Oftal''mokhirurgiia最新文献

{"title":"Clinical Hospital of the Office of the President of the Russian Federation, Moscow, Russian Federation","authors":"I.E. Ioshin, A.V. Rakova, I.V. Maksimov, E.A. Berezenko","doi":"10.25276/0235-4160-2023-3-57-64","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-57-64","url":null,"abstract":"Purpose. To evaluate the safety and efficacy of different laser energy parameters when performing micropulse transscleral cyclophotocoagulation (MP-TSCPC) in patients with different stages of primary open-angle glaucoma (POAG). Material and methods. 177 patients with moderate (47) and advanced (130) stages of primary open-angle glaucoma were under observation. All patients underwent repeated laser (mean 1,3±0,6) and surgical (mean 1,78±0,7) penetrating and nonpenetrating antiglaucoma surgeries. According to the amount of total energy during MP-TSCPC, patients were divided into 2 groups. The protocol of the first group (117 patients) included a total energy of 125J, fluence of 121,8 J/cm² . The protocol of the second group included increased energy (60 patients) where the total energy was 150 J, fluence 152 J/cm² . Results. Surgery and postoperative period in all patients were areactive. According to the data obtained when comparing the two groups on Kaplan – Meier chart, after 12 months of observation the group of patients with the fluence of 152J/cm² showed better results. A positive result was achieved in 95% of cases, compared to 87,1% in patients in the first group with an fluence of 121,8 J/cm². Conclusion. MP-TSCPC in patients with POAG with a fluence of 121,8 J/сm² and a total energy of 125 J and a fluence of 152 J/сm² and a total energy of 150 J is an effective and safe treatment method. The success parameters evaluated according to the Kaplan – Meier criterion showed that performing MP-TSCPC with 150 J energy was more effective than with 125 J. In the first group, 87,1% (102 out of 117 patients) success was achieved in up to 12 months of follow-up. In 60 patients with a higher energy (150 J), MP-TSCPC resulted in a long-term hypotensive effect in 95% (57 out of 60 patients) in the same period of observation. Key words: open angle glaucoma, intraocular pressure, micropulse cyclophotocoagulation, fluence","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"281 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and functional results of idiopathic macular holes treatment with foveal internal limiting membrane sparing","authors":"A.A. Shpak, F.A. Avakyan, A.I. Kolesnik","doi":"10.25276/0235-4160-2023-3-78-85","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-78-85","url":null,"abstract":"Purpose. To evaluate clinical and functional results of originally developed technique of preserving foveal internal limiting membrane (ILM) in the surgical treatment of idiopathic macular holes (IMH) with a minimum diameter of less than 500μm in comparison with standard technique that does not require preservation of the foveal ILM. Material and methods. This study included 75 patients (75 eyes) with IMH with a minimum diameter of less than 500μm and complaints manifestation of no more than 12 months. 35 patients (35 eyes, control group) were operated using standard technique. In 40 patients (40 eyes, main group) surgical intervention was performed using originally developed technique of foveal ILM sparing. Results. The anatomical closure of the IMH after surgery was obtained in all 75 patients. In two patients (one in the main and one in the control groups) within 1 month after surgery, a recurrence of IMH developed. All functional results in the main group had significant positive dynamics if compared with control group: increase in central and general light sensitivity, spatial contrast sensitivity, low-contrast visual acuity without and with glare. The increase in the best corrected visual acuity was also greater in the main group, but the difference from the control group was not significant. Conclusion. Originally developed technique of preserving the foveal ILM is highly effective in the surgical treatment of IMH with a minimum diameter of less than 500μm. In comparison with the standard technique of surgery with the removal of the ILM, this technique allows to achieve higher functional results with an equal frequency of positive anatomical outcomes. Key words: idiopathic macular hole, ILM peeling, surgical treatment, foveal sparing, ILM peeling, light sensitivity, contrast sensitivity, low contrast visual acuity","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental treatment of endophthalmitis caused by multidrug-resistant Pseudomonas aeruginosa infection with nanoparticle-based conjugates.","authors":"V.O. Ponomarev, V.N. Kazaikin, K.A. Tkachenko, V.L. Timofeev, A.G. Dudorov","doi":"10.25276/10.25276/0235-4160-2023-3-86-96","DOIUrl":"https://doi.org/10.25276/10.25276/0235-4160-2023-3-86-96","url":null,"abstract":"Relevance. Pseudomonas aeruginosa (PA) is an extremely dangerous microorganism whose elimination from the host organism is very difficult due to the presence of multidrug resistance (MDR) factors in PA. The outcome of endophthalmitis (EP) mediated by PA in 50% of cases will be evisceration of the eyeball, and more than 95% of patients receive visual acuity – hand movements near the face and below. In this regard, studies of quantum dots (QDs), which have shown high anti-infective activity in laboratory conditions, are of particular relevance. Purpose. Evaluation of the effectiveness of the treatment of EP caused by PA with MDR using QDs-based conjugates in the experiment. Material and methods. The object of the study was laboratory rabbits of the Chinchilla breed (n=27), male, aged from 3 to 3.5 months. As an EP inducer, all laboratory animals underwent intravitreal injection (IVI) of a multidrug-resistant PA strain in a volume of 0.05 ml in the right eye. QDs of the Ag (10%):InP/ZnS MPA type were taken as the basis for the creation of conjugates with antibiotics (AB). After the manifestation of EP, the animals underwent intravitreal injections (IVI) of dosage forms in accordance with the distribution into the following subgroups, 3 rabbits in each. Subgroups No. 1–3 – IVI 2.25 mg/0.1 ml Ceftazidime. Subgroups No. 4–6 – IVI 0.1 ml of QDs solution at concentrations of 10%, 0.1%, 0.01%, respectively. Subgroups No. 7–9 – IVI solution of QDs 0.05 ml (at concentrations of 10%, 0.1%, 0.01%, respectively) in combination with 2.25 mg/0.05 ml of Ceftazidime (conjugates). Efficacy was evaluated based on clinical parameters: the dynamics of hypopyon resorption, the presence of inflammatory cells in the anterior chamber, the dynamics of regression of pathological suspension in the vitreal cavity, the dynamics of pathological neovascularization of the iris, the dynamics of the cornea. Results. Rabbits from subgroups No. 1–3 (1st group) were characterized by the least dynamics in relation to the regression of symptoms during the 7-day observation period. Rabbits from subgroups No. 4–6 (2nd group) were characterized by moderate positive dynamics in relation to the regression of symptoms. Rabbits from subgroups No. 7–9 (3rd group) were characterized by the best positive dynamics in relation to the regression of symptoms. Conclusion. It was possible to prove the effectiveness of the treatment of experimental antibiotic-resistant EP caused by a strain of PA with MDR by means of QDs Ag(10%):InP/ZnS MPA at concentrations of 10%, 0.1% and 0.01%, especially in combination with 2.25 mg/0.05 ml of Ceftazidime in as a conjugate. Based on the results obtained, it can be assumed that active research and the use of QDs as conjugates with modern ABs can solve the overall problem of combating MDR strains. Key words: Pseudomonas Aeruginosa, quantum dots, endophthalmitis, multidrug resistance, antibiotic resistance, conjugates","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135666006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of cataracts surgical treatment in patients after ARK using IOL power calculation basic formulas","authors":"E.K. Tsirenzhapova, O.I. Rozanova","doi":"10.25276/0235-4160-2023-3-6-13","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-6-13","url":null,"abstract":"Purpose. To analyze possible refractive errors when calculating IOL power in patients after ARK (anterior radial keratotomy). Material and methods. The data of Intraocular lens (IOL) power calculation in 46 patients (46 eyes) with anterior radial keratotomy (ARK) who also underwent cataract surgery were analyzed. The IOL calculation was performed taking into account the data obtained by the Lenstar LS 900 (HAAG-STREIT AG, Switzerland) and keratotopography (Pentacam HR, Oculus, Germany), with a target refraction corresponding to emmetropia up to ±0.50 D. Results. The analysis of the clinical efficacy of phacoemulsification with IOL implantation in patients after ARK with the refractive error (RE) calculation and refractive prediction error (RPE) calculation according to the basic formulas were performed. It was found that emmetropia (up to ±0.5 D) in the postoperative period was achieved in 52% of cases. The value of the postoperative RPE had no reliable dependence on the values of the eyeball length, it was depended on the corneal optical power in the central zone of the cornea only with some formulas for IOL calculation (Barrett, Barrett Universal II, MIKOFRK/ALF). The obtained results of the analysis provide justification for a deeper study of post keratotomy corneal deformation as a pathological condition with the presence of hidden risk factors. Conclusion. Phacoemulsification with IOL implantation in patients with previously performed ARK is accompanied by the achievement of target refraction in 52% of cases. The high proportion of IOL calculation errors in cataract surgery in patients after ARK largely depends on hidden factors, which determines the need for a detailed study of post keratotomy corneal deformation as a pathological condition. Key words: IOL power calculation, anterior radial keratotomy, emmetropia","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the corneal epithelium after myopia correction by SMILE and FemtoLASIC methods","authors":"O.V. Pisarevskaya, T.N. Iurieva, A.G. Shchuko, T.N. Frolova, N.R. Nadelyaeva","doi":"10.25276/0235-4160-2023-3-50-56","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-50-56","url":null,"abstract":"Purpose. To conduct a comparative analysis of the thickness and topographic distribution of the corneal epithelium at various stages of the postoperative period in patients with moderate myopia after refractive surgery performed by SMILE and FemtoLASIK methods. Material and methods. A total amount of 152 patients with moderate myopia were examined. Depending on the type of refractive surgery, two comparison groups were formed: group 1 – 68 patients with moderate myopia operated by the SMILE method; group 2 – 84 patients with moderate myopia operated by FemtoLASIK. Examinations were performed before surgery and in the postoperative period 1, 5 days, 3, 6, 12 months after surgery. Results. The total epithelial thickness index after SMILE surgery changed in general by the year from 52.41±8.45 to 55.21±9.01 (p>0.05). After FemtoLASIK surgery, there was a gradual increase in epithelial thickness from the first day to a year, without a clear tendency to stabilization, from 51.77±10.09 to 57.30±9.5 (p<0.001). The difference between the comparison groups was statistically significant (p<0.05). The topographic difference of the maximum indices of epithelial hypertrophy in different types of surgery was also noted. Conclusion.SMILE technology is accompanied by asymmetric hypertrophy of the epithelium in the temporal and lower temporal zones which is completed by the 3rd month of the postoperative period. Unlike FemtoLASIK is characterized by almost one and a half times excess of the thickness of the corneal epithelium and the absence of significant stabilization even 12 months after surgery, which indicates ongoing corneal remodeling and incomplete process of postoperative healing. Key words: myopia, SMILE, FemtoLASIK, epithelial hypertrophy, femtosecond laser","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135666004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental application of 1% hydroxypropylmethylcellulose for corneal endothelium protection during inverted posterior lamellar corneal graft preparation technique by low-energy femtosecond laser","authors":"B.E. Malyugin, S.A. Borzenok, I.S. Tkachenko, D.S. Ostrovskiy, S.Y. Kalinnikova","doi":"10.25276/0235-4160-2023-3-26-36","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-26-36","url":null,"abstract":"Purpose. To evaluate experimentally endothelial cell loss of animal's cornea during inverted posterior lamellar corneal graft preparation technique by low-energy femtosecond laser with and without ophthalmic viscosurgical device (OVD) – 1% hydroxypropyl methylcellulose (HPMC) solution application. Material and methods. Posterior lamellar corneal grafts were created using a femtosecond laser (FSL). In the control group (n=16), a few drops of corneal storage solution were applied to the endothelium just before applanation, in the experimental group (n=16) – 1% HPMС. The quality of the applanation were monitored using an integrated in laser OCT system. The endothelial viability was determined using live/dead cells assay and the grafts were examined on a confocal laser scanning microscope. The obtained images were analyzed to count live and dead endothelial cells (EC). To assess the state of collagen fibers of the stromal side of the graft, samples from the control and experimental groups were examined using a scanning electron microscope (SEM). Results. According to the OCT, in all samples of both groups, a flat profile of the contact zone between the laser head and the endothelial monolayer was observed during applanation. The difference between the number of live and dead ECs was statistically significant between both groups. There were 2854 [2819; 2879] live cells/mm² in the control group, and 3477 [3426; 3719] live cells/mm² in the experimental group (p<0.001). Thus, the number of dead ECs in the control group was 710 [649; 728] cells/mm² . The number of dead ECs in the experimental group was 402 [366; 427] cells/mm² (p<0.001). When analyzing the images obtained on a SEM, the preservation of the architectonics of the graft collagen fibers with their single defibrations in both groups was observed. Conclusion. Application of 1% HPMC provides protection for endothelial cells from damage during posterior laser dissection using an FSL. In the study group, the number of endothelial cells was 9.92% higher than in the control group. The presence of the OVD layer in the interface between the head of the FSL and the EC did not affect the formation of an effective laser cut and did not reduce the quality of the stromal surface of the graft. The inverted technique FSL cut using a 1% solution of HPMC on the surface of the endothelium may be recommended for use in clinical practice. Key words: endothelium, keratocytes, corneal transplantation, keratoplasty, posterior lamellar keratoplasty, femtosecond laser, ophthalmic viscosurgical device, hydroxypropyl methylcellulose, confocal microscopy, scanning electron microscopy","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of changes in the retinal ellipsoid zone before and after surgical treatment of penetrating macular holes","authors":"D.I. Bronskii, V.A. Zaika, A.P. Yakimov","doi":"10.25276/0235-4160-2023-3-72-77","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-72-77","url":null,"abstract":"Relevance. Restoring the retinal integrity during surgical treatment of macular holes (MH) does not always guarantee a significant improvement in visual acuity in the postoperative period. The possibility of regeneration of the retinal ellipsoid zone (EZ), as well as the relationship between the structural restoration of the outer retina and the improvement of visual functions are very contradictory. Purpose. To assess the possibility and degree of repair of the ellipsoid zone in the early and long-term postoperative treatment of MH of medium and large diameters. Material and methods. A prospective study of 13 patients (13 eyes) – 12 women and 1 man with a MH of medium and large diameters was conducted. Patients were divided into 2 groups depending on the presence or absence of an EZ defect after 6 months postoperatively. The structure of the retina was evaluated according to OCT data and the visual acuity of patients in the distance before surgery, 1, 3 and 6 months after MR surgery. Results. In patients with complete restoration of retinal EZ, the initial size of the holes was 1.5 times smaller than in the comparison group, the time from the moment of diagnosis to surgery was 122.7±51.8 and 383.5±125.7 days, respectively. The defect of photoreceptors of the EZ by 1 month after surgery in patients of the first and second groups was 369.6±245.61 microns and 276.07±233.37 microns, respectively. By 6 months of follow–up in the first group, complete closure of the defect was observed, in the second group its decrease to 91.61±97.51 microns, while visual acuity in the first group was 0.46±0.83 by six months of followup and in 3 out of 5 cases it increased to 0.6–0.9, in the second group in all cases this indicator did not exceed 0.5. Conclusion. Complete regeneration of EZ was observed in 38.5% of cases 6 months after surgery, however, anatomical repair of the photoreceptor field of the macular area in the postoperative period does not guarantee improvement of visual functions in all patients. Key words: macular hole, ellipsoid zone, ellipsoid zone regeneration","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of graft survival after FS-DSEK in patients with glaucoma operated by various methods","authors":"K.I. Katmakov, N.A. Pozdeyeva, A.N. Pashtaev, N.P. Pashtaev, E.M. Mamedova, A.M. Gelyastanov","doi":"10.25276/0235-4160-2023-3-38-49","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-38-49","url":null,"abstract":"Purpose. To evaluate the graft survival in the dynamics of the postoperative period of FS-DSEK in patients with concomitant glaucoma. Material and methods. In total 52 eyes were operated, 32 of them with glaucoma compensated by medication (1st group), 8 with glaucoma operated by implantation of the Ahmed valve model FP8 (2nd group) and 12 with glaucoma operated by microinvasive non-penetrating deep sclerectomy with implantation of collagen antiglaucoma drainage (3rd group). All patients have a follow-up of 12 months. Results. By 1 year, the «cornea + graft» complex retained its transparency in group 1 in 84.4% of eyes (27 out of 32 eyes), in group 2 in 87.5% of cases (7 out of 8 eyes), in group 3 in 75% of cases (9 out of 12 eyes). The highest percentage of endothelial cell loss at 12 months was observed in 2nd group (Ahmed valve) – 45,4±19,5%. In other groups, endothelial cell loss was 41,8±9,1% (group 3) and 39,6±15,2% (1st group). Conclusion. Clinical results show a lower percentage of graft survival after FS-DSEK in the operated glaucoma groups. Accumulation of clinical material and further study of patterns are required. Key words:posterior lamellar keratoplasty, glaucoma, femtosecond laser, endothelial corneal dystrophy","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135666002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classifications of peripheral retinal dystrophies","authors":"O.M. Stanishevskaya, M.A. Glock, M.A. Safronova, A.I. Belyaeva, D.V. Chernykh","doi":"10.25276/0235-4160-2023-3-119-124","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-119-124","url":null,"abstract":"Purpose. To analyze the existing classifications of peripheral retinal dystrophies. Material and methods. While writing a literature review, a search was made for data from domestic and foreign literature, mostly in the last 20 years. The search was carried out using the following keywords: «peripheral retinal dystrophies», «retinal detachment», «laser coagulation», «lattice degeneration». In total, 20 articles were selected that relate to the topic of this literature review. Results. Retinal detachment is a severe pathology leading to a significant reduction or loss of vision. Peripheral retinal dystrophies play a leading role in the development of retinal detachment. The leading role in the development of rhegmatogenous forms of peripheral degenerations is assigned to changes in the vitreous body with a traction effect on the retina. The question of the incidence of retinal detachment in its dystrophies remains debatable. In publications, we came across a large number of classifications of peripheral retinal dystrophies, covering from 8 to 20 different clinical forms. The question of which retinal dystrophies are predisposing or not predisposing to retinal detachment remains open. Visualization of the vitreoretinal interface in peripheral degenerations is relevant for determining treatment tactics. Optical coherence tomography is highly informative in the early diagnosis of the traction component, visualization of retinal tears and detachment, and determination of indications for laser coagulation of the retina. Conclusion. Retinal detachment is a severe pathology leading to a significant reduction or loss of vision. Peripheral retinal dystrophies play a leading role in the development of retinal detachment. The question of the incidence of retinal detachment in its dystrophies remains debatable. The issue of creating a working classification that reflects the morphology of the degenerative process and indications for laser treatment remains relevant. Key words: peripheral retinal dystrophy, retinal detachment, retinal laser treatment, lattice degeneration","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"181 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135666003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphofunctional retinal pigment epithelium changes in normal eye and age-related macular degeneration","authors":"R.R. Fayzrakhmanov, E.D. Вosov, V.A. Bogdanova, E.E. Vaganova, O.L. Sekhina","doi":"10.25276/0235-4160-2023-3-106-111","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-3-106-111","url":null,"abstract":"Relevance. The retinal pigment epithelium performs a number of highly specialized functions. The relevance of studying morphological changes in the pigment epithelium is associated with an increased number of patients with age-related macular degeneration (AMD), polypoid choroidal vasculopathy, central serous retinopathy and retinitis pigmentosa. The increase in the number of patients with these pathologies is associated both with the general trend of aging of the world's population and with modern opportunities for mass diagnostics. Pathomorphological changes in the pigment layer are an important indicator of the development of AMD. Purpose. To analyze features of retinal pigment epithelium in normal and pathological conditions. Material and methods. The literature review was carried out using PubMed and Sochape Library. Results. Several authors present data about the complication of retinal detachment with development of the retinal pigment epithelium tear. The key criterion for tear treatment is the height of the pigment layer detachment. Violation of the integrity of the pigment layer in the long term is a factor in decrease or complete loss of vision. This is especially characteristic when a tear is formed in the central area of the retina. Also, visual impairment is observed in cases of submacular hemorrhage and fibrous scar formation. Conclusion. An important point, at present, is guidelines development for patients with pigment epithelium tears, it will allow to manage this condition on the background of concomitant disease. Key words: retinal pigment epithelium, age-related macular degeneration, pigment epithelium tear","PeriodicalId":52983,"journal":{"name":"Oftal''mokhirurgiia","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}