Pratique Neurologique - FMC最新文献

{"title":"Thérapies dans la méningite carcinomateuse du cancer du poumon, du sein et le mélanome : revue systématique de la littérature","authors":"H. Duprez,&nbsp;E. Vauleon,&nbsp;M. Curti,&nbsp;M. Swiderski,&nbsp;A. Monfilliette,&nbsp;L. Defebvre,&nbsp;A. Deniel","doi":"10.1016/j.praneu.2024.04.010","DOIUrl":"10.1016/j.praneu.2024.04.010","url":null,"abstract":"<div><h3>Introduction</h3><p>La méningite carcinomateuse est une complication rare dans la maladie cancéreuse, retrouvée le plus fréquemment chez des patients atteints de cancers du poumon, de cancer du sein, et de mélanome ; son pronostic est péjoratif. Sa prise en charge est un challenge thérapeutique, notamment en raison de la perméabilité partielle de la barrière hémato-encéphalique aux différentes thérapies utilisées en cancérologie. Notre objectif est de réaliser une revue systématique des thérapeutiques de la méningite carcinomateuse dans le cadre de ces 3 tumeurs primitives en prenant comme base initiale les recommandations de l’ESMO de 2017.</p></div><div><h3>Méthode</h3><p>Nous avons réalisé une revue systématique de la littérature sur PubMed et ClinicalTrial entre 2017 et août 2023 ayant permis de retrouver 116 articles inclus dans cette revue dont 19 essais prospectifs.</p></div><div><h3>Résultats</h3><p>Les principaux résultats des études thérapeutiques entre 2017 et 2023 ont été repris dans des tableaux synthétiques selon la tumeur primitive.</p></div><div><h3>Discussion</h3><p>La méningite carcinomateuse reste une pathologie incurable avec un pronostic sombre. L’ensemble des thérapeutiques disponibles actuellement, en dehors d’essais cliniques, ont une efficacité qui reste modeste, notamment en ce qui concerne les chimiothérapies intraveineuses et intrathécales. On retrouve cependant des pistes prometteuses avec les thérapies ciblées, les anticorps conjugués, l’immunothérapie et la protonthérapie. Devant l’essor des traitements oncologiques et l’amélioration de la survie de patients pour de nombreux cancers, l’inclusion plus systématique dans les essais cliniques de patients atteints de méningite carcinomateuse, souvent responsable d’un échappement thérapeutique, semble indispensable.</p></div><div><h3>Introduction</h3><p>Carcinomatous meningitis is a rare complication that occurs most often in patients with lung cancer, breast cancer, or melanoma, generally with poor prognosis. Management poses a therapeutic challenge, particularly due to the partial permeability of the blood-brain barrier to various cancer treatments. Our objective was to conduct a systematic review of therapies proposed for carcinomatous meningitis in the context of these three primary tumors, using the 2017 guidelines from the European Society for Medical Oncology (ESMO) as our initial foundation.</p></div><div><h3>Method</h3><p>We conducted a systematic literature review on PubMed and ClinicalTrial between 2017 and August 2023, which allowed us to identify 116 articles for this review, including 19 prospective trials.</p></div><div><h3>Results</h3><p>The primary findings from therapeutic studies conducted between 2017 and 2023 have been summarized in concise tables categorized by the primary tumor.</p></div><div><h3>Discussion</h3><p>Carcinomatous meningitis remains an incurable condition with a grim prognosis. The therapeutic approaches currently employed, ou","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages 71-92"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Condensé ou concentré de neurologie. À propos de Paolo Bartoloméo. Dernières nouvelles du cerveau Paris : éditions Flammarion, 2023","authors":"C. Thomas-Anterion","doi":"10.1016/j.praneu.2024.04.003","DOIUrl":"10.1016/j.praneu.2024.04.003","url":null,"abstract":"","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Page 141"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beau, bien, vrai… vrai, bien, beau. À propos de Jean-Pierre Changeux. Le beau et la splendeur du vrai Paris : éditions Albin Michel/éditions Odile Jacob , 2023","authors":"C. Thomas-Anterion","doi":"10.1016/j.praneu.2024.04.005","DOIUrl":"10.1016/j.praneu.2024.04.005","url":null,"abstract":"","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Page 142"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calcifications hippocampiques, une découverte pas forcément fortuite","authors":"B. Cretin ,&nbsp;G. Hautecloque-Raysz ,&nbsp;F. Sellal","doi":"10.1016/j.praneu.2024.03.002","DOIUrl":"10.1016/j.praneu.2024.03.002","url":null,"abstract":"","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages 122-123"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140405758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L’amnésie développementale : un syndrome souvent négligé","authors":"P.-Y. Jonin","doi":"10.1016/j.praneu.2024.03.001","DOIUrl":"10.1016/j.praneu.2024.03.001","url":null,"abstract":"<div><p>Nous présentons le cas d’un patient de 27 ans présentant un syndrome d’amnésie développementale sévère. Ce diagnostic est rarement évoqué devant une plainte mnésique chez les patients jeunes, et le plus souvent posé très tardivement lorsque c’est le cas. Une prise en soins psycho-médico-sociale individualisée peut favoriser l’insertion sociale et professionnelle et limiter le handicap. Une sensibilisation à ce syndrome de prévalence sous-estimée est nécessaire.</p></div><div><p>We present the case of a 27-year-old patient with severe developmental amnesia syndrome. This diagnosis is rarely made when young patients present with memory complaints, and when it is, it is usually made very late. Individualised psycho-medico-social care can promote social and professional integration and limit disability. There is a need to raise awareness of this syndrome, the prevalence of which is underestimated.</p></div>","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages 114-118"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sommaire","authors":"","doi":"10.1016/S1878-7762(24)00046-3","DOIUrl":"https://doi.org/10.1016/S1878-7762(24)00046-3","url":null,"abstract":"","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages iii-iv"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1878776224000463/pdfft?md5=8b2575c86bba288562399d2e547c8985&pid=1-s2.0-S1878776224000463-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141239503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pas si vite ! Succession rapide de crises après un arrêt cardiorespiratoire présumé","authors":"C.A. Teodorescu ,&nbsp;L. Vercueil","doi":"10.1016/j.praneu.2024.04.011","DOIUrl":"10.1016/j.praneu.2024.04.011","url":null,"abstract":"","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages 134-136"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enrayage cinétique (ou freezing of gait) sévère persistant en ON : essayez de diminuer la lévodopa !","authors":"M. Paumier ,&nbsp;P. Bernard ,&nbsp;T. Bogdan ,&nbsp;T. Wirth ,&nbsp;M. Anheim ,&nbsp;C. Tranchant","doi":"10.1016/j.praneu.2024.04.009","DOIUrl":"10.1016/j.praneu.2024.04.009","url":null,"abstract":"<div><p>Le gel de la marche (FOG) survient fréquemment au cours de l’évolution de la maladie de Parkinson et participe à la dépendance de ces patients. Les formes cliniques les plus fréquentes sont le FOG OFF, qui disparaît à l’état ON, et le FOG non dopa-sensible, qui persiste à l’état ON. Nous rapportons un cas rare de FOG ON induit par de fortes doses de lévodopa et disparaissant à l’état OFF. La physiopathologie pourrait être proche de la dyskinésie de pic de dose. Le traitement est difficile et sera discuté.</p></div><div><p>Freezing of gait (FOG) occurs frequently in the course of Parkinson's disease and participates in dependence of these patients. The most frequent clinical forms are OFF-FOG, which disappears in ON state, and unresponsive FOG, which persists in ON state. We report a rare case of ON-FOG, which was induced by high levodopa doses and disappeared in OFF state. Pathophysiology could be close to peak dose dyskinesia. Treatment is challenging and will be discussed.</p></div>","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages 119-121"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1878776224000384/pdfft?md5=cbc900b47bdd1d31dff8c72669643883&pid=1-s2.0-S1878776224000384-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141053322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommandations de la Société francophone de la sclérose en plaques « Vaccinations et sclérose en plaques » : mise à jour 2024","authors":"C. Lebrun-Frenay ,&nbsp;C. Carra-Dallière ,&nbsp;C. Louapre ,&nbsp;C. Papeix ,&nbsp;V. Pourcher ,&nbsp;X. Moisset ,&nbsp;E. Le Page ,&nbsp;E. Leray ,&nbsp;M. Cohen ,&nbsp;S. Vukusic ,&nbsp;pour le groupe F4MS-SFSEP","doi":"10.1016/j.praneu.2024.04.001","DOIUrl":"10.1016/j.praneu.2024.04.001","url":null,"abstract":"<div><p>Le groupe français pour les recommandations de la SFSEP a mis à jour les recommandations « Vaccinations et SEP » publiées en 2019. Cette mise à jour tient compte de la littérature récente, mais aussi de l’arrivée de nouvelles molécules, ou de situations particulières non abordées dans les précédentes recommandations (femmes enceintes, enfants, personnes âgées, voyageurs, COVID-19). Il est important que les médecins et les patients soient bien informés des mises à jours disponibles des recommandations vaccinales.</p></div><div><p>The French Group for Recommendations for Multiple Sclerosis (France4MS) for the French MS Society (SFSEP) updated its 2019 recommendations on immunization for patients with multiple sclerosis (MS). This update includes the most recent available immunoreactive treatments and specific situations (pregnancy, childhood, elderly patients, travelers, and COVID-19). Physicians and patients should be aware of the updated recommendations for immunizations of patients with MS.</p></div>","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Pages 105-113"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Désenchanter et enchanter par cette lecture le corps ! À propos de Frédérique de Vignemont. Désenchanter le corps. Aux origines de la conscience de soi. Paris: éditions Odile Jacob, 2023","authors":"C. Thomas-Anterion","doi":"10.1016/j.praneu.2024.04.006","DOIUrl":"10.1016/j.praneu.2024.04.006","url":null,"abstract":"","PeriodicalId":53613,"journal":{"name":"Pratique Neurologique - FMC","volume":"15 2","pages":"Page 140"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}