International Journal of Biology and Biomedical Engineering最新文献

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Changes in Red Blood Cell Membrane Properties: The Role of Metabolic Syndrome Components 红细胞膜性质的变化:代谢综合征成分的作用
International Journal of Biology and Biomedical Engineering Pub Date : 2021-06-21 DOI: 10.46300/91011.2021.15.26
Yuliya Birulina, I. Petrova, V. V. Ivanov, E. Buyko, R. R. Shaibekova, A. Grigoreva, I. Kovalev, A. Nosarev, S. Gusakova
{"title":"Changes in Red Blood Cell Membrane Properties: The Role of Metabolic Syndrome Components","authors":"Yuliya Birulina, I. Petrova, V. V. Ivanov, E. Buyko, R. R. Shaibekova, A. Grigoreva, I. Kovalev, A. Nosarev, S. Gusakova","doi":"10.46300/91011.2021.15.26","DOIUrl":"https://doi.org/10.46300/91011.2021.15.26","url":null,"abstract":"Metabolic syndrome (MetS) is a cluster of metabolic, hormonal and hemodynamic disorders that contribute to a change in the structural and functional status of erythrocytes and contribute to dysregulation of their cation transport function, where Ca2+ -dependent potassium channels (KCa channels) play an important role. A MetS model was performed using male Wistar rats, which were divided into control and experimental groups. Rats in the control group were fed standard rat chow. Rats in the experimental group were exposed to a high-fat and high-carbohydrate (HFHC) diet for 12 weeks. The data obtained indicate that the HFHC diet led to obesity, high blood pressure, hyperglycemia, impaired glucose tolerance, and dyslipidemia. The level of glutathione (GSH) decreased in the erythrocytes of rats suffering from MetS, but the level of malondialdehyde (MDA) increased. It was shown that the amplitude of the membrane potential of erythrocytes of rats with MetS changed depending on the acting agent: when stimulated with calcium ionophore A23187 it decreased, when the redox system ascorbat –phenazine methosulfate was used, it increased compared to the control group. The data obtained indicate that a HFHC diet leads to changes in the physical and chemical properties of the erythrocyte membrane.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47230845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of Polymorphic Marker of Genes of the Renin-angiotensin System RAS (AGT, AGTR1, АСЕ), ITGB3, PPARG) in Pa-tients With Essential Arterial Hypertension Depending on the Nature of the Nocturnal De-crease of BP 肾素-血管紧张素系统RAS (AGT, AGTR1, АСЕ), ITGB3, PPARG)基因多态性标记在原发性高血压患者夜间血压降低性质中的分布
International Journal of Biology and Biomedical Engineering Pub Date : 2021-06-03 DOI: 10.46300/91011.2021.15.24
T. Zotova, M. Azova, A. A. Lukanina, A. Aissa, M. Blagonravov
{"title":"Distribution of Polymorphic Marker of Genes of the Renin-angiotensin System RAS (AGT, AGTR1, АСЕ), ITGB3, PPARG) in Pa-tients With Essential Arterial Hypertension Depending on the Nature of the Nocturnal De-crease of BP","authors":"T. Zotova, M. Azova, A. A. Lukanina, A. Aissa, M. Blagonravov","doi":"10.46300/91011.2021.15.24","DOIUrl":"https://doi.org/10.46300/91011.2021.15.24","url":null,"abstract":"A clinical-genetic study using ABPM (24-hour BP monitoring) and Holter’s ECG methods in 49 pa-tients with essential arterial hypertension (group 1: 17 patients without sufficient nocturnal BP de-crease СI≤10%, and group 2: 32 patients with suf-ficient nocturnal BP decrease СI≥10%,) was per-formed for comparative analysis of the genotype frequencies of ACE, AGT, AGTR1, ITGB3, and PPARG. The study was conducted in order to clari-fy the pathogenetic mechanisms of the implementa-tion of different dynamics of nocturnal blood pres-sure in patients with hypertension without metabol-ic syndrome. It was found that in group 1, protec-tive genotype II of the ACE gene was more com-mon (p ≤ 0.025) than in the population data. A sig-nificant increase (p ≤ 0.025) in the frequency of the CC genotype of the AGTR1 gene responsible for the formation of insulin resistance compared to the population data was combined with a significant increase in the frequency of autonomic dysfunction in patients of group 1 - 83.4% vs. 64.5% group 2 respectively. The results obtained indicate the pos-sible pathogenetic links between genetically deter-mined insulin resistance and autonomic nervous system dysfunction and allows us to determine therapeutic approaches for correcting the noctur-nal blood pressure profile.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42826727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of COVID-19 on Mental Health COVID-19对心理健康的影响
International Journal of Biology and Biomedical Engineering Pub Date : 2021-06-03 DOI: 10.46300/91011.2021.15.23
Donart Koci, Festina Morina, Fatlinda Hoxhaj, Antigona Ukëhaxhaj
{"title":"The Impact of COVID-19 on Mental Health","authors":"Donart Koci, Festina Morina, Fatlinda Hoxhaj, Antigona Ukëhaxhaj","doi":"10.46300/91011.2021.15.23","DOIUrl":"https://doi.org/10.46300/91011.2021.15.23","url":null,"abstract":"Infection with the new coronavirus (severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The virus that causes COVID-19 spreads easily among humans and more continues to be detected over time as to how it spreads. The effect that this crisis will have on the mental health of the population, both in the short and long term, is unknown. In the acute phase, fears of possible exposure to infection, loss of employment, and financial strain are likely to increase psychological distress in the wider population. In the long run, grief and trauma are likely to appear as financial and social impacts become ingrained, the risk of depression and suicide may increase. Lack of hugs, handshakes, free movement and isolation have made it impossible for people to socialize and behave normally with each other. Anxiety, fear, insecurity and lack of self-confidence are some of the main problems that people faced during quarantine and that they may face after the release of the measures. The purpose of this paper is to prove how much the Pandemic and the situation with COVID-19 have affected the mental health of the population in the city of Prizren and Gjakova. Quantitative study method was used for the realization of this work. This paper is based on the data extracted from the questionnaire completed together with the citizens of the municipalities of Prizren and Gjakova. For the realization of this scientific research are involved 200 citizens. Age groups, gender, economic status, level of education and place of residence were analyzed. The study included people aged 20 to 50 years. The most included gender in the study is the female with 59% while the male gender with 41%. All results are presented in graphs worked with SPSS program.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43477638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
An Artificial Intelligence Approach Based on Hybrid CNN-XGB Model to Achieve High Prediction Accuracy through Feature Extraction, Classification and Regression for Enhancing Drug Discovery in Biomedicine 一种基于混合CNN-XGB模型的人工智能方法,通过特征提取、分类和回归实现高预测精度,增强生物医学中的药物发现
International Journal of Biology and Biomedical Engineering Pub Date : 2021-06-02 DOI: 10.46300/91011.2021.15.22
Mukesh Madanan, B. Sayed, Nurul Akhmal Mohd Zulkefli, Nitha C. Velayudhan
{"title":"An Artificial Intelligence Approach Based on Hybrid CNN-XGB Model to Achieve High Prediction Accuracy through Feature Extraction, Classification and Regression for Enhancing Drug Discovery in Biomedicine","authors":"Mukesh Madanan, B. Sayed, Nurul Akhmal Mohd Zulkefli, Nitha C. Velayudhan","doi":"10.46300/91011.2021.15.22","DOIUrl":"https://doi.org/10.46300/91011.2021.15.22","url":null,"abstract":"In the field of biomedicine, drug discovery is the cycle by which new and upcoming medicines are tested and invented to cure ailments. Drug discovery and improvement is an extensive, complex, and exorbitant cycle, settled in with a serious extent of vulnerability that a drug will really be successful or not. Developing new drugs have several challenges to enrich the current field of biomedicine. Among these ultimatums, predicting the reaction of the cell line to the injected or consumed drug is a significant point and this can minimize the cost of drug discovery in sophisticated fashion with a stress on the minimum computational time. Herein, the paper proposes a deep neural network structure as the Convolutional Neural Network (CNN) to detain the gene expression features of the cell line and then use the resulting abstract features as the input data of the XGBoost for drug response prediction. Dataset constituting previously identified molecular features of cancers associated to anti-cancer drugs are used for comparison with existing methods and proposed Hybrid CNNXGB model. The results evidently depicted that the predicted model can attain considerable enhanced performance in the prediction accuracy of drug efficiency.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45107104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Application of Organic and Inorganic Fertilizers Affects the Growth and Biomass Semanggi (Marsilea crenata Presl.) 有机肥和无机肥的施用对三芒吉(Marsilea crenata Presl.)生长和生物量的影响
International Journal of Biology and Biomedical Engineering Pub Date : 2021-05-17 DOI: 10.46300/91011.2021.15.19
Mustika Tripatmasari, A. Ariffin, E. Nihayati, M. Agil
{"title":"Application of Organic and Inorganic Fertilizers Affects the Growth and Biomass Semanggi (Marsilea crenata Presl.)","authors":"Mustika Tripatmasari, A. Ariffin, E. Nihayati, M. Agil","doi":"10.46300/91011.2021.15.19","DOIUrl":"https://doi.org/10.46300/91011.2021.15.19","url":null,"abstract":"Semanggi (Marsilea crenata Presl.) is one of the aquatic plants that have been widely used by the community as food and medicinal raw materials. One of the important factors in cultivating clover is optimal fertilizer management. The incorporation of organic and inorganic nutrients has an effect on soil fertility has been repeatedly demonstrated in several studies, but there are not specific guidelines on clover cultivation. The challenge now is to combine organic matter of different qualities with inorganic fertilizers to optimize nutrient availability for the clover plant. The results of research on clover cultivation have also not been widely carried out. Therefore, it is very important to do this research with the aim of knowing the optimal effect of organic (cow manure) and inorganic (nitrogen, potassium) fertilizers on the growth and yield of clover (Marsilea crenata Presl.). The research was conducted at the Screen House of the Faculty of Agriculture, Brawijaya University. The study was designed using a non-factorial randomized block design (RBD) with 8 (eight) treatment combinations of soil types and fertilization [inorganic (N, K) cow manure organic fertilizer (CM)], namely: P0 = soil, without fertilizer; P1 = soil, 138 kg N ha-1; P2 = soil, 136 kg K ha-1; P3 = soil, N and K, 138 and 136 kg ha-1; P4 = soil, 20x103kg of cow manure ha-1; P5 = soil, 20x103 kg of cow manure ha-1, 138 kg N ha-1; P6 = soil, 20x103 kg of cow manure ha-1, 136 kg K ha-1; P7 = soil, 20x103 kg of cow manure ha-1, N and K, 138 and 136 kg ha-1 with 3 replications, so that 24 experimental units were obtained. Each experimental unit consisted of 5 plants. Growth observations were observed destructively at the ages of 4, 8, 12, 16, 20, 24, 28, 32 days after planting (DAP). The results showed that there was an increase in the growth and yield of biomass in the soil combination, 20x103 kg of cow manure ha-1 (P4) was compared with the treatment without the addition of organic fertilizers (cow manure) on plant growth and yield parameters, such as stolon length (74.78 cm), number of leaves (160.44), leaf area (1379.28 cm2), root length (23.85 cm), stomata density and number of stomata (13.25); Stomata width (10.87 cm); Stomata length (19.76 cm), leaf fresh weight (12,907 g), leaf dry weight (1,802 g), total fresh weight 210,830 g, total dry weight 7,823 g, leaf harvest fresh weight (64.19 g); stalk (130.54 g); root (79.75 g); total 274.48 g), harvest dry weight of leaves (11.36 g); stalk (24.88 g); root (9.55 g); a total of 45.78 g) and the chlorophyll a content (0.804 mg.g-1); chlorophyll b (1.121mg.g-1); and total chlorophyll (1.924 mg.g-1).","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48289435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Characteristic of Microphyta Distribution of Pager River, Central Kalimantan 加里曼丹中部佩格尔河小生植物分布特征
International Journal of Biology and Biomedical Engineering Pub Date : 2021-05-17 DOI: 10.46300/91011.2021.15.20
Inga Torang, S. Gumiri, Ardianoor Ardianoor, A. Jaya
{"title":"Characteristic of Microphyta Distribution of Pager River, Central Kalimantan","authors":"Inga Torang, S. Gumiri, Ardianoor Ardianoor, A. Jaya","doi":"10.46300/91011.2021.15.20","DOIUrl":"https://doi.org/10.46300/91011.2021.15.20","url":null,"abstract":"Environmental damage due to natural resource extraction, especially in watershed areas, seems to be of increasing concern and so far, from the aspect of aquatic and water resources, plankton is commonly used as an indicator of environmental damage. This study explores the distribution of microphyta as a parameter of environmental damage. The research was conducted in Pager watershed, Central Kalimantan and sampled at 2 (two) stations, namely station A (for the right side of the river) and station B (for the left side of the river). The study was conducted 13 sampling times, which began in the period 25 May 2019 ending until 9 November 2019. Laboratory analysis to identify the type and number of microphyta was carried out at the Palangka Raya University Laboratory. The results showed that the number of microphyta taxa at station A (right side of the river) was 12-13 species, more than station B (left side of the river). The number of microphyta taxa at Station B is 8 - 9 species, it is suspected that there is an influence from the gray water settlements around the left side, especially when the water level drops. The distribution characteristics of microphyta in the Pager river are as follows: large number of taxa/species, low abundance and low diversity index. River/peat water environments are vulnerable to change, especially human interference. This research shows the potential use of microphyta as an indicator of environmental damage.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44113227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Security Provisioning and Compression of Diverse Genomic Data based on Advanced Encryption Standard (AES) Algorithm 基于高级加密标准(AES)算法的多种基因组数据的安全配置与压缩
International Journal of Biology and Biomedical Engineering Pub Date : 2021-05-14 DOI: 10.46300/91011.2021.15.14
Raveendra Gudodagi, R. Reddy
{"title":"Security Provisioning and Compression of Diverse Genomic Data based on Advanced Encryption Standard (AES) Algorithm","authors":"Raveendra Gudodagi, R. Reddy","doi":"10.46300/91011.2021.15.14","DOIUrl":"https://doi.org/10.46300/91011.2021.15.14","url":null,"abstract":"Compression of genomic data has gained enormous momentum in recent years because of advances in technology, exponentially growing health concerns, and government funding for research. Such advances have driven us to personalize public health and medical care. These pose a considerable challenge for ubiquitous computing in data storage. One of the main issues faced by genomic laboratories is the 'cost of storage' due to the large data file of the human genome (ranging from 30 GB to 200 GB). Data preservation is a set of actions meant to protect data from unauthorized access or changes. There are several methods used to protect data, and encryption is one of them. Protecting genomic data is a critical concern in genomics as it includes personal data. We suggest a secure encryption and decryption technique for diverse genomic data (FASTA / FASTQ format) in this article. Since we know the sequenced data is massive in bulk, the raw sequenced file is broken into sections and compressed. The Advanced Encryption Standard (AES) algorithm is used for encryption, and the Galois / Counter Mode (GCM) algorithm, is used to decode the encrypted data. This approach reduces the amount of storage space used for the data disc while preserving the data. This condition necessitates the use of a modern data compression strategy. That not only reduces storage but also improves process efficiency by using a k-th order Markov chain. In this regard, no efforts have been made to address this problem separately, from both the hardware and software realms. In this analysis, we support the need for a tailor-made hardware and software ecosystem that will take full advantage of the current stand-alone solutions. The paper discusses sequenced DNA, which may take the form of raw data obtained from sequencing. Inappropriate use of genomic data presents unique risks because it can be used to classify any individual; thus, the study focuses on the security provisioning and compression of diverse genomic data using the Advanced Encryption Standard (AES) Algorithm.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48698231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structure of Hard And Soft Carapace Exoskeleton Biomaterial Through SEM-EDXRS at Various Stages of Development Scylla paramamosain Mud Crab 用SEM-EDXRS研究硬、软甲壳类外骨骼生物材料在不同发育阶段的结构
International Journal of Biology and Biomedical Engineering Pub Date : 2021-05-14 DOI: 10.46300/91011.2021.15.15
H. Triajie, S. Andayani, U. Yanuhar, A. Ekawati
{"title":"Structure of Hard And Soft Carapace Exoskeleton Biomaterial Through SEM-EDXRS at Various Stages of Development Scylla paramamosain Mud Crab","authors":"H. Triajie, S. Andayani, U. Yanuhar, A. Ekawati","doi":"10.46300/91011.2021.15.15","DOIUrl":"https://doi.org/10.46300/91011.2021.15.15","url":null,"abstract":"Crustacean carapace has various functions which can be seen from the composition of the biomaterial in it. Various concentrations of inorganic biomaterial elements were investigated from the hard carapace and the newly molted (soft-shelled) (Scylla paramamosain) with SEM-EDXRS (scanning electron microscopy-Energy Dispersive X-ray Spectrometer) technique. This study traced the composition of the inorganic elements of the premolt, postmolt, intermolt and soft (exuvium) crab hard carapace tissue of mangrove crabs from the point of view. Various stages of development. Important elements such as C, O2, Mg, P, Ca, S, Na, Si, Cl, and others, are reabsorbed from the carapace into the body tissues to fulfill further needs in soft-shelled crabs and are reused to some extent during formation new carapace. This study provides evidence that, inorganic elements in freshly molted soft carapace crabs are less common than hard carapace crabs","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45700475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Features of Antigen Prevalence of Rhesus System in Donor Population 供体人群恒河猴系统抗原流行特征分析
International Journal of Biology and Biomedical Engineering Pub Date : 2021-04-15 DOI: 10.46300/91011.2021.15.10
M. Nagervadze, L. Akvlediani, I. Tsintsadze, T. Koiava, R. Loria, S. Tskvitinidze, R. Khukhunaishvili, M. Koridze
{"title":"The Features of Antigen Prevalence of Rhesus System in Donor Population","authors":"M. Nagervadze, L. Akvlediani, I. Tsintsadze, T. Koiava, R. Loria, S. Tskvitinidze, R. Khukhunaishvili, M. Koridze","doi":"10.46300/91011.2021.15.10","DOIUrl":"https://doi.org/10.46300/91011.2021.15.10","url":null,"abstract":"Research materials and methods. 852 voluntary Georgian blood donors have been typed on red blood cells group antigens. The research materials have taken from the diagnostic laboratory of Health Centre of Batumi (Georgia republic). The immunoserological methods with monoclonal anti –AB, -B, -A, A1, -A2 (H), -C, -c, - D, -E, -e (Bio-Rad, cypress diagnostics) antibodies was used for typing blood. The ID cards, such as ABO/D + Reverse Grouping (Bio-Rad) were also used for typing of erythrocyte antigens. Result. Prevalence of Rh system antigens in the studied group is looks like so: e antigens – 94,6%, c antigens -85%, C-68,03, E antigens - 38,07%. The majority (84%) of the studied donors are Rh-positive (n=719), 133 (16%) donors are Rh-negative. C antigen most common is present in the combination with D antigen. 65, 8 % case donors had CD+ combination (n=561). E antigen in most cases is presented with a combination of D antigen. 36, 9% of the studied donors (n=306) had ED+ combination. A miserable number of studied donors had CD - (2,23%; n=19) and ED - (1,17%; n=9) combinations. We have studied the Rh phenotypes prevalence in blood donors. According to RHD, RHC, and RHE gene loci, there are 18 theoretically possible phenotypical groups. Among them half (nine) are Rh-positive and the rest of them are Rh-negative. The Rh-positive phenotypes are: CDE; CDEe; CDe; CcDE; CcDEe; CcDe; ccDE; cDEe and cDe. Rh-negative phenotypes are CdE; CdEe; Cde; CcdE; CcdEe; Ccde; cdE; cdEe; cde. We allocated 17 Rh phenotypes among studied donors. Only one phenotype CdE, which belongs to Rh negative group, was not present in studied donors. Other 17 phenotypes showed different frequencies. Some of them were only in a single case, for example, cdEe, cdE, CdEe phenotypes had only one donor. The majority of the phenotype in he studied donors (27,8±1,53%) was CcDe (n=237). CcDEe -19,3±1,35% (n=165); 125 donors have CDe phenotype (14,6±1,2); The frequency of cde was 13,1±1,5%, which means that 112 studied donors belonged to this phenotype group; 87 studied donors had cDEe phenotype characteristics (10,2%); The frequency of cDe was 4,9% (n=42); 19 donors had CDEe phenotype. Other phenotypes (CDE, Cde, CcdEe, Ccde) frequency was very low. Conclusion. Our studied donors are characterized by rather high polymorphism. The Georgian donor’s population is heterogenic, especially high heterogeneity are shown in Rh positive phenotypes. The obtained data is vital importance for the preparation of whole blood or certain blood components for the purpose of their rational usage in blood transfusion.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45771404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Policy Priorities For Improving The Quality Of Slum Settlements In Banjarmasin City, South Kalimantan Province, Indonesia 改善印尼南加里曼丹省班加马辛市贫民窟住区质量的政策重点
International Journal of Biology and Biomedical Engineering Pub Date : 2021-04-08 DOI: 10.46300/91011.2021.15.9
F. Yusran
{"title":"Policy Priorities For Improving The Quality Of Slum Settlements In Banjarmasin City, South Kalimantan Province, Indonesia","authors":"F. Yusran","doi":"10.46300/91011.2021.15.9","DOIUrl":"https://doi.org/10.46300/91011.2021.15.9","url":null,"abstract":"Banjarmasin city faces almost the same problems as other big cities in the world, namely slum settlements. One of the factors in the formation of slum settlements in Banjarmasin city is urbanization. The population that continues to increase due to the flow of urbanization causes urban areas to have a very urgent problem, namely the provision of housing facilities. The high price of land in the city center and low-per capita income cause people to tend to look for settlements in suburban areas with inadequate environments and supporting facilities. This research aims to identify the conditions of slum settlements in Banjarmasin City and formulate policy priorities to improve the quality of slum settlements in Banjarmasin City. To answer all these objectives, an integrated settlement management system can be implemented. Comprehensive integration between office holders, stakeholders, and residents will produce a draft policy and slum management scenario. In addition, the policy for sustainable management of slum settlements in Banjarmasin City is also designed using the AHP (Analytical Hierarchy Process) approach. The slum settlements in Banjarmasin city are generally caused by geographical location, where most of them are river and swamp areas. Slums are getting worse because of the bad sanitation system. Ecological factor is the main priority factor in improving the quality of slum settlements. This is because if the slum area is able to maintain its ecology, it will be able to overcome disturbances or pressure, maintain or regain its function and shape. Based on AHP analysis, it is also known that the policy priority in improving the quality of slum settlements is by redevelopment. This effort is the rearrangement of part or all of the area for the purpose of managing the slum settlements in Banjarmasin city.","PeriodicalId":53488,"journal":{"name":"International Journal of Biology and Biomedical Engineering","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70491221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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