CVIR Endovascular最新文献

筛选
英文 中文
Intravascular ultrasound-guided retrieval of a fish bone embedded in the inferior vena cava: a case report. 超声血管内引导下下腔静脉内埋鱼骨取出一例报告。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-29 DOI: 10.1186/s42155-026-00778-5
Leslye F Conde, Mario Matute-González, Arantxa Gelabert, Adriana Sueiras, Marta Barrufet
{"title":"Intravascular ultrasound-guided retrieval of a fish bone embedded in the inferior vena cava: a case report.","authors":"Leslye F Conde, Mario Matute-González, Arantxa Gelabert, Adriana Sueiras, Marta Barrufet","doi":"10.1186/s42155-026-00778-5","DOIUrl":"10.1186/s42155-026-00778-5","url":null,"abstract":"<p><strong>Background: </strong>Intravascular migration of ingested fish bones is an exceptionally rare complication that may result in thrombosis or embolic events. We report a case of inferior vena cava thrombosis caused by fish bone migration successfully managed by IVUS-guided endovascular retrieval.</p><p><strong>Case presentation: </strong>A 70-year-old woman with stage IV cholangiocarcinoma presented with night sweats, chills, and abdominal pain. Contrast-enhanced CT demonstrated focal inferior vena cava thrombosis containing a linear hyperdense foreign body extending into a renal vein, associated with inflammatory changes adjacent to the duodenum and segmental pulmonary embolism. Fluoroscopic visualization was limited. IVUS enabled precise localization of the foreign body within the thrombus. After unsuccessful snare retrieval attempts, the fish bone was successfully removed using rat-tooth forceps under combined fluoroscopic and real-time IVUS guidance. The patient was discharged asymptomatic on oral anticoagulation planned for 6 months. One-month follow-up CT confirmed complete resolution of inferior vena cava thrombosis and inflammatory changes, with no need for further foreign body-related intervention.</p><p><strong>Conclusions: </strong>IVUS facilitates retrieval of intravascular foreign bodies embedded within venous thrombus, particularly when fluoroscopic visualization is poor, and can assist in selecting alternative retrieval strategies when conventional snares fail.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13624244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost analysis of venous stent reconstruction in the treatment of chronic lower extremity venous occlusive disease : Cost analysis of venous stent reconstruction for chronic lower extremity venous occlusive disease. 慢性下肢静脉闭塞性疾病静脉支架重建的成本分析:慢性下肢静脉闭塞性疾病静脉支架重建的成本分析。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-23 DOI: 10.1186/s42155-026-00648-0
Samir S Jambhekar, Jacob J Bundy, Spencer B Lewis, Ravi N Srinivasa, Anthony N Hage, Eric J Monroe, Jeffrey Forris Beecham Chick, David S Shin, Matthew Abad-Santos, Mina S Makary
{"title":"Cost analysis of venous stent reconstruction in the treatment of chronic lower extremity venous occlusive disease : Cost analysis of venous stent reconstruction for chronic lower extremity venous occlusive disease.","authors":"Samir S Jambhekar, Jacob J Bundy, Spencer B Lewis, Ravi N Srinivasa, Anthony N Hage, Eric J Monroe, Jeffrey Forris Beecham Chick, David S Shin, Matthew Abad-Santos, Mina S Makary","doi":"10.1186/s42155-026-00648-0","DOIUrl":"10.1186/s42155-026-00648-0","url":null,"abstract":"","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149032055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antioxidant premedication reduces mitochondrial and nuclear DNA damage repair in interventional physicians performing X-ray-guided angiography procedures: a pilot clinical intervention study. 抗氧化剂预用药减少介入医生进行x线引导血管造影过程中线粒体和核DNA损伤修复:一项试点临床干预研究
IF 2.1
CVIR Endovascular Pub Date : 2026-09-22 DOI: 10.1186/s42155-026-00777-6
Kieran Murphy, Thomas Lindsay, Kongteng Tan, Sean Lau, Gavin Elias, Kieran Luke, Josh Nederveen, Donald Xhuti, Mahek Minhas, Benjamin Lok, Shusen Zhu, Gaylene Pron, Mark Tarnopolsky
{"title":"Antioxidant premedication reduces mitochondrial and nuclear DNA damage repair in interventional physicians performing X-ray-guided angiography procedures: a pilot clinical intervention study.","authors":"Kieran Murphy, Thomas Lindsay, Kongteng Tan, Sean Lau, Gavin Elias, Kieran Luke, Josh Nederveen, Donald Xhuti, Mahek Minhas, Benjamin Lok, Shusen Zhu, Gaylene Pron, Mark Tarnopolsky","doi":"10.1186/s42155-026-00777-6","DOIUrl":"10.1186/s42155-026-00777-6","url":null,"abstract":"<p><strong>Background: </strong>To examine effects of naturally occurring antioxidants on DNA damage repair acute responses of ionizing radiation sustained by interventional physicians during angiography.</p><p><strong>Methods: </strong>The study cohort included 20 interventional physicians (19 males, 1 female; mean age: 45.4 ± 13.2 years) performing angiography fluoroscopically guided procedures. Participants were allocated to a treatment group receiving oral antioxidants (N = 10/group) before starting day cases or to an untreated control group performing procedures without antioxidants (N = 10/group). mRNA biomarkers of nuclear and mitochondrial DNA injury repair response in peripheral blood lymphocytes were assessed before and after workday.</p><p><strong>Results: </strong>Baseline DNA repair biomarkers and procedural fluoroscopic exposures were similar between the study groups. Individual pre-post changes in MRNA levels were not significant for any biomarkers in the antioxidant-treated group but were significantly increased in the untreated control group for P53 (P = 0.006), NF-κB (P = 0.002), and COX4i1 (P = 0.004). Between-group differences in post-exposure gene expression were significantly (P = 0.024) higher with P53 being 78% higher in the untreated versus the treated group and COX4i1 levels also significantly (P = 0.028) higher by 46% in the untreated group. Absolute change in the STAT3 mRNA level was higher by 54% in the untreated group but between-group difference was not significant (P = 0.066). There was a lower burden of NF-κB mRNA levels of inflammation in the treatment than the untreated group (18 ± 8% versus 60 ± 15%) with significant between-group difference (P = 0.020).</p><p><strong>Conclusions: </strong>Significant elevations in peripheral blood lymphocytes of mRNA biomarkers of nuclear and mitochondrial DNA injury repair response occurred in untreated interventional physicians exposed to ionizing radiation during fluoroscopically guided interventions. In physicians pretreated with a novel antioxidant formulation, biomarkers of DNA repair responses were significantly attenuated suggesting a decreased acute IR-induced oxidative stress-mediated DNA damage response.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central gland detachment following prostate artery embolization: incidence, risk factors and clinical outcomes. 前列腺动脉栓塞后中央腺体脱离:发病率、危险因素和临床结果。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-19 DOI: 10.1186/s42155-026-00774-9
Fergus O'Herlihy, Sean Collins, Matthew Laffey, Kiaran O'Malley, Richard E Power, Cormac Farrelly
{"title":"Central gland detachment following prostate artery embolization: incidence, risk factors and clinical outcomes.","authors":"Fergus O'Herlihy, Sean Collins, Matthew Laffey, Kiaran O'Malley, Richard E Power, Cormac Farrelly","doi":"10.1186/s42155-026-00774-9","DOIUrl":"10.1186/s42155-026-00774-9","url":null,"abstract":"<p><strong>Background: </strong>Central gland detachment (CGD) is a potential complication following prostate artery embolisation (PAE). There is limited information regarding its incidence, associated risk factors, and voiding and ejaculatory function after CGD.</p><p><strong>Methods: </strong>Sixty-five consecutive patients undergoing PAE in a single institution were included in this retrospective cohort study. Baseline demographics, radiologic, procedural and clinical outcome data were gathered for all patients. CGD was diagnosed following clinical review and confirmed via cystoscopy or MRI as required.</p><p><strong>Results: </strong>Six out of 65 (9.2%) patients undergoing PAE developed CGD. Mean baseline prostate volume was 150 mL. CGD occurred more frequently among patients with prostate volume > 150 mL than among those with volume ≤ 150 mL (19.2% vs. 2.6%, p = 0.03). Embolisation was performed with particles < 300 μm in 11/65 cases; CGD incidence was numerically higher among patients treated with particles < 300 μm than with particles > 300 μm (27.3 vs. 5.6%, p = 0.056), although this association did not reach statistical significance. 4/6 patients required cystoscopic removal of sloughed tissue. After resolution of the acute CGD episode, mean International Prostate Symptoms Scores (IPSS) and quality of life due to urinary symptoms (QOL) scores improved from 22 to 2.3 and from 5.3 to 0.5 respectively. In those with preserved ejaculatory function at baseline, 3/4 CGD patients developed new retrograde ejaculation.</p><p><strong>Conclusion: </strong>Central gland detachment is an uncommon but clinically significant complication of PAE. Severe prostatomegaly may be associated with CGD, and cases can occur despite use of medium-sized particles (> 300 μm). Long-term voiding outcomes are generally favourable, but new ejaculatory dysfunction can occur.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When should clinical practice guidelines change? A critical appraisal of the ESVS focused update on paclitaxel-coated devices after SWEDEPAD 2. 临床实践指南何时应该改变?对ESVS的关键评估集中在SWEDEPAD 2后紫杉醇涂层器械的更新。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-16 DOI: 10.1186/s42155-026-00775-8
Fabrizio Fanelli, Andrew Holden, Maria Antonella Ruffino, Stefan Muller-Hulsbeck, Patrick Haage, Mohamed Hamady, Romaric Loffroy, Hicham Kobeiter, Florian Wolf, Gerard O'Sullivan, Lakshmi Ratnam, Robert Morgan
{"title":"When should clinical practice guidelines change? A critical appraisal of the ESVS focused update on paclitaxel-coated devices after SWEDEPAD 2.","authors":"Fabrizio Fanelli, Andrew Holden, Maria Antonella Ruffino, Stefan Muller-Hulsbeck, Patrick Haage, Mohamed Hamady, Romaric Loffroy, Hicham Kobeiter, Florian Wolf, Gerard O'Sullivan, Lakshmi Ratnam, Robert Morgan","doi":"10.1186/s42155-026-00775-8","DOIUrl":"10.1186/s42155-026-00775-8","url":null,"abstract":"","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13582715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-arterial lidocaine as a pain management strategy for uterine artery embolisation: a systematic review and meta-analysis. 动脉内利多卡因作为子宫动脉栓塞的疼痛管理策略:系统回顾和荟萃分析。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-16 DOI: 10.1186/s42155-026-00771-y
Tarun Haridasan, Abena Kena, Larry Nguyen, Kiat Tsong Tan
{"title":"Intra-arterial lidocaine as a pain management strategy for uterine artery embolisation: a systematic review and meta-analysis.","authors":"Tarun Haridasan, Abena Kena, Larry Nguyen, Kiat Tsong Tan","doi":"10.1186/s42155-026-00771-y","DOIUrl":"10.1186/s42155-026-00771-y","url":null,"abstract":"<p><p>Post-procedural pain remains a significant challenge following uterine artery embolisation (UAE) and intra-arterial lidocaine (IAL) has emerged as a potential adjunctive analgesic. This systematic review and meta-analysis evaluated the efficacy and safety of IAL during UAE. MEDLINE, Embase, and the Cochrane Library were searched from inception to June 2026, identifying eight studies including 692 patients. IAL significantly reduced pain at 4 h post-procedure and lowered the maximum pain experienced within the first 24 h. However, there were no significant differences in pain immediately after the procedure, at 7 or 24 h, opioid consumption, or inflammatory markers. Serious adverse events were uncommon. These findings suggest that IAL provides meaningful early pain relief and may serve as a safe adjunct in pain management for UAE. Systematic review registration PROSPERO CRD420261428710.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13582736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique. 匿名汇合处的覆盖血管内重建(CERAC):描述保留汇合处血管内技术的技术说明。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-15 DOI: 10.1186/s42155-026-00765-w
Riccardo Corti, Ludovico Ambrosi, Nicola Cionfoli, Mauro Antonio D'Agostino, Pietro Quaretti, Antonio Bozzani
{"title":"Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique.","authors":"Riccardo Corti, Ludovico Ambrosi, Nicola Cionfoli, Mauro Antonio D'Agostino, Pietro Quaretti, Antonio Bozzani","doi":"10.1186/s42155-026-00765-w","DOIUrl":"10.1186/s42155-026-00765-w","url":null,"abstract":"<p><strong>Introduction: </strong>Endovascular therapy is the first-line treatment for superior vena cava syndrome (SVCS), yet the optimal strategy for lesions involving the brachiocephalic vein confluence remains debated. We describe a technique for anatomical bilateral reconstruction of the anonymous confluence using covered stents, called Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC).</p><p><strong>Materials and methods: </strong>All patients treated for SVCS between September 2024 and December 2025 were reviewed. CERAC was selectively applied based on anatomical and clinical considerations. Procedural characteristics, technical success, complications, and follow-up patency were assessed.</p><p><strong>Results: </strong>Three out of ten patients who underwent endovascular treatment for SVCS at our institution were treated using the CERAC technique. Indications included preservation of bilateral venous access in young patients with potentially treatable malignancy (n = 2) and emergency central venous decompression (n = 1). Technical success was achieved in all cases, with restoration of patency of both brachiocephalic veins and the superior vena cava. Mean fluoroscopy time was 30.6 min. No immediate complications occurred. Primary stent patency was maintained during available follow-up (29-301 days; median 149 days).</p><p><strong>Discussion: </strong>CERAC enables confluence-preserving bilateral reconstruction while minimizing stent overlap and maintaining favourable luminal geometry. Inspired by the Covered Endovascular Reconstruction of the Aortic Bifurcation, CERAC represents, to our knowledge, the first description of a fully covered, confluence-preserving reconstruction in this anatomical setting.</p><p><strong>Conclusion: </strong>CERAC is a feasible endovascular option for selected SVCS cases involving the brachiocephalic confluence. Further studies are needed to evaluate long-term outcomes and to better define appropriate indications.</p><p><strong>Level of evidence: </strong>Level V.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13578196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multistage preclinical evaluation of a retrievable 3 T MR-resonant inferior vena cava filter and snare loop for MRI-guided interventions. 可回收的3t磁共振下腔静脉过滤器和圈套环用于mri引导干预的多阶段临床前评估。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-14 DOI: 10.1186/s42155-026-00770-z
Denis Gholami Bajestani, C Martin Reich, Jan Birkigt, Christina Mulik, Johannes Kauffold, Haukur Lindberg Sigmarsson, Lisa Wahl, Michael Schmid, Senta Schauer, Thies Jochimsen, Bernhard Sattler, Osama Sabri, Erwin Immel, Andreas Melzer
{"title":"Multistage preclinical evaluation of a retrievable 3 T MR-resonant inferior vena cava filter and snare loop for MRI-guided interventions.","authors":"Denis Gholami Bajestani, C Martin Reich, Jan Birkigt, Christina Mulik, Johannes Kauffold, Haukur Lindberg Sigmarsson, Lisa Wahl, Michael Schmid, Senta Schauer, Thies Jochimsen, Bernhard Sattler, Osama Sabri, Erwin Immel, Andreas Melzer","doi":"10.1186/s42155-026-00770-z","DOIUrl":"10.1186/s42155-026-00770-z","url":null,"abstract":"<p><strong>Background: </strong>Fluoroscopy-guided inferior vena cava (IVC) filter implantation and retrieval involve ionizing radiation and iodinated contrast agents. MRI-guided interventions may provide a radiation-free alternative with direct visualization of filter position and hook accessibility. This study evaluated the feasibility of MRI-guided implantation and snare loop (SNL)-assisted retrieval of a dedicated MR-resonant IVC filter at 3 T.</p><p><strong>Methods: </strong>MR-resonant devices were assessed in a three-stage protocol. Device visibility was investigated in a saline phantom using balanced steady-state free precession (bSSFP) imaging at 3 T with the IVC filter oriented parallel to the main magnetic field B<sub>0</sub> and assessed at different longitudinal-axis rotations and flip angles. MRI-guided IVC filter implantation was performed in a polymer-based vessel phantom. Finally, MRI-guided IVC filter implantation and SNL-assisted retrieval were performed in porcine models (n = 5).</p><p><strong>Results: </strong>MR-resonant signal enhancement enabled reliable visualization of the IVC filter in phantom and in vivo experiments. Eight filters were successfully implanted in five animals, and SNL-assisted retrieval followed by re-implantation was achieved in all retrieval attempts (3/3). Quantitative signal analysis of the saline phantom experiments demonstrated significant effects of flip angle (p < 0.001), rotation angle (p < 0.001), and filter diameter (p = 0.032) on normalized signal intensity, with the strongest signal enhancement observed at a flip angle of 10°.</p><p><strong>Conclusions: </strong>MRI-guided implantation and SNL-assisted retrieval of an MR-resonant IVC filter at 3 T demonstrated feasibility within a multistage preclinical workflow. Phantom and in vivo experiments showed reliable visualization and procedural guidance, supporting further development toward clinically applicable MRI-guided caval interventions.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13575070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148972326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physician-modified endografts using an endoskeleton ePTFE platform for complex aortic aneurysms requiring a single fenestration: a proof-of-concept study. 使用内骨骼ePTFE平台的医师改良内移植物治疗需要单个开窗的复杂主动脉瘤:一项概念验证研究。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-09 DOI: 10.1186/s42155-026-00753-0
Kenjiro Kaneko, Takao Ohki, Eisaku Ito
{"title":"Physician-modified endografts using an endoskeleton ePTFE platform for complex aortic aneurysms requiring a single fenestration: a proof-of-concept study.","authors":"Kenjiro Kaneko, Takao Ohki, Eisaku Ito","doi":"10.1186/s42155-026-00753-0","DOIUrl":"10.1186/s42155-026-00753-0","url":null,"abstract":"<p><strong>Background: </strong>Endovascular interventions for complex aortic aneurysms-including juxtarenal abdominal aortic (JAAA), pararenal abdominal aortic (PRAAA), and thoracoabdominal aortic (TAAA) aneurysms-face inherent limitations, such as manufacturing delays and anatomical restrictions. In Japan, where commercial off-the-shelf branched or fenestrated devices remain limited, physician-modified endografts (PMEGs) represent a crucial practical alternative. Conventional polyester-based PMEGs, however, pose challenges regarding manual resheathing and fenestration site fragility. This study evaluated the safety and early- to mid-term clinical outcomes of PMEGs constructed using the endoskeleton-based, expanded polytetrafluoroethylene (ePTFE)-covered AFX VELA platform.</p><p><strong>Methods: </strong>This retrospective study included four high-risk patients with complex aortic aneurysms requiring a single fenestration. All were unsuitable for open surgical repair (OSR), standard endovascular aneurysm repair (EVAR), or chimney endovascular aneurysm repair (ChEVAR) due to an infrarenal neck length (IRL) < 2 mm. Fenestrations were created via sharp ePTFE incision and reinforced with an expansile hydrogel coil. Following manual resheathing without dedicated crimping tools, target vessel cannulation and bridging stent reconstruction were performed. Endpoints included technical success, 30-day major adverse events (MAEs), target vessel patency, endoleaks, sac diameter changes, and reinterventions.</p><p><strong>Results: </strong>The cohort (two men, two women; mean age, 73.0 years) presented with saccular aneurysms (one JAAA, two PRAAAs, and one Crawford type V TAAA). The mean maximum diameter was 54.3 mm, and all had an IRL of 0 mm. Technical success was 100%, with zero 30-day mortalities or MAEs. Over a 31.5-month mean follow-up, primary target vessel patency remained 100%, without endoleaks or required reinterventions. Aneurysm sac diameter regressed by 5 mm in two patients and remained stable in two. No aortic-related mortalities occurred.</p><p><strong>Conclusions: </strong>This proof-of-concept study is the first to describe AFX VELA-based PMEGs and shows that the technique is feasible in carefully selected patients with complex aortic aneurysms. The procedure does not require dedicated crimping tools or complex resheathing maneuvers, whereas its mid- to long-term durability requires continued evaluation. Establishing a definitive clinical role will require larger prospective studies with extended follow-up.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13558525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Onyx-only superior rectal artery embolisation for bleeding internal haemorrhoids: initial single-centre experience. 单纯玛瑙直肠上动脉栓塞治疗内痔出血:最初的单中心经验。
IF 2.1
CVIR Endovascular Pub Date : 2026-09-07 DOI: 10.1186/s42155-026-00767-8
Luis Loureiro, Paulo Almeida, Samuel Cardoso, Romaric Loffroy, Rui Machado
{"title":"Onyx-only superior rectal artery embolisation for bleeding internal haemorrhoids: initial single-centre experience.","authors":"Luis Loureiro, Paulo Almeida, Samuel Cardoso, Romaric Loffroy, Rui Machado","doi":"10.1186/s42155-026-00767-8","DOIUrl":"10.1186/s42155-026-00767-8","url":null,"abstract":"<p><strong>Purpose: </strong>To report an initial single-centre experience with Onyx-18-only superior rectal artery embolisation for bleeding internal haemorrhoids, focusing on technical feasibility, treatment laterality, and updated clinical outcomes.</p><p><strong>Materials and methods: </strong>Consecutive Onyx-only procedures performed between October 2023 and April 2026 in patients with bleeding-predominant internal haemorrhoids were retrospectively reviewed. Patients with portal hypertension/cirrhosis were excluded because of the distinct pathophysiology of anorectal bleeding. Patient-level clinical outcomes and procedure-level technical variables were analysed separately. Updated telephone follow-up was obtained on 12 August 2026.</p><p><strong>Results: </strong>Six patients underwent 9 procedures. Technical success was achieved in all procedures. Three patients were treated bilaterally at the initial session and 3 initially unilaterally; 2 of the latter required staged contralateral embolisation. At updated follow-up, all 6 patients reported absence of rectal bleeding after completion of treatment. Median follow-up was 19.5 months (range, 4-34), and 5 of 6 patients had at least 12 months of follow-up. One transient episode of rectal pain occurred; no major or clinically evident ischaemic complication was observed.</p><p><strong>Conclusion: </strong>Onyx-only haemorrhoidal artery embolisation was technically feasible with encouraging updated bleeding control. The observed association between bilateral treatment and fewer staged procedures is hypothesis-generating and may partly reflect an operator learning curve.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"9 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13550264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书