eJournal of Oral Maxillofacial Research最新文献

{"title":"Osseointegration Aspects of Implants at the Bone Reconstruction Site by a Novel Porous Titanium Scaffold.","authors":"Kazuya Doi, Reiko Kobatake, Yusuke Makihara, Yoshifumi Oki, Hanako Umehara, Takayasu Kubo, Kazuhiro Tsuga","doi":"10.5037/jomr.2021.12304","DOIUrl":"10.5037/jomr.2021.12304","url":null,"abstract":"<p><strong>Objectives: </strong>Porous titanium is used for the reconstruction of large bone defects due to its excellent mechanical strength. The quality of osseointegration of implants placed in bone reconstructed with porous titanium is unknown. The purpose of this <i>in vivo</i> study was to evaluate the osseointegration of implants at sites reconstructed using porous titanium.</p><p><strong>Material and methods: </strong>Hollow porous titanium (Ti) (outer-diameter 6 mm, inner-diameter 2 mm, length 4 mm, 85% porosity) and similar-sized porous hydroxyapatite (porous HA: 75% porosity) samples were prepared and implanted in 6 New Zealand white rabbit femurs. Four weeks later, an implant bed was created to receive a Ti implant (diameter 2 mm, length 4 mm). An implant placed at a pristine bone site served as the control. Four weeks later, histological and histomorphometric evaluations of the test and control sites were conducted.</p><p><strong>Results: </strong>Osseointegration was observed in all groups. There was no significant difference in the bone formation ratio and bone-implant contact (BIC) ratio across all groups for the whole area. At the cancellous bone area of the bone defect, superior bone formation ratio and BIC ratio were observed with porous Ti and porous HA compared to the control (bone formation ratio: control 1.8 [SD 3]%, HA 23 [SD 3]%, Ti 23.6 [SD 5]%; BIC ratio: control 5.4 [SD 5.3]%, HA 28.9 [SD 10.7]%, Ti 41.6 [SD 14]%). Porous Ti demonstrated good osteoconduction and osseointegration abilities, similar to porous HA.</p><p><strong>Conclusions: </strong>To our knowledge, this is the first report of implant treatment after preliminary bone reconstruction using a titanium biomaterial. Porous titanium is a suitable material for bone reconstruction before implant treatment in load-bearing areas that allow subsequent prosthetic treatment.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"12 3","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/45/b6/jomr-12-e4.PMC8577583.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39623567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Reliability and Influence of Body Position on Acoustic Pharyngometry and Rhinometry Outcomes.","authors":"Sofie Wilkens Knappe,&nbsp;Liselotte Sonnesen","doi":"10.5037/jomr.2020.11401","DOIUrl":"https://doi.org/10.5037/jomr.2020.11401","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this cross sectional study was to analyze the method error and reliability in acoustic pharyngometry and rhinometry and to analyze the difference between standing and sitting position in acoustic pharyngometry and rhinometry.</p><p><strong>Material and methods: </strong>The sample comprised 38 healthy subjects (11 men and 27 women) as part of a control group in another study. The subjects underwent repeated measures of acoustic pharyngometry and rhinometry in standing and sitting position. Upper airway dimensions in terms of volume, minimum cross-sectional areas (MCA) and distances were evaluated using the Eccovision^® Acoustic Pharyngometer and Rhinometer. Method error and reliability were analyzed using paired t-test, Dahlberg's formula and the Houston reliability coefficient, and differences between body positions were analyzed using paired t-test.</p><p><strong>Results: </strong>There was no systematic error in the repeated measures except for the distance to MCA in the left nostril in sitting position (P = 0.041). The method error for the pharyngometry ranged between 0.001 to 0.164 cm/cm²/cm³ and the reliabity was 0.99. The method error for rhinometry ranged between 0.001 to 0.37 cm/cm²/cm³ and the reliability between 0.99 to 1. Difference between standing and sitting position was found only in the pharyngeal airway in terms of volume (P = 0.025) and mean area (P = 0.009) with smaller airway in sitting position.</p><p><strong>Conclusions: </strong>The results indicate that acoustic pharyngometry and rhinometry are reliable methods to perform repeated measures of the upper airway dimensions especially in the standing mirror position. It may be essential to perform the measures with the patient positioned in the same body position each time.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"11 4","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c5/1b/jomr-11-e1.PMC7875104.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10639780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Study of Surface Modification Treatment for Porous Titanium.","authors":"Reiko Kobatake, Kazuya Doi, Yoshifumi Oki, Yusuke Makihara, Hanako Umehara, Takayasu Kubo, Kazuhiro Tsuga","doi":"10.5037/jomr.2020.11205","DOIUrl":"10.5037/jomr.2020.11205","url":null,"abstract":"<p><strong>Objectives: </strong>This study was to investigate suitable surface treatment methods for porous titanium by <i>ex vivo</i> study of material properties and calcium phosphate deposition in simulated body fluid.</p><p><strong>Material and methods: </strong>Porous titanium with acid (H₂SO₄ and HCl mixed acid) or alkali (NaOH) treatment was prepared. The surfaces were observed, and the weight change ratio (after and before surface treatment) and compression strength were measured. To investigate the apatite formation ability, each sample was immersed in simulated body fluid (SBF). Surface observations were performed, and the weight change ratio (before/after immersing SBF) and calcification (by alizarin red staining) were measured.</p><p><strong>Results: </strong>The acid group showed a martensitic micro-scale rough structure and the weight and mechanical strength greatly decreased compared to the other groups. The alkali group exhibited a nano-scale roughness structure with similar weight and mechanical strength. Following immersion in SBF, an apatite-like crystal layer in the alkali group was observed. The weight of all samples increased. The change in weight of the samples in the alkali, acid, and control groups were significantly different, showing the following trend: alkali group (1.6%) > acid group (1.2%) > control group (0.8%). Calcium precipitation values were higher in the samples from alkali group than in those from the acid and control groups.</p><p><strong>Conclusions: </strong>Alkali treatment was found to be a suitable surface modification method for porous titanium, resulting in good mechanical strength and apatite formation ability in simulated body fluid.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"11 2","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/ef/jomr-11-e5.PMC7393927.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38243621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Botulinum Toxin A in the Management of Trigeminal Neuralgia: a Systematic Literature Review.","authors":"Anton Rubis, Gintaras Juodzbalys","doi":"10.5037/jomr.2020.11202","DOIUrl":"10.5037/jomr.2020.11202","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this article is to systematically review the use, efficacy, differences between botulinum toxin type A doses and side effects of botulinum toxin type A therapy in patients with trigeminal neuralgia.</p><p><strong>Material and methods: </strong>The search for the performed reviews was done in PubMed and Cochrane library in English language from January 2010 up to February 2020. Inclusion criteria: full-text studies in English language, in which visual assessment scale (VAS) was present, in which patients with trigeminal neuralgia (TN) were participated and the comparison between botulinum toxin type A (BT-A) and saline was done.</p><p><strong>Results: </strong>The review included 4 randomized, double-blind, placebo-controlled trials with 8 to 12 weeks follow-up to observe changes in VAS and in frequency of TN attacks, differences between dosages of BT-A in therapy and side effects. Mean VAS of BT-A group decreased by approximately 68% and of palcebo group decreased by approximately 21.6% after the therapy. Mean frequency of TN attacks in 3 studies of BT-A group decreased by 85%, while in palcebo by only 15.9%.</p><p><strong>Conclusions: </strong>Botulinum toxin type A injection therapy is a safe and effective method in management of trigeminal neuralgia. No differences between dosages of botulinum toxin type A were found. Maximum efficacy was noticed between 6 weeks and 3 months after the procedure. Side effects were mostly facial asymmetry after injection, headaches, haematoma, which disappeared in one week.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"11 2","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/ba/jomr-11-e2.PMC7393930.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38244615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular and Cellular Aspects of Socket Healing in the Absence and Presence of Graft Materials and Autologous Platelet Concentrates: a Focused Review.","authors":"Pedro de Sousa Gomes,&nbsp;Povilas Daugela,&nbsp;Lukas Poskevicius,&nbsp;Lorena Mariano,&nbsp;Maria Helena Fernandes","doi":"10.5037/jomr.2019.10302","DOIUrl":"https://doi.org/10.5037/jomr.2019.10302","url":null,"abstract":"<p><strong>Objectives: </strong>The present manuscript aims to critically detail the physiologic process of socket healing, in the absence or presence of grafting materials or platelet concentrates, addressing the associated molecular and cellular events that culminate in the restoration of the lost tissue architecture and functionality.</p><p><strong>Material and methods: </strong>An electronic search in the National Library of Medicine database MEDLINE through its online site PubMed and Web of Science from inception until May 2019 was conducted to identify articles concerning physiologic process of socket healing, in the absence or presence of grafting materials or platelet concentrates. The search was restricted to English language articles without time restriction. Additionally, a hand search was carried out in oral surgery, periodontology and dental implants related journals.</p><p><strong>Results: </strong>In total, 122 literature sources were obtained and reviewed. The detailed biological events, at the molecular and cellular level, that occur in the alveolus after tooth extraction and socket healing process modulated by grafting materials or autologous platelet concentrates were presented as two entities.</p><p><strong>Conclusions: </strong>Tooth extraction initiates a convoluted set of orderly biological events in the alveolus, aiming wound closure and socket healing. The healing process comprises a wide range of events, regulated by the interplay of cytokines, chemokines and growth factors that determine cellular recruitment, proliferation and differentiation in the healing milieu, in a space- and time-dependent choreographic interplay. Additionally, the healing process may further be modulated by the implantation of grafting materials or autologous platelet concentrates within the tooth socket, aiming to enhance the regenerative outcome.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"10 3","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2019-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71434923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Tooth Derived Bone Graft Materials in Sinus Augmentation Procedures: a Systematic Review.","authors":"Eliyahu Shavit,&nbsp;Ilana Shavit,&nbsp;Daniel Pinchasov,&nbsp;David Shavit,&nbsp;Ginnady Pinchasov,&nbsp;Gintaras Juodzbalys","doi":"10.5037/jomr.2019.10201","DOIUrl":"https://doi.org/10.5037/jomr.2019.10201","url":null,"abstract":"<p><strong>Objectives: </strong>The goal of this systematic review was to assess the current literature about sinus augmentation procedure using different types of tooth derived bone graft materials, thorough analysing the outcomes of sinus grafting with tooth grafts compared to sinus grafting with xenografts, allografts and alloplasts by radiography and histomorphometry.</p><p><strong>Material and methods: </strong>An electronic search in the MEDLINE (NCBI PubMed and PubMed Central) database was conducted to identify articles concerning application of tooth bone grafts in sinus augmentation. The search was restricted to English language articles published in the last 10 years (December 2009 to March 2019).</p><p><strong>Results: </strong>In total, 21 articles were found, out of which 7 met the inclusion criteria and were included in the final synthesis. According to the type of diagnostic tool, data about graft material outcome in sinus was extracted, and included the residual alveolar height, augmented graft height, resorption height as seen in panoramic radiography and histomorphometric analysis of new bone formation and residual graft material.</p><p><strong>Conclusions: </strong>Within the limitations of our review, we suggest that tooth derived graft materials are as successful as xenografts, allografts and alloplasts in sinus augmentation procedures according to the radiographic and histomorphometric showings. Additional wider research should be conducted in order to determine whether tooth derived graft materials are superior to the currently used materials.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"10 2","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5037/jomr.2019.10201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short Dental Implants (6 mm) Versus Standard Dental Implants (10 mm) Supporting Single Crowns in the Posterior Maxilla and/or Mandible: 2-Year Results from a Prospective Cohort Comparative Trial.","authors":"Luigi Svezia,&nbsp;Filippo Casotto","doi":"10.5037/jomr.2018.9304","DOIUrl":"10.5037/jomr.2018.9304","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of present study was to compare short (6 mm) with longer implants with the same surface use in the posterior maxilla and/or mandible.</p><p><strong>Material and methods: </strong>A total of 110 implants of 6 or 10 mm in length were placed with an internal hex (n = 60) and with a conical connection (n = 50) but the same material, surface and design, supporting single crowns in the posterior maxilla and/or mandible. Outcomes measured were implant survival and marginal bone level changes up to 24 months after loading.</p><p><strong>Results: </strong>Final group consisted of 105 implants: 6 mm (n = 58) and 10 mm (n = 47). Success rate after 24 months was similar between treatment groups (98.3% vs. 100%; P = 0.361). Failure rates of the short implants in mandible (1/18, 5.6%) and in maxilla (0/40, 0%) were also not significantly different (P = 0.133). Success rate after 2 years was similar between internal hex vs. conical connection implants (100% vs. 97.7%; P = 0.233). Subjects lost statistically significant marginal peri-implant bone in both groups, but without differences (6 mm group: 0.38 mm [95% CI = 0.09 to 0.67] vs. 10 mm group: 0.43 mm [95% CI = 0.15 to 0.61]; P = 0.465 at 24 months), in relation also to type of implant (internal hex vs. conical, P = 0.428 at 24 months) or operator (P = 0.875 at 24 months).</p><p><strong>Conclusions: </strong>Short implants may be successful in the posterior areas during the first 24 months of loading, with similar outcomes to 10 mm long implants, supporting their use as a valid option in selected cases. However, larger and longer follow-ups of 5 years or more are needed.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"9 3","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5037/jomr.2018.9304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36666420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Autologous Stem Cells for the Regeneration of Periodontal Defects in Animal Studies: a Systematic Review and Meta-Analysis.","authors":"Algimantas Gaubys, Valdas Papeckys, Mindaugas Pranskunas","doi":"10.5037/jomr.2018.9203","DOIUrl":"10.5037/jomr.2018.9203","url":null,"abstract":"<p><strong>Objectives: </strong>To overview preclinical animal trials and quantify the effect size that stem cell therapy has on the regeneration of periodontal tissue complex.</p><p><strong>Material and methods: </strong>A systematic MEDLINE (PubMed) online library search was conducted for preclinical animal studies <i><i>in vivo</i></i> , using autologous periodontal ligament, dental pulp, cementum, alveolar periosteal, gingival margin or adipose stem cell types for periodontal tissue complex regeneration purposes. Studies had to be published between 2007.09.01 and 2017.09.01 in the English language.</p><p><strong>Results: </strong>Online library search yielded 2099 results. After the title, abstract and full-text screening ten studies fit inclusion criteria and were pooled into meta-analysis. Overall the stem cell regenerative therapy had a statistically significant positive influence on the periodontal tissue regeneration when compared to the control groups. The biggest influence was made to the regeneration of cementum (standardised mean difference [SMD] 2.25 [95% confidence interval (CI) = 1.31 to 3.2]) while the smallest influence was made to the alveolar bone (SMD 1.47 [95% CI = 0.7 to 2.25]) the effect size for periodontal ligament regeneration was (SMD 1.8 [95% CI = 1 to 2.59]). Subgroup analysis showed statistically significant (P < 0.05) differences between different cell types in the alveolar bone and cementum regeneration groups and in alveolar bone group in relation to scaffold materials.</p><p><strong>Conclusions: </strong>Stem cell therapy has a positive impact on periodontal tissue complex regeneration. Such therapy has the biggest influence on cementum regeneration meanwhile alveolar bone regeneration is influenced by the least amount. However more and less diverse preclinical studies are needed to have a greater statistical power in future meta-analyses.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"9 2","pages":"e3"},"PeriodicalIF":0.0,"publicationDate":"2018-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/80/jomr-09-e3.PMC6090251.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36403522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study.","authors":"Renzo Guarnieri, Luigi Stefanelli, Francesca De Angelis, Francesca Mencio, Giorgio Pompa, Stefano Di Carlo","doi":"10.5037/jomr.2017.8305","DOIUrl":"10.5037/jomr.2017.8305","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous healing.</p><p><strong>Material and methods: </strong>Thirty patients were enrolled in the present study and underwent single-tooth extraction in the premolar/molar areas. Ten sites were grafted with porcine-derived bone covered by collagen membrane, 10 covered by porcine-derived collagen membrane alone, and 10 underwent natural spontaneous healing. Vertical and horizontal bone changes after 3-month were evaluated at implant placement.</p><p><strong>Results: </strong>The vertical and horizontal bone changes at the extraction sockets treated with collagen membrane alone (vertical: -0.55 [SD 0.11] mm, and horizontal: -1.21 [SD 0.69] mm) and collagen membrane plus porcine-derived bone (vertical: -0.37 [SD 0.7] mm, and horizontal: -0.91 [SD 0.53] mm) were found significantly lower (P < 0.001), when compared to non-grafted sockets (vertical: -2.09 [SD 0.19] mm, and horizontal: -3.96 [SD 0.87] mm).In type 1 extraction sockets, in premolar sites, and in presence of vestibular bone thicknesses ≥ 1.5 mm, the use of collagen membrane alone revealed similar outcomes to those with additional graft material.</p><p><strong>Conclusions: </strong>At the re-entry surgery, extraction sockets grafted with porcine-derived bone and covered by collagen membrane, and extraction sockets covered by porcine-derived collagen membrane alone, showed significantly lower vertical and horizontal bone changes, compared to extraction sockets sites underwent natural spontaneous healing. However, a complete prevention of remodelling is not achievable, irrespective of the technique used.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"8 3","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/4c/jomr-08-e5.PMC5676315.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35613946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Nasoalveolar Molding and Surgical, Aesthetic, Functional and Socioeconomic Outcomes Following Primary Repair Surgery: a Systematic Review.","authors":"Sophie Maillard, Jean-Marc Retrouvey, Mairaj K Ahmed, Peter J Taub","doi":"10.5037/jomr.2017.8302","DOIUrl":"10.5037/jomr.2017.8302","url":null,"abstract":"<p><strong>Objectives: </strong>The authors performed a systematic review to evaluate the potential beneficial effects of the nasoalveolar molding appliance on nonsyndromic unilateral clefts of the lip and/or palate prior to primary lip repair.</p><p><strong>Material and methods: </strong>A literature search was performed using three electronic databases (PubMed, Embase, Web of Science) and three journals (\"Cleft Palate-Craniofacial Journal\", \"Plastic and Reconstructive Surgery Journal\" and \"American Journal of Orthodontics and Dentofacial Orthopaedic\") from January 1980 to April 2017. Data extraction was performed with tables treating different subjects: surgical, aesthetical, functional, socio-economical effects of nasoalveolar molding (NAM) appliances and the evolution of NAM appliances, especially three-dimensional technology.</p><p><strong>Results: </strong>Of the 145 articles retrieved in the literature surveys, 28 were qualified for the final analysis and 20 studies were excluded because of their small sample size (less than 10 patients) and/or too long follow-up (exceeded 18 months). Four randomized controlled trials were available. Although literature allowed discussing the short-term benefits of NAM appliance and the three-dimensional technology, scientific evidence is lacking.</p><p><strong>Conclusions: </strong>Based on the results, nasoalveolar molding appliances have positive surgical, aesthetical, functional and socio-economical effects on unilateral clefts of the lip and/or palate treatment before the primary repair surgeries. Three-dimensional technology results in a more efficient and predictable nasoalveolar molding appliance treatment. However, nasoalveolar molding appliance effect in a short term remains unclear with the available literature. Further studies that integrate three-dimensional technology in a large scale are still needed.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"8 3","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/cd/jomr-08-e2.PMC5676312.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35613949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}