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Correction to “Confidential and non-confidential drug rebates in Switzerland, 2013–2023: empirical analysis of drug rebates, trends over time and re-evaluations” [The Lancet Regional Health—Europe, volume 46, November 2024, 101094]
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-11 DOI: 10.1016/j.lanepe.2025.101219
Noah Rohner, Cascal Herrle, Luca Locher, Kerstin N. Vokinger
{"title":"Correction to “Confidential and non-confidential drug rebates in Switzerland, 2013–2023: empirical analysis of drug rebates, trends over time and re-evaluations” [The Lancet Regional Health—Europe, volume 46, November 2024, 101094]","authors":"Noah Rohner, Cascal Herrle, Luca Locher, Kerstin N. Vokinger","doi":"10.1016/j.lanepe.2025.101219","DOIUrl":"10.1016/j.lanepe.2025.101219","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"50 ","pages":"Article 101219"},"PeriodicalIF":13.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007–2023: a systematic review and secondary analysis
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-10 DOI: 10.1016/j.lanepe.2025.101231
Paolo Cattaneo , Elena Salvador , Mattia Manica , Luisa Barzon , Concetta Castilletti , Francesco Di Gennaro , Ralph Huits , Stefano Merler , Piero Poletti , Flavia Riccardo , Annalisa Saracino , Francesco Segala , Lorenzo Zammarchi , Dora Buonfrate , Federico Gobbi
{"title":"Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007–2023: a systematic review and secondary analysis","authors":"Paolo Cattaneo ,&nbsp;Elena Salvador ,&nbsp;Mattia Manica ,&nbsp;Luisa Barzon ,&nbsp;Concetta Castilletti ,&nbsp;Francesco Di Gennaro ,&nbsp;Ralph Huits ,&nbsp;Stefano Merler ,&nbsp;Piero Poletti ,&nbsp;Flavia Riccardo ,&nbsp;Annalisa Saracino ,&nbsp;Francesco Segala ,&nbsp;Lorenzo Zammarchi ,&nbsp;Dora Buonfrate ,&nbsp;Federico Gobbi","doi":"10.1016/j.lanepe.2025.101231","DOIUrl":"10.1016/j.lanepe.2025.101231","url":null,"abstract":"<div><h3>Background</h3><div>Local transmission of dengue, chikungunya, and Zika infection is an emerging public health threat in Europe. Monitoring the epidemiological trends can help define the intervention strategy. The aim of this work was to analyse epidemiological characteristics of autochthonous transmission of <em>Aedes</em>-borne arboviruses in Europe.</div></div><div><h3>Methods</h3><div>A systematic review of the literature published from January 1, 2007, to January 31, 2024, reporting autochthonous cases of dengue, chikungunya, and Zika detected in Europe was performed. We searched MEDLINE, EMBASE, and the ECDC reports. Descriptive statistics and a secondary analysis were used to summarize the epidemiological characteristics of local transmission events (LTEs), explore potential temporal trends and identify relevant associations between epidemiological variables. Time intervals between key events were analysed to identify potential delays in LTE identification and intervention.</div></div><div><h3>Findings</h3><div>A total of 59 studies were included, describing 56 LTEs. The frequency of LTEs increased over time, with an average of 1.25 (95% CI: 1.17–1.35) times increment every year. While the highest number of dengue LTEs was reported in France (N = 37), Italy faced the largest number of cases detected in an LTE (N = 41). Considering all the arboviral LTEs, the median time between the symptom onset of the primary case and the diagnosis of the index case (“outbreak detection”) was 35.5 days (range 23.0–76.0). Only for chikungunya, higher delays correlated with higher cumulative number of cases detected per LTE, though this may be biased due to the low sample size.</div></div><div><h3>Interpretation</h3><div>We have observed a gradual increase of <em>Aedes</em>-borne arboviral LTEs in Europe over time, and a considerable delay in outbreak detection. Improving the timeliness of LTE identification is essential.</div></div><div><h3>Funding</h3><div>This work was partly funded by the <span>Italian Ministry of Health</span> (Ricerca corrente) and by the <span>European Union</span> (Next Generation EU, Missione 4 Componente 1 CUP <span><span>H93C22000640007</span></span>).</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101231"},"PeriodicalIF":13.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smartphone use and mental health: going beyond school restriction policies
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-08 DOI: 10.1016/j.lanepe.2025.101237
Helen A. Weiss , Chris Bonell
{"title":"Smartphone use and mental health: going beyond school restriction policies","authors":"Helen A. Weiss ,&nbsp;Chris Bonell","doi":"10.1016/j.lanepe.2025.101237","DOIUrl":"10.1016/j.lanepe.2025.101237","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101237"},"PeriodicalIF":13.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing transparency and validity in psychosocial intervention research for migrant populations – authors' reply
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-08 DOI: 10.1016/j.lanepe.2025.101236
Giulia Turrini, Federico Tedeschi, Corrado Barbui
{"title":"Enhancing transparency and validity in psychosocial intervention research for migrant populations – authors' reply","authors":"Giulia Turrini,&nbsp;Federico Tedeschi,&nbsp;Corrado Barbui","doi":"10.1016/j.lanepe.2025.101236","DOIUrl":"10.1016/j.lanepe.2025.101236","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"50 ","pages":"Article 101236"},"PeriodicalIF":13.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing transparency and validity in psychosocial intervention research for migrant populations
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-08 DOI: 10.1016/j.lanepe.2025.101235
Yongjia Zhou , Qingyong Zheng , Caihua Xu , Jinhui Tian
{"title":"Enhancing transparency and validity in psychosocial intervention research for migrant populations","authors":"Yongjia Zhou ,&nbsp;Qingyong Zheng ,&nbsp;Caihua Xu ,&nbsp;Jinhui Tian","doi":"10.1016/j.lanepe.2025.101235","DOIUrl":"10.1016/j.lanepe.2025.101235","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"50 ","pages":"Article 101235"},"PeriodicalIF":13.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined use of respiratory multiplex PCR and procalcitonin to reduce antibiotic exposure in sickle-cell adult patients with acute chest syndrome (The ANTIBIO-STA study): a randomised, controlled, open-label trial
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-07 DOI: 10.1016/j.lanepe.2025.101234
Alexandre Sabaté-Elabbadi , Armand Mekontso-Dessap , François Lionnet , Aline Santin , Charlotte Verdet , Paul-Louis Woerther , Julien Lopinto , Matthieu Turpin , Alexandra Rousseau , Romane Lacoste-Badie , Keyvan Razazi , Guillaume Voiriot , Muriel Fartoukh
{"title":"Combined use of respiratory multiplex PCR and procalcitonin to reduce antibiotic exposure in sickle-cell adult patients with acute chest syndrome (The ANTIBIO-STA study): a randomised, controlled, open-label trial","authors":"Alexandre Sabaté-Elabbadi ,&nbsp;Armand Mekontso-Dessap ,&nbsp;François Lionnet ,&nbsp;Aline Santin ,&nbsp;Charlotte Verdet ,&nbsp;Paul-Louis Woerther ,&nbsp;Julien Lopinto ,&nbsp;Matthieu Turpin ,&nbsp;Alexandra Rousseau ,&nbsp;Romane Lacoste-Badie ,&nbsp;Keyvan Razazi ,&nbsp;Guillaume Voiriot ,&nbsp;Muriel Fartoukh","doi":"10.1016/j.lanepe.2025.101234","DOIUrl":"10.1016/j.lanepe.2025.101234","url":null,"abstract":"<div><h3>Background</h3><div>Respiratory infection may account for 30% of acute chest syndrome (ACS) aetiologies. However, antimicrobials are routinely prescribed, and de-escalation and/or discontinuation are challenging. Multiplex Polymerase Chain Reaction (mPCR) with an enlarged respiratory panel might support antimicrobial stewardship, and procalcitonin (PCT) measurements help reduce duration of antibiotic therapy. We hypothesized that a strategy combining the use of mPCR with repeated PCT measurements would reduce antibiotic exposure during ACS.</div></div><div><h3>Methods</h3><div>We conducted a randomised, controlled, parallel group, open-label study in two French hospitals. Consecutive adult patients with ACS were randomly assigned to the conventional or interventional strategy, where antibiotic therapy was targeted on the results of mPCR performed on lower respiratory tract secretions (LRTS) samples, and antibiotic discontinuation based on PCT values and kinetics at Day 1 (D1), D3 and D7. The primary outcome was the number of days of antibiotic exposure at D28 after randomisation. This trial was registered on <span><span>ClinicalTrial.gov</span><svg><path></path></svg></span> (<span><span>NCT03919266</span><svg><path></path></svg></span>) and is closed to recruitment.</div></div><div><h3>Findings</h3><div>From June 2020 to September 2022, 72 patients were assigned to the interventional (n = 37) or conventional strategy (n = 35). Despite a higher rate of microbiological documentation with the intervention (n = 25; 67.6% versus n = 13; 37.1%; difference, 30.4%; 95% CI 6.7%–51.5%), antibiotic exposure at D28 was similar between the two strategies (6 days [4.0–8.0] versus 6 days [5.0–9.0], respectively; difference, 0.0 day; 95% CI, −2.1 to 2.1). The time to clinical stability, and ICU and hospital lengths of stay did not differ.</div></div><div><h3>Interpretation</h3><div>As compared with conventional tests, an enlarged respiratory panel mPCR combined with a PCT-guided algorithm did not reduce antibiotic exposure at D28 in adults with ACS.</div></div><div><h3>Funding</h3><div>Assistance Publique—Hôpitaux de Paris, AP-HP (CRC180159). A financial support for the multiplex PCR kits used in this study was partially provided by bioMérieux.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101234"},"PeriodicalIF":13.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143304208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of remnant cholesterol with unhealthy lifestyle and risk of coronary heart disease: a population-based cohort study
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-07 DOI: 10.1016/j.lanepe.2025.101223
Mia Ø. Johansen , Signe Vedel-Krogh , Sune F. Nielsen , Shoaib Afzal , George Davey Smith , Børge G. Nordestgaard
{"title":"Association of remnant cholesterol with unhealthy lifestyle and risk of coronary heart disease: a population-based cohort study","authors":"Mia Ø. Johansen ,&nbsp;Signe Vedel-Krogh ,&nbsp;Sune F. Nielsen ,&nbsp;Shoaib Afzal ,&nbsp;George Davey Smith ,&nbsp;Børge G. Nordestgaard","doi":"10.1016/j.lanepe.2025.101223","DOIUrl":"10.1016/j.lanepe.2025.101223","url":null,"abstract":"<div><h3>Background</h3><div>Unhealthy lifestyle is a major risk factor for coronary heart disease, which may be explained by elevated remnant cholesterol. However, this question remains incompletely clarified. In this study, we aimed to investigate whether elevated remnant cholesterol explains part of the excess risk of myocardial infarction and coronary heart disease in individuals with unhealthy lifestyle.</div></div><div><h3>Methods</h3><div>We included 104,867 individuals (58,286 women and 46,581 men) from the Copenhagen General Population Study free from coronary heart disease at examination. During a median follow-up of 9.2 years, 2484 developed myocardial infarction and 3570 developed coronary heart disease. To understand explained risk from elevated remnant cholesterol due to unhealthy lifestyle on risk of myocardial infarction and coronary heart disease, we used mediation analyses.</div></div><div><h3>Findings</h3><div>Current smoking, low physical activity, and low adherence to dietary guidelines were all associated with higher levels of remnant cholesterol. For current smoking, remnant cholesterol explained 15% (95% confidence interval: 9.7%–20%) of the excess risk of myocardial infarction and 16% (11%–21%) of the excess risk of coronary heart disease. Corresponding values for low physical activity were 20% (13%–27%) and 21% (15%–28%), and for low adherence to dietary guidelines 12% (6.6%–18%) and 14% (8.0%–19%), respectively. Results were similar in women and men separately and in analyses where each lifestyle factor were additionally adjusted for the other three lifestyle factors.</div></div><div><h3>Interpretation</h3><div>Elevated remnant cholesterol explained part of excess myocardial infarction and coronary heart disease in individuals with an unhealthy lifestyle. Clinically, these novel findings underline the importance of both elevated remnant cholesterol and promotion of healthy lifestyle in primary prevention of myocardial infarction and coronary heart disease.</div></div><div><h3>Funding</h3><div><span>Independent Research Fund Denmark</span>; <span>Johan Boserup and Lise Boserups Grant</span>; <span>Medical Research Council</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101223"},"PeriodicalIF":13.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adrenal aldosterone synthase (CYP11B2) histopathology and its association with disease-induced sudden death: a cross-sectional study
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-06 DOI: 10.1016/j.lanepe.2025.101226
Antero Ylänen , Juhani Isojärvi , Antti Virtanen , Helena Leijon , Tiina Vesterinen , Aapo L. Aro , Heini Huhtala , Eeva Kokko , Ilkka Pörsti , Marianna Viukari , Pasi I. Nevalainen , Niina Matikainen
{"title":"Adrenal aldosterone synthase (CYP11B2) histopathology and its association with disease-induced sudden death: a cross-sectional study","authors":"Antero Ylänen ,&nbsp;Juhani Isojärvi ,&nbsp;Antti Virtanen ,&nbsp;Helena Leijon ,&nbsp;Tiina Vesterinen ,&nbsp;Aapo L. Aro ,&nbsp;Heini Huhtala ,&nbsp;Eeva Kokko ,&nbsp;Ilkka Pörsti ,&nbsp;Marianna Viukari ,&nbsp;Pasi I. Nevalainen ,&nbsp;Niina Matikainen","doi":"10.1016/j.lanepe.2025.101226","DOIUrl":"10.1016/j.lanepe.2025.101226","url":null,"abstract":"<div><h3>Background</h3><div>Unidentified cardiovascular risk factors may account for approximately half of sudden deaths, a devastating event with limited preventive tools. We investigated whether adrenal histopathology suggestive of primary aldosteronism, pheochromocytoma, or adrenal masses could explain part of the risk for disease-induced sudden death (DSD).</div></div><div><h3>Methods</h3><div>In this study, autopsies and histopathological analyses, including aldosterone synthase staining of adrenal glands, were performed on 403 consecutive individuals who experienced sudden death. These individuals were classified into 258 cases of DSD and 144 deaths caused by trauma, suicide, or intoxication, i.e., non-disease-induced sudden death (nDSD). This trial was registered at <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> (<span><span>NCT05446779</span><svg><path></path></svg></span>).</div></div><div><h3>Findings</h3><div>Adrenal histopathology revealed changes in 31 (7.7%) subjects of the cohort. Of these, the most prevalent findings [25 (6.2%)] were aldosterone-producing adenomas (APA) or nodules (APN), which were associated with myocardial infarction and atherosclerosis at autopsy. Individuals in the DSD group and the subgroup with sudden cardiac death (SCD) were more likely to have APA or APN than individuals in the nDSD group [23 (8.9%) vs. 2 (1.4%), p = 0.002; 16 (8.8%) vs. 2 (1.4%), p = 0.003, respectively]. APA or APN were explanatory factors for DSD (odds ratio [OR] 6.47, 95% confidence interval [CI] 1.40–29.88, p = 0.017) and SCD (OR 10.68, 95% CI 2.02–56.43, p = 0.005). Other findings included two pheochromocytomas, one bilateral adrenal metastasis, and two unilateral adrenal metastases.</div></div><div><h3>Interpretation</h3><div>In this exploratory study, APA or APN were more frequently seen in DSD and SCD than nDSD cases. Whether primary aldosteronism constitutes a novel risk factor for sudden death warrants further study.</div></div><div><h3>Funding</h3><div>Finnish State Research funds and independent research foundations: <span>Aarne Koskelo Foundation</span>, the <span>Finnish Kidney Foundation</span>, and the <span>Finnish Foundation for Cardiovascular Research</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101226"},"PeriodicalIF":13.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143304207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimation of respiratory syncytial virus-associated hospital admissions in five European countries: a modelling study
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-05 DOI: 10.1016/j.lanepe.2025.101227
Caroline Klint Johannesen , David Gideonse , Richard Osei-Yeboah , Toni Lehtonen , Ombeline Jollivet , Rachel A. Cohen , Arantxa Urchueguía-Fornes , María Herrero-Silvestre , Mónica López-Lacort , Rolf Kramer , Thea K. Fischer , Terho Heikkinen , Harish Nair , Harry Campbell , Michiel van Boven
{"title":"Estimation of respiratory syncytial virus-associated hospital admissions in five European countries: a modelling study","authors":"Caroline Klint Johannesen ,&nbsp;David Gideonse ,&nbsp;Richard Osei-Yeboah ,&nbsp;Toni Lehtonen ,&nbsp;Ombeline Jollivet ,&nbsp;Rachel A. Cohen ,&nbsp;Arantxa Urchueguía-Fornes ,&nbsp;María Herrero-Silvestre ,&nbsp;Mónica López-Lacort ,&nbsp;Rolf Kramer ,&nbsp;Thea K. Fischer ,&nbsp;Terho Heikkinen ,&nbsp;Harish Nair ,&nbsp;Harry Campbell ,&nbsp;Michiel van Boven","doi":"10.1016/j.lanepe.2025.101227","DOIUrl":"10.1016/j.lanepe.2025.101227","url":null,"abstract":"<div><h3>Background</h3><div>Respiratory syncytial virus (RSV) can cause severe disease, notably among infants, older adults, and individuals with comorbidities. Non-systematic testing and differences in coding practices affect direct measures of the hospital disease burden. We aim to tackle this issue and estimate RSV-associated respiratory hospital admissions through time series modelling of hospital admissions.</div></div><div><h3>Methods</h3><div>The number of RSV hospital admissions in Denmark, England, Finland, the Netherlands, and Spain were estimated with attribution analyses, using age-specific respiratory tract infection (RTI) admissions combined with virological data, both from routinely collected healthcare data. Analyses covered the years 2016–2023.</div></div><div><h3>Findings</h3><div>The attributed incidence of RSV per 100,000 children 0–2 months ranged from 1715 in Denmark to 3842 in England. In older adults, substantial differences in the incidence of ICD-10 coded RSV hospitalisations were found, while the attributed RSV incidence was more comparable, ranging from approximately 100 per 100,000 in adults 65–74 years to 200 per 100,000 persons 75–84 years and 500 per 100,000 persons 85 years and older.</div></div><div><h3>Interpretation</h3><div>RSV-attributed time series exhibit a high degree of synchronicity between participating countries, suggesting that this method for attribution addresses the known issues with underdiagnosis and misclassification. In the older age groups, a substantial proportion of RTI hospitalisations is attributed to RSV, underscoring the relevance of RSV as a cause of severe respiratory infections.</div></div><div><h3>Funding</h3><div>This project has received funding from the <span>Innovative Medicines Initiative</span> 2 Joint Undertaking under grant agreement <span><span>101034339</span></span>. This Joint Undertaking receives support from the <span>European Union’s Horizon 2020</span> research and innovation programme and <span>EFPIA</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101227"},"PeriodicalIF":13.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143304135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
School phone policies and their association with mental wellbeing, phone use, and social media use (SMART Schools): a cross-sectional observational study
IF 13.6
Lancet Regional Health-Europe Pub Date : 2025-02-04 DOI: 10.1016/j.lanepe.2025.101211
Victoria A. Goodyear , Amie Randhawa , Péymane Adab , Hareth Al-Janabi , Sally Fenton , Kirsty Jones , Maria Michail , Breanna Morrison , Paul Patterson , Jonathan Quinlan , Alice Sitch , Rebecca Twardochleb , Matthew Wade , Miranda Pallan
{"title":"School phone policies and their association with mental wellbeing, phone use, and social media use (SMART Schools): a cross-sectional observational study","authors":"Victoria A. Goodyear ,&nbsp;Amie Randhawa ,&nbsp;Péymane Adab ,&nbsp;Hareth Al-Janabi ,&nbsp;Sally Fenton ,&nbsp;Kirsty Jones ,&nbsp;Maria Michail ,&nbsp;Breanna Morrison ,&nbsp;Paul Patterson ,&nbsp;Jonathan Quinlan ,&nbsp;Alice Sitch ,&nbsp;Rebecca Twardochleb ,&nbsp;Matthew Wade ,&nbsp;Miranda Pallan","doi":"10.1016/j.lanepe.2025.101211","DOIUrl":"10.1016/j.lanepe.2025.101211","url":null,"abstract":"<div><h3>Background</h3><div>Poor mental health in adolescents can negatively affect sleep, physical activity and academic performance, and is attributed by some to increasing mobile phone use. Many countries have introduced policies to restrict phone use in schools to improve health and educational outcomes. The SMART Schools study evaluated the impact of school phone policies by comparing outcomes in adolescents who attended schools that restrict and permit phone use.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional observational study with adolescents from 30 English secondary schools, comprising 20 with restrictive (recreational phone use is not permitted) and 10 with permissive (recreational phone use is permitted) policies. The primary outcome was mental wellbeing (assessed using Warwick–Edinburgh Mental Well-Being Scale [WEMWBS]). Secondary outcomes included smartphone and social media time. Mixed effects linear regression models were used to explore associations between school phone policy and participant outcomes, and between phone and social media use time and participant outcomes. Study registration: ISRCTN77948572.</div></div><div><h3>Findings</h3><div>We recruited 1227 participants (age 12–15) across 30 schools. Mean WEMWBS score was 47 (SD = 9) with no evidence of a difference between groups (adjusted mean difference −0.48, 95% CI −2.05 to 1.06, p = 0.62). Adolescents attending schools with restrictive, compared to permissive policies had lower phone (adjusted mean difference −0.67 h, 95% CI −0.92 to −0.43, p = 0.00024) and social media time (adjusted mean difference −0.54 h, 95% CI −0.74 to −0.36, p = 0.00018) during school time, but there was no evidence for differences when comparing usage time on weekdays or weekends.</div></div><div><h3>Interpretation</h3><div>There is no evidence that restrictive school policies are associated with overall phone and social media use or better mental wellbeing in adolescents. The findings do not provide evidence to support the use of school policies that prohibit phone use during the school day in their current form, and indicate that these policies require further development.</div></div><div><h3>Funding</h3><div><span>Public Health Research Programme</span>, <span>National Institute for Health and Care Research</span>, <span>Department of Health and Social Care</span>, UK.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"51 ","pages":"Article 101211"},"PeriodicalIF":13.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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