{"title":"Global facial rejuvenation with one treatment of incobotulinumtoxinA, hyaluronic acid, and calcium hydroxyapatite results in long-term patient-reported satisfaction.","authors":"Jasmine Thai Lu, Kachiu C Lee","doi":"10.1097/JW9.0000000000000124","DOIUrl":"10.1097/JW9.0000000000000124","url":null,"abstract":"<p><strong>Background: </strong>Global facial rejuvenation using injectables (neuromodulators and fillers) has reported patient satisfaction after 2 treatments: an initial and touch-up treatment at 2-4 weeks afterward. In practice, patients typically receive only 1 treatment and do not return for a touch-up treatment within a month.</p><p><strong>Objective: </strong>The purpose of this study was to assess patient-reported satisfaction after only 1 treatment, thus mimicking real-world scenarios.</p><p><strong>Methods: </strong>Patients with facial photoaging (Glogau facial aging scale ≥2) were treated with calcium hydroxyapatite, hyaluronic acid 22.5 mg/mL, and incobotulinumtoxinA injections for full facial rejuvenation, with no touch-up treatments. Patients completed the FACE-Q Satisfaction with Facial Appearance survey at baseline and 1- and 3-month post-treatment. The treating physician completed the Global Aesthetic Improvement Scale at 1- and 3-month post-treatment.</p><p><strong>Results: </strong>Twenty-two patients were enrolled in the study, with 1 patient lost to follow-up. There was a significant improvement in mean FACE-Q scores at 1-month (80.1, <i>P</i> = .01) and 3-month (77.9, <i>P</i> = .02) compared to baseline (71.4). Mean Global Aesthetic Improvement Scale scores at 1-month (2.1) and 3-month (2.2) were not statistically significant, indicating sustained improvement at 3 months. The product amount used per patient varied and was not correlated with either score. Limitations included a lack of a control group and follow-up ending at 3 months. Strengths included assessment of patient satisfaction after only 1 treatment, compared to other studies allowing 2 treatments.</p><p><strong>Limitations: </strong>Limitations include a small sample size and lack of a control group.</p><p><strong>Conclusion: </strong>Global full facial rejuvenation using 1 treatment of calcium hydroxyapatite, hyaluronic acid 22.5 mg/mL, and incobotulinumtoxinA provides sustained patient-reported satisfaction at 3 months.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e124"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amar D Desai, Jacquelyn M Roth, Nilesh Kodali, Simona Alomary, Rahul Bhatia, Vinod E Nambudiri, Cindy Wassef, Shari R Lipner
{"title":"Venture capital funding of dermatology companies founded by women: a unique set of challenges.","authors":"Amar D Desai, Jacquelyn M Roth, Nilesh Kodali, Simona Alomary, Rahul Bhatia, Vinod E Nambudiri, Cindy Wassef, Shari R Lipner","doi":"10.1097/JW9.0000000000000120","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000120","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e120"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lina Alhanshali, Fatima Bawany, Michael G Buontempo, Jerry Shapiro, Kristen Lo Sicco
{"title":"Understanding perceptions of hair loss in hijab-wearing women: a pilot survey study.","authors":"Lina Alhanshali, Fatima Bawany, Michael G Buontempo, Jerry Shapiro, Kristen Lo Sicco","doi":"10.1097/JW9.0000000000000115","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000115","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e115"},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jazmin Newton, Allen Wellman, Lauren Ochoa, Alyssa Reinschmidt, Samuel John Vassar, Minga Vargas, DenYelle B Kenyon, Marcus Frohm
{"title":"Young women in sororities more likely to have used tanning beds and report improved appearance and self-confidence with tan skin.","authors":"Jazmin Newton, Allen Wellman, Lauren Ochoa, Alyssa Reinschmidt, Samuel John Vassar, Minga Vargas, DenYelle B Kenyon, Marcus Frohm","doi":"10.1097/JW9.0000000000000116","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000116","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e116"},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alvaro Gonzalez-Cantero, María Magdalena Constantin, Annunziata Dattola, Tom Hillary, Elise Kleyn, Nina Magnolo
{"title":"Gender perspective in psoriasis: a scoping review and proposal of strategies for improved clinical practice by European dermatologists.","authors":"Alvaro Gonzalez-Cantero, María Magdalena Constantin, Annunziata Dattola, Tom Hillary, Elise Kleyn, Nina Magnolo","doi":"10.1097/JW9.0000000000000112","DOIUrl":"10.1097/JW9.0000000000000112","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of psoriasis is similar between men and women; however, evidence exists of sex- and gender-related differences in disease expression, impact, coping, and needs of patients with psoriasis. These differences are essential and should be considered in clinical practice and research.</p><p><strong>Objective: </strong>To compile available evidence on sex- and gender-related differences in psoriasis, identify the most critical gaps in clinical practice and research, and use it to propose strategies for improved clinical practice.</p><p><strong>Methods: </strong>Six European dermatologists selected the topics to consider according to their relevance in the dermatology setting with the support of methodologists. Evidence on sex- and gender-related differences was obtained by a scoping review based on search strategies in Medline and Cochrane Library from inception to October 2021 using the following terms: arthritis, psoriatic, psoriasis, gender, and sex. The panel discussed the results and proposed strategies by consensus.</p><p><strong>Results: </strong>The scoping review identified broad themes: (1) clinical expression, (2) severity and patient-reported outcomes, (3) psychosocial impact, (4) access to treatments and propensity to treat, (5) comorbidities, and (6) treatment effect. The strategies are based on these broad themes.</p><p><strong>Limitations: </strong>No risk of bias assessment was done due to the scoping nature of the review.</p><p><strong>Conclusion: </strong>This review offers insights into gender differences in psoriasis, providing a foundation for improving clinical practice and patient outcomes.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e112"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71429135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and phototrichogrammatic evaluation of estradiol replacement therapy on hair growth in postmenopausal Japanese women with female pattern hair loss: a pilot study.","authors":"Yujiro Endo, Yuko Obayashi, Michiaki Murakoshi, Juichiro Saito, Rie Ueki","doi":"10.1097/JW9.0000000000000109","DOIUrl":"10.1097/JW9.0000000000000109","url":null,"abstract":"<p><strong>Background: </strong>Female pattern hair loss (FPHL) is known to present with characteristic pathological conditions, including reduced overall hair density. Female hormones affect hair condition; however, the detailed mechanism is unknown. Furthermore, research on the topic is complicated by the fact that senescent alopecia often occurs concurrently with FPHL. Therefore, we investigated the effect of estradiol, a female hormone, on hair growth by eliminating aging factors and objectively evaluating hair changes caused by female hormone replacement therapy (HRT).</p><p><strong>Objective: </strong>This study was conducted to elucidate the mechanism through which female hormones exert their effects on hair.</p><p><strong>Methods: </strong>The study included 11 female patients undergoing HRT who were evaluated before initiating HRT, 3 months after initiating HRT, and 6 months after initiating HRT. The thinning hair score, hair density, telogen hair rate, telogen plucking strength, hair growth rate, and hair thickness were measured and evaluated. Furthermore, hematological tests were performed to assess the general physical condition of the participants.</p><p><strong>Results: </strong>HRT increased the telogen hair rate (<i>P</i> = .010, paired <i>t</i> test) at 3 months, improved frontal hairline thinning score (<i>P</i> = .008, Wilcoxon test), and increased the plucking strength (<i>P</i> = .013, paired <i>t</i> test) at 6 months.</p><p><strong>Limitations: </strong>The limitation of this study included the relatively small sample size, inability to conduct further long-term tests because of participant burden, and lack of a control group.</p><p><strong>Conclusion: </strong>The results suggested that HRT improved the appearance of the frontal hairline. As few studies have analyzed the effects of female hormones on human hair, a novel finding of this study was the effects of estradiol on the plucking strength after excluding age as a factor. We believe that these findings will contribute to understanding FPHL and developing female hormone-related treatments.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e109"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71429134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Taye, Nourine Ahmed Kamili, Crystal Aguh, Loren D Krueger
{"title":"Considerations and recommendations on camouflage in alopecia in Black women.","authors":"Marta Taye, Nourine Ahmed Kamili, Crystal Aguh, Loren D Krueger","doi":"10.1097/JW9.0000000000000111","DOIUrl":"10.1097/JW9.0000000000000111","url":null,"abstract":"<p><p>Alopecia is among the leading dermatological concerns affecting Black women. For many women, hair is a central component of identity and self-expression, the loss of which can have significant psychosocial effects. Hair camouflage is often utilized to minimize the visibility of hair loss, provide aesthetic benefits, and improve quality of life. The versatility and affordability of hair camouflage allows patients with alopecia to conceal hair loss, increasing self-confidence, and decreasing social stigma. However, hair camouflage practices often involve adhesives, chemicals, and/or high-tension braiding, all of which can exacerbate alopecia. Accordingly, special considerations should be made to protect patients' natural hair from damage while using these styling practices. A better understanding of best practices for some of the most widely used camouflage options-wigs, extensions, topical hair fibers, and micropigmentation-can help clinicians establish rapport with Black women and optimize individually-tailored therapeutic plans during active treatment and end-stage hair loss.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 3","pages":"e111"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/44/jw9-9-e111.PMC10550043.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41157225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors and comorbidities associated with central centrifugal cicatricial alopecia.","authors":"Maxwell Green, Aileen Feschuk, Manuel Valdebran","doi":"10.1097/JW9.0000000000000108","DOIUrl":"10.1097/JW9.0000000000000108","url":null,"abstract":"<p><p>Central centrifugal cicatricial alopecia (CCCA) is the most common form of scarring alopecia that most often affects Black women. The disease typically begins with hair loss in the center scalp, which progresses in a centripetal fashion. Both environmental insult and genetics have been implicated in CCCA etiology, although the exact pathophysiology remains unknown. Nevertheless, it is important that providers feel comfortable educating their patients on risk factors (RFs) for the development or worsening of CCCA, and potential comorbidities associated with the condition. Thus, the goal of this review was to summarize these factors. A comprehensive literature search was performed, and studies were included if they reported research on RFs for or comorbidities associated with, CCCA. A total of 15 studies were included: <i>n</i> = 5 researching RFs for CCCA and <i>n</i> = 10 researching comorbidities associated with CCCA. There was an association suggesting an increased risk of CCCA with traction hairstyles in <i>n</i> = 2/3 studies, previous pregnancies in <i>n</i> = 1/1 studies, and use of chemical hair relaxers in <i>n</i> = 1/3 studies. Additionally, age and total years of hair loss were associated with increased CCCA severity in <i>n</i> = 2/2 studies. Type 2 diabetes was positively associated with CCCA in <i>n</i> = 3/5 studies, uterine leiomyomas in <i>n</i> = 1/2 studies, hyperlipidemia in <i>n</i> = 1/2 studies, and vitamin D deficiency in <i>n</i> = 1/1 studies. Conflicting results regarding RFs and comorbidities associated with CCCA exist within the literature. Thus, further investigation in larger cohorts must be done, and future research into genes implicated in CCCA and their potential role in the development of other diseases is recommended.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 3","pages":"e108"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/f5/jw9-9-e108.PMC10513237.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lina Alhanshali, Michael G Buontempo, Fatima Bawany, Prince Adotama, Jerry Shapiro, Kristen Lo Sicco
{"title":"Religious headwear and alopecia: considerations for dermatologists.","authors":"Lina Alhanshali, Michael G Buontempo, Fatima Bawany, Prince Adotama, Jerry Shapiro, Kristen Lo Sicco","doi":"10.1097/JW9.0000000000000107","DOIUrl":"10.1097/JW9.0000000000000107","url":null,"abstract":"An estimated 84% of the global population identifies with a religious group.1 Wearing religious headwear has been associated with alopecia, most notably traction alopecia (Fig. 1). Traction alopecia can result from how the headwear is secured and styled, or other practices that may lead to tension on the hair and scalp. Individuals with alopecia who observe religious head coverings may struggle to conform to practices regarding headwear styling. As this topic is scarcely reported in the scientific literature, the authors relied on their personal experiences and expertise in treating hair and scalp disorders to provide recommendations for mitigating alopecia risk. Although no published clinical study directly implicates religious headwear in alopecia presentation, there is a strong discourse on headwear and hair loss. For example, Shareef et al.2 analyzed self-reported hijab-related alopecia content on YouTube and found 27 videos with a total of 17,158,078 views. Traction is a likely contributor to hijab-related alopecia, owing to the consistent and tight wrapping of the hijab around the head and hair, which can lead to continuous pull on the hair roots. This is a particularly important consideration for certain subgroups, such as women with afro-textured hair who have fewer elastic fibers attaching hair follicles to the dermis compared to Caucasians.3 In the Jewish tradition, wigs, known as sheitels, worn by Orthodox women may cause traction alopecia if they create tension on the scalp, particularly from wig attachment techniques. Wig placement often requires natural hair to be styled in a sleek, compact manner, promoting tight hair styling techniques such as buns and braids that can lead to alopecia. A case series on dermatologic considerations in ultra-Orthodox Jews reported a woman who presented with an alopecic patch in the frontal scalp where the sheitel clip was consistently placed.4 Hair regrew in the region after the patient transitioned to a clipless wig. Similarly, a study of 37 men with localized alopecic patches in the region of the pins used to secure their kippah showed that 58.8% of the patients who changed to a different type of pin fastener exhibited hair regrowth.5 Traction alopecia related to the turban or dastar, worn by Sikh men, has been reported in the scientific literature and is referred to as turban alopecia.1 This condition results from the tension caused by hairstyling and/or headwear styling. Sikh men generally style the hair in a bun or knot that is wrapped tightly with a cloth or scarf around the head. Tension can result from the bun itself, or from the turban being worn too tightly. The Rastafarian tradition encourages the growth of dreadlocks, which are considered a symbol of the Lion of Judah and a mark of African identity. The risk of traction alopecia can be influenced by the weight and length of dreadlocks as well as the tightness with which they are tied or wrapped under a headwrap. Recommendations for preven","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 3","pages":"e107"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10559804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Gold, Christina Huang, Rakan Radi, Pranav Gupta, Eric I Felner, Jeehea Sonya Haw, Krista Childress, Nancy Sokkary, Vin Tangpricha, Michael Goodman, Howa Yeung
{"title":"Dermatologic care of patients with differences of sex development.","authors":"Sarah Gold, Christina Huang, Rakan Radi, Pranav Gupta, Eric I Felner, Jeehea Sonya Haw, Krista Childress, Nancy Sokkary, Vin Tangpricha, Michael Goodman, Howa Yeung","doi":"10.1097/JW9.0000000000000106","DOIUrl":"10.1097/JW9.0000000000000106","url":null,"abstract":"<p><strong>Background: </strong>Differences of sex development (DSD or disorders of sex development) are uncommon congenital conditions, characterized by atypical development of chromosomal, gonadal, or anatomic sex.</p><p><strong>Objective: </strong>Dermatologic care is an important component of the multidisciplinary care needed for individuals with DSD. This article discusses the most common primary dermatologic manifestations of DSD in addition to the cutaneous manifestations of hormonal and surgical therapies in individuals with DSD.</p><p><strong>Data sources: </strong>Published articles including case series and case reports on PubMed.</p><p><strong>Study selections: </strong>Selection was conducted by examining existing literature with a team of multidisciplinary specialists.</p><p><strong>Methods: </strong>Narrative review.</p><p><strong>Limitations: </strong>This article was not conducted as a systematic review.</p><p><strong>Results: </strong>In Klinefelter syndrome, refractory leg ulcers and incontinentia pigmenti have been described. Turner syndrome is associated with lymphatic malformations, halo nevi, dermatitis, and psoriasis. Virilization can be seen in some forms of congenital adrenal hyperplasia, where acne and hirsutism are common.</p><p><strong>Conclusion: </strong>Dermatologists should consider teratogenic risk for treatments of skin conditions in DSD depending on pregnancy potential. Testosterone replacement, commonly used for Klinefelter syndrome, androgen insensitivity syndrome, 5-alpha reductase deficiency, gonadal dysgenesis, or ovotesticular DSD, may cause acne.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 3","pages":"e106"},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473340/pdf/jw9-9-e106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10522974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}