Colloid Journal最新文献_第7页

Study of Cryostructuring of Polymer System. 65. Features of Changes in the Physicochemical Properties of Poly(vinyl alcohol) Cryogels Caused by the Action of Aqueous Solutions of Amino Acids of General Formula H2N–(CH2)n–COOH 聚合物体系的冷冻结构研究。65.通式为 H2N-(CH2)n-COOH 的氨基酸水溶液作用下聚乙烯醇冷凝凝胶理化性质变化的特征

IF 1.1 4区化学

Colloid Journal Pub Date : 2024-01-26 DOI: 10.1134/s1061933x23600781

O. Yu. Kolosova, A. S. Ryzhova, V. P. Chernyshev, V. I. Lozinsky

{"title":"Study of Cryostructuring of Polymer System. 65. Features of Changes in the Physicochemical Properties of Poly(vinyl alcohol) Cryogels Caused by the Action of Aqueous Solutions of Amino Acids of General Formula H2N–(CH2)n–COOH","authors":"O. Yu. Kolosova, A. S. Ryzhova, V. P. Chernyshev, V. I. Lozinsky","doi":"10.1134/s1061933x23600781","DOIUrl":"https://doi.org/10.1134/s1061933x23600781","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>Macroporous cryogels of poly(vinyl alcohol) (PVA) have been prepared by the cryogenic processing (freezing at –20°C for 12 h followed by defrosting through heating at a rate of 0.03°C/min) of aqueous PVA solutions with a polymer concentration of 100 g/L. The character of changes in the physicochemical parameters of the cryogels has been studied after equilibrating their samples with aqueous solutions of amino acids of general formula H<sub>2</sub>N–(CH<sub>2</sub>)<sub><i>n</i></sub>–COOH (<i>n</i> = 1–5). It has been shown that these amino acids, glycine (<i>n</i> = 1) and ε-aminocaproic acid (<i>n</i> = 5) to the highest and lowest extent, respectively, impose a kosmotropic action on the properties of the PVA cryogels causing a decrease in their volume, a significant increase in the compression elasticity modulus, and a rise in the fusion temperature of the samples. Nevertheless, H<sub>2</sub>N–(CH<sub>2</sub>)<sub><i>n</i></sub>–COOH amino acids are released from the cryogels saturated with amino acid solutions into an external aqueous environment with no significant diffusion hindrances. After cryogels loaded with amino acids are exhaustively rinsed with pure water, their physicochemical parameters do not return completely to the values observed for the samples before their treatment with solutions of such amino acids due to the formation of additional H-bonded nodes of a three-dimensional network, with their formation being promoted by kosmotropic amino acids in the bulk of the already formed cryogels.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139580758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanochemical Synthesis of Ethoxyaminohumic Acids and Surface-Active Properties of Their Solutions at Solution–Air Interface 乙氧基氨基铝酸的机械化学合成及其溶液在溶液-空气界面上的表面活性特性

IF 1.1 4区化学

Colloid Journal Pub Date : 2024-01-26 DOI: 10.1134/s1061933x23600963

S. L. Khil’ko, V. S. Shelest, M. I. Rogatko, R. A. Makarova, R. G. Semenova

{"title":"Mechanochemical Synthesis of Ethoxyaminohumic Acids and Surface-Active Properties of Their Solutions at Solution–Air Interface","authors":"S. L. Khil’ko, V. S. Shelest, M. I. Rogatko, R. A. Makarova, R. G. Semenova","doi":"10.1134/s1061933x23600963","DOIUrl":"https://doi.org/10.1134/s1061933x23600963","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">\u0000<b>Abstract</b>—</h3><p>Ethoxyamine derivatives of humic acids have been obtained by mechanochemical synthesis via the simultaneous interaction of humic acids with poly(ethylene glycol) (PEG-6000 and PEG-1500) and an aminating reagent (urea, hydroperitum, or cyanoguanidine) in a vibrating apparatus. Reaction products have been characterized by IR spectroscopy, acid–base potentiometric titration, and viscometry. Tensiometric and rheological characteristics of the surface layers of solutions of salts of the synthesized derivatives of humic acids have been studied by the pendant drop and oscillating pendant drop methods. The solutions of the salts of ethoxyaminohumic acids have been found to exhibit a pronounced surface activity at the air–water interface. The experimental dependences of the viscoelastic modulus on the surface pressure and the concentration of the solutions of ethoxyaminohumic acid salts are in satisfactory agreement with the functions calculated in terms of the theoretical model of bimolecular adsorption. The presence of amino groups in the structure of ethoxyaminohumic acids predetermines their high solubility in the acidic pH region. The simultaneous incorporation of ethoxy and amino groups into humic acid macromolecules makes it possible to obtain a novel type of surfactants, which combine three functions, i.e., the functions of anionic, cationic, and nonionic surfactants.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139590451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stabilization of Swellable Aluminosilicate Suspensions 稳定可膨胀硅酸铝悬浮液

IF 1.1 4区化学

Colloid Journal Pub Date : 2024-01-26 DOI: 10.1134/s1061933x2360094x

K. A. Ovchinnikov, E. V. Podlesnova, F. E. Safarov, A. T. Akhmetov, A. V. Fakhreeva, E. I. Gusarova, N. A. Sergeeva, A.G. Telin

{"title":"Stabilization of Swellable Aluminosilicate Suspensions","authors":"K. A. Ovchinnikov, E. V. Podlesnova, F. E. Safarov, A. T. Akhmetov, A. V. Fakhreeva, E. I. Gusarova, N. A. Sergeeva, A.G. Telin","doi":"10.1134/s1061933x2360094x","DOIUrl":"https://doi.org/10.1134/s1061933x2360094x","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The goal of this study is to increase the energy efficiency of pipeline hydraulic transport of water-swellable aluminosilicate dispersions. A model commercial suspension, the filler of which is a complex mixture of aluminosilicates, has been used to develop an approach that makes it possible to improve the technological properties of such suspensions. Modification of the suspensions consists in adding organic and inorganic inhibitors of swelling of dispersed phase particles, as well as nonionic surfactants. The influence of the additives leads to a decrease in the yield stress and an increase in sedimentation stability of the heterogeneous systems. It has been shown that the use of the complex modifying additive prevents the particles of the model suspension from agglomeration and provides it with sedimentation stability at temperatures up to 70°C, which is important for the technical process in which the suspension is intended to be used. Technically, the research is of an applied nature. A well-known approach to modifying suspensions is used, which consists in combating the aggregation of dispersed phase particles and blocking ion exchange between them and the dispersion medium. The performed set of rheological shear and oscillation tests and the study of the sedimentation stability of the suspensions in the presence of various modifying additives have resulted in optimizing their composition. The practical result of the work is the successful hydrotransport of the suspension in which the content of the dispersed phase is 50% higher than that in the unmodified suspension, thus increasing the energy efficiency of the process.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139580944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic Properties of Pulmonary Lipid Monolayers on the Surfaces of Sodium Polystyrene Sulfonate and Polydiallyldimethylammonium Chloride Solutions 聚苯乙烯磺酸钠和聚二烯丙基二甲基氯化铵溶液表面肺脂质单层的动态特性

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x23600677

A. G. Bykov, M. A. Panaeva

引用次数: 0

Nanoemulsions and Solid Lipid Nanoparticles with Encapsulated Doxorubicin and Thymoquinone 包裹多柔比星和胸腺醌的纳米乳液和固体脂质纳米颗粒

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x23600707

E. V. Mishchenko, A. M. Gileva, E. A. Markvicheva, M. Yu. Koroleva

{"title":"Nanoemulsions and Solid Lipid Nanoparticles with Encapsulated Doxorubicin and Thymoquinone","authors":"E. V. Mishchenko, A. M. Gileva, E. A. Markvicheva, M. Yu. Koroleva","doi":"10.1134/s1061933x23600707","DOIUrl":"https://doi.org/10.1134/s1061933x23600707","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">\u0000<b>Abstract</b>—</h3><p>Nanoemulsions (NEs) and solid lipid nanoparticles (SLNs) are promising drug delivery systems. In this work, paraffin oil NEs and stearic acid SLNs stabilized with Tween 60 and Span 60 have been studied. NEs with an average droplet diameter of ~50 nm and suspensions of SLNs with an average size of ~30 nm are stable to aggregation for more than 90 days. The rates of penetration of lipid particles into cancer cells (C6 and MCF-7) depend on their sizes. After incubation for 1 h, lipid nanoparticles ~50 nm in size penetrate into cells, are distributed in their internal space, and concentrate in the nuclei. The cytotoxicity of doxorubicin- or thymoquinone-loaded NEs and SLNs against MCF-7 and HTC 116 cell lines is higher than the cytotoxicity of the individual substances. Wherein, unloaded NEs and SLNs show low cytotoxicity. The obtained results demonstrate that paraffin oil NEs and stearic acid SLNs are promising to be used as carriers of both lipophilic and amphiphilic drugs, including doxorubicin and thymoquinone. The accumulation of lipid nanoparticles with sizes smaller than 100 nm in cell nuclei is an advantage of such systems for the delivery of anticancer drugs, because this leads to DNA replication suppression followed by cell apoptosis.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138631086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stimuli-Responsive Drug Delivery Systems Based on Bilayer Lipid Vesicles: New Trends 基于双层脂质囊泡的刺激响应型给药系统：新趋势

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x23600690

A. A. Efimova, A. V. Sybachin

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Enzyme-Like Activity of Cerium Dioxide Colloidal Solutions Stabilized with L-Malic Acid 用 L-苹果酸稳定的二氧化铈胶体溶液的酶样活性

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x23600653

A. D. Filippova, A. E. Baranchikov, V. K. Ivanov

引用次数: 0

Lipid Nanoparticles for Lutein Encapsulation and Delivery 用于叶黄素封装和输送的脂质纳米颗粒

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x2360063x

A. D. Shirokikh, Y. A. Guruleva, E. A. Marinets, M. Y. Koroleva

{"title":"Lipid Nanoparticles for Lutein Encapsulation and Delivery","authors":"A. D. Shirokikh, Y. A. Guruleva, E. A. Marinets, M. Y. Koroleva","doi":"10.1134/s1061933x2360063x","DOIUrl":"https://doi.org/10.1134/s1061933x2360063x","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>Recently, lipid nanoparticles have been intensively studied as carriers of lipophilic drugs. In this work, we have studied the stability of nanoemulsions with paraffin oil, solid lipid nanoparticles with stearic acid, and nanostructured lipid particles with paraffin oil and stearic acid in a mass ratio of 1 : 1. The obtained results have shown that all studied lipid systems stabilized with nonionic surfactants Tween 60 and Span 60 were stable to aggregation and subsequent sedimentation for more than 30 days. The incorporation of lutein into the lipid particles has almost no effect on their stability, while the size of solid lipid nanoparticles and nanostructured lipid nanoparticles decreases from 28–30 to 15–17 nm. The bioavailability of lutein loaded in lipid nanoparticles is evaluated from their effect on the restoration of blood flow velocity by simulating hemic hypoxia. Almost immediately after the application of lipid nanoparticles, the blood flow velocity ceases to decrease, and a tendency to its restoration is observed in 5–10 min. This shows that lipid nanoparticles with paraffin oil and stearic acid are promising candidates for the delivery of lipophilic drugs.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138630807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoparticle Concentration as an Important Parameter for Characterization of Dispersion and Its Applications in Biomedicine 纳米粒子浓度作为表征分散性的重要参数及其在生物医学中的应用

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x23600720

T. N. Pashirova, Z. M. Shaihutdinova, E. B. Souto, P. Masson, V. F. Mironov

{"title":"Nanoparticle Concentration as an Important Parameter for Characterization of Dispersion and Its Applications in Biomedicine","authors":"T. N. Pashirova, Z. M. Shaihutdinova, E. B. Souto, P. Masson, V. F. Mironov","doi":"10.1134/s1061933x23600720","DOIUrl":"https://doi.org/10.1134/s1061933x23600720","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>Currently, there are problems to standardize methods for determining the concentration of nanoparticles and creation of etalon materials for calibrating measured concentrations. Accurate determination of nanoparticle concentration is necessary to assess the maximum dose of administered nanotherapeutics for diagnostics and therapy in vivo, to determine the order of reaction in enzymatic nanoreactors. In addition, this parameter determines biological effects, such as the formation of a protein corona on the outer surface of nanoparticles that precedes nanoparticles’ absorption and internalization in cells. This review discusses the most common methods for determining the concentration of nanoparticles based on direct visualization, using microscopy, light absorption or light scattering, direct counting of nanoparticles, and gravimetry. Results may differ from one method to the other. Thus, the use of a combination of several methods provides more reliable results. The advantages, disadvantages and ways to improve accuracy of results are also presented.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138630821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biocompatible Hydrogels Based on Biodegradable Polyesters and Their Copolymers 基于生物可降解聚酯及其共聚物的生物相容性水凝胶

IF 1.1 4区化学

Colloid Journal Pub Date : 2023-12-12 DOI: 10.1134/s1061933x23600756

Yu. S. Fomina, A. S. Semkina, Yu. D. Zagoskin, M. M. Aleksanyan, S. N. Chvalun, T. E. Grigoriev

引用次数: 0