Lancet Regional Health-Europe最新文献

{"title":"Corrigendum to “Antihypertensive medication classes and risk of incident dementia in primary care patients: a longitudinal cohort study in the Netherlands” [The Lancet Regional Health—Europe, Volume 42, July 2024, 100927]","authors":"Jakob L. Schroevers , Marieke P. Hoevenaar-Blom , Wim B. Busschers , Monika Hollander , Willem A. Van Gool , Edo Richard , Jan Willem Van Dalen , Eric P. Moll van Charante","doi":"10.1016/j.lanepe.2024.101132","DOIUrl":"10.1016/j.lanepe.2024.101132","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101132"},"PeriodicalIF":13.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wealth and health: the neglected economic determinant","authors":"Rebeka Balogh, S Vittal Katikireddi","doi":"10.1016/j.lanepe.2024.101138","DOIUrl":"10.1016/j.lanepe.2024.101138","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"48 ","pages":"Article 101138"},"PeriodicalIF":13.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Country categorization of diversity in the pathway from medical student to specialist in the Netherlands","authors":"Lianne Mulder , Anouk Wouters , Eddymurphy U. Akwiwu , Andries S. Koster , Jan Hindrik Ravesloot , Saskia M. Peerdeman , Mahdi Salih , Gerda Croiset , Rashmi A. Kusurkar","doi":"10.1016/j.lanepe.2024.101139","DOIUrl":"10.1016/j.lanepe.2024.101139","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"48 ","pages":"Article 101139"},"PeriodicalIF":13.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"At the heart of the matter: do we still underestimate noise effects on cardiovascular health?","authors":"Barbara Hoffmann , Danielle Vienneau","doi":"10.1016/j.lanepe.2024.101134","DOIUrl":"10.1016/j.lanepe.2024.101134","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101134"},"PeriodicalIF":13.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Humoral and cellular responses to a fifth bivalent SARS-CoV-2 vaccine dose in patients with immune-mediated inflammatory diseases on tumour necrosis factor inhibitors: a prospective cohort study","authors":"Hilde S. Ørbo ,&nbsp;Taissa de Matos Kasahara ,&nbsp;Asia-Sophia Wolf ,&nbsp;Kristin H. Bjørlykke ,&nbsp;Joseph Sexton ,&nbsp;Ingrid Jyssum ,&nbsp;Anne T. Tveter ,&nbsp;Guri Solum ,&nbsp;Ingrid Fadum Kjønstad ,&nbsp;Sabin Bhandari ,&nbsp;Ingrid E. Christensen ,&nbsp;Tore K. Kvien ,&nbsp;Andreas Lind ,&nbsp;Hassen Kared ,&nbsp;Jørgen Jahnsen ,&nbsp;Espen A. Haavardsholm ,&nbsp;Ludvig A. Munthe ,&nbsp;Sella A. Provan ,&nbsp;John T. Vaage ,&nbsp;Siri Mjaaland ,&nbsp;Guro Løvik Goll","doi":"10.1016/j.lanepe.2024.101121","DOIUrl":"10.1016/j.lanepe.2024.101121","url":null,"abstract":"<div><h3>Background</h3><div>As most people now have established hybrid immunity, the need for regular, updated SARS-CoV-2 vaccine boosters in patients with immune-mediated inflammatory diseases (IMIDs) is unclear. The study aim was to assess humoral and cellular immunogenicity of a fifth bivalent vaccine dose in patients with IMID on tumour necrosis factor inhibitors (TNFi).</div></div><div><h3>Methods</h3><div>In the longitudinal, observational Nor-vaC study, we assessed anti-spike and neutralising antibodies against Wuhan, Omicron BA.1 and BA.4, as well as frequency and polyfunctionality of responding T cells, following a fourth monovalent and a fifth bivalent (BA.1 or BA.4/5) vaccine dose in patients with or without hybrid immunity using TNFi.</div></div><div><h3>Findings</h3><div>Between December 17, 2021, and June 20, 2023, 456 infection-naïve patients with IMIDs using TNFi received a fourth vaccine dose and were otherwise eligible for inclusion. A total of 373/456 (82%) received a fifth vaccine dose, of these 190/373 (51%) had hybrid immunity defined as having had COVID-19 between the fourth and fifth dose. In patients with hybrid immunity, the fifth dose did not induce improved humoral responses compared to infection, neither with BA.1 (median anti-spike antibody concentrations 23,244 IU/ml (IQR 15,138–45,233) vs 36,341 IU/ml (11,887–53,710), p = 0.52) nor BA.4/5 (31,693 IU/ml (15,176–54,186), p = 0.30). Comparison of neutralising antibodies yielded similar results. In infection-naïve patients, a fifth BA.4/5 vaccine, but not the BA.1, induced slightly higher humoral responses (18,890 IU/ml (6494–50,211)) compared to the fourth dose (7304 IU/ml (3245–17,260), p &lt; 0.0001). CD8 T cell responses remained stable following a fourth dose (median frequency of spike-specific cells 0.039% (IQR 0.010–0.14)), infection (0.058% (0.026–0.17)) and a fifth dose (0.058% (0.013–0.20).</div></div><div><h3>Interpretation</h3><div>In patients on TNFi with hybrid immunity, there was no immunological benefit of an updated fifth SARS-CoV-2 booster dose. Stable CD8 cellular responses following four doses indicate established protective immunity. Patients whose only risk factor is TNFi may in future follow vaccine recommendations for the general population.</div></div><div><h3>Funding</h3><div>The <span>South-Eastern Norway Regional Health Authority</span>, The <span>Coalition for Epidemic Preparedness Innovations</span> (CEPI), <span>Diakonhjemmet Hospital</span>, <span>Akershus University Hospital</span>, <span>Oslo University Hospital</span>, <span>University of Oslo</span>, The <span>Norwegian Research Council</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"48 ","pages":"Article 101121"},"PeriodicalIF":13.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Residential exposure to transportation noise and risk of incident atrial fibrillation: a pooled study of 11 prospective Nordic cohorts” [The Lancet Regional Health – Europe, Volume 46, November 2024, 101091]","authors":"Jesse D. Thacher ,&nbsp;Nina Roswall ,&nbsp;Mikael Ögren ,&nbsp;Andrei Pyko ,&nbsp;Agneta Åkesson ,&nbsp;Anna Oudin ,&nbsp;Annika Rosengren ,&nbsp;Aslak H. Poulsen ,&nbsp;Charlotta Eriksson ,&nbsp;David Segersson ,&nbsp;Debora Rizzuto ,&nbsp;Emilie Helte ,&nbsp;Eva M. Andersson ,&nbsp;Gunn Marit Aasvang ,&nbsp;Gunnar Engström ,&nbsp;Hrafnhildur Gudjonsdottir ,&nbsp;Jenny Selander ,&nbsp;Jesper H. Christensen ,&nbsp;Jørgen Brandt ,&nbsp;Karin Leander ,&nbsp;Mette Sørensen","doi":"10.1016/j.lanepe.2024.101129","DOIUrl":"10.1016/j.lanepe.2024.101129","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101129"},"PeriodicalIF":13.6,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compromises in determination of Mycoplasma pneumoniae incidence","authors":"Helene Kildegaard,&nbsp;Annmarie T. Lassen","doi":"10.1016/j.lanepe.2024.101131","DOIUrl":"10.1016/j.lanepe.2024.101131","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101131"},"PeriodicalIF":13.6,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Effectiveness of an unguided modular online intervention for highly anxious parents in preventing anxiety in their children: a parallel group randomised controlled trial” [The Lancet Regional Health – Europe, Volume 45, October 2024, 101038]","authors":"Abby Dunn ,&nbsp;James Alvarez ,&nbsp;Amy Arbon ,&nbsp;Stephen Bremner ,&nbsp;Chloe Elsby-Pearson ,&nbsp;Richard Emsley ,&nbsp;Christopher Jones ,&nbsp;Peter Lawrence ,&nbsp;Kathryn J. Lester ,&nbsp;Natalie Morson ,&nbsp;Julia Simner ,&nbsp;Abigail Thomson ,&nbsp;Sam Cartwright-Hatton","doi":"10.1016/j.lanepe.2024.101128","DOIUrl":"10.1016/j.lanepe.2024.101128","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101128"},"PeriodicalIF":13.6,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between gambling disorder and suicide mortality: a comparative cohort study using Norwegian health registry data","authors":"Joakim Hellumbråten Kristensen ,&nbsp;Carl Michael Baravelli ,&nbsp;Tony Leino ,&nbsp;Ståle Pallesen ,&nbsp;Mark D. Griffiths ,&nbsp;Eilin Kristine Erevik","doi":"10.1016/j.lanepe.2024.101127","DOIUrl":"10.1016/j.lanepe.2024.101127","url":null,"abstract":"<div><h3>Background</h3><div>Gambling disorder has been consistently linked to suicidal ideation and suicide attempts, but few studies have investigated the association between gambling disorder and suicide mortality. This study examined the risk of suicide mortality associated with gambling disorder compared to the general population and other patient groups.</div></div><div><h3>Methods</h3><div>A registry-based cohort study was conducted employing individual-level linked and aggregated data from Norwegian nationwide health registries. The study population comprised all patients with gambling disorder in Norway (<em>n</em> = 6899) for the period 2008 to 2021. Standardized mortality ratios were estimated to assess suicide risk among gambling disorder patients against the adult Norwegian general population. Cox regressions were used to estimate hazard ratios comparing suicide risk among patients with gambling disorder to 12 comparison groups comprising patients treated for other conditions (<em>n</em> = 391,897).</div></div><div><h3>Findings</h3><div>Suicide was the leading cause of death among patients with gambling disorder (37 of 148 deaths; 25%). Patients with gambling disorder had a higher suicide risk than the general population (standardized mortality ratio = 5.12, 95% CI [3.71; 7.06]), and 5 of 12 patient groups with other conditions. Suicide risk was not significantly different when compared to that of patients with anxiety disorders, personality disorders, or depression. However, suicide risk was lower among patients with gambling disorder than patients with substance use disorders, alcohol dependence, psychotic disorders, or mood disorders.</div></div><div><h3>Interpretation</h3><div>Norwegian patients with gambling disorder have an elevated risk of suicide mortality but the risk is similar to or lower than other patient groups known to be at increased suicide risk.</div></div><div><h3>Funding</h3><div><em>Norwegian Competence Center for Gambling and Gaming Research</em> and the Faculty of Psychology at the <span>University of Bergen</span> (no specific grant).</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"48 ","pages":"Article 101127"},"PeriodicalIF":13.6,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital narratology for people with psychosis experience","authors":"Stefan Gutwinski ,&nbsp;Alva Lütt","doi":"10.1016/j.lanepe.2024.101126","DOIUrl":"10.1016/j.lanepe.2024.101126","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101126"},"PeriodicalIF":13.6,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}