Sanamed最新文献

{"title":"EFFECT OF ANATOMO-TOPOGRAPHIC AND SONOGRAPHIC POLARITY OF THE THYROID NODULES ON THE THYROID MALIGNANCY BY EVALUATING ITS IMPRESSION ON THE RELATIONSHIP BETWEEN THE BETHESDA SYSTEM, TBSRTC, STRAIN ELASTOGRAPHY SCORE AND THE THYROID HISTOPATHOLOGY","authors":"D. Sengul, I. Sengul","doi":"10.24125/SANAMED.V14I1.325","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.325","url":null,"abstract":"Background: The goal is to evaluate the association between the topo-sonographic polarity of the thyroid nodules and the thyroid malignancy by analyzing its effect on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), score of Strain Elastography (SE) for thyroid as Tsukuba Elasticity Score (TES), and histopathologic assessment. Material and Methods: A preliminary single-center retrospective study was carried out by including the documents of 641 consecutive eligible patients, possessing 770 thyroid nodules which undergone neck ultrasonography (US), Doppler US, SE, and US-guided-fine needle aspiration (FNA) during April 2011 to April 2017. The stiffness had been measured by TES of SE. The ability of the prediction of the malignancy by the polarity of 770 thyroid nodules considering the association between; i) TBSRTC and histopathology and ii) TES and histopathology had been evaluated. Results: Of the 770 thyroid nodules evaluated, 408 (53.0%) were located at the superior pole (Pol 1) while 362 (47.0%) were at the inferior pole (Pol 0) with 0.9046 AUC and 0.8171 AUC for the association between TBSRTC and histopathology and 0.9280 AUC and 0.7888 AUC for the association between TES and histopathology, respectively. However, those difference were not significant for Pol 1, topographically. Conclusion : The topograghic and sonographic polarity of the thyroid nodules may not be useful for estimating the thyroid malignancy by using the association between TBSRTC and histopathology with TES and histopathology. However, the association with Pol 1, the superior thyroid pole, was stronger though the difference was not significant.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49137924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZOLEDRONIC ACID ADMINISTRATION ENHANCES FRACTURE HEALING IN THE OSTEOPOROTIC FRACTURES IN OVARIECTOMIZED RABBITS","authors":"G. Cansabuncu, N. Şahin, Y. Akalın, N. Çevik, G. Özkaya","doi":"10.24125/SANAMED.V14I1.288","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.288","url":null,"abstract":"Objectives:  To evaluate the radiological, histological and mechanical effects on osteoporotic fracture healing of single-dose zoledronic acid (ZA) applied to an animal model with an experimentally created osteoporotic bone fracture. Methods:  A total of 14 adult, female New Zealand rabbits, aged 5-6 months were used in the study. Bone mineral density (BMD) values were calculated from bone densitometry measurements and recorded. Bilateral ovariectomy was then applied to all the rabbits. At 10 weeks after ovariectomy, bone densitometry was again performed on all the animals and the BMD values were compared. Osteoporosis was accepted as having developed in animals determined with a reduction of 28% in BMD values. After the placement of a K-wire intramedullarly in the femurs of the rabbits, a closed fracture was created with the standard method. The animals were then randomly separated into 2 groups as the zoledronic acid group (ZAG) and the control group (CG). An infusion of 0.1mg/kg ZA was administered to the ZAG animals from the ear vein. With visualisation of bone union rabbits were sacrificed by decapitation. Radiological, mechanical and histological assesments were then applied. Results:  In the histological evaluation, the mean histological score was determined as 5.00 in the ZAG and 3.00 in the CG. The difference between the groups was found to be statistically significant (p<0.001). In the radiological evaluation, the mean score was 7.00 in the ZAG and 6.25 in the CG. Even though higher points were obtained by the ZAG in the inter-observer evaluations, the difference between the groups was not statistically significant (p=0.073). In the mechanical evaluation, the elasticity collapse in negative proportion to rigidity was measured as 2.91 mm in the ZAG and 3.96mm in the CG (p=0.686). The rigidity data of the ZAG were higher in the mechanical tests but the difference between the groups was not statistically significant (p=0.086). Conclusion:  As the results of the study showed that the ZAG had higher values than those of the CG in all the histological, mechanical and radiological evaluations, the application of a single dose of ZA can be considered to increase the healing of osteoporotic fractures.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42799699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FACTORS AFFECTING ANAESTHESIA PREFERENCES OF THE GRAVID WOMEN WHO ARE TO DELIVER BY CAESAREAN SECTION","authors":"Helin Sahinturk, S. Turhan, Selvi Ozlem Can, Ali Abbas Ylmaz, A. Uysalel","doi":"10.24125/SANAMED.V14I1.271","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.271","url":null,"abstract":"Objectives: In recent years, a significant increase has been observed in the prevalence of caesarean sections (CS). Although as in many other countries, CS rates in Turkey are higher than the targeted rate. This increase in the prevalence of CS also affects obstetric anaesthesia. In this study, we investigate the choice of anaesthesia among pregnant women who are scheduled for CS, as well as general anaesthesia and regional anaesthesia rates, the reasons for choosing general anaesthesia or regional anaesthesia, and the factors that affect their choices. Methods: A questionnaire consisting of 20 questions were applied to pregnant women applying for delivery by elective caesarean operation, between November 2011 to November 2012, in order to study the anaesthesia technique they prefer and the reason behind their preferences. The questionnaire was applied to pregnant women during the visit, on the day before the operation or while they were waiting in the waiting room before the CS procedure. Results : Our study revealed that age, gravida, previous type of delivery, previous anaesthesia experience, employment status, monthly income level, educational status, being given information about anaesthesia in advance, the source of information, and being diagnosed with panic disorder were all found to be influential in the decision of which type of anaesthesia to opt for. Conclusion : We have found out that the reason why pregnant women who have higher educational status, who work and have high level of monthly-income prefer regional anaesthesia method more depends on the fact that they have more information on anaesthesia method, they have more common use of the internet and the information they obtain from the people around them is not prejudiced against regional anaesthesia method. We believe that as the education levels rise in the future and the patient population becomes more aware, which will direct them to do more research, their preference rates will change.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43205575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALYSIS OF EFFECT OF THE ANTIDEPRESSANT SERTALINE ON THE LEGHT OF QT INTERVAL IN PATIENTS WITH DEPRESSION AND ALCOHOL DEPENDENCE","authors":"S. Stojanovic, Zlatan Stojanović, Gordana Macanović, N. Banjac, Želimir Erić","doi":"10.24125/SANAMED.V14I1.301","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.301","url":null,"abstract":"Introduction and Aim:  Depression in psychiatry covers a large area of mental pathology and it is one of the most complex problems of modern medicine with broad implications for the health of the individual and the society as a whole. Depression is also a frequent companion of alcohol addiction. The aim of this study was to investigate the effect of the antidepressant drug sertaline on the lenght of QT interval in depressed patients with alcohol dependence. Patients and methods : This research included male patients (older than 18 years of age) suffering from alcohol addiction, who were also diagnosed with depression, that is, depressive disorder,at the beginnig of hospitalisation, on the basis of DSM-IV (Diagnostic and statistical manual of mental disorders) criterion and positive Hamilton Rating Scale for Depression (HRSD). The study included 49 patients treated wit antidepressant sertaline for 20 days. In our study, the global QTc interval (12 leads) was determined automatically by applying ECG device of the producer and type \"Schiller Cardiovit AT-1\"which uses \"SCHILLER  ECG Measurement and Interpretation Software for Children and Adults ECGs\". Measured empirical values of data were statistically processed in SPSS 16.0 programme package for Windows. Methods of descriptive statistics and methods of statistic testing of hypotheses were used. Results : In our study, in spite of the vulnerability of patients due to the heart damage and the lyver dysfunction arising from alcohol consumption, as well as altered patients drugs metabolism, no elongation of QTc interval resulting from the application of sertaline was established (p=0.735). The average prolongation of QTc interval of 1.633 ms was observed (95% CI =8.005 ms, 11.270 ms). Conclusion :Our study does not indicate that the antidepressant drug sertaline has a statistically significant effect on the prolongation of the QT interval of depressed patients with alcohol dependence.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46744005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PHANTOM TUMOR OF THE LUNG IN PATIENT WITH PNEUMONIA","authors":"Mersudin Mulić, B. Lazovic, Džemail Detanac, Dzenana A. Detanac, R. Milić, V. Žugić","doi":"10.24125/SANAMED.V14I1.323","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.323","url":null,"abstract":"Introduction: Localized interlobar effusions in congestive heart failure (phantom or vanishing lung tumor/s) are infrequent, but widely recognized entities. Case report: A 80-years-old woman affected by progressive dyspnea over the previous three months, with productive cough. She was treated hypertension and had a pace maker implanted due to bradycardia. Chest X ray has shown right side pneumonia with high positive inflammatory markers.  After resolution of pneumonia, phantom tumor of the lung was revealed, which disappear with intensive loop diuretics. Conclusions: The diagnosis of the phantom tumor ought to be pondered as a possibility in any patient with congestive heart failure and lung mass. The patient at hand featured no prior history of congestive heart failure, hence indicating that phantom tumor may occur in non-chronic heart failure patients. Albeid the reliable diagnosis of the phantom tumor through the utilization of imaging modalities in patients without congestive heart failure can be rather challenging, such possibility must be considered in a patient with a lung mass in the major fissure of the lungs. Due to accelerated expansion of the geriatric population and subsequent spread of the congestive heart failure, a rise in the incidence of vanishing tumors of the lung may be anticipated.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47459981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS PREDICTION OF RENAL FAILURE WITH ITS INDICES FEASIBLE WITH PRESENCE OF HISTOPATHOLOGIC EVIDENCE FOR GASTRIC INTESTINAL METAPLASIA ?","authors":"D. Sengul","doi":"10.24125/SANAMED.V14I1.322","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.322","url":null,"abstract":"Objectives: Gastric intestinal metaplasia have traditionally been associated with gastric adenocarcinoma. Gastric intestinal metaplasia is usually related to the Helicobacter pylori infection, older ages, smoking history, consumption of strong spicy foods, socioeconomic status and presence of IL10-592 C/A. The purpose of the present research study was to evaluate the simple laboratory parameters in subjects with gastric intestinal metaplasia Findings: From May 2018 and October 2018, a total of 541, 281 male and 260 female, consecutive cases with gastric intestinal metaplasia with the mean age of 58.5±15 years had been enrolled retrospectively with exclusion of the cases with a severe underlying disease, including a gastric cancer and gastric resection. The gastroscopy with the antral biopsy had been performed for all the cases and the biopsy samples had been evaluated for the presence of gastric intestinal metaplasia by Hematoxylin and Eosin and Helicobacter pylori status by Giemsa.The chi-squared test and independent t test were used for comparison. The mean serum urea level detected as 34.2.±16.1 mg/dL in the gastric intestinal metaplasia and 31.2±13.1 mg/dL in the control (95% CI from 32,3 to 34,6; p =0.013), while the mean serum creatinin level 0.84±0.28 mg/dL in the gastric intestinal metaplasia and 0.80±0.26 mg/dL in the control (95% CI from 0,80 to 0,85; p =0.042).  Gastric intestinal metaplasia was detected mostly in elderly and male, regarding the multiple logistic regression ( p <0.001). Conclusion: The serum urea and creatinin levels may serve as a simple clinical tool to predict the cases patients at risk for gastric intestinal metaplasia.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44888104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EPIDEMIOLOGY OF OVERWEIGHT AND OBESITY OF TRAITORS OF THE MULTIMODAL FREIGHT MANAGEMENT OFFICE OF THE CITY PROVINCE OF KINSHASA","authors":"Kusuayi Mabele Godefroid, Constant Nkiama Ekisawa, Jolie Bongo Nzeloka, C. Delecluse, F. L. Bompeka","doi":"10.24125/SANAMED.V14I1.277","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.277","url":null,"abstract":"Objective: To determine the prevalence of overweight and obesity in the workplace.  Methods: We conducted a cross-sectional study with 210 workers of which 119 male (56.7%) and 91 female (43.3%) selected in a simple random manner in a company in the city of Kinshasa province between November 2013 to January 2014. Overweight was determined by workers with a body mass index between 25 and 29.9 kg / m 2 and obesity by those with a body mass index ≥ 30 kg / m 2 .  Results: This study found a prevalence of 23.8% of overweight workers and 48.1% of workers suffering from obesity with predominance in women (65.5% in men vs. 80.2% in women, p <0.014). The frequency of risk factors associated with obesity increased with the increase in weight status of BMI (p <0.001).  Conclusion: Obesity is a common pathology in the workplace and hypertension is the main modifiable risk factor. Sedentarity is the main determinant of overweight and obesity. Obesity is a public health problem in the workplace in the city of Kinshasa because of the command and collaboration frameworks are most affected.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44831982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE INFLUENCE OF CHRONIC STRESS ON HEALTH AND COPING MECHANISMS","authors":"M. Bosnjak, Milota Dobovski-Poslon, Željko Bibić, Kristina Bošnjak","doi":"10.24125/SANAMED.V14I1.293","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.293","url":null,"abstract":"Stress represents a negative life experience, closely followed by physiological, cognitive, emotional, and behavioral changes that focus on changing the event or adapting to its effects. Any situation or occurrence that requires adaptation can be experienced as a stress, even positive situations and circumstances may be stressful, whether they come from the outside world, or the sources of stress is internal. While acute stress does not necessarily have a negative effect, if it lasts for a long time, or is frequently repeated, it becomes chronic, and can cause various serious disorders. During chronic stress, there is an exhaustion of the body's capacity for an adequate reaction, which can lead to long-lasting immunological dysfunction, which significantly impairs health and quality of life. According to the WHO (2017), stress is one of the causes of even 60% known diseases, and in a number of mental disorders a direct connection with stress has been reported: in acute stress reactions, \"posttraumatic stress disorder\", adjustment disorders and other reactions to severe stress. In addition, in all categories of mental disorders (ICD-10), the stressful situation or event plays a significant role in occurrence of the symptoms. A particular category of stress-related disorders are psychosomatic disorders. These are functional disorders in which there is no pathoanatomic substrate. In contrast to these, psychosomatic diseases are the type of illness in which there are structural changes of tissues and organs, the etiology of which is based on chronic stress, in addition to a number of other factors (Adamovic, 1983) and which occur when there is a biological predisposition. The paper presents the mechanism of development of these diseases and some of the ways of coping with stress.  According to the DSM-V, psychosomatic diseases are divided into skin diseases, gastrointestinal diseases, respiratory diseases, heart and blood vessel diseases, disorders of endocrine glands, rheumatoid diseases, gynecological diseases and others. In order to overcome stress and preserve health, psychological strategies for coping with stress play an important role. Multiple strategies are used, which include various stress control techniques: relaxation techniques, meditation methods, and assertive training, biofeedback and stress inoculation techniques. Successful mastering of coping stressful situations, constructive problem solving in life crisis, relaxation techniques and contributions to better adaptation to unexpected changes in life are of key importance for both mental and physical health.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45258898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LIP PITS ABSCESS: ISOLATED CONGENITAL MIDLINE UPPER LIP SINUS","authors":"M. Izzuddin, A. Ishak, N. Basiron","doi":"10.24125/SANAMED.V14I1.303","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.303","url":null,"abstract":"Congenital midline upper lip sinuses or fistulas are exceptionally uncommon condition following abnormal fusion of embryologic structures. Here, we report a case of congenital upper lip sinus type I presented as upper vestibular fold abscess in a seven year old boy.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44440583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE OXYBUTYNIN ABUSE IN ADOLESCENT CASE","authors":"O. Kardas, Burcu Kardaş","doi":"10.24125/SANAMED.V14I1.300","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I1.300","url":null,"abstract":"Oxybutynin is one of the most commonly prescribed drugs in overactive bladder treatment. Because of its lipophilic structure, it crosses the blood-brain barrier and causes cognitive side effects in the central nervous system. Abuse of the drug is due to its hallucinogenic effect. In terms of substance use disorder, adolescents are one of the groups at risk. In addition to well-known addictive substances, drugs which have sedative, anticholinergic-antimuscarinic, stimulant properties and prescribed for any treatment also can be abused in adolescents with substance abuse. In this article, it is aimed to raise awareness of physicians and health workers about oxybutynin abuse because of the pharmacodynamic characteristics of the drug and its effects on the central nervous system. The health professionals should therefore prescribe this drug with more attention and follow-up those patients.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44401285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}