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Sustained and Clinically Meaningful Improvements in Moderate to Severe Pruritus Patients With PBC Treated With Seladelpar: Results From the ASSURE Study Up to 30 Months. Seladelpar治疗中至重度PBC患者瘙痒的持续和有临床意义的改善：来自ASSURE研究长达30个月的结果
Gastroenterology and Hepatology Pub Date : 2025-12-01
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引用次数: 0
Weight-Dependent and -Independent Effects of Semaglutide in Participants With MASH: Secondary Analysis of the Phase 3 ESSENCE Trial. 西马鲁肽对MASH患者体重依赖性和独立性的影响：3期ESSENCE试验的二次分析。
Gastroenterology and Hepatology Pub Date : 2025-12-01
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引用次数: 0
Volixibat Leads to Improvements in Fatigue and Sleep for Adults With PBC: Data From VANTAGE. Volixibat可以改善PBC患者的疲劳和睡眠：来自VANTAGE的数据。
Gastroenterology and Hepatology Pub Date : 2025-12-01
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引用次数: 0
Once-Monthly Efimosfermin Alfa for Up to 48 Weeks in MASH With F2/F3 Fibrosis: Results From a Phase 2, Open-Label Extension Study. 每月一次的Efimosfermin α治疗伴有F2/F3纤维化的MASH长达48周：来自2期开放标签扩展研究的结果
Gastroenterology and Hepatology Pub Date : 2025-12-01
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引用次数: 0
Highlights From the Recent AASLD AST Practice Guideline on Adult Liver Transplantation and Graft-Related Complications. 最近的AASLD AST成人肝移植和移植物相关并发症实践指南的亮点。
Gastroenterology and Hepatology Pub Date : 2025-12-01
Elizabeth Verna
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引用次数: 0
Comparison of MAESTRO-NASH and ESSENCE: Effects of Resmetirom and Semaglutide Relative to Placebo on Primary and Secondary Liver Biopsy Endpoints Using Aligned Endpoints and Statistical Methods. MAESTRO-NASH和ESSENCE的比较：使用对齐终点和统计学方法，雷美替龙和西马鲁肽相对于安慰剂对原发性和继发肝活检终点的影响。
Gastroenterology and Hepatology Pub Date : 2025-12-01
{"title":"Comparison of MAESTRO-NASH and ESSENCE: Effects of Resmetirom and Semaglutide Relative to Placebo on Primary and Secondary Liver Biopsy Endpoints Using Aligned Endpoints and Statistical Methods.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 12 Suppl 11","pages":"15-16"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12879040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Top-Line Phase 2 Results of DD01, a Dual GLP-1/Glucagon Agonist, Lead to Rapid Improvements in Liver and Metabolic Endpoints in Patients With MASLD/MASH. DD01是一种GLP-1/胰高血糖素双激动剂，在MASLD/MASH患者的肝脏和代谢终点得到快速改善。
Gastroenterology and Hepatology Pub Date : 2025-12-01
{"title":"Top-Line Phase 2 Results of DD01, a Dual GLP-1/Glucagon Agonist, Lead to Rapid Improvements in Liver and Metabolic Endpoints in Patients With MASLD/MASH.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 12 Suppl 11","pages":"13-14"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12879041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
36 Months of Treatment With Seladelpar Is Associated With Stable or Improved Liver Stiffness in Patients With PBC. PBC患者接受36个月的Seladelpar治疗后肝脏硬度稳定或改善
Gastroenterology and Hepatology Pub Date : 2025-12-01
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引用次数: 0
Impact of Linerixibat on Pharmacodynamic Biomarkers and Mediators of Cholestatic Pruritus in PBC in the Phase 3 GLISTEN Study. 利奈昔坦对PBC患者胆汁淤积性瘙痒的药效学生物标志物和介质的影响
Gastroenterology and Hepatology Pub Date : 2025-12-01
{"title":"Impact of Linerixibat on Pharmacodynamic Biomarkers and Mediators of Cholestatic Pruritus in PBC in the Phase 3 GLISTEN Study.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 12 Suppl 10","pages":"6-7"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12879065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Evolving Field of Interventional Endoscopic Ultrasound. 介入内镜超声领域的发展。
Gastroenterology and Hepatology Pub Date : 2025-12-01
Gary R Lichtenstein
{"title":"The Evolving Field of Interventional Endoscopic Ultrasound.","authors":"Gary R Lichtenstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 12","pages":"732"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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