CONTINUUM Lifelong Learning in Neurology最新文献_第8页

Key Points for Issue. 问题的关键点。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/01.CON.0001069288.54053.05

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List of Abbreviations. 缩略语列表。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/01.CON.0001069684.75134.ce

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Issue Overview. 问题概述。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/01.CON.0001069688.22753.92

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CONTRIBUTORS. 贡献者。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001478

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SELF-ASSESSMENT AND CME. 自我评估和继续教育。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001483

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Neuromodulation for Neuropathic Pain Syndromes. 神经调控治疗神经病理性疼痛综合征。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001485

Prasad Shirvalkar

{"title":"Neuromodulation for Neuropathic Pain Syndromes.","authors":"Prasad Shirvalkar","doi":"10.1212/CON.0000000000001485","DOIUrl":"10.1212/CON.0000000000001485","url":null,"abstract":"Objective: This article reviews the principles, applications, and emerging trends of neuromodulation as a therapeutic approach for managing painful neuropathic diseases. By parsing evidence for possible mechanisms of action and clinical trial outcomes for various diseases, this article focuses on five common therapy modalities: cutaneous, peripheral nerve, spinal cord, and brain stimulation, and intrathecal drug delivery.Latest developments: Recent advances in both invasive and noninvasive neuromodulation for pain have introduced personalized and closed-loop techniques, integrating real-time feedback mechanisms and combining therapies to improve physical and psychosocial function. Novel stimulation waveforms may influence distinct neural tissues to rectify pathologic pain signaling.Essential points: With appropriate patient selection, peripheral nerve stimulation or epidural stimulation of the spinal cord can provide enduring relief for a variety of chronic pain syndromes. Newer technology using high frequencies, unique waveforms, or closed-loop stimulation may have selective advantages, but our current understanding of therapy mechanisms is very poor. For certain diagnoses and patients who meet clinical criteria, neuromodulation can provide profound, long-lasting relief that significantly improves quality of life. While many therapies are supported by data from large clinical trials, there is a risk of bias as most clinical studies were funded by device manufacturers or insurance companies, which increases the importance of real-world data analysis. Emerging methods like invasive or noninvasive brain stimulation may help us dissect basic mechanisms of pain processing and hold promise for personalized therapies for refractory pain syndromes. Finally, intrathecal delivery of drugs directly to segments of the spinal cord can also modify pain signaling to provide therapy for severe pain syndromes.","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"30 5","pages":"1475-1500"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Table of Contents. 目录表。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001481

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Spine Pain. 脊椎疼痛

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001473

Vernon B Williams

{"title":"Spine Pain.","authors":"Vernon B Williams","doi":"10.1212/CON.0000000000001473","DOIUrl":"10.1212/CON.0000000000001473","url":null,"abstract":"Objective: Spine pain is one of the most common presenting concerns in health care settings. This article reviews clinical strategies for evaluating and managing patients with spine pain.Latest developments: Minimally invasive interventional procedures, virtual reality, predictive analytics, neuromodulation, and other evolving technologies are significantly impacting the management of spine pain. Advances in modern pain science have also led to effective skills and treatment strategies, including patient interviews and queries for insight regarding pain, education, and cognitive restructuring, and adjusting the timing of examination (after reeducation) and examination techniques to encourage the experience of movement in the absence of assumed tissue damage. An evolving understanding of the influence of patient-centric thoughts, framing, emotional status, and cognitive restructuring's influence on the brain's response to perceived threat are important aspects of spine pain management.Essential points: The correlation of clinical presentations with structural abnormalities is necessary but insufficient to evaluate and manage spine pain. Modern pain science acknowledges pain as a subjective experience but recognizes a critical distinction between tissue damage, nociception, and the experience of pain. What and how we communicate with patients, as well as evolving neuromodulation technologies, augment conventional approaches.","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"30 5","pages":"1344-1362"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Learning Objectives and Core Competencies. 学习目标和核心竞争力。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001482

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Postreading Self-Assessment and CME Test-Preferred Responses. 阅读后自我评估和CME测试偏好反应。

CONTINUUM Lifelong Learning in Neurology Pub Date : 2024-10-01 DOI: 10.1212/CON.0000000000001480

Nuri Jacoby, James M W Owens

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