SanamedPub Date : 2022-06-02DOI: 10.5937/sanamed17-37207
Ivana Meta Jevtovic, Bojan Djokic, Miroslav S. Tomovic, Zorana Kovačević, Katarina M. Janicijevic
{"title":"A DEVELOPMENT OF SERBIAN MEDICINE IN THE 19TH CENTURY","authors":"Ivana Meta Jevtovic, Bojan Djokic, Miroslav S. Tomovic, Zorana Kovačević, Katarina M. Janicijevic","doi":"10.5937/sanamed17-37207","DOIUrl":"https://doi.org/10.5937/sanamed17-37207","url":null,"abstract":"With the fall of the medieval Serbian state under Turkish rule, every culture, including medicine, died out, and the people resorted to folk medicine and self-taught doctors, i.e. empiricists. Serbs began to get educated in Vienna and Pest, and there were Serbian doctors in Novi Sad already at the beginning of the 18th century. At that time, the first doctors with diplomas appeared in Serbia, but mostly as personal doctors of the Belgrade pasha or Knez Miloš, i.e. his brother Jevrem in Šabac. In the fourth decade of the 19th century, the first military doctors set out, and the newly created four military district commands got their doctors. The Serbian Medical Association started the first medical journal, \"Serbian Archives\" in 1874. Josif Pancic is writing the first textbook in natural sciences, and Dr. Acim Medovic is writing the first textbook on forensic medicine. Before the First Serbian-Turkish War, the civilian ambulance numbered 69 doctors, 10 medical assistants, 26 pharmacists, and five pharmacy assistants, while the military ambulance had 19 doctors, five medical assistants, one pharmacist, and four pharmacy assistants. Health was initiated but also the establishment of the Ministry of Health and the higher education institution of the Medical Faculty in Belgrade. Guided by the oath, expertise, and experience, the doctors of that time made a significant effort to improve and develop medicine in Serbia in the 19th century. ","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47744503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-06-02DOI: 10.5937/sanamed17-36543
R. Dmitrović, B. Lazovic, Isidora Simonovic, A. Esquinas, Mersudin Mulić
{"title":"PRIMARY SPONTANEOUS PARTIAL PNEUMOTHORAX IN A PATIENT WITH COVID-19 PNEUMONIA. HAVE WE UNDERESTIMATED THIS COMPLICATION? A CASE REPORT","authors":"R. Dmitrović, B. Lazovic, Isidora Simonovic, A. Esquinas, Mersudin Mulić","doi":"10.5937/sanamed17-36543","DOIUrl":"https://doi.org/10.5937/sanamed17-36543","url":null,"abstract":"Introduction and case report: We described a case of primary spontaneous partial pneumothorax in a middle-aged man with COVID-19 pneumonia who presented with fever, loss of appetite, and malaise. Laboratory results revealed higher levels of inflammatory markers, as well as sterile urine and blood cultures. On admission, a chest X-ray revealed bilateral patchy consolidations in the lung parenchyma, as well as a left-sided partial pneumothorax. Throughout his hospitalization, the patient was closely examined by a thoracic surgeon, and a chest X-ray was taken on multiple occasions. There was spontaneous resorption of air from the pleural space. Conclusion: Pneumothorax is a rare but serious complication of the COVID-19 infection that has recently been documented in patients with no comorbidities, requiring various types of ventilatory support. The precise mechanism of primary spontaneous pneumothorax in COVID-19 infection is unknown, but it will undoubtedly pose a challenge to future researchers.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48492133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-06-02DOI: 10.5937/sanamed17-36698
Emina Hadžimuratović, Admir Hadžimuratović, D. Pokrajac, A. Selimović, Senad Muhasilović
{"title":"A PREDICTIVE VALUE OF EARLY CLINICAL PARAMETERS FOR ABNORMAL BRAIN MRI SCAN IN NEONATES TREATED WITH THERAPEUTIC HYPOTHERMIA","authors":"Emina Hadžimuratović, Admir Hadžimuratović, D. Pokrajac, A. Selimović, Senad Muhasilović","doi":"10.5937/sanamed17-36698","DOIUrl":"https://doi.org/10.5937/sanamed17-36698","url":null,"abstract":"Introduction: Brain MRI scans can predict neurodevelopmental outcomes in neonates treated with therapeutic hypothermia. It is a common clinical practice to perform brain MRI before discharge, but brain MRI scans performed at around four months of age have a better prognostic value for a long-term neurological outcome in asphyxiated neonates. \u0000Aim: To identify which of three selected clinical parameters (oral feeding ability, muscle tone, history of seizure) evaluated 10 days after therapeutic hypothermia could predict the primary outcome of an abnormal brain MRI. \u0000Methods: We reviewed the medical records of neonates ≥ 36 completed weeks of gestation consecutively treated with therapeutic hypothermia who underwent brain MRI. Clinical parameters on day 10 after therapeutic hypothermia were correlated with brain MRI findings in the first 7-14 days of life. Logic regression analysis was performed using all three covariates of the clinical status, with an abnormal MRI as the primary outcome. \u0000Results: Brain MRI was abnormal in 42 (51.85 %) neonates with the following distribution of brain injury patterns: abnormal signal in the basal nuclei in 6, an abnormal signal in the cortex in 16, an abnormal signal both in the cortex and basal nuclei in 20 neonates. Out of three analyzed clinical parameters, feeding difficulty (P < 0.001, OR 8.3, 95% CI 2.9 - 28.9) and a history of seizures (P < 0.001, OR 11.95, 95% CI 3 - 44.5) were significantly associated with an abnormal MRI. \u0000Conclusion: Neonates who were capable of full oral feeding by day 10 after therapeutic hypothermia and had no history of seizures were unlikely to have an abnormal MRI. This may be used in selective planning of pre-discharge MRI in asphyxiated neonates.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45535675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-06-02DOI: 10.5937/sanamed17-36526
S. Arslanagic, J. Karamehić
{"title":"SERUM C3 AND SERUM C4 COMPLEMENT IN PATIENTS WITH BURN TRAUMA AND CORRELATION WITH BURN INJURY SEVERITY","authors":"S. Arslanagic, J. Karamehić","doi":"10.5937/sanamed17-36526","DOIUrl":"https://doi.org/10.5937/sanamed17-36526","url":null,"abstract":"Introduction: Burns, depending on the degree of severity, induce a significant pathophysiological response in the body. The complement system participates in the body's defenses as well as in immune responses after burn-induced trauma. \u0000Objectives: The main objective of the study was to examine how burn severity affects serum C3 and serum C4 complement values; whether burn severity correlates with serum C3 and C4 complement, and establish the predictive value of the serum C3 complement and serum C4 complement for assessing the severity of the burn. \u0000 Patients and methods: According to the degree of TBSA, patients were classified into three groups: group with %TBSA<15% (30 patients), group with %TBSA >15% -25% (30 patients), and group with %TBSA > 25% to 40% (30 patients). According to the depth of burns, patients were classified into two groups partial-thickness burns (39 patients) and full-thickness burns (51 patients). We followed laboratory parameters: value serum C3 complement and serum C4 complement on the first and seventh day after burn trauma. \u0000Results: Serum C3 complement was significantly lower in patients with %TBSA>25%-40% and in the group with %TBSA>15%-25% compared to patients with %TBSA<15% on the first and seventh day after burn trauma. Serum C3 complement was significantly lower in patients with %TBSA >15%-25% compared to patients with %TBSA<15% on day one and day seven after burn trauma. Serum complement C4 was not significantly different between burn groups on the first and seventh day. Full-thickness burns have significantly lower levels of serum complement C3, compared to partial-thickness burns, on the 1st and 7th day. Full-thickness burns result in a decrease in serum C4 complement compared to partial-thickness burns on the 7th day after burn trauma, but this decrease is not significant. On the 1st day after burn trauma, we found a negative correlation between %TBSA with serum C3 complement. Serum C4 complement was not correlated with %TBSA on the day 1st. \u0000Conclusions: %TBSA and depth of burn result in a significant decrease in serum C3 complement but not serum C4 complement. There is a negative correlation of %TBSA and C3 complement but not serum C4 complement on the 1st day after burn trauma. Serum C3 complement is a significant predictor of burn severity. The predictory significance of the C4 complement is not statistically significant.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45057372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-01-22DOI: 10.24125/sanamed.v16i3.524
M. Sartelli
{"title":"LEVERAGING THE SYNERGY BETWEEN ANTIMICROBIAL STEWARDSHIP AND INFECTION PREVENTION AND CONTROL IN FIGHTING ANTIMICROBIAL RESISTANCE","authors":"M. Sartelli","doi":"10.24125/sanamed.v16i3.524","DOIUrl":"https://doi.org/10.24125/sanamed.v16i3.524","url":null,"abstract":"","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42939462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-01-22DOI: 10.24125/sanamed.v16i3.526
R. Dmitrović, B. Lazovic, Isidora Simonovic
{"title":"HIGH FLOW NASAL OXYGEN THERAPY (HFNO) IN OPPOSITION TO NON-INVASIVE MECHANICAL VENTILATION (NIV) ADVANTAGES, DISADVANTAGES AND THEIR USE IN COVID-19 INFECTION: BRIEF REVIEW","authors":"R. Dmitrović, B. Lazovic, Isidora Simonovic","doi":"10.24125/sanamed.v16i3.526","DOIUrl":"https://doi.org/10.24125/sanamed.v16i3.526","url":null,"abstract":": In the last few decades, different devices for oxygen application have become available, such as low flow systems, high flow systems (HFNO), and non-invasive ventilation (NIV). They are widely applicable and have many advantages as well as disadvantages. HFNO modalities decrease dead space, improve alveolar ventilation, and apply oxygen up to 60 l/min, delivering it humidified and heated opposite NIV, which increases anatomical dead space, main - tains adequate minute ventilation, and is used in more conditions than HFNO, etc. In our research, we included 12 articles. The study was conducted using literature published up from 2013 to July 2020. In our research we used following","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42687884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-01-22DOI: 10.24125/sanamed.v16i3.520
Yasemin Demir Yiğit, Ebral Yiğit
{"title":"THE EFFECT OF AGING ON THE DEMOGRAPHIC, INJURY AND HEALING PATTERNS OF BURN PATIENTS","authors":"Yasemin Demir Yiğit, Ebral Yiğit","doi":"10.24125/sanamed.v16i3.520","DOIUrl":"https://doi.org/10.24125/sanamed.v16i3.520","url":null,"abstract":"","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47914586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SanamedPub Date : 2022-01-22DOI: 10.24125/sanamed.v16i3.528
E. Jordanova, V. Samardžić, Gordana Pekovic-Perunicic, Jelena Tica-Jevtić, S. Simić-Ogrizović
{"title":"THE IMPORTANCE OF DETERMINING THE UROMODULIN SERUM CONCENTRATION IN DIABETES MELLITUS TYPE 2 PATIENTS","authors":"E. Jordanova, V. Samardžić, Gordana Pekovic-Perunicic, Jelena Tica-Jevtić, S. Simić-Ogrizović","doi":"10.24125/sanamed.v16i3.528","DOIUrl":"https://doi.org/10.24125/sanamed.v16i3.528","url":null,"abstract":"","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49318955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}