Tit-Kei Ng, Tommy King-Him Ma, Chi-Chun Au, Janice Woon-Yan Wong, Jenny Nga-Lai Chow, A. V. Li, Adrian Yin-Cheung Luk, Sze-Wah Lai, Candy Ming-Yan Cheuk, Jaclyn Chan, L. Tam
{"title":"Old but not Vain : Two Cases of Refractory Polymorphic Ventricular Tachycardia associated with Coronary Artery Disease successfully treated with Quinidine","authors":"Tit-Kei Ng, Tommy King-Him Ma, Chi-Chun Au, Janice Woon-Yan Wong, Jenny Nga-Lai Chow, A. V. Li, Adrian Yin-Cheung Luk, Sze-Wah Lai, Candy Ming-Yan Cheuk, Jaclyn Chan, L. Tam","doi":"10.55503/2790-6744.1496","DOIUrl":"https://doi.org/10.55503/2790-6744.1496","url":null,"abstract":"Post-myocardial infarction polymorphic ventricular tachycardia (VT) triggered by injured Purkinje fi bres can cause VT storms that are refractory to various treatment even after successful reperfusion or revascularization. We report recurrent polymorphic VT in two post-myocardial infarction patients after percutaneous coronary intervention. Both of them responded readily to Quinidine. We also discussed the pathophysiology of this arrhythmia and the treatment options for it, namely catheter ablation and anti-arrhythmic drugs","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":"14 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41264571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective observational study comparing two reperfusion strategies in patients with acute STEMI presenting outside office hours","authors":"D. Lee, K. Chan, M. Lee, Eric C.Y. Wong","doi":"10.55503/2790-6744.1494","DOIUrl":"https://doi.org/10.55503/2790-6744.1494","url":null,"abstract":"Introduction : A pilot cluster-based 24-hour primary percutaneous coronary intervention (PPCI) service in a phased expansion program was launched in October 2018. This study aimed to compare the 30-day mortality and major bleeding event in acute ST-elevation myocardial infarction (STEMI) patients presenting outside of fi ce hours who received historical thrombolytic therapy and PPCI under the newly implemented 24-hour service model. Methods and results : A single center retrospective study was conducted on consecutive STEMI patients presenting outside of fi ce hours, who received urgent thrombolytic therapy or PPCI between 2016-2019. The primary endpoints were 30-day mortality and major bleeding event. The secondary endpoints were thrombolytic failure rate and hospital length of stay. A total of 331 patients were analyzed. 30-day mortality occurred in 11.7% in thrombolytic group and 4.2% in PPCI group ( P ¼ .02). Major bleeding events occurred in 8% in thrombolytic group and 2.1% in PPCI group ( P ¼ .02). Multivariate analysis identi fi ed age ≥ 75 as an independent factor associated with major outcomes. Thrombolytic failure occurred in 31.4% of patients. The median lengths of stay were not different between the two groups (5 vs 4 days, P ¼ .29). Conclusions : Compared with thrombolytic therapy, PPCI in patients with acute STEMI presenting outside of fi ce hours is associated with lower risks of 30-day mortality and major bleeding event. Age ≥ 75 was an independent risk factor associated with mortality and bleeding outcome.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44606387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilisation of the simplified pulmonary embolism severity index in prognostication of pulmonary embolism – a retrospective study in a regional hospital in Hong Kong","authors":"Ka-Hung Lau, Chi-Suen Chiu, Liang Chow, Ngai-Yin Chan","doi":"10.55503/2790-6744.1516","DOIUrl":"https://doi.org/10.55503/2790-6744.1516","url":null,"abstract":"Pulmonary embolism is the most severe form of venous thromboembolism that can result in significant morbidity and mortality, especially if left untreated. Guidelines suggested the use of clinical scoring systems to stratify patients’ risk of mortality, which helps to guide subsequent management strategy. Simplified pulmonary embolism severity index is a well-validated prognostic score that predicts the risk of short term mortality of pulmonary embolism and studies showed that low-risk patients could be safely managed as outpatients. However, local studies on the use of prognostic scores including simplified pulmonary embolism severity index in management of pulmonary embolism are lacking.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Clinical Outcomes of Covid-19 Infection with Pre-existing Heart Failure – A Scientific Review","authors":"Ka-Yi Chan, Hiu-Ching Chan, Calvin Ka-Lam Leung, Qing-Wen Ren, Kai-Hang Yiu","doi":"10.55503/2790-6744.1512","DOIUrl":"https://doi.org/10.55503/2790-6744.1512","url":null,"abstract":"The COVID-19 pandemic has caused major impact to our world in various aspects. Healthy individuals infected with COVID-19 often develop different complications, even more so for patients with medical comorbidities. Various reports and studies have suggested cardiovascular disease as one of the major comorbidities in patients with COVID, and COVID infection could be life threatening in patients with pre-existing heart diseases, such as heart failure. In view of such, we aim to review on the subset of COVID patients who have pre-existing heart failure, in terms of in-hospital mortality, delivery of in-patient care and in-hospital complications. In conclusion, heart failure patients have a high mortality rate, a high risk of developing complications and require more healthcare resources. More hospital care is needed, with more advanced nursing and rehabilitation care. Heparin and corticosteroids can be considered to lower the complication and mortality rate, and telecommunication may be a useful adjunct to lower the healthcare-related costs.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136307782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Tse, H. Li, C. Leung, Siyun Yu, Jiayi Huang, Q. Ren, Mei-Zhen Wu, H. Tse, K. Yiu
{"title":"Association of Effective Regurgitant Orifice Area to Tricuspid Annular Plane Systolic Excursion Ratio with Outcomes After Tricuspid Annuloplasty","authors":"Y. Tse, H. Li, C. Leung, Siyun Yu, Jiayi Huang, Q. Ren, Mei-Zhen Wu, H. Tse, K. Yiu","doi":"10.55503/2790-6744.1511","DOIUrl":"https://doi.org/10.55503/2790-6744.1511","url":null,"abstract":"Background : Assessment of secondary tricuspid regurgitation (TR) severity does not correct for right heart function. We hypothesized that TR severity may be proportional or disproportional to the degree of right ventricular dysfunction and investigated its prognostic implications in patients undergoing tricuspid annuloplasty. Methods : The ratios of pre-procedural effective regurgitant ori fi ce area (EROA) with tricuspid annular plane systolic excursion (TAPSE) were retrospectively assessed in 290 patients undergoing tricuspid annuloplasty. The optimal threshold of EROA/TAPSE ratio associated with increased risk for adverse events was derived from maximally selected rank statistics. Results : The cutoff value of EROA/TAPSE ratio associated with an excess risk of adverse events was 3.42, and 104 (36%) had EROA/TAPSE ratios > 3.42. Compared to those with EROA/TAPSE ratios ≤ 3.42, patients with EROA/TAPSE ratios > 3.42 had a higher prevalence of moderate-to-severe aortic stenosis, a lower prevalence of moderate-to-severe mitral regurgitation, larger right heart dimensions, and more exaggerated tricuspid lea fl et displacement. Over a 4.1-year median follow-up, 79 adverse events (47 heart failure hospitalizations and 32 deaths) occurred. Patients with EROA/TAPSE ratios > 3.42 had higher rates of adverse events than those with EROA/TAPSE ratios ≤ 3.42 (44% vs 18%; P < 0.001) and were independently associated with poor outcomes on multivariate analysis. TR proportionality provided incremental prognostic value to both the EuroSCORE II and STS score (incremental c 2 ¼ 23.510 and 20.616 respectively; P < 0.05). Conclusions : EROA/TAPSE ratio > 3.42 is independently associated with adverse prognosis in patients undergoing tricuspid annuloplasty. Characterization of TR severity to RV function may improve patient selection and risk strati fi - cation for tricuspid annuloplasty.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45590114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endovenous Intervention: From the Legs to the Lungs","authors":"G. Tan, B. Yan","doi":"10.55503/2790-6744.1508","DOIUrl":"https://doi.org/10.55503/2790-6744.1508","url":null,"abstract":"Signi fi cant advancement in endovascular technology have enabled the treatment of a variety of venous diseases from the deep vein diseases to diseases in the pulmonary vasculatures. Understanding the principles and the limitations of these endovenous interventions is very important in selecting the appropriate patients for optimal clinical outcomes. In this review, the clinical evidence, guideline recommendations from various societies and the approaches to these endovenous procedures will be discussed.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48111650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Telltale of Left Atrial Thrombus Formation in Mitral Stenosis: Revisiting the Virchow’s Triad","authors":"Bayushi Eka Putra, Rina Ariani, Anwar Santoso, Prima Almazini, Estu Rudiktyo, Amiliana Mardiani Soesanto","doi":"10.55503/2790-6744.1514","DOIUrl":"https://doi.org/10.55503/2790-6744.1514","url":null,"abstract":"Aims: This study was conducted to assess the relationship of simple hematological parameters with the incidence of left atrial thrombus in rheumatic mitral stenosis in addition to conventional contributing factors. Methods: A cross-sectional analytical study was conducted in patients with significant rheumatic stenosis from 1 January 2018 to 31 July 2021. Thrombus evaluation was confirmed by transthoracic or transesophageal echocardiography. Lab tests were performed within 10 days prior to the echocardiographic evaluation. Subjects with significant mitral regurgitation will be excluded. Logistic regression analysis was done to evaluate the relationship between each variable to the presence of a thrombus. Results: Of the 318 subjects with significant rheumatic mitral stenosis included in the study, 102 patients (32%) had a thrombus in the left atrium. Of all the patients, it was known that subjects with atrial fibrillation rhythm as much as 63.8% and sinus rhythm 36.2%. Atrial fibrillation rhythm (OR 2.39; 95% CI 1.10-5.20, p = 0.028), left ventricular ejection fraction ≥56.68 % (OR 0.42; 95% CI 0.23 - 0.77, p = 0.005), TAPSE ≥18.10 mm (OR 0.44; 95% CI 0.230 - 0.83, p = 0.011), and hematocrit ≥45.15% (OR 2.98; 95% CI 1.27 - 6.98, p = 0.012) are associated with left atrial thrombus. Conclusion: Increased hematocrit was significantly associated with the incidence of left atrial thrombus, which may have contributed to the statis and hypercoagulable state component of the Virchow’s triad.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"24th ASC of ICSM Abstracts","authors":"","doi":"10.55503/2790-6744.1488","DOIUrl":"https://doi.org/10.55503/2790-6744.1488","url":null,"abstract":"","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44191593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"24th ASC of ICSM Proceedings","authors":"","doi":"10.55503/2790-6744.1490","DOIUrl":"https://doi.org/10.55503/2790-6744.1490","url":null,"abstract":"","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45496927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The development and growth of cardio-oncology or onco-cardiology","authors":"B. Cheung, C. Lau","doi":"10.55503/2790-6744.1473","DOIUrl":"https://doi.org/10.55503/2790-6744.1473","url":null,"abstract":"","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46399828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}