for 90-second periods. Hemodynamic parameters, including the peak enhancement (PE) difference, were calculated based on the time-intensity curve of the region of interest. A differential analysis was performed on the CEUS parameters with respect to molecular biomarkers and grades. Receiver operating characteristic curves for various parameters were analyzed to evaluate the ability of those parameters to predict IDH mutation status.</p><p><strong>Results: </strong>Sixty patients with adult-type diffuse gliomas were evaluated. All hemodynamic parameters, apart from rising time, demonstrated significant differences between IDH-mutant and IDH-wildtype adult-type diffuse gliomas. The PE difference emerged as the optimal indicator for differentiating between IDH-wildtype and IDH-mutant gliomas, with an area under the curve of 0.958 (95% confidence interval, 0.406 to 0.785). Additionally, the hemodynamic parameters revealed significant differences across both grades and types of adult-type diffuse gliomas.</p><p><strong>Conclusion: </strong>Hemodynamic parameters can be used intraoperatively to effectively distinguish between IDHwildtype and IDH-mutant adult-type diffuse gliomas. Additionally, quantitative CEUS equips neurosurgeons with dynamic perfusion information for various types and grades of adult-type diffuse gliomas.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/08/55/usg-23031.PMC10555694.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10246582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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