Vaccine Research最新文献

筛选
英文 中文
Sequence Diversity of FliC Protein from Enterobacteriaceae Family to Introducing a Promising Epitope-Delivery Platform 肠杆菌科FliC蛋白序列多样性及其表位递送平台的研究
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.85
Sepideh Fereshteh, F. Badmasti
{"title":"Sequence Diversity of FliC Protein from Enterobacteriaceae Family to Introducing a Promising Epitope-Delivery Platform","authors":"Sepideh Fereshteh, F. Badmasti","doi":"10.52547/vacres.7.2.85","DOIUrl":"https://doi.org/10.52547/vacres.7.2.85","url":null,"abstract":"","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46382555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feeding Eggs from Hens Immunized with Specific KLH-Conjugated HIV Peptide Candidate Vaccines to Chicks Induces Specific Anti-HIV gp120 and gp41 Antibodies that Neutralize the Original HIV Antigens 将用特异性KLH结合HIV肽候选疫苗免疫的母鸡的蛋喂给鸡可诱导中和原始HIV抗原的特异性抗HIV gp120和gp41抗体
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.92
Justiz Vaillant, Ferrer Cosme, Fisher Smikle, O. Pérez
{"title":"Feeding Eggs from Hens Immunized with Specific KLH-Conjugated HIV Peptide Candidate Vaccines to Chicks Induces Specific Anti-HIV gp120 and gp41 Antibodies that Neutralize the Original HIV Antigens","authors":"Justiz Vaillant, Ferrer Cosme, Fisher Smikle, O. Pérez","doi":"10.52547/vacres.7.2.92","DOIUrl":"https://doi.org/10.52547/vacres.7.2.92","url":null,"abstract":"","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47861440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An Assessment of the 2017-2018 Post Measles Campaign Coverage Survey in the South-south Zone of Nigeria 尼日利亚南南区2017-2018年麻疹运动后覆盖率调查评估
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.41
O. Chime, Jennie Orji, C. Madu
{"title":"An Assessment of the 2017-2018 Post Measles Campaign Coverage Survey in the South-south Zone of Nigeria","authors":"O. Chime, Jennie Orji, C. Madu","doi":"10.52547/vacres.7.2.41","DOIUrl":"https://doi.org/10.52547/vacres.7.2.41","url":null,"abstract":"","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47931418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Well-Recognized Ability of Melatonin to Potentiate an Equilibrated Immune Response Calls for an Urgent Study about Its Use as an Adjuvant in Anti-SARS-Cov-2 Vaccines 褪黑素增强平衡免疫反应的能力已得到广泛认可,迫切需要研究其在抗sars - cov -2疫苗中作为佐剂的用途
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.97
G. Maestroni
{"title":"The Well-Recognized Ability of Melatonin to Potentiate an Equilibrated Immune Response Calls for an Urgent Study about Its Use as an Adjuvant in Anti-SARS-Cov-2 Vaccines","authors":"G. Maestroni","doi":"10.52547/vacres.7.2.97","DOIUrl":"https://doi.org/10.52547/vacres.7.2.97","url":null,"abstract":"Vaccines are a major weapon to control the present COVID-19 pandemic. To achieve this goal, vaccines should confer a robust and long-lasting immunity against SARS-Cov-2. Breakthrough infections and waning immunity are currently observed in patients that recovered from COVID-19 as well as in the vaccinated people. Therefore, a highly effective vaccine is needed to control the present and future outbreaks. Exogenous Nacetyl- 5-methoxy-tryptamine or melatonin (MLT) is well known to potentiate an effective and equilibrated immune response in a variety of situation including viral and bacterial infections and vaccines against different microbial and cancer antigens. In regard to anti- SARS-Cov-2 vaccines, beside stimulating specific IgG production as well as specific CD4+ and CD8+ T cells, exogenous MLT might also enhance specific IgA and secretory IgA in the mucosae;hence, preventing the re-infection and/or asymptomatic transmission of the virus. Thus, a study is urgently proposed to evaluate the effects of MLT administration either before or after vaccination against SARS-Cov-2 to evaluate its effect on strength, quality and duration of the immunity. Las but not least, due to its powerful antioxidant and anti-inflammatory properties, MLT administration might minimize the occurrence of adverse events after the vaccination.","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42066251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engineering and Development of VP4-VP7 Rotavirus Fusion Protein in Pichia pastoris 毕赤酵母中VP4-VP7轮状病毒融合蛋白的构建与开发
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.101
M. A. Bahnamiry, H. Kaghazian, S. D. Mousavi-Nasab, M. Aghasadeghi, G. Bahramali
{"title":"Engineering and Development of VP4-VP7 Rotavirus Fusion Protein in Pichia pastoris","authors":"M. A. Bahnamiry, H. Kaghazian, S. D. Mousavi-Nasab, M. Aghasadeghi, G. Bahramali","doi":"10.52547/vacres.7.2.101","DOIUrl":"https://doi.org/10.52547/vacres.7.2.101","url":null,"abstract":"","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42904585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patients with COVID‐19‐Associated Hematologic Abnormalities and the Potential Role of the Cytokine Storm: A Case Series Study 新冠肺炎相关血液异常患者和细胞因子风暴的潜在作用:一项病例系列研究
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.9
Ali Asadollahi-Amin, F. Ghiasvand, M. Hasibi, Simin Seyedpour, A. Barzegary, F. Ghadimi, Seyedahmad Seyedalinaghi, O. Dadras
{"title":"Patients with COVID‐19‐Associated Hematologic Abnormalities and the Potential Role of the Cytokine Storm: A Case Series Study","authors":"Ali Asadollahi-Amin, F. Ghiasvand, M. Hasibi, Simin Seyedpour, A. Barzegary, F. Ghadimi, Seyedahmad Seyedalinaghi, O. Dadras","doi":"10.52547/vacres.7.2.9","DOIUrl":"https://doi.org/10.52547/vacres.7.2.9","url":null,"abstract":"We report a case series of nine patients with confirmed coronavirus disease 2019 (COVID-19) in Tehran, Iran. This paper also reports narrative information on the signs and symptoms of the patients and discusses the potential immunologic perspective of the disease, especially with respect to the cytokine storm.","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46616777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethical Considerations and Challenges Duringthe COVID-19 Vaccine Deployment: Experiences from an Indian Perspective 新冠肺炎疫苗部署过程中的伦理思考与挑战:来自印度的经验
Vaccine Research Pub Date : 2020-12-01 DOI: 10.52547/vacres.7.2.56
Basu Saurav
{"title":"Ethical Considerations and Challenges Duringthe COVID-19 Vaccine Deployment: Experiences from an Indian Perspective","authors":"Basu Saurav","doi":"10.52547/vacres.7.2.56","DOIUrl":"https://doi.org/10.52547/vacres.7.2.56","url":null,"abstract":"Introduction: There is a continued quest towards developing protective vaccines to halt and end the global pandemic of COVID-19 with the research predominantly driven by the developed world. Induction of herd immunity requires mass vaccination, and any avoidable delays would cause enormous health and economic losses. However, developing countries will experience extensive vaccine allocation challenges due to limited indigenous manufacturing and cold chain facilities.","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46984515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Heat Shock Proteins on Delivery of HIV-1 Nef Antigen in Mammalian Cells 热休克蛋白对HIV-1 Nef抗原在哺乳动物细胞中传递的影响
Vaccine Research Pub Date : 2020-06-01 DOI: 10.29252/vacres.7.1.54
A. Milani, F. Rouhollah, Maryam Naseroleslami, A. Bolhassani
{"title":"The Effects of Heat Shock Proteins on Delivery of HIV-1 Nef Antigen in Mammalian Cells","authors":"A. Milani, F. Rouhollah, Maryam Naseroleslami, A. Bolhassani","doi":"10.29252/vacres.7.1.54","DOIUrl":"https://doi.org/10.29252/vacres.7.1.54","url":null,"abstract":". After 48 hours, their transfection efficiency was evaluated using fluorescent microscopy and flow cytometry. Results: The pEGFP-nef , - hsp27, -hsp27-nef, -hsp70 and - hsp70 - nef constructs were successfully prepared in large scale and high purity. The results of cell transfection with each construct showed that the percentages of Nef-GFP, Hsp27-GFP, Hsp27-Nef-GFP, Hsp70-GFP, Hsp70-Nef-GFP, Hsp70-GFP + Nef-GFP and GFP expression were 53.1  0.2, 64.22  0.8, 57.1  0.7, 68.8  1.0, 61.7  0.7, 77.4  1.5 and 81.8  1.8, respectively. Conclusion: These data showed that the potency of Hsp70 was more than Hsp27 for increasing Nef-GFP expression in HEK-293T cells. Moreover, the delivery of pEGFP-nef along with pEGFP-hsp70 increased the rate of GFP population in the cells as compared to that in pEGFP-hsp70-nef. These constructs will be used for development of HIV-1 DNA vaccine in animal model in near Future.","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48016767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Parent’s Knowledge on Rotavirus Diarrhea and Vaccine in Indonesia 印尼家长对轮状病毒腹泻及疫苗的认识
Vaccine Research Pub Date : 2020-06-01 DOI: 10.29252/vacres.7.1.38
Arie Dwi Pratiwi, D. Endarti, T. Andayani, S. A. Kristina
{"title":"Parent’s Knowledge on Rotavirus Diarrhea and Vaccine in Indonesia","authors":"Arie Dwi Pratiwi, D. Endarti, T. Andayani, S. A. Kristina","doi":"10.29252/vacres.7.1.38","DOIUrl":"https://doi.org/10.29252/vacres.7.1.38","url":null,"abstract":"Introduction: Parent’s knowledge on rotavirus diarrhea and vaccine might influence the decision to vaccinate a child. The purpose of this study was to examine knowledge level and to determine the factors that influence parents’ knowledge on rotavirus diarrhea and vaccine. Methods: The study applied an observational study design with a multi-center cross-sectional approach. The research instrument used a questionnaire to determine the sociodemographic variables and knowledge of respondents. Results: Data were collected from a survey of 500 parents in 5 provinces including Province of Central Kalimantan, Lampung, Central Sulawesi, West Java, and Yogyakarta in Indonesia using convenience sampling technique. Parents’ knowledge in this study was quite good with the average score of 78.2 ± 16.81. However, out of 500 respondents, only 158 (31.6%) parents knew that the rotavirus vaccine was not included in Indonesia's national health insurance program. There was a significant difference in the average of knowledge between the characteristics groups of age, education, monthly expenditure and experience of hearing diarrhea and rotavirus vaccine, vaccinating and source of disease information and vaccine (p <0.05). Conclusion: This study suggests the need of health promotion related to rotavirus diarrhea and vaccine in order to achieve equitable distribution of information and increase public knowledge to support future immunization programs. Citation: Pratiwi A D, Endarti D, Andayani T M, Kristina S A. Parent’s Knowledge on Rotavirus Diarrhea and Vaccine in Indonesia. vacres. 2020; 7 (1) :38-43. DOI: 10.29252/vacres.7.1.38","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44890095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Importance of Group 2 Innate Lymphoid Cells to Improve the Protective Immunity in Parasitic Helminth Infections 2族固有淋巴细胞对提高寄生虫感染保护性免疫的重要性
Vaccine Research Pub Date : 2020-06-01 DOI: 10.29252/vacres.7.1.50
P. Méndez-Samperio
{"title":"The Importance of Group 2 Innate Lymphoid Cells to Improve the Protective Immunity in Parasitic Helminth Infections","authors":"P. Méndez-Samperio","doi":"10.29252/vacres.7.1.50","DOIUrl":"https://doi.org/10.29252/vacres.7.1.50","url":null,"abstract":"Helminthiasis is a neglected public health challenge worldwide. The relevance of the important role of group 2 innate lymphoid cells (ILC2s) in the protection induced by type 2 immune responses against helminth infections has recently regained attention. The parasitic helminth infections remain as a major public health concern worldwide, particularly in tropical countries in several areas of Africa, Asia, and South America. It has been demonstrated in the experimental mouse models that ILC2s induce significant secretion of type 2 cytokines and develop protective immunity against parasitic helminths infections. However, the effects of helminth-induced immunity mediated by ILC2s have not yet been clearly defined. This review discusses the current status of the researches related to the evidence of ILC2s to improve the protective immunity in parasitic helminth infections and how these cells promote parasitic helminth expulsion. Citation: Méndez-Samperio P. The Importance of Group 2 Innate Lymphoid Cells to Improve the Protective Immunity in Parasitic Helminth Infections. vacres. 2020; 7 (1) :50-53. DOI: 10.29252/vacres.7.1.50","PeriodicalId":52727,"journal":{"name":"Vaccine Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45154503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信