European Journal of Translational and Clinical Medicine最新文献

{"title":"Clinical and demographic features of acutely hospitalised schizophrenia patients according to Toxoplasma gondii serostatus","authors":"Jakub Grabowski, P. Waszak, M. Przybylak, L. Bidzan","doi":"10.31373/ejtcm/162759","DOIUrl":"https://doi.org/10.31373/ejtcm/162759","url":null,"abstract":"Background: Few data exist concerning the clinical correlates of Toxoplasma gondii infection in persons with schizophrenia. The aim of this study was to investigate the correlation between toxoplasmosis and schizophrenia regarding the quality of life, symptoms and course of hospitalisation in patients with schizophrenia. Methods: Acutely hospitalised patients (n = 67) were examined twice during their hospital stay. Schizophrenia psychopatho - logy, quality of life, extrapyramidal symptoms and T. gondii antibody titres were assessed upon admission and at discharge. Results: Toxo-IgG (+) patients (59.7%) were older, less educated, more obese and less eager to undertake psychotherapy. Female gender and higher fertility were dominant in this group with abnormal involuntary move - ments more commonly observed. Lower antipsychotic drug doses and monotherapy were used more frequently for Toxo-IgG (+) patients. Lower education (OR 2.41, 95% CI 1.21-4.79) was the most important factor associated with higher likelihood of IgG seropositivity. High levels of Toxo-IgM antibodies correlated with lower quality of life (r = -0.37; p = 0.02) and more severe positive (r = 0.40; p = 0.01) and focal (r = 0.32; p = 0.04) schizophrenia symp - toms. Conclusions: Toxoplasmosis is more common in older, obese women with lower education. Recent infection is linked to more severe schizophrenia symptoms. Patients with toxoplasmosis history were given less medication.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46842662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Ukrainian refugee crisis: its ethical aspects and challenges for the Polish healthcare system – a descriptive review","authors":"Kinga Kolińska, Anna Paprocka-Lipińska, M. Koliński","doi":"10.31373/ejtcm/162233","DOIUrl":"https://doi.org/10.31373/ejtcm/162233","url":null,"abstract":"Since the start of the Russian Invasion of Ukraine on 24.02.2022, millions of people (mostly women and children) have fled Ukraine. Majority of them fled to Poland and providing adequate medical care for the massive influx of refugees is a considerable challenge for the Polish healthcare system, already burdened by the COVID-19 pandemic and staff shortages. The purpose of this study was to identify: the potential health problems of the incoming population, the legal and ethical aspects of the refugee crisis and its implications on public health. Combining the current data with previous research on refugee crises reveals a set of issues that need to be addressed. Ensuring continuity of chronic disease treatment, mental health, the risk of spreading vaccinable preventable diseases, high rates of tuberculosis, HIV and the ongoing COVID-19 pandemic are among the main concerns. In the near future, answers will have to be found to the emerging ethical questions of equal, safe ac - cess to care, implications of the language barrier, immunisation coverage, medical staff shortages, and existing legal and ethical regulations. As the emergency responses are addressed, the hosting countries need to prepare long-term resolutions.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45062250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant Pleural Mesothelioma: A Rare Case Report","authors":"Benita Soundar Raj, Mohamed Sulaiman G, Monika Peter, Mousigan M.V","doi":"10.24018/clinicmed.2023.4.2.239","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.2.239","url":null,"abstract":"Malignant pleural mesothelioma (MPM) is a rare and extremely aggressive intrathoracic neoplasm that emerges from the mesothelial cells that line the ribs and the membrane that envelopes the lungs. We present the case of a 68-year-old male with complaints of breathlessness and fatigue. He had no history of exposure to asbestos and no association with familial exposure either. He was evaluated with a PET-CT scan, pleural cytology, and immunohistochemistry and was diagnosed with Malignant Pleural Mesothelioma. The patient was managed with chemotherapy, radiotherapy, and palliative care. A detailed report of malignant pleural mesothelioma was presented in this study.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78879168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant cell tumor of tendon sheath in the pediatric population – review","authors":"Katarzyna Kopcik, A. Koberling, J. Koper, Magda Bichalska-Lach, M. Rudzki, D. Waniczek","doi":"10.31373/ejtcm/162882","DOIUrl":"https://doi.org/10.31373/ejtcm/162882","url":null,"abstract":"Giant cell tumor of tendon sheath is a rare and benign soft-tissue tumor, which is even less common in the pe - diatric population. It may be connected with chromosomal translocations, often the 1p11-13. Symptoms include pain, swelling, palpable mass or limited range of motion. Magnetic resonance is the diagnostic method of choice. Histopathological image obtained from biopsy should be also evaluated. The gold standard of treatment is total surgical resection of the tumor, as incomplete excision may result in recurrence. Physicians should also consider the future function of the affected joint or limb. Our aim was to review the available literature about GCTTS in the pediatric population","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42772916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is medicine ready for ChatGPT – why not just ask ChatGPT?","authors":"A. Rodigin","doi":"10.31373/ejtcm/162647","DOIUrl":"https://doi.org/10.31373/ejtcm/162647","url":null,"abstract":"As it has often happened in the past, medicine may find itself in captivity of “pioneering and promising” technolo - gical trends and fashions. Indeed, while ChatGPT and its progeny may evolve and “become ready for primetime,” we may not – not now","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42433884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of diabetes-related complications and the cost of diabetes in Poland. The methodology and the research sample used in Economedica DM-PL Survey","authors":"Stefan Bogusławski, A. Wojciechowska, A. Smaga, K. Strojek, K. Wrobel, B. Wojtyniak, G. Juszczyk, M. Czech, T. Zdrojewski","doi":"10.31373/ejtcm/162189","DOIUrl":"https://doi.org/10.31373/ejtcm/162189","url":null,"abstract":"Background: Knowledge about diabetes mellitus (DM)-related complications, the direct and indirect costs incur - red by patients with DM is still insufficient in Poland. Economedica DM-PL ( Economedica ) survey was a cross--sectional observational study that aimed to assess these issues. Material and methods: The survey was carried out in 2016 on a representative sample of 2032 diabetic patients recruited by 195 general practitioners (GP) and 48 diabetologists (D) randomly selected from the national registry of physicians. Each GP and D recruited 8 to 10 patients with DM according to the specified protocol. The study included 1938 medical questionnaires (comple - ted by the GPs and Ds), 1938 questionnaires about costs (completed by the patients) and 1532 treatment adhe - rence questionnaires. Results: The Economedica survey provided new insights into DM epidemiological and cost data. 70% of patients with type-1 DM were diagnosed with the disease before the age of 40. For 76% patients with type-2 DM, it was diagnosed after the age of 50. The average monthly out-of-pocket medical costs for DM patients in 2016 reached 66.2 EUR, while their non-medical costs were 36.8 EUR. Conclusions: The methodology applied in our study proved useful for providing new dimensions of DM epidemiological and cost data in Poland.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48600365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Practice of Healthcare Waste Management among Healthcare Workers at Yusuf Dantsoho Memorial Hospital (YDMH), Kaduna, Nigeria","authors":"S. Musa, A. Aliyu, A. Ikwuka, Francis Chigozie Udeh","doi":"10.24018/clinicmed.2023.4.2.249","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.2.249","url":null,"abstract":"\u0000Introduction: Hospital waste has been reported to be poorly handled and managed by the hospital staff and administration respectively, leading to environmental and health consequences within hospitals and to the population outside health facilities.\u0000\u0000\u0000Aim: To assess the knowledge and practice of healthcare waste management (HCWM) among healthcare workers at Yusuf Dantsoho Memorial Hospital (YDMH), Kaduna, Nigeria.\u0000\u0000\u0000Materials and Methods: A cross-sectional study was conducted amongst doctors, nurses, medical laboratory scientists and technicians, ward attendants, and cleaners at YDMH. A simple random sampling technique was used to select the study unit. A total of 73 health workers consented to an interview. The data was obtained through the administration of questionnaires on the knowledge of health workers while the practice was assessed by direct observation using a checklist. Data were collected and compiled using Microsoft Excel and analysed using IBM, SPSS version 23.0.\u0000\u0000\u0000Results: There were 39 (53.4%) males and 34 (46.4%) females in this study. The average age of participants was 36.8 ± 8.3 years. The study revealed good knowledge of waste management amongst nurses (88.18%), doctors (86.68%), medical laboratory scientists and technicians (77.48%), ward attendants (19.1%), and cleaners (17.5%), respectively. In practice, all the wards and departments observed do not have (0%) colour-coded plastic bags on their waste bins, with only 70% having their waste bins covered, 30% having posters to guide waste users displayed near the waste bins, and 0% waste treatment before disposal practice. The health facility’s method of final waste disposal is not in line with best practices.\u0000\u0000\u0000Conclusion: This study highlights the discrepancy and inadequacies of knowledge and practice of proper healthcare waste management among healthcare workers. The healthcare workers with adequate knowledge were the nurses, doctors, and medical laboratory scientists and technicians while the least knowledge was found amongst ward attendants and cleaners. The practice of healthcare waste management was poor across all professions. This calls for the need to train and retrain all health workers with emphasis on the ward attendants and cleaners. Also, there is a need for the provision of colour-coded waste bin liners in all wards and departments which should be adequately budgeted for by the management.\u0000","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88734220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Del Nido cardioplegia versus other contemporary solutions for myocardial protection – a literature review","authors":"B. Brzeska, W. Karolak, Paweł Żelechowski, Andrzej Łoś, Nikodem Ulatowski, R. Pawlaczyk","doi":"10.31373/ejtcm/163317","DOIUrl":"https://doi.org/10.31373/ejtcm/163317","url":null,"abstract":"Myocardial protection is one of the most important factors ensuring patient safety during cardiac surgery with the application of cardiopulmonary bypass. Infusion of cardioplegic solution into the coronary circulation pro - tects the heart and provides a standstill operating field for the surgeon. Cold blood cardioplegia and crystalloid cardioplegia are the two main types of solutions with a long history of use and a large amount of research proving their efficacy and safety. Relatively new del Nido cardioplegia seems to be an interesting alternative. We revie - wed the literature comparing del Nido cardioplegia with two other types of cardioplegic solutions. We took into consideration many different clinical and biochemical aspects may indicate the quality of cardioprotection.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42755131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of obesity diagnosed by different diagnostic criteria in Polish social-media users","authors":"G. Samek, A. Szulc, J. Dardzińska","doi":"10.31373/ejtcm/162572","DOIUrl":"https://doi.org/10.31373/ejtcm/162572","url":null,"abstract":"Background: In 2020, Polish experts recommended the use of the guidelines of the American Association of Clini - cal Endocrinologist and the American College of Endocrinology (AACE/ACE) in the diagnosis of obesity instead of the 1998 WHO criteria. Thus, obesity can be also diagnosed in patients with BMI 25.0-29.9 if there are complica - tions related to the excess body weight including infertility and hypogonadism, asthma, sleep apnea, gastroeso - phageal reflux disease, stress urinary incontinence, osteoarthritis and depression. Material and methods: The aim of the study was to assess the prevalence of obesity diagnosed according to the new criteria in the group of Polish social media users. Results: Among the respondents, 9.7% had a BMI below 18.5 kg/m 2 , 63.9% declared normal BMI, and 18.8% had BMI 25.0-29.9 kg/m 2 . The value of BMI ≥ 30 kg/m 2 , equivalent to the diagnosis of obesity according to WHO, was found in 7.6% of the respondents. For comparison, the prevalence of obesity according to the AACE/ACE criteria was more than twice as high (17.2%, p < 0.05). Conclusions: Concluding, according to the new criteria, more respondents were diagnosed with obesity compared to WHO criteria. The results of the study indicate that the application of the new diagnostic criteria may enable earlier diagnosis and thus earlier treatment of obesity.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43768750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for a scoping review of fecal microbiota transplantation from patients into animals","authors":"Jakub Ruszkowski, Z. Kachlik, M. Wałaszek, D. Storman, A. Dębska-Ślizień","doi":"10.31373/ejtcm/161737","DOIUrl":"https://doi.org/10.31373/ejtcm/161737","url":null,"abstract":"Microbiota studies have uncovered numerous associations between human gut microbes and health-related outcomes. However, since most of these correlations were observed in cross-sectional studies, the causal infe - rence is limited. The causal contribution of microbiota can be evidenced through disease induction or exacerba - tion in animal models after fecal microbiota transplantation (FMT) from patients. In this article we present a protocol for a scoping review on the subject of FMT from humans to animals. Besides assessing how the published studies were conducted, in that scoping review we aim to find out whether enough literature exists to conduct a systematic review of the evidence for microbiota participation in the pathophysio - logy of any human non-infectious disease or phenotypic trait. We will conduct searches on the Web of Science platform and databases: MEDLINE, Scopus, EMBASE. Citation chasing of included studies will be done. We will include studies assessing the effects of FMT collected from people with certain medical conditions on animals. Studies that recruited only healthy humans or used other animals as donors will be excluded. The results of this literature search will be tabulated and discussed. Moreover, we will provide a short list of human non-infectious diseases or traits with the highest number of FMT patient-to-animal studies.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47541483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}