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CONTINUUM Lifelong Learning in Neurology最新文献

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Hypersomnia.
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001725
Margaret Kay-Stacey
{"title":"Hypersomnia.","authors":"Margaret Kay-Stacey","doi":"10.1212/cont.0000000000001725","DOIUrl":"10.1212/cont.0000000000001725","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this article is to provide an overview of how to evaluate, diagnose, and manage patients with hypersomnia disorders.</p><p><strong>Latest developments: </strong>The extended-release formulation of sodium oxybate to treat narcolepsy with a dosage of once a night, rather than twice a night, was approved in 2023 for adults and in 2024 for pediatric patients aged 7 years and older by the US Food and Drug Administration (FDA). The novel pharmacokinetics of this formulation may improve medication adherence and reduce nighttime disruptions and sleep fragmentation for patients and their bed partners. Orexin receptor 2 agonists are also being investigated for the treatment of narcolepsy and idiopathic hypersomnia. CSF orexin testing can be used to diagnose narcolepsy type 1.</p><p><strong>Essential points: </strong>Patients with hypersomnia have excessive daytime sleepiness, which can be due to an underlying sleep disorder or can be secondary to another condition. Diagnostic tools are useful but imperfect. It is essential to obtain a detailed sleep history to understand how patient symptoms are affecting daily life.</p>","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1091-1116"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep-Disordered Breathing in Patients With Neuromuscular Disorders. 神经肌肉疾病患者的睡眠呼吸障碍。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001729
Brynn K Dredla
{"title":"Sleep-Disordered Breathing in Patients With Neuromuscular Disorders.","authors":"Brynn K Dredla","doi":"10.1212/cont.0000000000001729","DOIUrl":"10.1212/cont.0000000000001729","url":null,"abstract":"<p><strong>Objective: </strong>Sleep-disordered breathing is a major contributor to morbidity and mortality in individuals with neuromuscular disorders, significantly affecting quality of life. This article provides a comprehensive review of respiratory physiology in the context of neuromuscular disorders, highlights essential components of a sleep-focused clinical history, and outlines evidence-based strategies for the diagnosis and management of sleep-disordered breathing as neuromuscular conditions progress over time.</p><p><strong>Latest developments: </strong>Sleep-disordered breathing testing can be accomplished in various settings to limit barriers to the identification of disease and treatment. Noninvasive ventilation technology has progressed to be more patient centric, with variable settings to ensure patient comfort and support.</p><p><strong>Essential points: </strong>Early identification and treatment of sleep-disordered breathing in patients with neuromuscular disease can significantly improve quality of life and represent a readily modifiable factor in patient care. Noninvasive ventilation should be tailored to the individual patient's needs and comfort, with ongoing monitoring and adjustments based on specific neuromuscular diagnosis and disease progression.</p>","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1201-1219"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Learning Objectives and Core Competencies. 学习目标和核心竞争力。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001736
{"title":"Learning Objectives and Core Competencies.","authors":"","doi":"10.1212/cont.0000000000001736","DOIUrl":"https://doi.org/10.1212/cont.0000000000001736","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"978"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SELF-ASSESSMENT AND CME. 自我评估和继续教育。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001731
{"title":"SELF-ASSESSMENT AND CME.","authors":"","doi":"10.1212/cont.0000000000001731","DOIUrl":"https://doi.org/10.1212/cont.0000000000001731","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1249"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurology's Action Potential: The Importance of Physician Leadership in Health Care. 神经学的动作电位：医生领导在医疗保健中的重要性。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001765
Lyell K Jones
{"title":"Neurology's Action Potential: The Importance of Physician Leadership in Health Care.","authors":"Lyell K Jones","doi":"10.1212/cont.0000000000001765","DOIUrl":"https://doi.org/10.1212/cont.0000000000001765","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"986-987"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Key Points for Issue. 问题的关键点。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/01.cont.0001238764.68341.be
{"title":"Key Points for Issue.","authors":"","doi":"10.1212/01.cont.0001238764.68341.be","DOIUrl":"https://doi.org/10.1212/01.cont.0001238764.68341.be","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1cont000123876468341be"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postreading Self-Assessment and CME Test. 阅读后自我评估和CME测试。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001732
Joanne Lynn, James W M Owens
{"title":"Postreading Self-Assessment and CME Test.","authors":"Joanne Lynn, James W M Owens","doi":"10.1212/cont.0000000000001732","DOIUrl":"https://doi.org/10.1212/cont.0000000000001732","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1251-1261"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep in the Developing Brain. 睡眠对大脑发育的影响。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001728
Kristin Seaborg
{"title":"Sleep in the Developing Brain.","authors":"Kristin Seaborg","doi":"10.1212/cont.0000000000001728","DOIUrl":"10.1212/cont.0000000000001728","url":null,"abstract":"<p><strong>Objective: </strong>This article describes the variability of sleep needs throughout infancy and adolescence and the impact that primary or secondary changes in sleep architecture and sleep quality can have on children. It also reviews the changes in sleep as a child develops as well as the bidirectional relationship of sleep and pediatric neurodevelopmental disorders, epilepsy, and psychosocial health.</p><p><strong>Latest developments: </strong>Pediatric sleep has historically been understudied. Advances have made the quantitative study of pediatric sleep more feasible, although significant gaps remain. As early as prenatal life, sleep can affect a child's development, psychological health, and long-term sleep health. Genetic influences on circadian rhythm and brain development place many children at greater risk of sleep disorders and may one day be used to proactively screen for sleep disorders in children.</p><p><strong>Essential points: </strong>Knowledge of common pediatric sleep disorders and the influence of sleep health on the impact of neurologic conditions is essential. Every child seen in a neurology clinic should be screened for sleep disorders, especially children with neurodevelopmental differences, epilepsy, or a history of structural brain abnormalities.</p>","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1220-1238"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
List of Abbreviations. 缩略语列表。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001739
{"title":"List of Abbreviations.","authors":"","doi":"10.1212/cont.0000000000001739","DOIUrl":"https://doi.org/10.1212/cont.0000000000001739","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"101212cont0000000000001739"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postreading Self-Assessment and CME Test-Preferred Responses. 阅读后自我评估和CME测试偏好反应。
CONTINUUM Lifelong Learning in Neurology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1212/cont.0000000000001733
Joanne Lynn, James W M Owens
{"title":"Postreading Self-Assessment and CME Test-Preferred Responses.","authors":"Joanne Lynn, James W M Owens","doi":"10.1212/cont.0000000000001733","DOIUrl":"https://doi.org/10.1212/cont.0000000000001733","url":null,"abstract":"","PeriodicalId":52475,"journal":{"name":"CONTINUUM Lifelong Learning in Neurology","volume":"32 4","pages":"1262-1271"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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