IJU Case Reports最新文献

{"title":"Tailored Vascular Approach in Robot-Assisted Nephroureterectomy for a Horseshoe Kidney: A Case Report","authors":"Takanari Kambe,&nbsp;Yosuke Shimizu,&nbsp;Hajime Yoshida,&nbsp;Koken Hayashi,&nbsp;Shotaro Hatano,&nbsp;Tomoaki Okada,&nbsp;Kenji Mitsumori,&nbsp;Hiroyuki Onishi","doi":"10.1002/iju5.70212","DOIUrl":"https://doi.org/10.1002/iju5.70212","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>A horseshoe kidney is a rare congenital anomaly with complex vascular variations that increase surgical difficulty. Few reports have specifically addressed the vascular approaches in robot-assisted surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A man in his 70s was diagnosed with right ureteral urothelial carcinoma in a horseshoe kidney. Preoperative imaging revealed a short renal artery arising posterior to the isthmus, suggesting difficulty with conventional surgical approaches. Surgery was initiated in the supine position using a medial approach, similar to the medial-to-lateral dissection used for sigmoid colon mobilization, with cranial dissection along the aorta to secure the vessel and isthmus, followed by repositioning and standard robot-assisted nephroureterectomy. Intraoperative indocyanine green fluorescence was used to guide safe isthmus division. The procedure was completed safely without any perioperative complications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>A tailored approach based on detailed preoperative vascular assessment may facilitate safe and effective robot-assisted surgery in patients with horseshoe kidney and complex vascular anatomy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Utility of 68Ga-DOTATOC Positron Emission Tomography/Computed Tomography in Evaluating Metastatic Lesions of Clear Cell Renal Cell Carcinoma: A Case Report","authors":"Yuta Mine,&nbsp;Toru Sakatani,&nbsp;Sho Koyasu,&nbsp;Takashi Ogata,&nbsp;Yuki Teramoto,&nbsp;Akio Sakamoto,&nbsp;Takashi Mizowaki,&nbsp;Yuji Nakamoto,&nbsp;Takashi Kobayashi,&nbsp;Takayuki Goto","doi":"10.1002/iju5.70210","DOIUrl":"https://doi.org/10.1002/iju5.70210","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>⁶⁸Ga-DOTATOC positron emission tomography/computed tomography (PET/CT) targets somatostatin receptors (SSTRs) and is an established molecular imaging modality for neuroendocrine tumors (NETs). Although SSTR expression has been reported in renal cell carcinoma (RCC), its clinical utility remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 76-year-old woman who had undergone open partial nephrectomy for clear cell RCC (grade 2, pT1bN0M0) 3 years before developed a sternal metastasis, which was surgically resected with negative margins. Nine months later, follow-up CT revealed a soft-tissue lesion posterior to the sternum. ⁶⁸Ga-DOTATOC PET/CT showed no uptake in this lesion but intense uptake at the Th8 vertebra, indicating metastasis. After stereotactic body radiation therapy (35 Gy in five fractions), persistent uptake was observed 8 months later, suggesting residual viable tumor, which was histopathologically confirmed after resection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>⁶⁸Ga-DOTATOC PET/CT was useful in evaluating the possibility of recurrence of the soft-tissue lesion, assessing post-radiation viability, and guiding treatment in RCC.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70210","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruptured Abdominal Aortic Aneurysm as the Initial Manifestation of Undiagnosed Pheochromocytoma","authors":"Kyotaro Fukuta,&nbsp;Kohsuke Miyataka,&nbsp;Yuya Hiroshima,&nbsp;Nobuo Satake,&nbsp;Yuichiro Atagi,&nbsp;Keisuke Ozaki,&nbsp;Takeshi Nakashima,&nbsp;Ryoichi Nakanishi,&nbsp;Hirofumi Izaki,&nbsp;Junya Furukawa","doi":"10.1002/iju5.70211","DOIUrl":"https://doi.org/10.1002/iju5.70211","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Pheochromocytoma is a rare catecholamine-secreting tumor that can cause severe cardiovascular complications. Its association with ruptured abdominal aortic aneurysm is extremely rare.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 57-year-old man with no significant medical history presented with sudden abdominal pain and hemorrhagic shock. Computed tomography revealed a ruptured infrarenal abdominal aortic aneurysm, and emergency endovascular aneurysm repair was successfully performed. Preoperative imaging incidentally detected a hypervascular left adrenal mass. Although biochemical findings were borderline, ¹²³I-metaiodobenzylguanidine scintigraphy demonstrated intense uptake, leading to a diagnosis of pheochromocytoma. After appropriate α-adrenergic blockade, elective laparoscopic adrenalectomy was safely performed, and histopathology confirmed pheochromocytoma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlights the importance of considering pheochromocytoma as an underlying cause of ruptured abdominal aortic aneurysm and demonstrates that a staged strategy with emergency endovascular repair followed by definitive endocrine surgery can be safe and effective.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varicocelectomy Restores Spermatogenesis in Fontan-Associated Varicocele: A Two-Case Series","authors":"Yusuke Tominaga,&nbsp;Tomoko Kobayashi,&nbsp;Yuko Matsumoto,&nbsp;Takatoshi Moriwake,&nbsp;Nariaki Ozaki,&nbsp;Takuya Sadahira,&nbsp;Satoshi Katayama,&nbsp;Shingo Nishimura,&nbsp;Kensuke Bekku,&nbsp;Motoo Araki","doi":"10.1002/iju5.70206","DOIUrl":"https://doi.org/10.1002/iju5.70206","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Fontan circulation may cause chronic venous hypertension and predispose patients to varicocele and infertility, but the clinical significance of surgical treatment remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>We describe two patients with Fontan circulation who developed Fontan-associated varicocele (FAVC). A 42-year-old man presented with secondary infertility, bilateral varicocele, and progression to azoospermia after Fontan surgery. A 28-year-old man had asthenozoospermia, bilateral varicocele, and repeated failure of assisted reproductive technology. Both underwent bilateral microsurgical varicocelectomy with perioperative heparin bridging. Postoperative semen parameters improved in both patients, with sperm reappearing in the first case.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Varicocelectomy for FAVC may restore spermatogenesis in selected cases, but the risk of postoperative recurrence may be increased.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70206","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comments on Immediate Repair for Laceration of the Tunica Albuginea of the Corpora Cavernosa and Penile Urethral Injury Caused by Blunt Trauma to the Flaccid Penis: A Case Report","authors":"Fumito Yamabe","doi":"10.1002/iju5.70205","DOIUrl":"https://doi.org/10.1002/iju5.70205","url":null,"abstract":"<p>The authors report on a relatively rare case of blunt trauma-induced damage to the tunica albuginea of the corpora cavernosa and its immediate repair. This is a very valuable report for the management of trauma in flaccid penises.</p><p>Generally, damage to the tunica albuginea of the corpora cavernosa of the penis occurs mainly due to excessive force applied to an erect penis. Damage to the tunica albuginea of the corpus cavernosum is rare as a result of trauma to a flaccid penis [<span>1-3</span>].</p><p>Although the injury did not occur during erection, damage to the tunica albuginea and urethra was promptly diagnosed. Immediate repair of these injuries resulted in a favorable outcome. The authors also examined the appropriateness of immediate reconstructive surgery in this case. In this case, although it was a compressive blunt trauma, both urethral damage and damage to the tunica albuginea of the corpora cavernosa of the penis were present, making immediate reconstructive surgery appropriate [<span>4</span>].</p><p>Furthermore, it is interesting that the authors consider the mechanism of tunica albuginea damage in this case to be different from typical penile fractures, and to be a compression-type injury similar to a straddle-type injury [<span>4</span>].</p><p>The important message from this report is that damage to the tunica albuginea of the corpora cavernosa can occur even in cases of non-erect penile trauma. In cases of blunt trauma to a flaccid penis, few urologists consider the possibility of damage to the tunica albuginea, such as a penile fracture.</p><p>Considering the possibility of tunica albuginea damage in non-erect penile trauma during examination and testing will enable prompt treatment.</p><p>While penile fracture accompanied by bloody urethral discharge should raise suspicion of urethral injury [<span>5</span>], conversely, when examining urethral injury due to penile trauma, damage to the tunica albuginea of the corpus cavernosum should also be suspected.</p><p>One of the problems is follow-up after treatment.</p><p>Generally, long-term follow-up after treatment for penile fractures and penile trauma is often not performed due to patient-related factors. We hope for future reports regarding long-term issues with sexual and urinary function.</p><p>The author declares no conflicts of interest.</p><p>Data sharing not applicable to this article as no datasets were generated or analysed during the current study.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148173754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significant Response to Nivolumab Plus Ipilimumab in Metastatic Mucinous Tubular and Spindle Cell Carcinoma: A Case Report","authors":"Sho Shimasaki,&nbsp;Shinkuro Yamamoto,&nbsp;Mitsuko Iguchi,&nbsp;Erika Yamashita,&nbsp;Kaya Atagi,&nbsp;Yuhei Shiba,&nbsp;Satoshi Fukata,&nbsp;Hirofumi Satake,&nbsp;Takashi Karashima,&nbsp;Keiji Inoue","doi":"10.1002/iju5.70204","DOIUrl":"https://doi.org/10.1002/iju5.70204","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal cell carcinoma subtype that is typically indolent but may exhibit aggressive behavior. No standard systemic therapy has been established for metastatic MTSCC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 71-year-old woman underwent retroperitoneoscopic radical left nephrectomy for MTSCC (pT1b). Six months later, computed tomography (CT) and ¹⁸F-fluorodeoxyglucose positron emission tomography (PET)/CT revealed lung, bone, and adrenal metastases. Bone biopsy confirmed metastatic MTSCC, and the patient was classified as poor risk. Combination therapy with nivolumab and ipilimumab was initiated. After two cycles, PET/CT showed marked regression of metastatic lesions (SUV_max decreased from 21.7 to 4.3). RECIST evaluation demonstrated a partial response. Genomic profiling revealed microsatellite stability and a low tumor mutational burden, with no clinically actionable alterations identified on FoundationOne CDx. No disease progression was observed at 9 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case demonstrates the potential efficacy of combination immunotherapy in aggressive metastatic MTSCC.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148173755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adrenal Primary Ganglioneuroblastoma Presenting in Adulthood: A Case Report","authors":"Keiichiro Yasuda,&nbsp;Takuji Hayashi,&nbsp;Kentaro Takezawa,&nbsp;Taigo Kato,&nbsp;Koji Hatano,&nbsp;Yoichi Kakuta,&nbsp;Atsunari Kawashima,&nbsp;Eiichi Morii,&nbsp;Norio Nonomura","doi":"10.1002/iju5.70177","DOIUrl":"https://doi.org/10.1002/iju5.70177","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Ganglioneuroblastoma is a rare neuroblastic tumor derived from embryonic neural crest cells, composed of mature gangliocytes and immature neuroblasts. Although most neuroblastic tumors present in children and commonly involve the adrenal glands, adrenal ganglioneuroblastoma is rare in adults, with only 25 previously reported cases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 20-year-old female presented with epigastric pain, and imaging revealed a 13 cm left adrenal mass with calcification and heterogeneous enhancement. Endocrinological tests were normal, except for a mildly elevated urinary metanephrine level. Open adrenalectomy was performed, and histopathological examination confirmed a mixed-type adrenal ganglioneuroblastoma with low proliferative activity (Ki-67, &lt; 1%). Adjuvant therapy was not administered. The patient has remained recurrence-free for 39 months post-operatively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We report a rare case of primary adrenal ganglioneuroblastoma in an adult, emphasizing its diagnostic challenges, histopathological characteristics, and favorable post-operative course.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148167016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Acalculous Cholecystitis During Lenvatinib Plus Pembrolizumab Therapy for Advanced Renal Cell Carcinoma","authors":"Erika Soga,&nbsp;Go Noguchi,&nbsp;Kota Kobayashi,&nbsp;Rio Shibata,&nbsp;Ryosuke Jikuya,&nbsp;Tomoyuki Tatenuma,&nbsp;Mitsuru Komeya,&nbsp;Hiroki Ito,&nbsp;Hisashi Hasumi,&nbsp;Kazuhide Makiyama","doi":"10.1002/iju5.70203","DOIUrl":"https://doi.org/10.1002/iju5.70203","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Lenvatinib plus pembrolizumab is a standard first-line therapy for advanced renal cell carcinoma (RCC), and acute acalculous cholecystitis is a rare adverse event.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 60-year-old woman with metastatic TFE3-positive non–clear cell RCC, classified as poor risk by the International Metastatic RCC Database Consortium (IMDC) criteria, started pembrolizumab plus lenvatinib after palliative radiotherapy for cervical spine metastasis. Lenvatinib was initiated at 8 mg and escalated to 12 mg, achieving tumor shrinkage. Nine days after starting cycle 4, she developed fever and right upper quadrant pain. Computed tomography demonstrated gallbladder distension and wall thickening without gallstones, consistent with acute acalculous cholecystitis. Lenvatinib was interrupted, and intravenous piperacillin/tazobactam was administered; her symptoms improved without drainage. Lenvatinib was resumed at 8 mg with pembrolizumab, and no recurrence occurred.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Early recognition and temporary interruption of lenvatinib with antibiotics may allow cautious rechallenge.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148167086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Belzutifan for Metastatic TFE3-Rearranged Renal Cell Carcinoma With Pulmonary Metastases: A Case Report","authors":"Kazutaka Nakamura,&nbsp;Akihiro Kumono,&nbsp;Yuki Kobari,&nbsp;Atsuko Seki,&nbsp;Takayuki Nakayama,&nbsp;Hironori Fukuda,&nbsp;Kazuhiko Yoshida,&nbsp;Junpei Iizuka,&nbsp;Yoji Nagashima,&nbsp;Toshio Takagi","doi":"10.1002/iju5.70202","DOIUrl":"https://doi.org/10.1002/iju5.70202","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Belzutifan is effective in patients with previously treated advanced clear cell renal cell carcinoma. However, evidence for its use in non-clear cell renal cell carcinoma remains limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 33-year-old Japanese woman underwent total nephrectomy for a 10-cm renal tumor with lung metastases. The histological and immunohistochemical results were consistent with <i>TFE3</i>-rearranged renal cell carcinoma. She was administered belzutifan as fourth-line therapy. Her inflammatory markers normalized. After 4 weeks, computed tomography showed a decrease in the number and size of the pulmonary metastases, although the nodal lesions and local recurrence remained stable. At 12 weeks, chest radiography revealed improvement in both the bilateral nodular lesions and infiltrative opacities. No grade ≥ 3 adverse events occurred, as supportive care for anemia-related complications was provided.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Belzutifan led to radiographic improvement in pulmonary metastases and symptoms, while other lesions remained stable. This suggests its potential therapeutic use in <i>TFE3</i>-rearranged renal cell carcinoma.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70202","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148174641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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