CVIR EndovascularPub Date : 2025-05-19DOI: 10.1186/s42155-025-00560-z
Vagner Navasardyan, Maria Katz, Lukas Goertz, Vazgen Zohranyan, Hayk Navasardyan, Iram Shahzadi, Jan Robert Kröger, Jan Borggrefe
{"title":"Accuracy of segment anything model for classification of vascular stenosis in digital subtraction angiography.","authors":"Vagner Navasardyan, Maria Katz, Lukas Goertz, Vazgen Zohranyan, Hayk Navasardyan, Iram Shahzadi, Jan Robert Kröger, Jan Borggrefe","doi":"10.1186/s42155-025-00560-z","DOIUrl":"10.1186/s42155-025-00560-z","url":null,"abstract":"<p><strong>Background: </strong>This retrospective study evaluates the diagnostic performance of an optimized comprehensive multi-stage framework based on the Segment Anything Model (SAM), which we named Dr-SAM, for detecting and grading vascular stenosis in the abdominal aorta and iliac arteries using digital subtraction angiography (DSA).</p><p><strong>Materials and methods: </strong>A total of 100 DSA examinations were conducted on 100 patients. The infrarenal abdominal aorta (AAI), common iliac arteries (CIA), and external iliac arteries (EIA) were independently evaluated by two experienced radiologists using a standardized 5-point grading scale. Dr-SAM analyzed the same DSA images, and its assessments were compared with the average stenosis grading provided by the radiologists. Diagnostic accuracy was evaluated using Cohen's kappa, specificity, sensitivity, and Wilcoxon signed-rank tests.</p><p><strong>Results: </strong>Interobserver agreement between radiologists, which established the reference standard, was strong (Cohen's kappa: CIA right = 0.95, CIA left = 0.94, EIA right = 0.98, EIA left = 0.98, AAI = 0.79). Dr-SAM showed high agreement with radiologist consensus for CIA (κ = 0.93 right, 0.91 left), moderate agreement for EIA (κ = 0.79 right, 0.76 left), and fair agreement for AAI (κ = 0.70). Dr-SAM demonstrated excellent specificity (up to 1.0) and robust sensitivity (0.67-0.83). Wilcoxon tests revealed no significant differences between Dr-SAM and radiologist grading (p > 0.05).</p><p><strong>Conclusion: </strong>Dr-SAM proved to be an accurate and efficient tool for vascular assessment, with the potential to streamline diagnostic workflows and reduce variability in stenosis grading. Its ability to deliver rapid and consistent evaluations may contribute to earlier detection of disease and the optimization of treatment strategies. Further studies are needed to confirm these findings in prospective settings and to enhance its capabilities, particularly in the detection of occlusions.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"45"},"PeriodicalIF":1.2,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CVIR EndovascularPub Date : 2025-05-17DOI: 10.1186/s42155-025-00566-7
Omar Abu-Fares, Antonis Adamou, Heinrich Lanfermann, Joachim K Krauss, Shadi Al-Afif, Katja Döring
{"title":"Pipeline flow diverter and transvenous coiling for the treatment of direct carotid cavernous sinus fistulae: a retrospective case series.","authors":"Omar Abu-Fares, Antonis Adamou, Heinrich Lanfermann, Joachim K Krauss, Shadi Al-Afif, Katja Döring","doi":"10.1186/s42155-025-00566-7","DOIUrl":"10.1186/s42155-025-00566-7","url":null,"abstract":"<p><strong>Background: </strong>Carotid cavernous fistulae (CCF) are pathological connections between the carotid arteries and the cavernous sinus. Endovascular procedures are the mainstay treatment for CCF. The aim of this report is to evaluate the efficacy and safety of the combined use of the Pipeline Vantage (PV) flow diverter and transvenous coil embolization in the treatment of CCF.</p><p><strong>Methods: </strong>Retrospective,monocentric analysis of three patients who underwent neurointerventional treatment of clinically symptomatic CCF using a combination of transvenous coil embolization and flow diverter Implantation. Clinical data, the etiology of the CCF and clinical and radiological follow up were evaluated.</p><p><strong>Results: </strong>Clinical and radiological follow-up were available at 3 and 12 months. One patient experienced clinical improvement immediatley after the interventions. The other two patients improved within one year after treatment. No symptomatic complications were recorded. One year after the intervention complete CCF occulsion was documented in all cases.</p><p><strong>Conclusions: </strong>We report an initial experience for the treatment of direct CCF using the combination of a new generation Pipeline FD and transvenous coil embolization. The high treatment success rate and low complication rate are encouraging.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"44"},"PeriodicalIF":1.2,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CVIR EndovascularPub Date : 2025-05-15DOI: 10.1186/s42155-025-00543-0
Robert Wise, Zahi Qamhawi, Emma Wilton, Andrew Wigham
{"title":"Iliofemoral DVT thrombectomy: a dual-access approach to optimise inflow.","authors":"Robert Wise, Zahi Qamhawi, Emma Wilton, Andrew Wigham","doi":"10.1186/s42155-025-00543-0","DOIUrl":"10.1186/s42155-025-00543-0","url":null,"abstract":"","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"43"},"PeriodicalIF":1.2,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Learning curve in the endovascular treatment of chronic post-thrombotic syndrome in a French center.","authors":"Paul Segui, Valérie Monnin-Barès, Monira Nou, Sébastien Bommart, Hamid Zarqane, Juliette Vanoverschelde, Hélène Vernhet-Kovacsik","doi":"10.1186/s42155-025-00561-y","DOIUrl":"10.1186/s42155-025-00561-y","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic post-thrombotic syndrome (PTS) is a frequent and disabling complication of deep vein thrombosis (DVT) with significant clinical impact. Endovascular stenting (EVS) has established itself as an effective technique but its availability remains limited to expert centers. We sought to identify the key determinants of our learning curve in EVS for PTS and the impact of this experience on our short and long-term results, in order to facilitate territorial dissemination and respond effectively to clinical demand.</p><p><strong>Material and methods: </strong>We reviewed the records of 68 patients treated in our centre during eight years. We collected patients and disease characteristics, technical elements of the procedure, peri-procedural medical management and detail of the clinical follow-up and imaging.</p><p><strong>Results: </strong>The median follow-up was 37 months. The primary, primary assisted and secondary patency rates were respectively 74%, 86% and 95%. A clinical benefit was observed in all patients from the start of our activity, without significant change whatever the operator experience. The main determinants of our learning curve were a progressive mastery of the procedure in its technicality and preparation, the evolution of the material and the improvement of the peri procedural management, allowing to reduce the duration of intervention, the rate of endovascular revision (38% to 4%, p < 0.01) but also the number of remote thrombotic events (29% to 6%).</p><p><strong>Conclusion: </strong>EVS appears to be an effective therapeutic option in the management of PTS, with consistent clinical improvement observed even when performed by less experienced operators. Improvement in this technique comes with faster procedures, and a reduction of the occurrence of peri-procedural and long term thrombotic events. The implementation of this type of procedure requires multi-disciplinary collaboration with vascular medicine and corresponding angiologists.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"42"},"PeriodicalIF":1.2,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CVIR EndovascularPub Date : 2025-05-14DOI: 10.1186/s42155-025-00558-7
Nan Wei, René Michael Mathy, De-Hua Chang, Martin Loos, Uta Merle, Annika Gauss, Monica Boxberger, Philipp Mayer, Miriam Klauss, Hans-Ulrich Kauczor, Osman Öcal, Mark O Wielpütz
{"title":"Endovascular management of acute superior mesenteric vein thrombosis: a retrospective study on thrombolysis outcomes.","authors":"Nan Wei, René Michael Mathy, De-Hua Chang, Martin Loos, Uta Merle, Annika Gauss, Monica Boxberger, Philipp Mayer, Miriam Klauss, Hans-Ulrich Kauczor, Osman Öcal, Mark O Wielpütz","doi":"10.1186/s42155-025-00558-7","DOIUrl":"10.1186/s42155-025-00558-7","url":null,"abstract":"<p><strong>Background: </strong>Acute superior mesenteric vein thrombosis (ASMVT) is a rare but life-threatening condition associated with high morbidity and mortality. While anticoagulation remains the standard treatment, endovascular therapies such as thrombolysis, thrombectomy, and angioplasty are increasingly utilized in selected cases. However, evidence on their outcomes remains limited. This study retrospectively reports the clinical outcomes of ASMVT patients treated with endovascular combination therapies.</p><p><strong>Methods: </strong>Between August 2019 and May 2024, 12 patients (males = 9; mean age, 52.33 ± 12.51 years) were diagnosed with ASMVT. The study collected comprehensive data on demographic details, presenting symptoms, etiology, treatment modalities, response to treatment, and follow-up outcomes. Computed Tomography (CT) was available from diagnosis, and an average of 6.3 CT scans with a median follow-up of 3 months (IQR: 2-20 months).</p><p><strong>Results: </strong>The average time from symptom onset to angiographic treatment initiation was 8.0 ± 4.71 days, preceded by anticoagulation with heparin from the time of diagnosis. Patients were treated with combination therapy involving endovascular thrombolysis, rheolytic thrombectomy, and balloon angioplasty via transjugular (n = 9, 75%) or percutaneous (n = 3, 25%) approaches. Thrombolysis was performed with an average recombinant tissue plasminogen activator (rt-PA) infusion duration of 2.75 ± 1.14 days and a total dose of 61.25 ± 18.48 mg rt-PA. Superior mesenteric vein (SMV) flow was initially restored almost completely in 58.3% and partially in 41.7% of patients. Complications observed were hepatic artery bleeding (n = 2, 16.7%), hepatic arteriovenous fistula (n = 1, 8.3%), hepatic parenchymal bleeding (n = 1, 8.3%), melena (n = 1, 8.3%), and nostril bleeding (n = 1, 8.3%). Two patients experienced worsening symptoms of post-intervention, leading to bowel resection revealing intestinal necrosis. SMV patency was almost complete in 25%, and partially in 25% of patients at follow-up.</p><p><strong>Conclusion: </strong>Endovascular combination therapy with long-term thrombolysis and thrombectomy in patients with ASMVT demonstrated promising technical outcomes. In view of complications, individual indication for intervention needs to be confirmed in a multidisciplinary team.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"41"},"PeriodicalIF":1.2,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bronchial artery embolization for the treatment of hemoptysis: permanent versus temporary embolic materials, a single center study.","authors":"Taninokuchi Tomassoni Makoto, Perini Daniele, Porta Francesco, Braccischi Lorenzo, Zanella Sara, Basile Antonio, Modestino Francesco, Mosconi Cristina","doi":"10.1186/s42155-025-00554-x","DOIUrl":"https://doi.org/10.1186/s42155-025-00554-x","url":null,"abstract":"<p><strong>Background: </strong>Bronchial artery embolization (BAE) is a common interventional radiology technique used to control significant bleeding from the bronchial circulation, especially in cases of severe hemoptysis or pulmonary hemorrhage. The choice of embolizing agents plays a key role in the success, recurrence of bleeding, and safety of the procedure. However, there is no consensus on the ideal embolizing agent. This study compares the efficacy, safety, and long-term outcomes of using permanent versus temporary embolizing agents in BAE.</p><p><strong>Methods: </strong>This retrospective cohort study included patients who underwent BAE at our institution from July 2006 to May 2024. Inclusion criteria encompassed patients with hemoptysis requiring intervention, complete clinical and radiological data, and BAE with either permanent (e.g., coils, PVA particles) or temporary (e.g., gelatin sponge) embolic materials. Exclusion criteria included non-bronchial causes of hemoptysis, BAE as part of a lung transplant protocol, or use of combined embolic materials. Primary outcomes included early clinical success (cessation of bleeding during the procedure and no recurrence within a week) and late clinical success (no bleeding recurrence within 6 months). Secondary outcomes focused on procedural complications, such as pneumonia, lung infarction, or bronchial ischemia.</p><p><strong>Results: </strong>This retrospective study included a total of ninety-four procedures performed in eighty-five patients (56 males, 29 females; mean age 59; age range 8-92 years) who were admitted for BAE between July 2006 and May 2024. Permanent embolic materials were used in 59 procedures (64%), in most cases were used particles and glue (39% and 21%, respectively), while temporary embolizing materials (gelatin sponge) were used in 35 procedures (37%). Statistical analysis showed a superiority in terms of clinical outcomes in favor of permanent embolic materials (p-value 0,047).</p><p><strong>Conclusions: </strong>BAE is a safe procedure for control of hemoptysis of varying etiologies and possesses high rates of immediate clinical success with few complications. In terms of embolic materials, a superiority in term of late clinical success and lower hemorrhage recurrency rate with permanent materials were clearly observed in our population, with a similar safety profile. Further studies are needed to confirm our findings and strengthen evidence.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"40"},"PeriodicalIF":1.2,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CVIR EndovascularPub Date : 2025-05-06DOI: 10.1186/s42155-025-00542-1
Ola Sobhy A Elmeseiny, Simon Winther, Hanne Skou Jørgensen, My Svensson, Morten Bøttcher, Per Ivarsen, Gratien Andersen, Henrik Birn, Marie Bodilsen Nielsen
{"title":"Assessment of aortic and iliac artery calcification using CT-angiography in kidney transplant candidates.","authors":"Ola Sobhy A Elmeseiny, Simon Winther, Hanne Skou Jørgensen, My Svensson, Morten Bøttcher, Per Ivarsen, Gratien Andersen, Henrik Birn, Marie Bodilsen Nielsen","doi":"10.1186/s42155-025-00542-1","DOIUrl":"https://doi.org/10.1186/s42155-025-00542-1","url":null,"abstract":"<p><strong>Purpose: </strong>Assessment of vascular calcification provides the opportunity for risk stratification in kidney transplant candidates (KTCs), as vascular calcification constitutes an independent risk factor for cardiovascular events. The aim of the present study is to explore the feasibility of contrast enhanced computed tomography (CT)-angiography to quantitate vascular calcification, to avoid the extra radiation of an additional non-contrast CT scan.</p><p><strong>Methods and materials: </strong>43 KTCs who underwent concomitant non-contrast CT scans and CT-angiographies of the infrarenal aorta and iliac arteries were included. Vascular calcification was quantified using the Agatston method on non-contrast CT and applying individual Hounsfield Unit thresholds on CT-angiographies based on the radio density of the aortic lumen. The calcium scores and volumes from non-contrast CT scans and CT-angiographies were compared using linear regression and Bland-Altman plots.</p><p><strong>Results: </strong>Non-contrast CT revealed vascular calcification in the infrarenal aorta in 92% of KTCs and in the iliac arteries in 90% of KTCs. The calcium scores estimated from CT-angiography correlated linearly with the calcium scores based on non-contrast CT scans (infrarenal aorta: R<sup>2</sup> = 0.71, p < 0.0001; iliac arteries: R<sup>2</sup> = 0.71, p < 0.0001); however, the calcium scores were higher, and volumes were lower compared to the non-contrast CT scans. The median differences in calcium scores were 1517 [48 - 6138] for the infrarenal aorta, and 2361 [59 - 8644] for the iliac arteries.</p><p><strong>Conclusion: </strong>Vascular calcification is present in the majority of KTCs. Calcification of the infrarenal aorta and iliac arteries may be assessed using CT-angiography, though higher calcium scores and lower volumes are found compared to the non-contrast CT scan.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"39"},"PeriodicalIF":1.2,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endovascular treatment of a descending thoracic aorta aneurysm in a patient with right sided aortic arch: a case report.","authors":"Nefeli Ntinou, Panagiotis Petaloudis, Dimitra Tachmetzidi Papoutsi, Vasileios Panou, Myrto Papadopoulou, Dimitrios Tomais, Ioannis Kalogeropoulos, Theodoros Kratimenos","doi":"10.1186/s42155-025-00526-1","DOIUrl":"https://doi.org/10.1186/s42155-025-00526-1","url":null,"abstract":"<p><strong>Backround: </strong>Right-sided aortic arch is a rare congenital variant. The Edwards classification describes three types of right sided-aortic arch: right aortic arch with aberrant left subclavian artery, right aortic arch with mirror image branching, and right aortic arch with isolation of the left subclavian artery. Aneurysms associated with right sided aortic arch are rare. Pain is the commonest presenting symptom, but due to the anatomy of the right aortic arch, the symptoms may be atypical, as dysphagia. We present a case of a challenging endovascular repair in a patient with aneurysm of descending thoracic aorta and right aortic arch.</p><p><strong>Case presentation: </strong>Α 55 year old patient was admitted in our hospital with chest pain. After the initial clinical and laboratory workout that was negative for acute coronary syndrome, Computed Tomography Angiography revealed an aneurysm of the descending aorta 10,3 cm in width, and a right sided aortic arch (Edwards' classification). Endovascular repair was selected as the treatment option of choice. Technically the endografting was challenging, firstly because of the right sided aortic arch, secondly because the four aortic branches originate independently. In order to identify the orifices of arch vessels during the angiography, brachial access in both upper extremities was achieved. In this way, it was possible to correctly deploy the thoracic aortic stent graft. No endoleaks were observed in the final angiography. Postoperative Computed Tomography Angiography 10 months after the operation showed no endoleaks.</p><p><strong>Conclusion: </strong>This case indicates that TEVAR is feasible as a treatment option in patients with right-sided aortic arch, even though technically is challenging. However more evidence-based data are needed to certify long-term safety and efficacy of endovascular repair in treatment of thoracic aortic aneurysm associated with right-sided aortic arch.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"38"},"PeriodicalIF":1.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CVIR EndovascularPub Date : 2025-05-03DOI: 10.1186/s42155-025-00553-y
John C DuBois, Aaron M Rohr, Ian T Kozlowski, Zachary S Collins
{"title":"Endovascular treatment of a ruptured portal vein pseudoaneurysm secondary to a large stomach ulcer.","authors":"John C DuBois, Aaron M Rohr, Ian T Kozlowski, Zachary S Collins","doi":"10.1186/s42155-025-00553-y","DOIUrl":"https://doi.org/10.1186/s42155-025-00553-y","url":null,"abstract":"<p><p>This case describes the endovascular treatment of a 55-year old female with a ruptured portal vein pseudoaneurysm secondary to a large stomach ulcer resulting in massive active hemorrhage into the adjacent stomach. This patient presented with persistent hypotension secondary to chronic GI blood loss and simultaneous septic shock. After an abrupt drop in blood pressure, the patient arrived in the angiography suite where the ruptured pseudoaneurysm was apparent on portal venogram. Emergent stent assisted coil embolization was performed to stabilize the patient and treat the portal vein pseudoaneurysm. To our knowledge, this case presents the only portal vein pseudoaneurysm secondary to a gastric ulcer.Level of Evidence Level 4, Case-report.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"37"},"PeriodicalIF":1.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CVIR EndovascularPub Date : 2025-05-01DOI: 10.1186/s42155-025-00555-w
Osman Ahmed, John Karageorgiou, Abhishek Kumar, Mikin Patel, Joshua Jones, Nariman Nezami
{"title":"Real-world clinical experience with Obsidio Conformable Embolic.","authors":"Osman Ahmed, John Karageorgiou, Abhishek Kumar, Mikin Patel, Joshua Jones, Nariman Nezami","doi":"10.1186/s42155-025-00555-w","DOIUrl":"https://doi.org/10.1186/s42155-025-00555-w","url":null,"abstract":"<p><strong>Background: </strong>Obsidio Conformable Embolic (Obsidio) is a ready-made hydrogel with unique shear-thinning properties, used for occlusion of blood flow to control bleeding or hemorrhage in the peripheral vasculature and embolization of hypervascular tumors. While pre-clinical and clinical data have demonstrated successful embolizations using Obsidio, clinical experience overall is still limited, prompting a multi-institutional field assessment survey to collect additional data on the clinical utility and procedural details from a variety of Obsidio users. The field survey collected data from 131 embolization procedures performed using Obsidio between May and November 2023 at 27 institutions within the United States. Data collection included embolization site, vessel size, any adjunctive embolics used. The primary objective of the survey was to evaluate technical success, defined as complete embolization of the target vasculature immediately following the index procedure, as confirmed by angiography.</p><p><strong>Results: </strong>Of the 131 embolization procedures performed, 69% (n = 90) were for hemorrhage control, 15% (n = 19) were for hypervascular tumors, and 17% (n = 22) were for other indications. Embolization of the gastroduodenal artery was the most common indication (n = 19/131; 15%). A single syringe (1 mL) or less of Obsidio was used for most cases (93%). In 33/131 cases (25%), Obsidio was combined with other embolization devices including coils (n = 25; 19%), particle-based embolics (n = 6; 4.6%), or plugs (n = 2; 1.5%). Technical success was achieved in 100% of Obsidio embolization cases (131/131 procedures).</p><p><strong>Conclusion: </strong>Initial clinical experience demonstrated successful embolization of end-organ bleeds and hypervascular tumors utilizing Obsidio, thus making it an effective embolic agent alone or in conjunction with other embolic devices.</p>","PeriodicalId":52351,"journal":{"name":"CVIR Endovascular","volume":"8 1","pages":"36"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}