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Current Opinion in Endocrine and Metabolic Research最新文献

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Thyroid cancer—Editorial overview
Current Opinion in Endocrine and Metabolic Research Pub Date : 2025-01-25 DOI: 10.1016/j.coemr.2025.100573
Jennifer A Sipos, Vicki E Smith
{"title":"Thyroid cancer—Editorial overview","authors":"Jennifer A Sipos, Vicki E Smith","doi":"10.1016/j.coemr.2025.100573","DOIUrl":"10.1016/j.coemr.2025.100573","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100573"},"PeriodicalIF":0.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights into the role of adipose tissue-derived microRNAs in intercellular communication during cardiometabolic diseases
Current Opinion in Endocrine and Metabolic Research Pub Date : 2025-01-22 DOI: 10.1016/j.coemr.2025.100572
Henver S. Brunetta , Stepheny C. de Campos Zani , Gabriel P. Ruiz , Marcelo A. Mori
{"title":"Insights into the role of adipose tissue-derived microRNAs in intercellular communication during cardiometabolic diseases","authors":"Henver S. Brunetta ,&nbsp;Stepheny C. de Campos Zani ,&nbsp;Gabriel P. Ruiz ,&nbsp;Marcelo A. Mori","doi":"10.1016/j.coemr.2025.100572","DOIUrl":"10.1016/j.coemr.2025.100572","url":null,"abstract":"<div><div>microRNAs (miRNAs) secreted by the adipose tissue (AT) have gained substantial attention over the last decade. Adipocytes produce and secrete large amounts of miRNAs that, in turn, can mediate physiological processes paracrinally or in distant organs. It is now clear that AT-derived miRNAs are important players in the development of obesity-associated comorbidities. Here, we provide an overview that supports this notion and bring insights into the intricate involvement of AT-derived miRNAs in the pathogenesis of cardiometabolic diseases, discussing some of their far-reaching effects on the liver, heart, vasculature, and other tissues. Moreover, we outline future research directions addressing current gaps in the field which we hope will further advance our comprehension of the role of AT-derived miRNAs.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100572"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endocrine microbiology: A transdisciplinary approach of the human physiology
Current Opinion in Endocrine and Metabolic Research Pub Date : 2025-01-15 DOI: 10.1016/j.coemr.2025.100570
Marc G.J. Feuilloley, Olivier Lesouhaitier
{"title":"Endocrine microbiology: A transdisciplinary approach of the human physiology","authors":"Marc G.J. Feuilloley,&nbsp;Olivier Lesouhaitier","doi":"10.1016/j.coemr.2025.100570","DOIUrl":"10.1016/j.coemr.2025.100570","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100570"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex hormones–Gut microbiome axis: An update of what is known so far
Current Opinion in Endocrine and Metabolic Research Pub Date : 2025-01-11 DOI: 10.1016/j.coemr.2025.100571
Mohamed Zommiti, Marc G.J. Feuilloley
{"title":"Sex hormones–Gut microbiome axis: An update of what is known so far","authors":"Mohamed Zommiti,&nbsp;Marc G.J. Feuilloley","doi":"10.1016/j.coemr.2025.100571","DOIUrl":"10.1016/j.coemr.2025.100571","url":null,"abstract":"<div><div>The human gut microbiota is known to be shaped by a wide range of extrinsic factors (geography, lifestyle, sanitation, diet and drugs) and host intrinsic factors (genetics, age, sexual development and sex hormones). The intricate connection between organs, including glands, and different microbiota is well established with emerging evidence linking gut microbiota, composition, diversity and/or function as a key contributor to gut-organ/gland axis signaling. The observed differences in gut microbiota (GM) composition and diversity have led to numerous investigations highlighting the interaction between steroid hormones and the gut microbiome. In this review, we shed the light on how sex steroid hormones may modulate the composition and the function of the gut microbiota and vice-versa, via focusing on a unique crosstalk between these two main actors. We also highlight the role of the gut microbiota in modulating sex steroids signaling along the gut microbiome-sex hormones axis. Altogether, the evidence implies that gonadal steroids and gut microbiota exert a pivotal role in shifting host bacterial action, given the relevance of these factors in directly impacting physiology, metabolism, reproductive efficiency and even in the development of various ailments in both animals and humans.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100571"},"PeriodicalIF":0.0,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143200765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Therapeutic treatments targeting communication between angiogenic and immune microenvironments in thyroid cancers” [Curr Opin Endocrine Metabol Res 37 (December 2024) 100544]
Current Opinion in Endocrine and Metabolic Research Pub Date : 2024-12-06 DOI: 10.1016/j.coemr.2024.100569
Alessandro Prete , Carmelo Nucera
{"title":"Corrigendum to “Therapeutic treatments targeting communication between angiogenic and immune microenvironments in thyroid cancers” [Curr Opin Endocrine Metabol Res 37 (December 2024) 100544]","authors":"Alessandro Prete ,&nbsp;Carmelo Nucera","doi":"10.1016/j.coemr.2024.100569","DOIUrl":"10.1016/j.coemr.2024.100569","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"38 ","pages":"Article 100569"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial board page 编委会页面
Current Opinion in Endocrine and Metabolic Research Pub Date : 2024-12-01 DOI: 10.1016/S2451-9650(24)00061-9
{"title":"Editorial board page","authors":"","doi":"10.1016/S2451-9650(24)00061-9","DOIUrl":"10.1016/S2451-9650(24)00061-9","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"37 ","pages":"Article 100563"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adipose tissue-derived mediators of systemic inflammation and metabolic control 源自脂肪组织的全身炎症和代谢控制介质
Current Opinion in Endocrine and Metabolic Research Pub Date : 2024-10-28 DOI: 10.1016/j.coemr.2024.100560
Vasileia Ismini Alexaki
{"title":"Adipose tissue-derived mediators of systemic inflammation and metabolic control","authors":"Vasileia Ismini Alexaki","doi":"10.1016/j.coemr.2024.100560","DOIUrl":"10.1016/j.coemr.2024.100560","url":null,"abstract":"<div><div>Obesity increases the risk for a number of diseases, including type 2 diabetes, liver and cardiovascular disease, or neurological disorders. Low-grade chronic systemic inflammation typically accompanying obesity is considered driving these disorders. The inflammatory factors produced by the hypertrophic adipose tissue can have systemic effects. The present review summarizes current knowledge on the most investigated in this context, inflammatory cytokines: Tumor necrosis factor (TNF), interleukin 6 (IL6), IL1β, and interferon γ. Their metabolic effects on organs such as the liver, the skeletal muscle, the pancreas and the brain, and therapeutic interventions targeting systemic inflammation in obesity are discussed.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"37 ","pages":"Article 100560"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142707074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Regulation of adipose-derived fatty acid flux to the liver”-Impact on metabolic dysfunction-associated steatotic liver disease "脂肪源性脂肪酸流向肝脏的调节"--对代谢功能障碍相关脂肪肝的影响
Current Opinion in Endocrine and Metabolic Research Pub Date : 2024-10-28 DOI: 10.1016/j.coemr.2024.100559
Erika Folestad, Annelie Falkevall
{"title":"“Regulation of adipose-derived fatty acid flux to the liver”-Impact on metabolic dysfunction-associated steatotic liver disease","authors":"Erika Folestad,&nbsp;Annelie Falkevall","doi":"10.1016/j.coemr.2024.100559","DOIUrl":"10.1016/j.coemr.2024.100559","url":null,"abstract":"<div><div>Obesity is now considered a global epidemic, increasing the prevalence of obesity-related metabolic disorders. Obesity is characterized by an increase in white adipose tissue (WAT) mass that induce local inflammation and insulin resistance in the WAT, causing dysregulation of whole-body homeostasis. WAT is the primary organ for energy storage in the form of triacylglycerols, which are released as fatty acids (FAs) upon energy demand, a process named lipolysis. Under chronic high energy intake, adipocytes can expand to accommodate more triacylglycerols but when the storage capacity is impaired or lipolysis is dysregulated, FAs are redirected to other organs. The systemic overload of FAs contributes to the development of obesity-associated metabolic complications such as metabolic dysfunction-associated steatotic fatty liver disease (MASLD), formerly named non-alcoholic fatty liver disease. This minireview aims to discuss adipose-derived FA flux as a determinator for development of MASLD from an adipocentric perspective, underlining the contribution of WAT dysfunction in this disease.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"37 ","pages":"Article 100559"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142707073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial overview: Cilia and endocrinology 编辑综述：纤毛与内分泌学
Current Opinion in Endocrine and Metabolic Research Pub Date : 2024-10-23 DOI: 10.1016/j.coemr.2024.100558
Rex A. Hess, Clémence Belleannée
{"title":"Editorial overview: Cilia and endocrinology","authors":"Rex A. Hess,&nbsp;Clémence Belleannée","doi":"10.1016/j.coemr.2024.100558","DOIUrl":"10.1016/j.coemr.2024.100558","url":null,"abstract":"","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"37 ","pages":"Article 100558"},"PeriodicalIF":0.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of human communications molecules on respiratory tractus bacterial pathogen 人类通讯分子对呼吸道细菌病原体的影响
Current Opinion in Endocrine and Metabolic Research Pub Date : 2024-10-18 DOI: 10.1016/j.coemr.2024.100557
Olivier Lesouhaitier, Adrien Forge, Anne-Sophie Tareau, Mathieu Gonzalez, Sylvie Chevalier, Ali Tahrioui
{"title":"Impact of human communications molecules on respiratory tractus bacterial pathogen","authors":"Olivier Lesouhaitier,&nbsp;Adrien Forge,&nbsp;Anne-Sophie Tareau,&nbsp;Mathieu Gonzalez,&nbsp;Sylvie Chevalier,&nbsp;Ali Tahrioui","doi":"10.1016/j.coemr.2024.100557","DOIUrl":"10.1016/j.coemr.2024.100557","url":null,"abstract":"<div><div>The rapid increase of bacteria becoming resistant to antibiotics means that alternative solutions to antibiotics must be found urgently. This observation particularly concerns respiratory pathogens such as <em>Pseudomonas aeruginosa</em>, <em>Acinetobacter baumanii</em>, or <em>Staphylococcus aureus</em>. Microbial endocrinology has paved a new way to identify specific bacterial targets related to several human communication molecules such as neurotransmitters, cytokines, and hormones. Here, we describe these human signaling compounds that are able to modify the physiology of major respiratory bacterial pathogens and their potential mechanism of action on bacteria. This review aims to better understand the effects of human communication molecules on the physiology of major respiratory bacterial pathogens and their consequences in terms of virulence, persistence, and interference with the action of antibiotics. These data should be considered to avoid promoting chronic infections in patients or to optimize antibiotic treatment.</div></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"37 ","pages":"Article 100557"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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