Ultrasonography最新文献

{"title":"Comprehensive ultrasonographic evaluation of normal and fibrotic kidneys in a mouse model with an ultra-high-frequency transducer.","authors":"Myoung Seok Lee, Jeong Yeon Cho, Min Hoan Moon, Jeonghwan Lee, Jung Pyo Lee, Nayeon Shin, Wencheng Jin, Ara Cho","doi":"10.14366/usg.24024","DOIUrl":"10.14366/usg.24024","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to establish baseline morphological and functional data for normal mouse kidneys via a clinical 33 MHz ultra-high-frequency (UHF) transducer, compare the data with the findings from fibrotic mice, and assess correlations between ultrasonography (US) parameters and fibrosis-related markers.</p><p><strong>Methods: </strong>This retrospective study aggregated data from three separate experiments (obstructive nephropathy, diabetic nephropathy, and acute-to-chronic kidney injury models). Morphological parameters (kidney size, parenchymal thickness [PT]) and functional (shear-wave speed [SWS], stiffness, resistive index [RI], and microvascular imaging-derived vascular index [VI]) were assessed and compared between normal and fibrotic mouse kidneys. Semi-quantitative histopathologic scores were calculated and molecular markers (epithelial cadherin), Collagen 1A1 [Col1A1], transforming growth factor-β, and α-smooth muscle actin [α-SMA]) were evaluated using western blots. Correlations with US parameters were explored.</p><p><strong>Results: </strong>Clinical UHF US successfully imaged the kidneys of the experimental mice. A three-layer configuration was prevalent in the normal mouse kidney parenchyma (34/35) but was blurred in most fibrotic mouse kidneys (33/40). US parameters, including size (11.14 vs. 10.70 mm), PT (2.07 vs. 1.24 mm), RI (0.64 vs. 0.77), VI (22.55% vs. 11.47%, only for non-obstructive kidneys), SWS (1.67 vs. 2.06 m/s), and stiffness (8.23 vs. 12.92 kPa), showed significant differences between normal and fibrotic kidneys (P&lt;0.001). These parameters also demonstrated strong discriminative ability in receiver operating characteristic curve analysis (area under the curve, 0.76 to 0.95; P&lt;0.001). PT, VI, and RI were significantly correlated with histological fibrosis markers (ρ=-0.64 to -0.68 for PT and VI, ρ=0.71-0.76 for RI, P&lt;0.001). VI exhibited strong negative correlations with Col1A1 (ρ=-0.76, P=0.006) and α-SMA (ρ=-0.75, P=0.009).</p><p><strong>Conclusion: </strong>Clinical UHF US effectively distinguished normal and fibrotic mouse kidneys, indicating the potential of US parameters, notably VI, as noninvasive markers for tracking fibrosis initiation and progression in mouse kidney fibrosis models.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic value of transvaginal contrast-enhanced ultrasound for identifying benign and malignant endometrial lesions and assessing myometrial invasion.","authors":"Fang Guo, Yulin Yan, Chengsheng Huang, Xia Wang, Xing Wu, Yanli Xu, Tao Ying","doi":"10.14366/usg.24097","DOIUrl":"https://doi.org/10.14366/usg.24097","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141819677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential role of 2D-shear wave elastography including liver stiffness measurement and dispersion slope for management of chronic hepatitis B","authors":"S. Song, Y. Kim, Young Hwan Lee, Eun Young Cho","doi":"10.14366/usg.24091","DOIUrl":"https://doi.org/10.14366/usg.24091","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of heat insulation efficacy between 5% dextrose and 0.9% saline in vitro during radiofrequency ablation","authors":"Yanping Ma, Jinfen Wang, Tao Wu, Bowen Zheng, Tinghui Yin, Yufan Lian, Jie Ren","doi":"10.14366/usg.24073","DOIUrl":"https://doi.org/10.14366/usg.24073","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of SARS-COV-2 infection on Doppler ultrasound and placental findings of pregnant women: A systematic review and meta-analysis.","authors":"Lanying Chen, Tingting Yin, Danni Cai, Xiaomin Chen","doi":"10.14366/usg.24038","DOIUrl":"https://doi.org/10.14366/usg.24038","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141644799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"US features of normal parathyroid glands confirmed during thyroid surgery in adult patients","authors":"Seong Ju Kim, W. Paik, Jong Cheol Lee, Yong Jin Song, Kwanghyun Yoon, Byeong-Joo Noh, D. G. Na","doi":"10.14366/usg.24104","DOIUrl":"https://doi.org/10.14366/usg.24104","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative diagnosis of early acute compartment syndrome by 2D-SWE in a rabbit model.","authors":"Jun Zhang, Kunlong Duan, Junci Wei, Wanfu Zhang, Huihui Zhou, Lin Sang, Yuan Sun, Xue Gong, Hao Guan, Ming Yu","doi":"10.14366/usg.24067","DOIUrl":"https://doi.org/10.14366/usg.24067","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using the quality threshold to improve liver shear wave elasticity measurements in free-breathing pediatric patients","authors":"Jisoo Kim, Naohisa Kamiyama, Shunichiro Tanigawa, Haesung Yoon, Hyun Ji Lim, Mi-Jung Lee","doi":"10.14366/usg.24054","DOIUrl":"https://doi.org/10.14366/usg.24054","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141671018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic features of the skin and subcutis: correlations with the severity of breast cancer-related lymphedema.","authors":"Ji Youn Park, Jae Yong Jeon, Seungwoo Cha","doi":"10.14366/usg.24059","DOIUrl":"10.14366/usg.24059","url":null,"abstract":"<p><strong>Purpose: </strong>Assessing the severity of breast cancer-related lymphedema (BCRL) requires various clinical tools, yet no standardized methodology is available. Ultrasonography shows promise for diagnosing lymphedema and evaluating its severity. This study explored the clinical utility of ultrasonography in patients with BCRL.</p><p><strong>Methods: </strong>In this retrospective cross-sectional study, patients with unilateral BCRL were examined. The analyzed data included demographics, lymphedema location, International Society of Lymphology (ISL) stage, surgical history, treatment regimens, and arm circumference. Skin, subcutis, and muscle thicknesses were assessed ultrasonographically at predetermined sites, and the percentage of excess thickness was calculated. Multivariate logistic regression analysis was employed to identify associations between ultrasonographic measurements and advanced lymphedema (ISL 2 or 3). The Lymphedema Quality of Life arm questionnaire was used to evaluate patient-reported outcomes regarding lymphedema and their correlations with ultrasonographic findings.</p><p><strong>Results: </strong>Among 118 patients, 71 were classified as ISL 0-1 and 47 as ISL 2-3. Patients with advanced lymphedema were older, had higher nodal stages, underwent more axillary lymph node dissections, and had higher rates of dominant-arm lymphedema. Multivariate logistic regression revealed significant associations of greater skin thickness (adjusted odds ratio [OR], 4.634; 95% confidence interval [CI], 1.233 to 17.419), subcutis thickness (adjusted OR, 7.741; 95% CI, 1.649 to 36.347), and subcutis echogenicity (adjusted OR, 4.860; 95% CI, 1.517 to 15.566) with advanced lymphedema. Furthermore, greater skin thickness (P=0.016) and subcutis echogenicity (P=0.023) were correlated with appearance-related discomfort.</p><p><strong>Conclusion: </strong>Ultrasonographic measurements were significantly associated with advanced lymphedema in BCRL. Ultrasonography represents a valuable diagnostic and severity assessment tool for lymphedema.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of quantitative ultrasonography for hepatic steatosis in a health screening program: a prospective single-center study.","authors":"Jeung Hui Pyo, Soo Jin Cho, Sung Chul Choi, Jae Hwan Jee, Jeeyeong Yun, Jeong Ah Hwang, Goeun Park, Kyunga Kim, Wonseok Kang, Mira Kang, Young Hye Byun","doi":"10.14366/usg.24040","DOIUrl":"10.14366/usg.24040","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared the diagnostic performance of quantitative ultrasonography (QUS) with that of conventional ultrasonography (US) in assessing hepatic steatosis among individuals undergoing health screening using magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) as the reference standard.</p><p><strong>Methods: </strong>This single-center prospective study enrolled 427 participants who underwent abdominal MRI and US. Measurements included the attenuation coefficient in tissue attenuation imaging (TAI) and the scatter-distribution coefficient in tissue scatter-distribution imaging (TSI). The correlation between QUS and MRI-PDFF was evaluated. The diagnostic capabilities of QUS, conventional B-mode US, and their combined models for detecting hepatic fat content of ≥5% (MRI-PDFF ≥5%) and ≥10% (MRI-PDFF ≥10%) were compared by analyzing the areas under the receiver operating characteristic curves. Additionally, clinical risk factors influencing the diagnostic performance of QUS were identified using multivariate linear regression analyses.</p><p><strong>Results: </strong>TAI and TSI were strongly correlated with MRI-PDFF (r=0.759 and r=0.802, respectively; both P&lt;0.001) and demonstrated good diagnostic performance in detecting and grading hepatic steatosis. The combination of QUS and B-mode US resulted in the highest areas under the ROC curve (AUCs) (0.947 and 0.975 for detecting hepatic fat content of ≥5% and ≥10%, respectively; both P&lt;0.05), compared to TAI, TSI, or B-mode US alone (AUCs: 0.887, 0.910, 0.878 for ≥5% and 0.951, 0.922, 0.875 for ≥10%, respectively). The independent determinants of QUS included skinliver capsule distance (β=7.134), hepatic fibrosis (β=4.808), alanine aminotransferase (β=0.202), triglyceride levels (β=0.027), and diabetes mellitus (β=3.710).</p><p><strong>Conclusion: </strong>QUS is a useful and effective screening tool for detecting and grading hepatic steatosis during health checkups.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}