发布求助
文献互助 智能选刊 最新文献

Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology最新文献

筛选
英文 中文
A Novel Study on the Hematological and Physiological Disturbance of Ivermectin-COVID 19 Treatment Abuse in Male Wistar Rats 滥用伊维菌素治疗对雄性Wistar大鼠血液学和生理障碍的新研究
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-07-12 DOI: 10.21608/eajbsc.2023.307035
Alaa Haroun, M. Bashandy, A. Hussein
{"title":"A Novel Study on the Hematological and Physiological Disturbance of Ivermectin-COVID 19 Treatment Abuse in Male Wistar Rats","authors":"Alaa Haroun, M. Bashandy, A. Hussein","doi":"10.21608/eajbsc.2023.307035","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.307035","url":null,"abstract":"----------------------","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78621869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flow Cytometric Analysis Outlines the Impact of Trending Anticancer Agents on Cell Regulators In Mouse Malignant Ascites 流式细胞术分析概述了趋势抗癌药物对小鼠恶性腹水细胞调节因子的影响
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-29 DOI: 10.21608/eajbsc.2023.305315
Maha M. Shouman, K. Alsolami, Heba Hossam
{"title":"Flow Cytometric Analysis Outlines the Impact of Trending Anticancer Agents on Cell Regulators In Mouse Malignant Ascites","authors":"Maha M. Shouman, K. Alsolami, Heba Hossam","doi":"10.21608/eajbsc.2023.305315","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.305315","url":null,"abstract":"Purpose : Malignant ascites is a common manifestation of advanced cancer. It conveys a poor prognosis affecting the quality of life. Treatment options include chemotherapy and simple drainage techniques for symptomatic relief. The aspect of malignant ascites in promoting metastasis and therapy resistance is crucial. However, chemotherapy resistance is manifested by the innate and/or acquired ability of cancer cells to resist the effects of chemotherapeutics. Methods : Malignant ascites were induced by intraperitoneal inoculation of EAC in mice followed by flow cytometric analysis that was used to evaluate the cell cycle phases and increased proliferation of ascites cells as well as the interpretation of the proliferation index and apoptosis percentage. In addition, the expression of p53 and p21 as cell cycle regulators were increased. Apoptosis was assessed by analysis of the pro-apoptotic Bax and the anti-apoptotic Bcl-2 expression. Results : Both acefylline and amygdalin combination with cisplatin showed a reduction in Ki-67 expression and arrested the cell cycle. Moreover, amygdalin treatment showed a significant reduction in S-phase and the proliferation index. This combination also restored the apoptotic cell’s apoptotic ability proved by the apoptosis index as well as the increased p53, p21 and Bcl-2 expression while reducing Bax expression in ascites fluid. Based on our results amygdaline showed a distinct effect associated with a significant reduction in the malignant ascites burden with markedly decreased proliferation and induced apoptosis. Conclusion : These findings provide a basis for the theory that combined chemoprevention is an effective treatment strategy that can be used along with conventional chemotherapy.","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75837732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insulin Resistance in End-Stage Renal Disease Patients: A Review 终末期肾病患者胰岛素抵抗的研究进展
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-29 DOI: 10.21608/eajbsc.2023.306499
B. Twaij, H. Al-Hakeim
{"title":"Insulin Resistance in End-Stage Renal Disease Patients: A Review","authors":"B. Twaij, H. Al-Hakeim","doi":"10.21608/eajbsc.2023.306499","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.306499","url":null,"abstract":"on","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84262320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Role of Nesfatin-1 and Myonectin as A Diagnostic Marker for Polycystic Ovary Syndrome and Also for Treatment Response with Metformin Nesfatin-1和Myonectin作为多囊卵巢综合征诊断指标及二甲双胍治疗效果的评价
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-28 DOI: 10.21608/eajbsc.2023.305089
N. Mahmood, Rafah Al-Sammarai, Rawaa Al-Fanar
{"title":"Evaluation of the Role of Nesfatin-1 and Myonectin as A Diagnostic Marker for Polycystic Ovary Syndrome and Also for Treatment Response with Metformin","authors":"N. Mahmood, Rafah Al-Sammarai, Rawaa Al-Fanar","doi":"10.21608/eajbsc.2023.305089","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.305089","url":null,"abstract":"","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"128 7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74378132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, Characterization, and Study of Antibacterial Activity of Some New Amphiphilic Sulfamethoxazole Derivatives 新型两亲性磺胺甲恶唑衍生物的合成、表征及抗菌活性研究
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-28 DOI: 10.21608/eajbsc.2023.304915
H. Chfat, E. Zimam
{"title":"Synthesis, Characterization, and Study of Antibacterial Activity of Some New Amphiphilic Sulfamethoxazole Derivatives","authors":"H. Chfat, E. Zimam","doi":"10.21608/eajbsc.2023.304915","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.304915","url":null,"abstract":"nucleus was functionalized with sodium azide to produce 4-azido-N-(5-methylisoxazol-3-yl)benzenesulfonamide. The end 1,2,3-triazoles were synthesized via a click reaction of the azide compound and triple bond derivatives that attached with alkyl chain or phenyl group in good yields. The structures of all prepared compounds were identified by using NMR and IR techniques. The synthesized compounds were screened for their in vitro antibacterial activity against one gram-positive bacteria S. aureus and one gram-negative bacteria E. coli. Among the synthesized compounds, compound 12 was found to be the most potent against staphylococcus aureus with MIC = 20 μg/mL compared with the other prepared compounds. Whereas compound 15 was found to be the most potent against Escherichia coli with MIC = 21 μg/mL compared with the other end compounds.","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78974385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, Characterization of Novel Triazin Complex, and Studying its Antimicrobial Activity 新型三嗪配合物的合成、表征及抗菌活性研究
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-24 DOI: 10.21608/eajbsc.2023.304197
Duha Mahmood, M. Kareem, Israa N. Witwit
{"title":"Synthesis, Characterization of Novel Triazin Complex, and Studying its Antimicrobial Activity","authors":"Duha Mahmood, M. Kareem, Israa N. Witwit","doi":"10.21608/eajbsc.2023.304197","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.304197","url":null,"abstract":") hours. The prepared ligand and their complex characterized by FT-IR, Mass, Elemental analyses, and conductivity then antimicrobial activity of the complex was studied against two pathogenic strains of E.coli and S. aurous at three values of concentrations of (10 ppm,20 ppm and 30 ppm by using standards by disk-diffusion method.","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80977881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adiponectin and Leptin Levels as Potential Biomarkers for Osteoporosis in Patients with Type 2 Diabetes Mellitus 脂联素和瘦素水平作为2型糖尿病患者骨质疏松症的潜在生物标志物
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-23 DOI: 10.21608/eajbsc.2023.304196
M. Hameed, Manal F. Al-Khakani
{"title":"Adiponectin and Leptin Levels as Potential Biomarkers for Osteoporosis in Patients with Type 2 Diabetes Mellitus","authors":"M. Hameed, Manal F. Al-Khakani","doi":"10.21608/eajbsc.2023.304196","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.304196","url":null,"abstract":"Osteoporosis, characterized by low bone mineral density (BMD) and increased fracture risk","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73115874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Biological Activity of Barbituric acid- linked Isatin Derivatives 巴比妥酸连接Isatin衍生物的合成及生物活性研究
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-19 DOI: 10.21608/eajbsc.2023.307820
Mohammed Abdul Shahed, A. Mageed
{"title":"Synthesis and Biological Activity of Barbituric acid- linked Isatin Derivatives","authors":"Mohammed Abdul Shahed, A. Mageed","doi":"10.21608/eajbsc.2023.307820","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.307820","url":null,"abstract":"The study focuses on the synthesis of isatin-barbituric acid compounds through a two-step process. In the first step, using mannich reaction, new derivatives of Isatin are synthesized by reacting Isatin with either barbituric acid, along with formaldehyde. This reaction results in the formation of Isatin-barbituric acid derivative. In the second step, these Isatin derivatives are further reacted with various aniline derivatives to generate new compounds containing Isatin. Spectroscopic methods including FTIR, 1 H NMR","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86601539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P32 Gene PCR Evaluation for Capripox’s Diagnostic Potential and Immunogenic Effect P32基因PCR对Capripox诊断潜力及免疫原性评价
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-13 DOI: 10.21608/eajbsc.2023.303858
Zain Alhindi, Afnan M. Shakoori
{"title":"P32 Gene PCR Evaluation for Capripox’s Diagnostic Potential and Immunogenic Effect","authors":"Zain Alhindi, Afnan M. Shakoori","doi":"10.21608/eajbsc.2023.303858","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.303858","url":null,"abstract":"Capripoxviruses are a group of extremely contagious viruses that cause substantial economic losses in livestock, especially goats and sheep. The purpose of this investigation was to determine the genetic diversity, antigenicity","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"25 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79742454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socio-Demographic and Environmental Factors Impacting Asthma Exacerbations in Children in Taif City, Saudi Arabia 影响沙特阿拉伯塔伊夫市儿童哮喘恶化的社会人口和环境因素
Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology Pub Date : 2023-06-11 DOI: 10.21608/eajbsc.2023.303806
K. Alsolami, M. Alharthi, Shahad Al-harthi, Refal Al-nemari, Jood Al-nemar, R. Al-Ghamdi, Al-Hanouf A. Al-Malki
{"title":"Socio-Demographic and Environmental Factors Impacting Asthma Exacerbations in Children in Taif City, Saudi Arabia","authors":"K. Alsolami, M. Alharthi, Shahad Al-harthi, Refal Al-nemari, Jood Al-nemar, R. Al-Ghamdi, Al-Hanouf A. Al-Malki","doi":"10.21608/eajbsc.2023.303806","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.303806","url":null,"abstract":"----------------------Keywords","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72735587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信