International Journal of Women''s Dermatology最新文献

{"title":"Atopic dermatitis in women: special considerations in the childbearing years.","authors":"Rodolfo Valentini, Mona Shahriari","doi":"10.1097/JW9.0000000000000151","DOIUrl":"10.1097/JW9.0000000000000151","url":null,"abstract":"<p><strong>Background: </strong>Atopic dermatitis (AD) is one of the most common inflammatory dermatoses in adults. Women are disproportionately impacted by AD and report significant impacts on quality of life compared to men.</p><p><strong>Objective: </strong>Given the absence of formal guidelines for the treatment of AD in women of childbearing age, we will review special considerations for treating women of childbearing age with AD to ensure consistent care and optimal outcomes for these patients.</p><p><strong>Methods: </strong>PubMed and Google Scholar databases were searched for relevant articles from database inception through May of 2023.</p><p><strong>Results: </strong>There are several treatments including topical therapies, systemic therapies, and phototherapy that are considered safe during preconception, pregnancy and breastfeeding. Given the negative consequences of uncontrolled AD for both the mother and the unborn baby, the risks and benefits of potential therapies should be reviewed with all women of childbearing age suffering from AD.</p><p><strong>Limitations: </strong>The gold standard in recommending therapies is randomized controlled trials; however, pregnant and lactating women are often excluded from these trials.</p><p><strong>Conclusion: </strong>Through shared decision-making between the dermatologist, obstetrician, and patient, the risks and benefits of any therapy should be thoroughly discussed and considered with all women of childbearing age, to optimize care and outcomes for this unique population.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 2","pages":"e151"},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11164005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in Janus kinase inhibitor access for alopecia areata: a retrospective analysis.","authors":"Elizabeth J Klein, Dolly Taiwò, Efe Kakpovbia, Melissa Laughter, Ambika Nohria, Kristen I Lo Sicco","doi":"10.1097/JW9.0000000000000155","DOIUrl":"10.1097/JW9.0000000000000155","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 2","pages":"e155"},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11164017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data wobbles in hidradenitis suppurativa clinical trials and potential contributing factors: a retrospective review.","authors":"Corey L Snyder, Ruby S Gibson, Stella X Chen, Martina L Porter, Alexa B Kimball","doi":"10.1097/JW9.0000000000000152","DOIUrl":"10.1097/JW9.0000000000000152","url":null,"abstract":"<p><strong>Background: </strong>In some hidradenitis suppurativa (HS) clinical trial study arms, there is an unexpected decline in efficacy between the penultimate visit and the prespecified primary endpoint week, which we have termed a \"wobble.\"</p><p><strong>Objective: </strong>We aimed to establish how often study arms in HS programs wobble.</p><p><strong>Methods: </strong>In a retrospective review, we identified HS clinical trials listed on ClinicalTrials.gov testing systemic, nonantibiotic medications that utilized Hidradenitis Suppurativa Clinical Response (HiSCR) as an outcome measure. We identified study arms demonstrating greater improvement in a visit prior to the primary endpoint week. Baseline subject characteristics were compared between studies with HiSCR wobble and no HiSCR wobble.</p><p><strong>Results: </strong>A total of 21 studies (randomized control trial [RCT], <i>n</i> = 14; open-label, <i>n</i> = 7) with 35 study drug arms (RCT, <i>n</i> = 27; open-label, <i>n</i> = 8) and 14 placebo arms were identified. HiSCR wobble occurred significantly more often in RCT compared to open-label study drug arms (11/27 [40.7%] vs 0/8 [0%]). In RCT study arms with HiSCR wobble, baseline draining fistula counts were significantly lower (2.3 vs 3.2), and numerically fewer Hurley stage 3 patients (33.2% vs 42.5%), lower weighted total abscess and nodule counts (12.1 vs 12.6), lower weighted dermatology life quality index scores (12.5 vs 14.5), and a higher proportion of female patients (63.9% vs 58.3%) were observed.</p><p><strong>Limitations: </strong>Include low number of HS clinical trials and insufficient data reported in many studies to assess for wobble, degree of wobble, and to compare all baseline characteristics.</p><p><strong>Conclusion: </strong>Nonlinear improvement in study arm response occurs in some HS RCTs. Potential contributing factors include a higher proportion of less severe patients at baseline and more female patients.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 2","pages":"e152"},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11161284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The three c's: vulvar exam terminology considerations for dermatologists.","authors":"Ellee P Vikram, Marianne R Rara, Christina N Kraus","doi":"10.1097/JW9.0000000000000147","DOIUrl":"10.1097/JW9.0000000000000147","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 2","pages":"e147"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11062684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spironolactone in hidradenitis suppurativa: a single-center.","authors":"Rahul Masson, Sarah E Park, Terri Shih, Marcia Hogeling, Vivian Y Shi, Jennifer L Hsiao","doi":"10.1097/JW9.0000000000000135","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000135","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 1","pages":"e135"},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating patients with hidradenitis suppurativa for disordered eating.","authors":"Amina Ziad, Yiwen Helen Li, Kristin N Javaras, Karla Santiago-Soltero, Alexandra Charrow","doi":"10.1097/JW9.0000000000000138","DOIUrl":"10.1097/JW9.0000000000000138","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 1","pages":"e138"},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global facial rejuvenation with one treatment of incobotulinumtoxinA, hyaluronic acid, and calcium hydroxyapatite results in long-term patient-reported satisfaction.","authors":"Jasmine Thai Lu, Kachiu C Lee","doi":"10.1097/JW9.0000000000000124","DOIUrl":"10.1097/JW9.0000000000000124","url":null,"abstract":"<p><strong>Background: </strong>Global facial rejuvenation using injectables (neuromodulators and fillers) has reported patient satisfaction after 2 treatments: an initial and touch-up treatment at 2-4 weeks afterward. In practice, patients typically receive only 1 treatment and do not return for a touch-up treatment within a month.</p><p><strong>Objective: </strong>The purpose of this study was to assess patient-reported satisfaction after only 1 treatment, thus mimicking real-world scenarios.</p><p><strong>Methods: </strong>Patients with facial photoaging (Glogau facial aging scale ≥2) were treated with calcium hydroxyapatite, hyaluronic acid 22.5 mg/mL, and incobotulinumtoxinA injections for full facial rejuvenation, with no touch-up treatments. Patients completed the FACE-Q Satisfaction with Facial Appearance survey at baseline and 1- and 3-month post-treatment. The treating physician completed the Global Aesthetic Improvement Scale at 1- and 3-month post-treatment.</p><p><strong>Results: </strong>Twenty-two patients were enrolled in the study, with 1 patient lost to follow-up. There was a significant improvement in mean FACE-Q scores at 1-month (80.1, <i>P</i> = .01) and 3-month (77.9, <i>P</i> = .02) compared to baseline (71.4). Mean Global Aesthetic Improvement Scale scores at 1-month (2.1) and 3-month (2.2) were not statistically significant, indicating sustained improvement at 3 months. The product amount used per patient varied and was not correlated with either score. Limitations included a lack of a control group and follow-up ending at 3 months. Strengths included assessment of patient satisfaction after only 1 treatment, compared to other studies allowing 2 treatments.</p><p><strong>Limitations: </strong>Limitations include a small sample size and lack of a control group.</p><p><strong>Conclusion: </strong>Global full facial rejuvenation using 1 treatment of calcium hydroxyapatite, hyaluronic acid 22.5 mg/mL, and incobotulinumtoxinA provides sustained patient-reported satisfaction at 3 months.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e124"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venture capital funding of dermatology companies founded by women: a unique set of challenges.","authors":"Amar D Desai, Jacquelyn M Roth, Nilesh Kodali, Simona Alomary, Rahul Bhatia, Vinod E Nambudiri, Cindy Wassef, Shari R Lipner","doi":"10.1097/JW9.0000000000000120","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000120","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e120"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding perceptions of hair loss in hijab-wearing women: a pilot survey study.","authors":"Lina Alhanshali, Fatima Bawany, Michael G Buontempo, Jerry Shapiro, Kristen Lo Sicco","doi":"10.1097/JW9.0000000000000115","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000115","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e115"},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Young women in sororities more likely to have used tanning beds and report improved appearance and self-confidence with tan skin.","authors":"Jazmin Newton, Allen Wellman, Lauren Ochoa, Alyssa Reinschmidt, Samuel John Vassar, Minga Vargas, DenYelle B Kenyon, Marcus Frohm","doi":"10.1097/JW9.0000000000000116","DOIUrl":"https://doi.org/10.1097/JW9.0000000000000116","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"9 4","pages":"e116"},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}