South African Journal of Oncology最新文献_第4页

Management of a malignant tumor of the endometrium in a subject over 80 years old: About a case at the Regional Hospital of Fatick 80岁以上患者子宫内膜恶性肿瘤的处理:关于Fatick地区医院的一个病例

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.83

A. Touré, A. Mihimit, O. Oumar, H. Baldé, B. Camara, B. Traoré, S. Ka, A. Dem

{"title":"Management of a malignant tumor of the endometrium in a subject over 80 years old: About a case at the Regional Hospital of Fatick","authors":"A. Touré, A. Mihimit, O. Oumar, H. Baldé, B. Camara, B. Traoré, S. Ka, A. Dem","doi":"10.54266/ajo.2.2.83","DOIUrl":"https://doi.org/10.54266/ajo.2.2.83","url":null,"abstract":"INTRODUCTION: The gynecological tumors of the patient aged over 70 constitute heterogeneous entities by their oncological and geriatric clinical presentations, which frequently expose to the proposal of “non-standard”, “adapted” or “exceptional” therapies. In Sub-Saharan Africa, cancer is a scourge whose characteristics remain to be clarified, marked by very limited means, and especially by the context of practice in rural areas. We describe in this clinical case the particularity of the management in a rural context of a case of endometrial tumor in an 83-year-old patient at stage IB. OBSERVATION: This is Mrs. M.G., aged 83 4G 4P 4 children, postmenopausal for 30 years who consults for postmenopausal metrorrhagia evolving for 3 months. A diagnostic hysteroscopy was performed showing an ulcerated mass of the uterine cavity bleeding on contact, a biopsy was performed, the result of which was a low-grade endometrial stromal sarcoma. The abdominopelvic CT scan, which demonstrates thickening of the endometrium without damage to surrounding structures, classified as stage IB endometrial tumor. The patient underwent a total hysterectomy with bilateral pelvic dissection. The postoperative course was simple. The patient was discharged on the 7th postoperative day. The result of the histological report: well-differentiated and infiltrating endometroid carcinoma invading the isthmus and the cervix. Parameters and the 4 right and left lymph nodes are unharmed. The histo-prognostic stage was pT2N0Mx. CONCLUSION: The management of endometrial cancer is possible in the rural context in elderly patients. The prognosis is good if the diagnosis is made at an early stage. Surgery could still be offered even for subjects over 80 with less comorbidity. KEYWORDS: Endometrial tumors; Elderly patient; Senegal.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"80 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90938066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory breast cancer: Epidemiological, diagnostic, therapeutic and evolutionary aspects. About 43 cases at the Joliot-Curie Institute in Dakar 炎性乳腺癌:流行病学、诊断、治疗和进化方面。达喀尔约里奥-居里研究所约有43例病例

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.58

M. Guira, O. M. S. Apithy, Mohammed Ezzet Charfi, H. Sawadogo, N. Zongo, Sidy Ka, A. Dem

{"title":"Inflammatory breast cancer: Epidemiological, diagnostic, therapeutic and evolutionary aspects. About 43 cases at the Joliot-Curie Institute in Dakar","authors":"M. Guira, O. M. S. Apithy, Mohammed Ezzet Charfi, H. Sawadogo, N. Zongo, Sidy Ka, A. Dem","doi":"10.54266/ajo.2.2.58","DOIUrl":"https://doi.org/10.54266/ajo.2.2.58","url":null,"abstract":"OBJECTIVE: To clarify the epidemiological, diagnostic and therapeutic features and to improve the prognosis of inflammatory breast cancer. MATERIALS AND METHODS: This is a retrospective study from January 1, 2018 to December 31, 2020 including patients with a diagnosis of inflammatory breast cancer. RESULTS: During the study, 1.730 cases of breast cancer were collected, of which 43 cases of inflammatory cancer (2.5%). The average age of the patients was 44.8 years. The average consultation time was 6.4 months. All patients had lymph node involvement. Non-specific infiltrating carcinoma was the histological type found in all cases. All patients received at least a first line of chemotherapy with a better clinical response to taxanes than to anthracyclines. Surgery was performed in 69.76% of cases. Forty percent of patients were alive at the end of the study. CONCLUSION: Inflammatory breast cancer is quite rare at the Joliot-Curie Institute. The diagnosis is late. Early diagnostic and therapeutic management would improve the therapeutic outcome of inflammatory breast cancer. KEYWORDS: Inflammatory breast cancer; Epidemiology; Prognosis.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82423045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supracricoid partial laryngectomy with reconstruction: Technique, indications and outcomes at Hôpital Principal de Dakar 肩胛上部分喉切除术重建:技术，适应症和结果Hôpital达喀尔校长

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.69

C. Lame, B. Loum, T. B. Diallo, C. Ndiaye, A. Ndiaye, A. Diouf, M. Ndiaye, B. Diallo

{"title":"Supracricoid partial laryngectomy with reconstruction: Technique, indications and outcomes at Hôpital Principal de Dakar","authors":"C. Lame, B. Loum, T. B. Diallo, C. Ndiaye, A. Ndiaye, A. Diouf, M. Ndiaye, B. Diallo","doi":"10.54266/ajo.2.2.69","DOIUrl":"https://doi.org/10.54266/ajo.2.2.69","url":null,"abstract":"OBJECTIVE: To report technique, indications and outcomes of supracricoid partial laryngectomy (SPL) with crico-hyoido-epiglottopexy (CHEP) or crico-hyoidopexy (CHP) for laryngeal cancers at Hôpital Principal de Dakar. MATERIALS AND METHODS: Retrospective study carried out from January 2009 to December 2016 in the ENT department of Hôpital Principal de Dakar including all patients who underwent SPL with reconstruction for laryngeal cancer. RESULTS: Six patients underwent SPL with CHEP or CHP for laryngeal squamous cell carcinoma. The lesions were classified as T1, T2 or T3. Functional outcomes were simple with normal swallowing and satisfactory voice quality. One patient presented with a local recurrence that motivated total salvage laryngectomy. CONCLUSION: SPL with reconstruction is a good alternative in the management of limited laryngeal cancers. It gives good oncological outcomes while preserving laryngeal functions. However, candidates must be selected and the technique rigorous. KEYWORDS: Cancer; Larynx; Partial laryngectomy; crico-hyoïdo-epiglottopexy; crico-hyoïdopexy.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81140828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kidney cancer in adults at the University Hospital of Tengandogo: epidemiological, clinical, histopathology and therapeutic aspects 腾甘多戈大学医院的成人肾癌:流行病学、临床、组织病理学和治疗方面

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.50

B. Ouedraogo, H. Karama, T. Hafing, O. Traoré, A. Korgo, S. Pamba, A. Ndormadjita, F. A. Kaboré, B. Ouedraogo, A. Sanou

{"title":"Kidney cancer in adults at the University Hospital of Tengandogo: epidemiological, clinical, histopathology and therapeutic aspects","authors":"B. Ouedraogo, H. Karama, T. Hafing, O. Traoré, A. Korgo, S. Pamba, A. Ndormadjita, F. A. Kaboré, B. Ouedraogo, A. Sanou","doi":"10.54266/ajo.2.2.50","DOIUrl":"https://doi.org/10.54266/ajo.2.2.50","url":null,"abstract":"OBJECTIVE: To study the epidemiological, clinical and histopathological aspects of renal cancers at the University Hospital of Tengandogo. MATERIALS AND METHODS: There were a cross-sectional, descriptive and analytical study with retrospective collection over a period of 5 years and 6 months, from January 1st, 2016 to June 30, 2021. RESULTS: We treated 39 patients, 33 patients were included, with an exhaustiveness of 84.6%. The mean age of the patients was 52.6 years ± 11.7. The sex-ratio was 1.06. Eight patients had risk factors. Lumbar pain and hematuria were the most frequent circumstances of discovery. The average consultation time was 8.6 months ± 1.1. The physical examination had objectified a lumbar mass in 17 patients, 9 patients had lumbar contact and the examination was normal in 13 patients. The right kidney was the most affected side with 17 patients. The mean size of the tumor was 12.2 cm ± 2.4. All patients underwent radical nephrectomy. We recorded one death intraoperatively. The histological type was clear cell renal carcinoma in 32 patients. One patient had chromophobe cell renal cell carcinoma. CONCLUSION: Kidney cancer is a rare pathology, it occurs in adults around the age of fifty. Patients consult late and locally advanced and metastasized forms are the most frequent. The histological type is dominated by clear cell renal carcinoma. KEYWORDS: Cancer; Kidney; Nephrectomy.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79583340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiotherapy of stage IVA cervical cancer in the Radiotherapy Department of the Aristide le Dantec Hospital in Dakar 达喀尔Aristide le Dantec医院放疗部对IVA期宫颈癌进行放疗

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.72

O. Siby, D. Traoré, I. Thiam, M. Mane, O. Sarr, N. Ben Amor, D. Dieng, M. Gaye, A. Dem, M. Dieng

{"title":"Radiotherapy of stage IVA cervical cancer in the Radiotherapy Department of the Aristide le Dantec Hospital in Dakar","authors":"O. Siby, D. Traoré, I. Thiam, M. Mane, O. Sarr, N. Ben Amor, D. Dieng, M. Gaye, A. Dem, M. Dieng","doi":"10.54266/ajo.2.2.72","DOIUrl":"https://doi.org/10.54266/ajo.2.2.72","url":null,"abstract":"INTRODUCTION: The management of stage IVA cervical cancer is based on radio-chemotherapy followed by utero-vaginal brachytherapy. In this study, we evaluate the results of external radiotherapy on stage IVA cervical cancer. MATERIALS AND METHODS: This was a retrospective, descriptive study. It covered all patients with stage IVA carcinoma of the cervix who received external radiotherapy at the Joliot Curie Institute of the Aristide Le Dantec Hospital from January 2018 to December 2019. RESULTS: We found 164 clinical records of patients, of which 24 patients had stage IVA, (14.3% of all cases). The average age of our patients was 51 years ± 12.13. Seventeen patients (70.9%) had an altered general condition on admission. The predominant histological type was squamous cell carcinoma found in 22 cases (91.6%). Anemia was found in 14 patients, (58.4%). Neo-adjuvant chemotherapy was performed in 21 of our patients (87.5%). Radiotherapy was exclusive in 20 patients (83.3%) and concomitant radio-chemotherapy was performed in 4 patients (16.7%). Normo-fractionated radiotherapy with curative intent was performed in 13 patients (54.2%), and hypo-fractionated radiotherapy with palliative intent was performed in the other 11 patients (45.8%). An objective response was found in 17 cases (70.8%) including 8 in patients who received hypo-fractionated radiotherapy and 9 in patients treated with normo-fractionated radiotherapy at a curative dose. Five patients (20.8%) had acute toxicity and 7 (29.2%) late toxicity. After 3 years of follow-up, 5 patients (29.2%) had loco-regional progression, 9 patients (37.5%) presented loco-regional recurrence and 4 patients (16.7%) presented distant metastases. Overall survival was 26.8% at 3 years. CONCLUSION: Normo-fractionated radiotherapy does not seem superior to palliative hypo-fractionated radiotherapy in terms of clinical response in stage IVA cervical cancer. KEYWORDS: Carcinoma; Uterine cervix; External radiotherapy.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"1043 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86469473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The fight against cancer in Africa at the end of the Covid-19 pandemic and in the era of the Ukrainian crisis 在2019冠状病毒病大流行结束和乌克兰危机时代，非洲与癌症的斗争

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.45

Sidy Ka, M. Dieng, A. Dem

引用次数: 0

Late diagnosis of breast cancer at the Yalgado Ouédraogo University Hospital (CHU/YO): Causes, therapeutic and prognostic impacts. About 70 cases 在亚尔加多乌姆达乌戈大学医院(CHU/YO)对乳腺癌的晚期诊断:病因、治疗和预后影响。约70例

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.63

M. Ilboudo, R. A. Djigemdé, P. B. Yameogo, I. Ouédraogo, N. Zongo

{"title":"Late diagnosis of breast cancer at the Yalgado Ouédraogo University Hospital (CHU/YO): Causes, therapeutic and prognostic impacts. About 70 cases","authors":"M. Ilboudo, R. A. Djigemdé, P. B. Yameogo, I. Ouédraogo, N. Zongo","doi":"10.54266/ajo.2.2.63","DOIUrl":"https://doi.org/10.54266/ajo.2.2.63","url":null,"abstract":"INTRODUCTION: Breast cancer is the first cancer of women in Burkina Faso. There remains a relatively late diagnosis and a reserved prognosis. The main aim of this study is to study the causes, therapeutic and prognostic impacts of late diagnosis of breast cancer at Yalgado Ouédraogo University Hospital. MATERIALS AND METHODS: This was a descriptive and prospective study from May 1st to October 31, 2013. The departments of surgery, gynecology and anatomy-pathology served as a framework for our study. All consenting breast cancer patients with a height greater than at least 5 cm (>T2), suspicious or metastatic satellite lymphadenopathy was included. The data analysis was done using Epi-info© software version 7.2.2.6, with the use of the Khi2, Fisher-exact and Student tests. RESULTS: We collected 70 patients with an average age of 46.1 years. In 95.7% of cases, our patients had consulted a traditional therapist or at least one medical center before being referred to the Yalgado Ouédraogo University Hospital. The consultation was less than 6 months in 52.9% of cases. Diagnostic time was statistically associated with source and monthly income with a p-value of 0.03 and 0.05 respectively. Stage III accounted for 62.8% of cases. Surgery was performed in 48.6% of cases, including 23.5% palliative surgery. Chemotherapy was neo-adjuvant in 22%, adjuvant in 48.8% and palliative in 14.6%. The average duration of follow-up was 2.7 months. We had found 20.6% of recidivism and 22% of deaths. CONCLUSION: Poverty, ignorance, socio-cultural constraints and lack of staff reduce patients' access to early diagnosis, which is responsible for expensive complex treatment and a poor prognosis. Equitable financial and geographic access will reduce diagnostic delays and mortality from breast cancer. KEYWORDS: Breast cancer; Late diagnosis; Causes; Treatment; Prognosis.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75227080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Childhood cervical cancer: a case report 儿童子宫颈癌1例

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.79

F. Cheumaga, L. Cissé, K. Ka, H. Chami, P. A. Mbaye, C. T. Mbaye, P. M. Gaye, M. Dieng

引用次数: 0

Breast metastasis of a dorsal melanoma: About one case and literature review 背侧黑色素瘤乳腺转移1例并文献复习

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.86

A. Soumaila, Adam Issa Douramane, I. Dillé, Ousmane Saadou Galadima, M. Zaki, Seydou Hamadou Abdoulay, Harouna Bonkoukou, Younsa Hama, Y. Harouna

引用次数: 0

Descriptive epidemiology of colorectal cancer in Burkina Faso 布基纳法索结直肠癌描述性流行病学研究

South African Journal of Oncology Pub Date : 2022-07-01 DOI: 10.54266/ajo.2.2.54

P. B. Yameogo, R. A. Djigemdé, M. Ilboudo, A. Ouédraogo, N. Zongo

{"title":"Descriptive epidemiology of colorectal cancer in Burkina Faso","authors":"P. B. Yameogo, R. A. Djigemdé, M. Ilboudo, A. Ouédraogo, N. Zongo","doi":"10.54266/ajo.2.2.54","DOIUrl":"https://doi.org/10.54266/ajo.2.2.54","url":null,"abstract":"OBJECTIVE: To describe the epidemiological profile of colorectal cancers in Burkina Faso. MATERIALS AND METHODS: This was a cross-sectional and descriptive study of colorectal cancers diagnosed in all anatomy and pathology laboratories in Burkina Faso from 1988 to 2018. Age, sex, nature of the specimens, histo-genetic and histological types were studied. Comparisons were possible using Student's t test and Fisher's Khi2 test. RESULTS: In 31 years, 802 colorectal cancers were diagnosed, representing a mean annual incidence of 25.9 cases ± 7.6. These cancers represented 30.9% of all digestive cancers and were therefore the 2nd most common digestive cancer. The mean age of the patients was 50 years ± 18.1. The sex-ratio was 1.2. In men, the mean age was 50 years ± 11.6 and in women 50 years ± 13. Endoscopic biopsy specimens were studied in 60.7% of cases. The cancers were located in the left colon in 44% of cases, in the right colon in 30.4% of cases and in the rectum in 25.6% of cases. Carcinomas constituted 93.5% of the histo-genetic types. Adenocarcinoma was the histological type in 77.9% of cases. CONCLUSION: The second most common digestive cancer in Burkina Faso, colorectal cancer occurs at a relatively young age. It is predominantly male. However, the average age of occurrence is identical in both sexes. Adenocarcinoma is the most frequent histological type. Access to mass screening would allow a better understanding of the frequencies. KEYWORDS: Epidemiology; Colorectal cancers; Burkina Faso.","PeriodicalId":52950,"journal":{"name":"South African Journal of Oncology","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80655822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0